JP2013515474A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2013515474A5 JP2013515474A5 JP2012545436A JP2012545436A JP2013515474A5 JP 2013515474 A5 JP2013515474 A5 JP 2013515474A5 JP 2012545436 A JP2012545436 A JP 2012545436A JP 2012545436 A JP2012545436 A JP 2012545436A JP 2013515474 A5 JP2013515474 A5 JP 2013515474A5
- Authority
- JP
- Japan
- Prior art keywords
- factor
- variant
- nucleic acid
- acid sequence
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0922659.8 | 2009-12-24 | ||
| GBGB0922659.8A GB0922659D0 (en) | 2009-12-24 | 2009-12-24 | Factor H |
| PCT/GB2010/002334 WO2011077102A1 (en) | 2009-12-24 | 2010-12-23 | Recombinant factor h and variants and conjugates thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013515474A JP2013515474A (ja) | 2013-05-09 |
| JP2013515474A5 true JP2013515474A5 (https=) | 2014-02-20 |
Family
ID=41716988
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012545436A Abandoned JP2013515474A (ja) | 2009-12-24 | 2010-12-23 | 組換え体ｈ因子ならびにそのバリアントおよびコンジュゲート |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US8889374B2 (https=) |
| EP (1) | EP2516464B1 (https=) |
| JP (1) | JP2013515474A (https=) |
| GB (1) | GB0922659D0 (https=) |
| WO (1) | WO2011077102A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0922659D0 (en) | 2009-12-24 | 2010-02-10 | Univ Edinburgh | Factor H |
| FR2981661B1 (fr) * | 2011-10-25 | 2015-06-19 | Lfb Biotechnologies | Procede de preparation du facteur h humain |
| FR3015484A1 (fr) * | 2013-12-20 | 2015-06-26 | Lab Francais Du Fractionnement | Proteines recombinantes possedant une activite de facteur h |
| FR3038517B1 (fr) | 2015-07-06 | 2020-02-28 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Utilisation de fragments fc modifies en immunotherapie |
| CN108291216B (zh) | 2015-09-24 | 2022-09-16 | 宾夕法尼亚州大学信托人 | 用于治疗补体介导的疾病的组合物和方法 |
| US10975131B2 (en) * | 2015-10-27 | 2021-04-13 | University Of Massachusetts | Factor H-Fc immunotheraphy |
| GB201706808D0 (en) | 2017-04-28 | 2017-06-14 | Univ Newcastle | Modified complement proteins and uses thereof |
| GB201800620D0 (en) | 2018-01-15 | 2018-02-28 | Univ Manchester | C3b Binding Polypeptide |
| US20210338838A1 (en) * | 2018-07-20 | 2021-11-04 | University Of Utah Research Foundation | Gene therapy for macular degeneration |
| JP7222075B2 (ja) * | 2018-09-13 | 2023-02-14 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | Ｃ３糸球体症のモデルとしての補体因子ｈ遺伝子ノックアウトラット |
| CA3182800A1 (en) | 2020-06-14 | 2021-12-23 | Vertex Pharmaceuticals Inc. | Complement factor i-related compositions and methods |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7037504B2 (en) | 2001-10-23 | 2006-05-02 | Waratah Pharmaceuticals, Inc. | Epidermal growth factor protein and gene, and methods of use therefor |
| EP1336618A1 (en) | 2002-02-15 | 2003-08-20 | HANS-KNÖLL-INSTITUT FÜR NATURSTOFF-FORSCHUNG e.V. | Porcine complement regulator factor H and its use |
| US7745389B2 (en) | 2005-02-14 | 2010-06-29 | University Of Iowa Research Foundation | Methods for treatment of age-related macular degeneration |
| US20090118163A1 (en) | 2005-09-19 | 2009-05-07 | Peter Gronski | Factor H for the Treatment of Chronic Nephropathies and Production thereof |
| US7759304B2 (en) * | 2006-06-21 | 2010-07-20 | Regents Of The University Of Colorado | Targeting complement factor H for treatment of diseases |
| US20110159018A1 (en) | 2007-05-03 | 2011-06-30 | Medizinische Universitat Innsbruck | Complement factor h-derived short consensus repeat-antibody constructs |
| WO2008139496A1 (en) | 2007-05-16 | 2008-11-20 | Bigtec Private Limited | Recombinant human insulin and a method thereof |
| GB0922659D0 (en) | 2009-12-24 | 2010-02-10 | Univ Edinburgh | Factor H |
| US20130011857A1 (en) | 2010-02-12 | 2013-01-10 | Cemm Forschungszentrum Fur Molekulare Medizin Gmbh | Complement factor h for oxidative stress disease conditions |
| US9540626B2 (en) | 2012-03-19 | 2017-01-10 | The Trustees Of The University Of Pennsylvania | Regulator of complement activation and uses thereof |
-
2009
- 2009-12-24 GB GBGB0922659.8A patent/GB0922659D0/en not_active Ceased
-
2010
- 2010-12-23 US US13/518,614 patent/US8889374B2/en active Active
- 2010-12-23 EP EP10803266.5A patent/EP2516464B1/en not_active Not-in-force
- 2010-12-23 WO PCT/GB2010/002334 patent/WO2011077102A1/en not_active Ceased
- 2010-12-23 JP JP2012545436A patent/JP2013515474A/ja not_active Abandoned
-
2014
- 2014-11-14 US US14/541,834 patent/US20150139975A1/en not_active Abandoned
-
2017
- 2017-04-10 US US15/483,814 patent/US10378005B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2013515474A5 (https=) | ||
| NZ598351A (en) | Il-17 binding compounds and medical uses thereof | |
| JP2019530463A5 (https=) | ||
| JP2012522529A5 (https=) | ||
| JP2010534486A5 (https=) | ||
| JP2009529856A5 (https=) | ||
| NZ602943A (en) | Modified binding proteins inhibiting the vegf-a receptor interaction | |
| JP2012525844A5 (https=) | ||
| He et al. | Identification of SCARA3, SCARA5 and MARCO of class A scavenger receptor-like family in Pseudosciaena crocea | |
| JP2012082206A5 (https=) | ||
| MX2012015142A (es) | Polipeptidos que tiene actividad beta-glucosidasa y usos del mismo. | |
| NZ603623A (en) | Tcr complex immunotherapeutics | |
| JP2011004753A5 (https=) | ||
| JP2019506166A5 (https=) | ||
| WO2012077950A3 (ko) | 히알루론산-단백질 컨쥬게이트 및 이의 제조 방법 | |
| IN2012DN03368A (https=) | ||
| JP2018537087A5 (https=) | ||
| JP2014514921A5 (https=) | ||
| WO2013186563A3 (en) | Factor viii sequences | |
| EA201300060A1 (ru) | Полипептид, обладающий или содействующий активности деградации углеводного материала, и его применение | |
| JP2006149365A5 (https=) | ||
| HRP20192080T1 (hr) | Terapeutske fuzije nukleaza-albumine i postupci | |
| JP2013530689A5 (https=) | ||
| MX2012005864A (es) | Proteinas de enlace al antígeno anti-orai 1 y usos de las mismas. | |
| KR20200123132A (ko) | 융합 단백질 |