JP2013532629A5 - - Google Patents
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- JP2013532629A5 JP2013532629A5 JP2013519107A JP2013519107A JP2013532629A5 JP 2013532629 A5 JP2013532629 A5 JP 2013532629A5 JP 2013519107 A JP2013519107 A JP 2013519107A JP 2013519107 A JP2013519107 A JP 2013519107A JP 2013532629 A5 JP2013532629 A5 JP 2013532629A5
- Authority
- JP
- Japan
- Prior art keywords
- imaging
- composition according
- nano
- sized particles
- particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000003384 imaging method Methods 0.000 claims description 26
- 238000002591 computed tomography Methods 0.000 claims description 7
- 238000002600 positron emission tomography Methods 0.000 claims description 4
- 238000002595 magnetic resonance imaging Methods 0.000 claims description 3
- 238000002603 single-photon emission computed tomography Methods 0.000 claims description 3
- 230000005855 radiation Effects 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims 20
- 239000002245 particle Substances 0.000 claims 17
- 239000002105 nanoparticle Substances 0.000 claims 12
- 210000001519 tissue Anatomy 0.000 claims 8
- 239000007787 solid Substances 0.000 claims 7
- 239000010931 gold Substances 0.000 claims 6
- 150000001875 compounds Chemical class 0.000 claims 5
- 229910052751 metal Inorganic materials 0.000 claims 4
- 239000002184 metal Substances 0.000 claims 4
- 229910052797 bismuth Inorganic materials 0.000 claims 3
- JCXGWMGPZLAOME-UHFFFAOYSA-N bismuth atom Chemical compound [Bi] JCXGWMGPZLAOME-UHFFFAOYSA-N 0.000 claims 3
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims 3
- 229910052737 gold Inorganic materials 0.000 claims 3
- 238000002786 image-guided radiation therapy Methods 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- 239000002202 Polyethylene glycol Substances 0.000 claims 2
- 239000011575 calcium Substances 0.000 claims 2
- 238000000576 coating method Methods 0.000 claims 2
- 239000002872 contrast media Substances 0.000 claims 2
- 239000010410 layer Substances 0.000 claims 2
- 150000002632 lipids Chemical class 0.000 claims 2
- 239000002502 liposome Substances 0.000 claims 2
- 239000011777 magnesium Substances 0.000 claims 2
- 229920001223 polyethylene glycol Polymers 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 1
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims 1
- 239000000232 Lipid Bilayer Substances 0.000 claims 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims 1
- 229910052788 barium Inorganic materials 0.000 claims 1
- DSAJWYNOEDNPEQ-UHFFFAOYSA-N barium atom Chemical compound [Ba] DSAJWYNOEDNPEQ-UHFFFAOYSA-N 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 229910052791 calcium Inorganic materials 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 229920006037 cross link polymer Polymers 0.000 claims 1
- 239000000412 dendrimer Substances 0.000 claims 1
- 229920000736 dendritic polymer Polymers 0.000 claims 1
- 238000000799 fluorescence microscopy Methods 0.000 claims 1
- 239000000416 hydrocolloid Substances 0.000 claims 1
- 239000013554 lipid monolayer Substances 0.000 claims 1
- 210000004880 lymph fluid Anatomy 0.000 claims 1
- 229910052749 magnesium Inorganic materials 0.000 claims 1
- 239000002923 metal particle Substances 0.000 claims 1
- 239000000693 micelle Substances 0.000 claims 1
- 238000003333 near-infrared imaging Methods 0.000 claims 1
- 230000005298 paramagnetic effect Effects 0.000 claims 1
- 229920000575 polymersome Polymers 0.000 claims 1
- 230000035755 proliferation Effects 0.000 claims 1
- 230000002285 radioactive effect Effects 0.000 claims 1
- 230000008685 targeting Effects 0.000 claims 1
- 210000004881 tumor cell Anatomy 0.000 claims 1
- 238000002604 ultrasonography Methods 0.000 claims 1
- 238000013170 computed tomography imaging Methods 0.000 description 3
- 230000003211 malignant effect Effects 0.000 description 3
- 238000001959 radiotherapy Methods 0.000 description 2
- 230000002596 correlated effect Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36491710P | 2010-07-16 | 2010-07-16 | |
| EP10169862.9 | 2010-07-16 | ||
| EP10169862 | 2010-07-16 | ||
| US61/364,917 | 2010-07-16 | ||
