JP2013507159A - ロックアウト機能を備えた薬剤注射デバイス - Google Patents
ロックアウト機能を備えた薬剤注射デバイス Download PDFInfo
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- JP2013507159A JP2013507159A JP2012532618A JP2012532618A JP2013507159A JP 2013507159 A JP2013507159 A JP 2013507159A JP 2012532618 A JP2012532618 A JP 2012532618A JP 2012532618 A JP2012532618 A JP 2012532618A JP 2013507159 A JP2013507159 A JP 2013507159A
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- injection system
- safety injection
- lock
- cap
- dose
- Prior art date
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- 238000002347 injection Methods 0.000 title claims abstract description 59
- 239000007924 injection Substances 0.000 title claims abstract description 59
- 239000003814 drug Substances 0.000 title abstract description 18
- 229940079593 drug Drugs 0.000 title abstract description 14
- 230000000007 visual effect Effects 0.000 claims description 4
- 238000004891 communication Methods 0.000 claims description 2
- 238000012360 testing method Methods 0.000 claims description 2
- 230000007246 mechanism Effects 0.000 description 27
- 238000012377 drug delivery Methods 0.000 description 23
- 238000010168 coupling process Methods 0.000 description 6
- 230000008878 coupling Effects 0.000 description 5
- 238000005859 coupling reaction Methods 0.000 description 5
- 230000036541 health Effects 0.000 description 4
- 238000013461 design Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 230000001681 protective effect Effects 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 101000976075 Homo sapiens Insulin Proteins 0.000 description 1
- 102000002265 Human Growth Hormone Human genes 0.000 description 1
- 108010000521 Human Growth Hormone Proteins 0.000 description 1
- 239000000854 Human Growth Hormone Substances 0.000 description 1
- 102000004877 Insulin Human genes 0.000 description 1
- 108010092217 Long-Acting Insulin Proteins 0.000 description 1
- 229940100066 Long-acting insulin Drugs 0.000 description 1
- 108010026951 Short-Acting Insulin Proteins 0.000 description 1
- 229940123958 Short-acting insulin Drugs 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 229940125396 insulin Drugs 0.000 description 1
- 239000004026 insulin derivative Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000002547 new drug Substances 0.000 description 1
- 230000002028 premature Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000012549 training Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31525—Dosing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2403—Ampoule inserted into the ampoule holder
- A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2485—Ampoule holder connected to rest of syringe
- A61M2005/2488—Ampoule holder connected to rest of syringe via rotation, e.g. threads or bayonet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2485—Ampoule holder connected to rest of syringe
- A61M2005/2492—Ampoule holder connected to rest of syringe via snap connection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3125—Details specific display means, e.g. to indicate dose setting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/582—Means for facilitating use, e.g. by people with impaired vision by tactile feedback
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R31/00—Arrangements for testing electric properties; Arrangements for locating electric faults; Arrangements for electrical testing characterised by what is being tested not provided for elsewhere
- G01R31/36—Arrangements for testing, measuring or monitoring the electrical condition of accumulators or electric batteries, e.g. capacity or state of charge [SoC]
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- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
【選択図】図1
Description
Claims (16)
- 針を受け入れるための遠位端、及び用量を設定するための近位端を有する反復用量送達モジュール;
用量送達モジュールの遠位端上で針を覆うように構成された取り外し可能なキャップ;及び
キャップ及び反復用量送達モジュールに機能的に連結した時限錠;
