JP2013520990A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2013520990A5 JP2013520990A5 JP2012556068A JP2012556068A JP2013520990A5 JP 2013520990 A5 JP2013520990 A5 JP 2013520990A5 JP 2012556068 A JP2012556068 A JP 2012556068A JP 2012556068 A JP2012556068 A JP 2012556068A JP 2013520990 A5 JP2013520990 A5 JP 2013520990A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- antibody fragment
- mab
- seq
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 11
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 11
- 102100022005 B-lymphocyte antigen CD20 Human genes 0.000 claims 7
- 101000897405 Homo sapiens B-lymphocyte antigen CD20 Proteins 0.000 claims 7
- 238000000034 method Methods 0.000 claims 6
- 241000282324 Felis Species 0.000 claims 3
- 241001465754 Metazoa Species 0.000 claims 3
- 201000010099 disease Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 241000282465 Canis Species 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 208000027866 inflammatory disease Diseases 0.000 claims 2
- 230000035755 proliferation Effects 0.000 claims 2
- 102000013135 CD52 Antigen Human genes 0.000 claims 1
- 108010065524 CD52 Antigen Proteins 0.000 claims 1
- 206010012438 Dermatitis atopic Diseases 0.000 claims 1
- 241000282326 Felis catus Species 0.000 claims 1
- 206010025323 Lymphomas Diseases 0.000 claims 1
- 230000010056 antibody-dependent cellular cytotoxicity Effects 0.000 claims 1
- 206010003246 arthritis Diseases 0.000 claims 1
- 238000003556 assay Methods 0.000 claims 1
- 201000008937 atopic dermatitis Diseases 0.000 claims 1
- 238000002512 chemotherapy Methods 0.000 claims 1
- 238000011260 co-administration Methods 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31044010P | 2010-03-04 | 2010-03-04 | |
| US61/310,440 | 2010-03-04 | ||
| PCT/US2011/000415 WO2011109108A1 (en) | 2010-03-04 | 2011-03-04 | Monoclonal antibodies directed to cd20 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016068492A Division JP2016179978A (ja) | 2010-03-04 | 2016-03-30 | Cd20に対するモノクローナル抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013520990A JP2013520990A (ja) | 2013-06-10 |
| JP2013520990A5 true JP2013520990A5 (enExample) | 2014-04-17 |
| JP5911813B2 JP5911813B2 (ja) | 2016-04-27 |
Family
ID=44542488
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012556068A Expired - Fee Related JP5911813B2 (ja) | 2010-03-04 | 2011-03-04 | Cd20に対するモノクローナル抗体 |
| JP2016068492A Pending JP2016179978A (ja) | 2010-03-04 | 2016-03-30 | Cd20に対するモノクローナル抗体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016068492A Pending JP2016179978A (ja) | 2010-03-04 | 2016-03-30 | Cd20に対するモノクローナル抗体 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9616120B2 (enExample) |
| EP (1) | EP2542262A4 (enExample) |
| JP (2) | JP5911813B2 (enExample) |
| AU (2) | AU2011221553B2 (enExample) |
| BR (1) | BR112012022338A2 (enExample) |
| CA (1) | CA2791560A1 (enExample) |
| WO (1) | WO2011109108A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010110838A2 (en) | 2009-03-25 | 2010-09-30 | Vet Therapeutics Inc. | Antibody constant domain regions and uses thereof |
| EP2496604B1 (en) * | 2009-11-06 | 2017-08-23 | IDEXX Laboratories, Inc. | Canine anti-cd20 antibodies |
| EP2542258A4 (en) | 2010-03-04 | 2013-08-21 | Vet Therapeutics Inc | ON CD52 MONOCLONAL ANTIBODIES |
| SG10201500957QA (en) * | 2011-05-06 | 2015-04-29 | Nvip Pty Ltd | Anti-nerve growth factor antibodies and methods of preparing and using the same |