| PCT/EP2011/062122 WO2012007567A1 (en) | 2010-07-16 | 2011-07-15 | Nanoparticle-guided radiotherapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013532629A JP2013532629A (ja) | 2013-08-19 |
| JP2013532629A5 true JP2013532629A5 (https=) | 2015-12-10 |
Family
ID=43063934
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013519107A Pending JP2013532629A (ja) | 2010-07-16 | 2011-07-15 | ナノ粒子誘導放射線治療 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20130204121A1 (https=) |
| EP (1) | EP2593186A1 (https=) |
| JP (1) | JP2013532629A (https=) |
| CN (1) | CN103079642A (https=) |
| AU (1) | AU2011278308B2 (https=) |
| BR (1) | BR112013000907A2 (https=) |
| CA (1) | CA2804849A1 (https=) |
| MX (1) | MX2013000501A (https=) |
| WO (1) | WO2012007567A1 (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2782603A1 (en) | 2011-11-25 | 2014-10-01 | Danmarks Tekniske Universitet | Formulation of solid nano-sized particles in a gel-forming system |
| US9370490B2 (en) | 2012-02-28 | 2016-06-21 | Loma Linda University | Methods for the production, modification and use of metallic nanoparticles |
| WO2013164725A1 (en) | 2012-05-02 | 2013-11-07 | Koninklijke Philips N.V. | Spectral ct visualization of imageable drug eluting beads |
| US10035009B2 (en) | 2013-04-15 | 2018-07-31 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and methods for treating pancreatic cancer |
| RU2703303C2 (ru) * | 2013-05-24 | 2019-10-16 | Данмаркс Текниске Университет | Состав геля для лучевой терапии под визуальным контролем |
| FR3018451A1 (fr) * | 2014-03-13 | 2015-09-18 | Chromalys | Nanoparticules pour leur utilisation dans la detection de tumeurs mobiles |
| CN103894557B (zh) * | 2014-03-19 | 2016-01-20 | 丽水市中心医院 | 磁共振成像下可视的功能化金纳米粒子的制备方法及应用 |
| US10004695B2 (en) | 2014-04-16 | 2018-06-26 | Trustees Of Boston University | GM3 functionalized nanoparticles |
| WO2016004222A1 (en) * | 2014-07-01 | 2016-01-07 | Georgia Regents University | Bio-compatible radiopaque dental fillers for imaging |
| JP6501191B2 (ja) * | 2014-12-02 | 2019-04-17 | シグマテクノロジー有限会社 | マイクロ・ナノバブルによる洗浄方法及び洗浄装置 |
| WO2016115140A1 (en) * | 2015-01-13 | 2016-07-21 | Boston Scientific Scimed, Inc. | Cancer cell membrane depolarization |
| WO2016137013A1 (ja) * | 2015-02-26 | 2016-09-01 | 国立大学法人北海道大学 | 放射線治療用の病変識別マーカーおよび放射線治療用の病変識別マーカーキット |
| CA3015663A1 (en) * | 2016-03-07 | 2017-09-14 | Memorial Sloan Kettering Cancer Center | Bone marrow-, reticuloendothelial system-, and/or lymph node-targeted radiolabeled liposomes and methods of their diagnostic and therapeutic use |
| KR102162400B1 (ko) * | 2016-05-13 | 2020-10-06 | 시그마 테크놀로지 유겐가이샤 | 생체 투여 가능한 수용액 및 그 제조 방법 |
| EP3500311B1 (en) | 2016-08-16 | 2020-05-27 | ETH Zurich | Transmembrane ph-gradient polymersomes and their use in the scavenging of ammonia and its methylated analogs |
| US20190201557A1 (en) * | 2016-08-25 | 2019-07-04 | National University Corporation Hokkaido University | Lesion identification marker utilizing bone cement for use in radiation therapy, and lesion identification marker kit for use in radiation therapy |
| WO2019028453A1 (en) * | 2017-08-04 | 2019-02-07 | The Cleveland Clinic Foundation | RADIATION THERAPY WITH TEMPORAL ATTENUATION |
| DK3668927T3 (da) | 2017-09-12 | 2024-03-25 | Eth Zuerich | Transmembran ph-gradient polymersom til kvantificering af ammoniak i kropsvæsker |
| IL265914B (en) * | 2019-04-08 | 2020-11-30 | Convergent R N R Ltd | System and method for optimization of radiotherapy treatments |
| FR3099052B1 (fr) * | 2019-07-23 | 2022-03-25 | Univ Franche Comte | Structures particulaires à base de nanoparticules d’or, leurs procédés de préparation et leurs utilisations dans le traitement des tumeurs solides |
| US10929981B1 (en) * | 2019-08-21 | 2021-02-23 | Ping An Technology (Shenzhen) Co., Ltd. | Gross tumor volume segmentation method and computer device |
| US12082956B2 (en) * | 2019-09-09 | 2024-09-10 | Universidad De La Frontera | Integral systems of orthovoltage sources that induce ionizing radiation |
| CN111467174B (zh) * | 2019-12-20 | 2023-02-17 | 联影(常州)医疗科技有限公司 | 一种头部固定装置、血管减影造影系统及透射方法 |
