JP2013518280A5 - - Google Patents
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- Publication number
- JP2013518280A5 JP2013518280A5 JP2012551128A JP2012551128A JP2013518280A5 JP 2013518280 A5 JP2013518280 A5 JP 2013518280A5 JP 2012551128 A JP2012551128 A JP 2012551128A JP 2012551128 A JP2012551128 A JP 2012551128A JP 2013518280 A5 JP2013518280 A5 JP 2013518280A5
- Authority
- JP
- Japan
- Prior art keywords
- polymer
- kinetic parameters
- sensing surface
- biosensor
- speed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 238000000034 method Methods 0.000 claims 16
- 229920000642 polymer Polymers 0.000 claims 8
- 239000012530 fluid Substances 0.000 claims 5
- 238000010494 dissociation reaction Methods 0.000 claims 3
- 230000005593 dissociations Effects 0.000 claims 3
- 239000003446 ligand Substances 0.000 claims 3
- 229920002521 macromolecule Polymers 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 230000027455 binding Effects 0.000 claims 2
- 230000003993 interaction Effects 0.000 claims 2
- 238000012482 interaction analysis Methods 0.000 claims 2
- 238000002198 surface plasmon resonance spectroscopy Methods 0.000 claims 2
- 230000002776 aggregation Effects 0.000 claims 1
- 238000004220 aggregation Methods 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 238000012544 monitoring process Methods 0.000 claims 1
- 239000000178 monomer Substances 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 238000000746 purification Methods 0.000 claims 1
- 230000009870 specific binding Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE1050093 | 2010-01-29 | ||
| SE1050093-2 | 2010-01-29 | ||
| PCT/SE2011/050087 WO2011093782A1 (en) | 2010-01-29 | 2011-01-27 | Method for determination of aggregates |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013518280A JP2013518280A (ja) | 2013-05-20 |
| JP2013518280A5 true JP2013518280A5 (https=) | 2014-03-13 |
| JP5873810B2 JP5873810B2 (ja) | 2016-03-01 |
Family
ID=44319583
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012551128A Active JP5873810B2 (ja) | 2010-01-29 | 2011-01-27 | 凝集体決定法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9470683B2 (https=) |
| EP (1) | EP2529234B1 (https=) |
| JP (1) | JP5873810B2 (https=) |
| WO (1) | WO2011093782A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3100048B1 (en) | 2014-01-29 | 2021-05-05 | Cytiva Sweden AB | Method and system for interaction analysis |
| GB201720162D0 (en) | 2017-12-04 | 2018-01-17 | Univ Oxford Innovation Ltd | Method |
| CN113196055B (zh) | 2018-10-15 | 2025-06-27 | 马克斯·普朗克科学促进协会 | 用于治疗疾病的化合物及其筛选方法 |
| WO2020161173A1 (en) * | 2019-02-05 | 2020-08-13 | Solve Research And Consultancy Ab | A label-free detection method for characterization of the behavior of a component in a liquid |
| CA3127237A1 (en) | 2019-02-08 | 2020-08-13 | Dewpoint Therapeutics, Inc. | Methods of characterizing condensate-associated characteristics of compounds and uses thereof |
| KR20220084047A (ko) | 2019-09-18 | 2022-06-21 | 듀포인트 테라퓨틱스, 인크. | 응축물 관련 특이성에 대한 스크리닝 방법 및 이의 용도 |
| GB201917630D0 (en) | 2019-12-03 | 2020-01-15 | Ge Healthcare Bio Sciences Ab | Method for determination of aggregates |
| JPWO2022270606A1 (https=) * | 2021-06-25 | 2022-12-29 | ||
| WO2022270043A1 (ja) * | 2021-06-25 | 2022-12-29 | コニカミノルタ株式会社 | 解析システム、学習済みモデル生成装置および判別システムならびに解析方法、学習済みモデル生成方法および判別方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9503028D0 (sv) * | 1995-09-01 | 1995-09-01 | Pharmacia Biosensor Ab | Method of analysing chemical and physical interactions at a sensor surface |
| GB0225491D0 (en) * | 2002-11-01 | 2002-12-11 | Farfield Sensors Ltd | Device |
| JP5596255B2 (ja) * | 2003-06-06 | 2014-09-24 | ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ | 分子相互作用パラメータの決定のための方法およびシステム |
| US7373255B2 (en) * | 2003-06-06 | 2008-05-13 | Biacore Ab | Method and system for determination of molecular interaction parameters |
| US20090288479A1 (en) * | 2003-11-17 | 2009-11-26 | Woody Shane C | Standing wave fluidic and biological tools |
| GB0705088D0 (en) * | 2007-03-16 | 2007-04-25 | Akubio Ltd | Improvements in or relating to detection and/or characterisation of aggregates |
| CA2697922A1 (en) * | 2007-08-28 | 2009-03-12 | Biogen Idec Ma Inc. | Compositions that bind multiple epitopes of igf-1r |
| CN101874042B9 (zh) * | 2007-09-26 | 2019-01-01 | 中外制药株式会社 | 利用cdr的氨基酸取代来改变抗体等电点的方法 |
| JP2009078946A (ja) | 2007-09-26 | 2009-04-16 | Fujifilm Corp | コア−シェル型金属酸化物粒子及びその製造方法 |
| WO2011049530A1 (en) | 2009-10-23 | 2011-04-28 | Ge Healthcare Bio-Sciences Ab | Method for determination of macromolecular multimers |
-
2011
- 2011-01-27 US US13/575,197 patent/US9470683B2/en active Active
- 2011-01-27 EP EP11737368.8A patent/EP2529234B1/en active Active
- 2011-01-27 WO PCT/SE2011/050087 patent/WO2011093782A1/en not_active Ceased
- 2011-01-27 JP JP2012551128A patent/JP5873810B2/ja active Active
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