| US9790280B2 (en) | 2011-10-26 | 2017-10-17 | Elanco Tiergesundheit Ag | Monoclonal canine CD20 antibodies and methods of use |
| AU2014368453B2 (en) | 2013-12-20 | 2020-04-16 | Intervet International B.V. | Caninized murine anti-canine PD-1 antibodies |
| ES2853823T3 (es) | 2014-09-30 | 2021-09-17 | Intervet Int Bv | Anticuerpos de PD-L1 que se unen a PD-L1 canino |
| CN114656573B (zh) | 2015-05-30 | 2024-09-27 | 分子模板公司 | 去免疫化的志贺毒素a亚基支架和包含它们的细胞靶向分子 |
| ES3014160T3 (en) | 2015-12-18 | 2025-04-21 | Intervet Int Bv | Caninized human antibodies to human and canine il-4r alpha |
| US11091556B2 (en) | 2015-12-18 | 2021-08-17 | Intervet Inc. | Caninized human antibodies to human IL-4R alpha |
| CA3014461C (en) * | 2016-02-18 | 2023-02-28 | Elanco Us Inc. | Chimeric canine anti-cd20 antibody |
| US11648265B2 (en) | 2016-08-10 | 2023-05-16 | Aurelius Biotherapeutics, Llc | Cell therapy compositions and methods of use thereof |
| CA3045944A1 (en) | 2016-12-07 | 2018-06-14 | Progenity, Inc. | Gastrointestinal tract detection methods, devices and systems |
| CA3054632A1 (en) | 2017-03-30 | 2018-10-04 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immune modulatory agent released using an ingestible device |
| JP2019026625A (ja) * | 2017-08-03 | 2019-02-21 | 日本全薬工業株式会社 | 抗イヌcd20モノクローナル抗体 |
| US12227565B2 (en) | 2018-06-20 | 2025-02-18 | Biora Therapeutics, Inc. | Method of formulating a pharmaceutical composition comprising administering an immune modulator to the small intestine |
| US20230041197A1 (en) | 2018-06-20 | 2023-02-09 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
| CN113348011B (zh) | 2018-11-19 | 2023-04-18 | 比奥拉治疗股份有限公司 | 用生物治疗剂治疗疾病的方法和装置 |
| CN114174336B (zh) * | 2019-07-15 | 2024-10-11 | 英特维特国际股份有限公司 | 针对人和犬ctla-4的犬源化抗体 |
| JP2021059499A (ja) * | 2019-10-03 | 2021-04-15 | 日本全薬工業株式会社 | イヌcd20に対するモノクローナル抗体又は抗体フラグメント |
| CN121197633A (zh) | 2019-12-13 | 2025-12-26 | 比特比德科有限责任公司 | 用于将治疗剂递送至胃肠道的可摄取装置 |
| GB202217993D0 (en) * | 2022-11-30 | 2023-01-11 | Petmedix Ltd | Therapeutic antibodies |
| WO2024158001A1 (ja) | 2023-01-25 | 2024-08-02 | 日本全薬工業株式会社 | イヌのb細胞リンパ腫の治療方法 |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| AU640397B2 (en) * | 1989-08-25 | 1993-08-26 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Dog-mouse heterohybridoma and gene fragment coding for constant region of canine immunoglobulin |
| US7084260B1 (en) * | 1996-10-10 | 2006-08-01 | Genpharm International, Inc. | High affinity human antibodies and human antibodies against human antigens |
| PT100379B (pt) * | 1991-04-10 | 1999-01-29 | Scripps Research Inst | Bibliotecas de receptores heterodimericos usando fagomideos |
| JP3919830B2 (ja) * | 1992-11-28 | 2007-05-30 | 財団法人化学及血清療法研究所 | 抗ネコヘルペスウイルス−1組換え抗体および該抗体をコードする遺伝子断片 |
| US5910486A (en) * | 1994-09-06 | 1999-06-08 | Uab Research Foundation | Methods for modulating protein function in cells using, intracellular antibody homologues |
| EP0803834A3 (en) * | 1996-04-25 | 2000-06-28 | Olympus Optical Co., Ltd. | Memory card installing device |
| US6306393B1 (en) * | 1997-03-24 | 2001-10-23 | Immunomedics, Inc. | Immunotherapy of B-cell malignancies using anti-CD22 antibodies |
| JP3087696B2 (ja) | 1997-07-25 | 2000-09-11 | 日本電気株式会社 | 分散メモリ型マルチプロセッサ・システム制御方法およびコンピュータ読み取り可能な記録媒体 |
| US6573372B2 (en) | 1999-01-07 | 2003-06-03 | Heska Corporation | Feline immunoglobulin E molecules and compositions there of |
| ES2288886T3 (es) | 1999-12-30 | 2008-02-01 | Dana-Farber Cancer Institute, Inc. | Proteoliposomas que contienen una proteina integral de membrana que tiene uno o mas dominios transmembrana. |
