JP2013501722A5 - - Google Patents
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- Publication number
- JP2013501722A5 JP2013501722A5 JP2012523949A JP2012523949A JP2013501722A5 JP 2013501722 A5 JP2013501722 A5 JP 2013501722A5 JP 2012523949 A JP2012523949 A JP 2012523949A JP 2012523949 A JP2012523949 A JP 2012523949A JP 2013501722 A5 JP2013501722 A5 JP 2013501722A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- compound
- subject
- formulated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 22
- 150000001875 compounds Chemical class 0.000 claims 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 6
- 102000001307 androgen receptors Human genes 0.000 claims 4
- 108010080146 androgen receptors Proteins 0.000 claims 4
- 201000010099 disease Diseases 0.000 claims 4
- 230000001404 mediated effect Effects 0.000 claims 4
- 206010060862 Prostate cancer Diseases 0.000 claims 3
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 3
- 239000002775 capsule Substances 0.000 claims 2
- 208000035475 disorder Diseases 0.000 claims 2
- 201000004384 Alopecia Diseases 0.000 claims 1
- 208000000103 Anorexia Nervosa Diseases 0.000 claims 1
- 206010004446 Benign prostatic hyperplasia Diseases 0.000 claims 1
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 206010020112 Hirsutism Diseases 0.000 claims 1
- 206010054834 Hypergonadism Diseases 0.000 claims 1
- 208000004403 Prostatic Hyperplasia Diseases 0.000 claims 1
- 229920002472 Starch Polymers 0.000 claims 1
- 231100000360 alopecia Toxicity 0.000 claims 1
- 239000011230 binding agent Substances 0.000 claims 1
- 239000006071 cream Substances 0.000 claims 1
- 239000007884 disintegrant Substances 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 239000000945 filler Substances 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- -1 glidants Substances 0.000 claims 1
- 239000006210 lotion Substances 0.000 claims 1
- 239000000314 lubricant Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000003921 oil Substances 0.000 claims 1
- 239000002674 ointment Substances 0.000 claims 1
- 239000006072 paste Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 239000008107 starch Substances 0.000 claims 1
- 235000019698 starch Nutrition 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 239000003826 tablet Substances 0.000 claims 1
- 239000002966 varnish Substances 0.000 claims 1
- 239000001993 wax Substances 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23225709P | 2009-08-07 | 2009-08-07 | |
| US61/232,257 | 2009-08-07 | ||
| US26126509P | 2009-11-13 | 2009-11-13 | |
| US61/261,265 | 2009-11-13 | ||
| PCT/US2010/044570 WO2011017534A2 (en) | 2009-08-07 | 2010-08-05 | Treatment of prostate cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015221564A Division JP2016074687A (ja) | 2009-08-07 | 2015-11-11 | 前立腺癌の処置 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013501722A JP2013501722A (ja) | 2013-01-17 |
| JP2013501722A5 true JP2013501722A5 (https=) | 2013-09-19 |
Family
ID=43535282
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012523949A Pending JP2013501722A (ja) | 2009-08-07 | 2010-08-05 | 前立腺癌の処置 |
| JP2015221564A Pending JP2016074687A (ja) | 2009-08-07 | 2015-11-11 | 前立腺癌の処置 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015221564A Pending JP2016074687A (ja) | 2009-08-07 | 2015-11-11 | 前立腺癌の処置 |
Country Status (8)
| Country | Link |
|---|---|
| US (5) | US8791094B2 (https=) |
| EP (1) | EP2461814A4 (https=) |
| JP (2) | JP2013501722A (https=) |
| KR (1) | KR20120056267A (https=) |
| AU (1) | AU2010279398A1 (https=) |
| BR (1) | BR112012002797A2 (https=) |
| CA (1) | CA2770092A1 (https=) |
| WO (1) | WO2011017534A2 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100048913A1 (en) | 2008-03-14 | 2010-02-25 | Angela Brodie | Novel C-17-Heteroaryl Steroidal CYP17 Inhibitors/Antiandrogens;Synthesis In Vitro Biological Activities, Pharmacokinetics and Antitumor Activity |
| US8785423B2 (en) * | 2008-04-14 | 2014-07-22 | University Of Maryland, Baltimore | Compositions and methods of inducing endoplasmic reticulum stress response for the treatment of cell proliferative diseases |
| CN102686600A (zh) | 2009-02-05 | 2012-09-19 | 托凯药业股份有限公司 | 甾体cyp17抑制剂/抗雄激素物质的新型药物前体 |
| WO2010149755A1 (en) | 2009-06-26 | 2010-12-29 | Novartis Ag | 1, 3-disubstituted imidazolidin-2-one derivatives as inhibitors of cyp 17 |
