JP2013527126A - ヒドロキシチロソール化合物 - Google Patents

ヒドロキシチロソール化合物 Download PDF

Info

Publication number
JP2013527126A
JP2013527126A JP2012530349A JP2012530349A JP2013527126A JP 2013527126 A JP2013527126 A JP 2013527126A JP 2012530349 A JP2012530349 A JP 2012530349A JP 2012530349 A JP2012530349 A JP 2012530349A JP 2013527126 A JP2013527126 A JP 2013527126A
Authority
JP
Japan
Prior art keywords
hydroxytyrosol
polymer
antioxidant
product
polymer compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2012530349A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013527126A5 (enExample
Inventor
バートン，ステファニー・ゲイル
デイビッズ，レスター・マーリン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Cape Town
Original Assignee
University of Cape Town
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Cape Town filed Critical University of Cape Town
Publication of JP2013527126A publication Critical patent/JP2013527126A/ja
Publication of JP2013527126A5 publication Critical patent/JP2013527126A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A61K9/0017—Non-human animal skin, e.g. pour-on, spot-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/18—Antioxidants, e.g. antiradicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G61/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G61/02—Macromolecular compounds containing only carbon atoms in the main chain of the macromolecule, e.g. polyxylylenes
    • C08G61/10—Macromolecular compounds containing only carbon atoms in the main chain of the macromolecule, e.g. polyxylylenes only aromatic carbon atoms, e.g. polyphenylenes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/34—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives
    • C08G65/38—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives derived from phenols
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2261/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G2261/10—Definition of the polymer structure
    • C08G2261/14—Side-groups
    • C08G2261/142—Side-chains containing oxygen
    • C08G2261/1422—Side-chains containing oxygen containing OH groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2261/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G2261/30—Monomer units or repeat units incorporating structural elements in the main chain
    • C08G2261/31—Monomer units or repeat units incorporating structural elements in the main chain incorporating aromatic structural elements in the main chain
    • C08G2261/312—Non-condensed aromatic systems, e.g. benzene
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2261/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G2261/50—Physical properties
    • C08G2261/59—Stability
    • C08G2261/594—Stability against light, i.e. electromagnetic radiation
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2261/00—Macromolecular compounds obtained by reactions forming a carbon-to-carbon link in the main chain of the macromolecule
    • C08G2261/50—Physical properties
    • C08G2261/59—Stability
    • C08G2261/596—Stability against oxidation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2012530349A 2009-09-22 2010-09-22 ヒドロキシチロソール化合物 Pending JP2013527126A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ZA200906592 2009-09-22
PCT/IB2010/002373 WO2011036537A1 (en) 2009-09-22 2010-09-22 Hydroxytyrosol compounds

Publications (2)

Publication Number Publication Date
JP2013527126A true JP2013527126A (ja) 2013-06-27
JP2013527126A5 JP2013527126A5 (enExample) 2013-08-08

Family

ID=43795454

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012530349A Pending JP2013527126A (ja) 2009-09-22 2010-09-22 ヒドロキシチロソール化合物

Country Status (6)

Country Link
US (1) US8663608B2 (enExample)
EP (1) EP2480223A4 (enExample)
JP (1) JP2013527126A (enExample)
CN (1) CN102665702A (enExample)
WO (1) WO2011036537A1 (enExample)
ZA (1) ZA201202288B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101945987B1 (ko) 2018-03-19 2019-02-08 주식회사 엑티브온 티로솔을 포함하는 피부 외용제용 보존제, 이를 포함하는 화장료 조성물 및 약학 조성물

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9334229B2 (en) 2013-11-04 2016-05-10 Eastman Chemical Company Hydroxytyrosol derivatives, their method of preparation and use in personal care
CN106987098B (zh) * 2017-05-04 2019-06-11 中国林业科学研究院林产化学工业研究所 一类高抗氧化和热稳定性的羟基酪醇聚合物及其制备方法
CN109929227B (zh) * 2019-04-03 2021-09-24 哈工大机器人（山东）智能装备研究院 一种可降解的芹菜纤维复合材料及其制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4013A (en) * 1845-04-26 Machine fqe making match-splihts and arranging them in dipping
US6437004B1 (en) * 2000-04-06 2002-08-20 Nicholas V. Perricone Treatment of skin damage using olive oil polyphenols

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6602527B1 (en) 2000-11-22 2003-08-05 Thomas J. Slaga Processing method for manufacturing black tea and an improved black tea

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4013A (en) * 1845-04-26 Machine fqe making match-splihts and arranging them in dipping
US6437004B1 (en) * 2000-04-06 2002-08-20 Nicholas V. Perricone Treatment of skin damage using olive oil polyphenols