| US6703360B2 (en) * | 2000-04-07 | 2004-03-09 | Heska Corporation | Compositions and methods related to canine IgG and canine IL-13 receptors |
| GB0013810D0 (en) | 2000-06-06 | 2000-07-26 | Celltech Chiroscience Ltd | Biological products |
| US7117096B2 (en) | 2001-04-17 | 2006-10-03 | Abmaxis, Inc. | Structure-based selection and affinity maturation of antibody library |
| JP4723810B2 (ja) * | 2001-12-03 | 2011-07-13 | アレクシオン ファーマシューティカルズ, インコーポレイテッド | ハイブリッド抗体 |
| US7393648B2 (en) | 2001-12-03 | 2008-07-01 | Alexion Pharmaceuticals, Inc. | Hybrid antibodies |
| GB0129105D0 (en) | 2001-12-05 | 2002-01-23 | Celltech R&D Ltd | Expression control using variable intergenic sequences |
| CA2469833C (en) * | 2001-12-21 | 2008-05-20 | Idexx Laboratories, Inc. | Canine immunoglobulin variable domains, caninized antibodies, and methods for making and using them |
| CA2476166C (en) * | 2002-02-14 | 2011-11-15 | Immunomedics, Inc. | Anti-cd20 antibodies and fusion proteins thereof and methods of use |
| EP1476120B1 (en) | 2002-02-21 | 2010-09-29 | Duke University | Treatment methods using anti-cd22 antibodies |
| CN1678634A (zh) | 2002-06-28 | 2005-10-05 | 多曼蒂斯有限公司 | 免疫球蛋白单个变体抗原结合区及其特异性构建体 |
| DK1578446T3 (en) * | 2002-11-07 | 2015-06-29 | Immunogen Inc | ANTI-CD33 ANTIBODIES AND PROCEDURES FOR TREATING ACUTE MYELOID LEUKEMIA BY USING IT |
| EP1694706B1 (en) * | 2003-11-01 | 2012-04-04 | Merck Patent GmbH | Modified anti-cd52 antibody |
| JPWO2005075640A1 (ja) | 2004-02-10 | 2008-01-10 | 学校法人日本大学 | イヌcd20遺伝子 |
| EP1751187A2 (en) * | 2004-05-28 | 2007-02-14 | Idexx Laboratories, Inc. | Canine cd20 compositions |
| AU2005277641A1 (en) | 2004-08-16 | 2006-03-02 | Medimmune, Llc | Eph receptor Fc variants with enhanced antibody dependent cell-mediated cytotoxicity activity |
| AU2005335714B2 (en) | 2004-11-10 | 2012-07-26 | Macrogenics, Inc. | Engineering Fc antibody regions to confer effector function |
| JP5838021B2 (ja) * | 2005-04-15 | 2015-12-24 | マクロジェニクス,インコーポレーテッド | 共有結合型ダイアボディとその使用 |
| CN101238150A (zh) | 2005-05-24 | 2008-08-06 | 阿维斯塔金格兰技术有限公司 | 用于治疗慢性淋巴细胞性白血病的抗cd52单克隆抗体的重组生产方法 |
| DK2573114T3 (en) * | 2005-08-10 | 2016-07-04 | Macrogenics Inc | The identification and production of antibodies with variant Fc regions, and methods of using same |
| EA015992B1 (ru) * | 2006-03-17 | 2012-01-30 | Байоджен Айдек Эмэй Инк. | Стабилизированное антитело и многовалентная антигенсвязывающая молекула на его основе, способы получения и использования вышеназванного стабилизированного антитела |
| US20080112961A1 (en) | 2006-10-09 | 2008-05-15 | Macrogenics, Inc. | Identification and Engineering of Antibodies with Variant Fc Regions and Methods of Using Same |
| TW200831528A (en) * | 2006-11-30 | 2008-08-01 | Astrazeneca Ab | Compounds |
| GB0707640D0 (en) | 2007-04-20 | 2007-05-30 | Strathclyde | Acoustic deterrence |
| EP2331579B1 (en) | 2008-09-04 | 2017-07-05 | Vet Therapeutics, Inc. | Monoclonal antibodies |
| WO2010110838A2 (en) | 2009-03-25 | 2010-09-30 | Vet Therapeutics Inc. | Antibody constant domain regions and uses thereof |
| EP2542258A4 (en) * | 2010-03-04 | 2013-08-21 | Vet Therapeutics Inc | ON CD52 MONOCLONAL ANTIBODIES |
-
2011
- 2011-03-04 BR BR112012022338A patent/BR112012022338A2/pt not_active IP Right Cessation
- 2011-03-04 AU AU2011221553A patent/AU2011221553B2/en not_active Ceased
- 2011-03-04 WO PCT/US2011/000415 patent/WO2011109108A1/en not_active Ceased