| IT202000001048A1 (it) | 2020-01-21 | 2021-07-21 | Univ Degli Studi Padova | Nanoparticelle multifunzionali a base di nanoleghe metalliche per usi diagnostici e terapeutici. |
| IT202100001049A1 (it) | 2021-01-21 | 2022-07-21 | Univ Degli Studi Padova | Nanoparticelle multifunzionali a base di nanoleghe metalliche per usi diagnostici e terapeutici. |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6818199B1 (en) * | 1994-07-29 | 2004-11-16 | James F. Hainfeld | Media and methods for enhanced medical imaging |
| US6645464B1 (en) * | 1998-07-30 | 2003-11-11 | James F. Hainfeld | Loading metal particles into cell membrane vesicles and metal particular use for imaging and therapy |
| JP4282302B2 (ja) * | 2001-10-25 | 2009-06-17 | 株式会社東芝 | Ｘ線ｃｔ装置 |
| WO2003075961A2 (en) * | 2002-03-08 | 2003-09-18 | James Hainfeld | Gold nanoparticles used for x-rays imaging |
| WO2004017814A2 (en) | 2002-08-23 | 2004-03-04 | The Board Of Regents Of University Of Texas System | Novel method and composition of identifying inflammation by cat scan |
| GB2395882B (en) * | 2002-11-28 | 2006-06-14 | Elekta Ab | Radiotherapy apparatus and operating method |
| JP4247533B2 (ja) * | 2003-09-03 | 2009-04-02 | 国立大学法人東京工業大学 | 呼吸同期装置 |
| WO2005046733A1 (en) * | 2003-11-17 | 2005-05-26 | Philips Intellectual Property & Standards Gmbh | Contrast agent for medical imaging techniques and usage thereof |
| US20070031337A1 (en) * | 2004-06-22 | 2007-02-08 | Reinhard Schulte | Nanoparticle enhanced proton computed tomography and proton therapy |
| WO2006084382A1 (en) | 2005-02-11 | 2006-08-17 | University Health Network | Compositions and methods for multimodal imaging |
| DE102005018330B4 (de) * | 2005-04-20 | 2007-04-19 | Siemens Ag | System zur Erzeugung von CT-Bilddatensätzen und zur Bestrahlung eines Tumor-Patienten |
| GB0519391D0 (en) * | 2005-09-22 | 2005-11-02 | Aion Diagnostics Ltd | Imaging agents |
| WO2007129311A2 (en) | 2006-05-04 | 2007-11-15 | Pan Sci Tech S.A. | Nano-particles with contrast agents for diagnostic delivery system for x-ray and ct |
| KR100810679B1 (ko) * | 2006-05-09 | 2008-03-07 | 원광대학교산학협력단 | 금 나노입자를 이용한 엑스-선 조영제 및 이의 제조방법 |
| US7906147B2 (en) * | 2006-10-12 | 2011-03-15 | Nanoprobes, Inc. | Functional associative coatings for nanoparticles |
| US20080213189A1 (en) * | 2006-10-17 | 2008-09-04 | The Board Of Trustees Of The Leland Stanford Junior University | Multifunctional metal-graphite nanocrystals |
| WO2008096279A1 (en) * | 2007-02-07 | 2008-08-14 | Spago Imaging Ab | Compositions containing metal oxide particles and their uses |
| US20090088625A1 (en) * | 2007-10-01 | 2009-04-02 | Kenneth Oosting | Photonic Based Non-Invasive Surgery System That Includes Automated Cell Control and Eradication Via Pre-Calculated Feed-Forward Control Plus Image Feedback Control For Targeted Energy Delivery |
| CN101868180A (zh) * | 2007-10-09 | 2010-10-20 | 圣路易斯华盛顿州立大学 | 成像粒子 |
| US20110104052A1 (en) * | 2007-12-03 | 2011-05-05 | The Johns Hopkins University | Methods of synthesis and use of chemospheres |
| WO2009155431A1 (en) * | 2008-06-18 | 2009-12-23 | University Of Louisville Research Foundation, Inc. | Methods for targeted cancer treatment and detection |
| US8784800B2 (en) * | 2009-03-09 | 2014-07-22 | Medtronic, Inc. | Method of delivering cell therapy to a target site |
| DK3223013T3 (en) * | 2009-07-02 | 2019-04-15 | Sloan Kettering Inst Cancer Res | FLUORESCING SILICA-BASED NANOPARTICLES |
-
2011
- 2011-07-15 MX MX2013000501A patent/MX2013000501A/es unknown
- 2011-07-15 CN CN2011800423725A patent/CN103079642A/zh active Pending
- 2011-07-15 EP EP11731392.4A patent/EP2593186A1/en not_active Withdrawn
- 2011-07-15 US US13/810,588 patent/US20130204121A1/en not_active Abandoned
- 2011-07-15 WO PCT/EP2011/062122 patent/WO2012007567A1/en not_active Ceased
- 2011-07-15 BR BR112013000907A patent/BR112013000907A2/pt not_active IP Right Cessation
- 2011-07-15 AU AU2011278308A patent/AU2011278308B2/en not_active Ceased
- 2011-07-15 JP JP2013519107A patent/JP2013532629A/ja active Pending
- 2011-07-15 CA CA2804849A patent/CA2804849A1/en not_active Abandoned
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