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
JPN6014020867; Ｃｕｒｒｅｎｔ　Ｏｒｇａｎｉｃ　Ｃｈｅｍｉｓｔｒｙ Ｖｏｌ．１２, 2008, ｐｐ．４４２-４６３ *
JPN6014020868; Ｏｒｇａｎｉｃ　＆　Ｂｉｏｍｏｌｅｃｕｌａｒ　Ｃｈｅｍｉｓｔｒｙ Ｖｏｌ．３，　Ｎｏ．３, 20050207, ｐｐ．４２３-４３０ *
JPN6014020870; Ｔｅｔｒａｈｅｄｒｏｎ Ｖｏｌ．６２, 2006, ｐｐ．１２７３-１２７８ *
JPN6014020871; Ｎａｔｕｒａｌ　Ｐｒｏｄｕｃｔ　Ｒｅｓｅａｒｃｈ Ｖｏｌ．２０，　Ｎｏ．９, 20060720, ｐｐ．７９２-７９７ *
JPN6014020873; Ｐｈｙｔｏｃｈｅｍｉｃａｌ　Ａｎａｌｙｓｉｓ Ｖｏｌ．１５，　Ｎｏ．３, 200405, ｐｐ．１８４-１８８ *
JPN6014020874; Ｎａｔｕｒａｌ　Ｐｒｏｄｕｃｔ　Ｌｅｔｔｅｒｓ Ｖｏｌ．１４，　Ｎｏ．６, 2000, ｐｐ．４２９-４３４ *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101945987B1 (ko) 2018-03-19 2019-02-08 주식회사 엑티브온 티로솔을 포함하는 피부 외용제용 보존제, 이를 포함하는 화장료 조성물 및 약학 조성물

Also Published As

Publication number Publication date
WO2011036537A1 (en) 2011-03-31
US8663608B2 (en) 2014-03-04
CN102665702A (zh) 2012-09-12
EP2480223A4 (en) 2013-02-27
ZA201202288B (en) 2012-11-28
US20120269745A1 (en) 2012-10-25
EP2480223A1 (en) 2012-08-01

Similar Documents

Publication Publication Date Title
Wei et al. Certain (−)-epigallocatechin-3-gallate (EGCG) auto-oxidation products (EAOPs) retain the cytotoxic activities of EGCG
Sonmez et al. Synthesis, antioxidant activity and SAR study of novel spiro-isatin-based Schiff bases
Nabavi et al. Protective effect of gallic acid isolated from Peltiphyllum peltatum against sodium fluoride-induced oxidative stress in rat’s kidney
Francioso et al. Chemistry, stability and bioavailability of resveratrol
Lohézic-Le Dévéhat et al. Lichenic extracts and metabolites as UV filters
Mischenko et al. Echinamines A and B, First Aminated Hydroxynaphthazarins from the Sea Urchin Scaphechinus m irabilis
Dietz et al. Xanthohumol isolated from Humulus lupulus inhibits menadione-induced DNA damage through induction of quinone reductase
Handoussa et al. Anti-inflammatory and cytotoxic activities of dietary phenolics isolated from Corchorus olitorius and Vitis vinifera
Grynkiewicz et al. Curcumin and curcuminoids in quest for medicinal status
Jing et al. Effect of glycosylation patterns of Chinese eggplant anthocyanins and other derivatives on antioxidant effectiveness in human colon cell lines
Allegra et al. Mechanism of interaction of betanin and indicaxanthin with human myeloperoxidase and hypochlorous acid
Liang et al. Natural sulforaphane as a functional chemopreventive agent: including a review of isolation, purification and analysis methods
Wang et al. Exploring post-translational arginine modification using chemically synthesized methylglyoxal hydroimidazolones
Menna et al. Anthracycline degradation in cardiomyocytes: a journey to oxidative survival
Tabrizi et al. Antioxidant and anticancer properties of functionalized ferrocene with hydroxycinnamate derivatives—an integrated experimental and theoretical study
Valença et al. Synthesis of quinone‐based N‐sulfonyl‐1, 2, 3‐triazoles: chemical reactivity of Rh (II) azavinyl carbenes and antitumor activity
Van Chen et al. Antioxidant activity and α-glucosidase inhibitability of Distichochlamys citrea MF Newman rhizome fractionated extracts: in vitro and in silico screenings
Grkovic et al. Cryptocaryols A–H, α-pyrone-containing 1, 3-polyols from Cryptocarya sp. implicated in stabilizing the tumor suppressor Pdcd4
Kang et al. Cytoprotective effect of tectorigenin, a metabolite formed by transformation of tectoridin by intestinal microflora, on oxidative stress induced by hydrogen peroxide
US20260062555A1 (en) Selenium-containing analogues of pheomelanin and related materials and methods of making
Detenchuk et al. Transformation of resveratrol under disinfection conditions
Hasan et al. Synthesis, characterization and efficacy of mitochondrial targeted delivery of TPP-curcumin in rotenone-induced toxicity
US8663608B2 (en) Hydroxytyrosol compounds
Dubuisson et al. Discovery and validation of a new family of antioxidants: the aminopyrazine derivatives
Dang et al. Activatable NIR-II fluorescent nanoprobe for rapid detection and imaging of methylglyoxal facilitated by the local nonpolar microenvironment

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130522

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20130522

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20140527

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20141125