- 2011-03-04 EP EP11751028.9A patent/EP2542262A4/en not_active Withdrawn
- 2011-03-04 CA CA2791560A patent/CA2791560A1/en not_active Abandoned
- 2011-03-04 JP JP2012556068A patent/JP5911813B2/ja not_active Expired - Fee Related
- 2011-03-15 US US13/048,135 patent/US9616120B2/en active Active
-
2016
- 2016-03-30 JP JP2016068492A patent/JP2016179978A/ja active Pending
- 2016-05-17 US US15/157,352 patent/US20170002084A1/en not_active Abandoned
- 2016-08-19 AU AU2016216710A patent/AU2016216710A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2013520999A5 (enExample) | ||
| CY1123791T1 (el) | Μονοκλωνικο αντισωμα ιντερλευκινης-31 | |
| AR084210A1 (es) | PROTEINAS DE UNION AL TNF-a | |
| NZ588713A (en) | Antibodies to receptor of advanced glycation end products (rage) and uses thereof | |
| BR112012022338A2 (pt) | anticorpos monoclonais direcionados a cd20 | |
| BR112012007365A2 (pt) | proteínas de ligação à il-1 | |
| SG194466A1 (en) | Non-human animals expressing antibodies having a common light chain | |
| WO2011050106A3 (en) | Anti-cd3 antibody dosing in autoimmune disease | |
| CY1119994T1 (el) | Συνθεσεις και μεθοδοι για αυξηση της μυϊκης μαζας και της μυϊκης δυναμης ανταγωνιζοντας ειδικα ton gdf8 και/ή την ακτιβινη α | |
| BRPI0916945A2 (pt) | métodos para tratar uma doença auto-imune ou distúrbio inflamatório em um indivíduo humano, para tratar esclerose múltipla em um indivíduo, e para identificar anticorpos, anticorpo humano, humanizado ou quimérico isolado ou um fragmento de ligação de antígeno do mesmo, e, proteína de ligação isolada. | |
| BR112013028523A8 (pt) | Uso de um anticorpo ou uma proteína de fusão ou um fragmento de ligação da mesma e método para a purificação de um anticorpo, uma proteína de fusão ou um fragmento de ligação da mesma de uma mistura fonte | |
| RU2016100892A (ru) | Антитела против tweakr и их применение | |
| JP2014503189A5 (enExample) | ||
| PE20180249A1 (es) | Anticuerpos neutralizadores anti-ccl20 | |
| AR095980A1 (es) | Anticuerpos biespecíficos específicos para fap (proteína de activación fibroblástica) y dr5 (receptor de muerte 5), anticuerpos específicos para dr5 y métodos de utilización | |
| MX2012004084A (es) | Anticuerpos siglec-15 para tratar enfermedad relacionada con perdida osea. | |
| MX2015012540A (es) | Ratón de cadena ligera común. | |
| AR077594A1 (es) | Anticuerpos completamente humanos para btla (atenuante de linfocitos b y t) | |
| BRPI0821682A2 (pt) | Anticorpo monoclonal ou uma sua porção ligante de antígeno, composição farmacêutica, métodos para tratar uma doença imunológica e para produzir o anticorpo monoclonal ou sua porção ligante de antígeno, linhagem de célula isolada, molécula de ácido nucleico isolada, vetor, célula hospedeira, e, processo para identificar anticorpos anti-mif. | |
| JP2014061000A5 (enExample) | ||
| MX353278B (es) | Raton con cadena ligera comun. | |
| MX379533B (es) | Ratones de cadena ligera universal humanizados. | |
| IL198379A (en) | Human antibodies and antibodies that bind sphingosine-1-phosphate, their encoded nucleic acids, and their preparations and methods for treating the disease | |
| NZ602892A (en) | Antibodies that bind human cd27 and uses thereof | |
| CL2007003479A1 (es) | Anticuerpo monoclonal humano anti-cd22 o un fragmento de union a antigeno del mismo; acido nucleico, vector, celula huesped; método de preparacion; composicion; inmunoconjugado; y su uso para inhibir el crecimiento de un tumor o tratar un desorden inflamatorio o autoinmune en un sujeto. |