| CA2770092A1 (en) | 2009-08-07 | 2011-02-10 | Tokai Pharmaceuticals, Inc. | Treatment of prostate cancer |
| US9029399B2 (en) | 2011-04-28 | 2015-05-12 | Novartis Ag | 17α-hydroxylase/C17,20-lyase inhibitors |
| CN103813794A (zh) * | 2011-07-18 | 2014-05-21 | 拓凯制药公司 | 用于治疗前列腺癌的新型组合物及方法 |
| WO2013022821A1 (en) * | 2011-08-05 | 2013-02-14 | Gen-Probe Incorporated | Antiandrogen therapy monitoring methods and compositions |
| WO2013071177A1 (en) * | 2011-11-10 | 2013-05-16 | Tokai Pharmaceuticals, Inc. | Methods and compositions for inhibition of androgen receptor activity |
| RU2015137617A (ru) | 2013-03-14 | 2017-04-18 | Юниверсити Оф Мэриленд, Балтимор Офис Оф Текнолоджи Трансфер | Агенты, подавляющие андрогенные рецепторы, и их применение |
| CN105636594A (zh) | 2013-08-12 | 2016-06-01 | 托凯药业股份有限公司 | 使用雄激素靶向疗法用于治疗肿瘤性疾病的生物标记物 |
| WO2015170336A1 (en) | 2014-05-09 | 2015-11-12 | Council Of Scientific & Industrial Research | 16α-HETEROARYL PREGNENOLONE ACETATE AND A PROCESS FOR PREPARATION THEREOF |
| CN105732759A (zh) * | 2015-01-29 | 2016-07-06 | 苏州晶云药物科技有限公司 | (3β)-17-(1H-苯并咪唑-1-基)雄甾-5，16-二烯-3-醇的盐及其制备方法 |
| ITUA20164043A1 (it) * | 2016-06-01 | 2017-12-01 | Ind Chimica Srl | Processo per la preparazione di 3β-idrossi-17-(1H-benzimidazol-1-il)androsta-5,16-diene |
| WO2017208132A1 (en) * | 2016-06-01 | 2017-12-07 | Industriale Chimica S.R.L. | Process for the preparation of galeterone |
| EP3807889A1 (en) * | 2018-06-14 | 2021-04-21 | AstraZeneca UK Limited | Methods for treating and preventing symptoms of asthma with a corticosteroid pharmaceutical composition |
| US12337004B2 (en) * | 2019-04-27 | 2025-06-24 | Health Research, Inc. | Coumarin-modified androgens for the treatment of prostate cancer |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH621803A5 (https=) | 1974-08-08 | 1981-02-27 | Siphar Sa | |
| US5604213A (en) | 1992-03-31 | 1997-02-18 | British Technology Group Limited | 17-substituted steroids useful in cancer treatment |
| JPH08509617A (ja) | 1993-04-30 | 1996-10-15 | パシフィック・ノースウエスト・リサーチ・ファウンデーション | 細胞酸化還元電位と癌危険性とのインジケータとしてのｄｎａプロフィル |
| US5994335A (en) | 1997-10-17 | 1999-11-30 | The University Of Maryland, Baltimore | 17-azolyl steroids useful as androgen synthesis inhibitors |
| US20030054053A1 (en) | 2001-09-20 | 2003-03-20 | Charles Young | Methods and compositions for inhibiting the proliferation of prostate cancer cells |
| WO2005014023A1 (en) | 2003-07-29 | 2005-02-17 | Dompe' Pha.R.Ma S.P.A. | Pharmaceutical combination of g-csf and plgf useful for blood stem cell |
| JP4585201B2 (ja) * | 2004-01-23 | 2010-11-24 | 丸善製薬株式会社 | アンドロゲン受容体結合阻害剤、養毛剤、皮脂分泌抑制剤及び前立腺肥大抑制剤 |
| AU2006218711B2 (en) | 2005-03-02 | 2010-11-11 | University Of Maryland, Baltimore | Novel C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens: synthesis, in vitro biological activities, pharmacokinetics and antitumor activity |
| WO2008154382A1 (en) * | 2007-06-06 | 2008-12-18 | University Of Maryland, Baltimore | Hdac inhibitors and hormone targeted drugs for the treatment of cancer |
| US20100048913A1 (en) | 2008-03-14 | 2010-02-25 | Angela Brodie | Novel C-17-Heteroaryl Steroidal CYP17 Inhibitors/Antiandrogens;Synthesis In Vitro Biological Activities, Pharmacokinetics and Antitumor Activity |
| CA2770092A1 (en) | 2009-08-07 | 2011-02-10 | Tokai Pharmaceuticals, Inc. | Treatment of prostate cancer |
-
2010
- 2010-08-05 CA CA2770092A patent/CA2770092A1/en not_active Abandoned
- 2010-08-05 AU AU2010279398A patent/AU2010279398A1/en not_active Abandoned
- 2010-08-05 JP JP2012523949A patent/JP2013501722A/ja active Pending
- 2010-08-05 BR BR112012002797A patent/BR112012002797A2/pt not_active IP Right Cessation
- 2010-08-05 EP EP10807167A patent/EP2461814A4/en not_active Withdrawn
- 2010-08-05 US US12/851,070 patent/US8791094B2/en not_active Expired - Fee Related
- 2010-08-05 WO PCT/US2010/044570 patent/WO2011017534A2/en not_active Ceased
- 2010-08-05 KR KR1020127006009A patent/KR20120056267A/ko not_active Ceased
-
2014
- 2014-06-24 US US14/313,894 patent/US9156878B2/en not_active Expired - Fee Related
-
2015
- 2015-03-02 US US14/635,415 patent/US20150203528A1/en not_active Abandoned
- 2015-03-02 US US14/635,469 patent/US20150166599A1/en not_active Abandoned
- 2015-11-11 JP JP2015221564A patent/JP2016074687A/ja active Pending
-
2017
- 2017-02-23 US US15/440,623 patent/US20170157148A1/en not_active Abandoned
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