JP2013515474A5 - - Google Patents
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- Publication number
- JP2013515474A5 JP2013515474A5 JP2012545436A JP2012545436A JP2013515474A5 JP 2013515474 A5 JP2013515474 A5 JP 2013515474A5 JP 2012545436 A JP2012545436 A JP 2012545436A JP 2012545436 A JP2012545436 A JP 2012545436A JP 2013515474 A5 JP2013515474 A5 JP 2013515474A5
- Authority
- JP
- Japan
- Prior art keywords
- factor
- variant
- nucleic acid
- acid sequence
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0922659.8 | 2009-12-24 | ||
| GBGB0922659.8A GB0922659D0 (en) | 2009-12-24 | 2009-12-24 | Factor H |
| PCT/GB2010/002334 WO2011077102A1 (en) | 2009-12-24 | 2010-12-23 | Recombinant factor h and variants and conjugates thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013515474A JP2013515474A (ja) | 2013-05-09 |
| JP2013515474A5 true JP2013515474A5 (cg-RX-API-DMAC7.html) | 2014-02-20 |
Family
ID=41716988
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012545436A Abandoned JP2013515474A (ja) | 2009-12-24 | 2010-12-23 | 組換え体ｈ因子ならびにそのバリアントおよびコンジュゲート |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US8889374B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2516464B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2013515474A (cg-RX-API-DMAC7.html) |
| GB (1) | GB0922659D0 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2011077102A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0922659D0 (en) | 2009-12-24 | 2010-02-10 | Univ Edinburgh | Factor H |
| FR2981661B1 (fr) * | 2011-10-25 | 2015-06-19 | Lfb Biotechnologies | Procede de preparation du facteur h humain |
| FR3015484A1 (fr) * | 2013-12-20 | 2015-06-26 | Lab Francais Du Fractionnement | Proteines recombinantes possedant une activite de facteur h |
| FR3038517B1 (fr) | 2015-07-06 | 2020-02-28 | Laboratoire Francais Du Fractionnement Et Des Biotechnologies | Utilisation de fragments fc modifies en immunotherapie |
| CN108291216B (zh) * | 2015-09-24 | 2022-09-16 | 宾夕法尼亚州大学信托人 | 用于治疗补体介导的疾病的组合物和方法 |
| WO2017075189A1 (en) * | 2015-10-27 | 2017-05-04 | University Of Massachusetts | Factor h-fc immunotherapy |
| GB201706808D0 (en) | 2017-04-28 | 2017-06-14 | Univ Newcastle | Modified complement proteins and uses thereof |
| GB201800620D0 (en) | 2018-01-15 | 2018-02-28 | Univ Manchester | C3b Binding Polypeptide |
| CA3106838A1 (en) * | 2018-07-20 | 2020-01-23 | University Of Utah Research Foundation | Gene therapy for macular degeneration |
| US20220053741A1 (en) * | 2018-09-13 | 2022-02-24 | Regeneron Pharmaceuticals, Inc. | Complement Factor H Gene Knockout Rat as a Model of C3 Glomerulopathy |
| IL299048A (en) | 2020-06-14 | 2023-02-01 | Vertex Pharma | Variants of complement factor - 1 fusion structures and preparations containing them and their uses |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7037504B2 (en) | 2001-10-23 | 2006-05-02 | Waratah Pharmaceuticals, Inc. | Epidermal growth factor protein and gene, and methods of use therefor |
| EP1336618A1 (en) | 2002-02-15 | 2003-08-20 | HANS-KNÖLL-INSTITUT FÜR NATURSTOFF-FORSCHUNG e.V. | Porcine complement regulator factor H and its use |
| NZ608860A (en) | 2005-02-14 | 2014-10-31 | Univ Iowa Res Found | Methods and reagents for treatment and diagnosis of age-related macular degeneration |
| CA2627264A1 (en) | 2005-09-19 | 2007-04-12 | Csl Behring Gmbh | Factor h for the treatment of chronic nephropathies and production thereof |
| PL2044111T3 (pl) * | 2006-06-21 | 2015-02-27 | Musc Found For Res Dev | Celowanie czynnika H dopełniacza do leczenia chorób |
| EP2152736B1 (en) | 2007-05-03 | 2017-07-05 | Lysomab GmbH | Complement factor h-derived short consensus repeat-antibody constructs |
| WO2008139496A1 (en) | 2007-05-16 | 2008-11-20 | Bigtec Private Limited | Recombinant human insulin and a method thereof |
| GB0922659D0 (en) | 2009-12-24 | 2010-02-10 | Univ Edinburgh | Factor H |
| EP2533797A1 (en) | 2010-02-12 | 2012-12-19 | CeMM Forschungszentrum für Molekulare Medizin GmbH | Complement factor h for oxidative stress disease conditions |
| US9540626B2 (en) | 2012-03-19 | 2017-01-10 | The Trustees Of The University Of Pennsylvania | Regulator of complement activation and uses thereof |
-
2009
- 2009-12-24 GB GBGB0922659.8A patent/GB0922659D0/en not_active Ceased
-
2010
- 2010-12-23 US US13/518,614 patent/US8889374B2/en active Active
- 2010-12-23 EP EP10803266.5A patent/EP2516464B1/en not_active Not-in-force
- 2010-12-23 JP JP2012545436A patent/JP2013515474A/ja not_active Abandoned
- 2010-12-23 WO PCT/GB2010/002334 patent/WO2011077102A1/en not_active Ceased
-
2014
- 2014-11-14 US US14/541,834 patent/US20150139975A1/en not_active Abandoned
-
2017
- 2017-04-10 US US15/483,814 patent/US10378005B2/en not_active Expired - Fee Related
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