を含んでなる、安全注射システム。 - 時限錠は、使用者が、反復用量送達モジュール上に用量を設定するためキャップを取り外すことを阻止するように構成される、請求項1に記載の安全注射システム。
- 時限錠は時間制御される、請求項1又は2に記載の安全注射システム。
- 時限錠は設定可能である、請求項1〜3のいずれか1項に記載の安全注射システム。
- 時限錠はコントローラにより開放され、及び閉鎖される、請求項1〜4のいずれか1項に記載の安全注射システム。
- コントローラは反復用量送達モジュールの一部又はキャップの一部である、請求項6に記載の安全注射システム。
- コントローラは信号を電子回路から受信するように構成される、請求項5又は6に記載の安全注射システム。
- 信号は有線又は無線で伝達され得る、請求項7に記載の安全注射システム。
- 電子回路は、キャップ、反復用量送達モジュール、パーソナルコンピュータ、リモートコンピュータ、リモートサーバ、又はこれらの組合せの一部である、請求項7又は8に記載の安全注射システム。
- コントローラはプログラム化可能である、請求項7〜9のいずれか1項に記載の安全注射システム。
- 更に、コントローラと通信する警告サブシステムを含む、請求項7〜9のいずれか1項に記載の安全注射システム。
- 警告サブシステムは、安全注射デバイスの使用者に聴覚的、視覚的又は触覚的、又は聴覚的/視覚的、聴覚的/触覚的又は視覚的/触覚的な組合せの信号を提供するように構成される、請求項11に記載の安全注射システム。
- コントローラは、安全注射システムの使用者の生理学的特性を監視し、又は試験するように構成された分析デバイスと通信する、請求項7〜12のいずれか1項に記載の安全注射システム。
- ロックは、使用者が、一つ又はそれ以上の所定の信号をコントローラに入力した後、デバイスをロックから開放するのを可能にするオーバーライド機能を有する、請求項7〜13のいずれか1項に記載の安全注射システム。
- 安全注射システムは、設定時間又は設定可能時間の後、時限錠を恒久的に閉鎖するように構成された、請求項1〜14のいずれか1項に記載の安全注射システム。
- 時限錠を作動させるためのエネルギ供給源を備えた、請求項1〜15のいずれか1項に記載の安全注射システムであって、ここで、安全注射システムは、エネルギ供給源に残留したエネルギが、設定閾値を下回るとき、時限錠を開放するように構成される、上記安全注射システム。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP09172508 | 2009-10-08 | ||
EP09172508.5 | 2009-10-08 | ||
PCT/EP2010/065097 WO2011042540A1 (en) | 2009-10-08 | 2010-10-08 | Medicament injection device with lockout feature |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2013507159A true JP2013507159A (ja) | 2013-03-04 |
JP5706900B2 JP5706900B2 (ja) | 2015-04-22 |
Family
ID=42027759
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012532618A Expired - Fee Related JP5706900B2 (ja) | 2009-10-08 | 2010-10-08 | ロックアウト機能を備えた薬剤注射デバイス |
Country Status (5)
Country | Link |
---|---|
US (1) | US8882722B2 (ja) |
EP (1) | EP2485787A1 (ja) |
JP (1) | JP5706900B2 (ja) |
CA (1) | CA2776870A1 (ja) |
WO (1) | WO2011042540A1 (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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JP2016527938A (ja) * | 2013-06-28 | 2016-09-15 | アニマス・コーポレイション | 安全保護装置を備える薬物注入装置 |
JP2020501657A (ja) * | 2016-12-08 | 2020-01-23 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 注射デバイス |
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FI1850892T4 (fi) | 2005-01-24 | 2023-08-31 | Neula-avusteinen esitäytetyn ruiskun omaava suihkuinjektori | |
WO2007131025A1 (en) | 2006-05-03 | 2007-11-15 | Antares Pharma, Inc. | Injector with adjustable dosing |
US8251947B2 (en) | 2006-05-03 | 2012-08-28 | Antares Pharma, Inc. | Two-stage reconstituting injector |
ES2548447T3 (es) | 2008-03-10 | 2015-10-16 | Antares Pharma, Inc. | Dispositivo de seguridad para inyector |
JP5611208B2 (ja) | 2008-08-05 | 2014-10-22 | アンタレス・ファーマ・インコーポレーテッド | 多数回服用量の注射装置 |
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- 2010-10-08 US US13/500,806 patent/US8882722B2/en active Active
- 2010-10-08 CA CA2776870A patent/CA2776870A1/en not_active Abandoned
- 2010-10-08 WO PCT/EP2010/065097 patent/WO2011042540A1/en active Application Filing
- 2010-10-08 JP JP2012532618A patent/JP5706900B2/ja not_active Expired - Fee Related
- 2010-10-08 EP EP10762698A patent/EP2485787A1/en not_active Withdrawn
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2016527938A (ja) * | 2013-06-28 | 2016-09-15 | アニマス・コーポレイション | 安全保護装置を備える薬物注入装置 |
JP2020501657A (ja) * | 2016-12-08 | 2020-01-23 | サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 注射デバイス |
JP7069167B2 (ja) | 2016-12-08 | 2022-05-17 | サノフィ-アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング | 注射デバイス |
US11338094B2 (en) | 2016-12-08 | 2022-05-24 | Sanofi-Aventis Deutschland Gmbh | Injection device |
US11998724B2 (en) | 2016-12-08 | 2024-06-04 | Sanofi-Aventis Deutschland Gmbh | Injection device |
Also Published As
Publication number | Publication date |
---|---|
WO2011042540A1 (en) | 2011-04-14 |
CA2776870A1 (en) | 2011-04-14 |
US8882722B2 (en) | 2014-11-11 |
US20130012885A1 (en) | 2013-01-10 |
EP2485787A1 (en) | 2012-08-15 |
JP5706900B2 (ja) | 2015-04-22 |
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