JP2013189417A - Composition of liquid external preparation for skin - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a composition of liquid external preparation for skin, suppressing stickiness and creak caused by compounding a tranexamic acid, causing no discoloration due to time lapse, having freshness and excellent in adaptability.SOLUTION: A composition of an oil-in-water type emulsified liquid external preparation for skin comprises (A) a nonionic surfactant of an HLB of 5-9, (B) a polyoxypropylene-polyoxyethylene copolymer alkyl ether, (C) dimethylpolysiloxane, (D) ethanol, (E) an anionic surfactant and (F) tranexamic acid, and having a 20-600 nm emulsified particle diameter.

Description

  The present invention relates to an oil-in-water liquid external preparation for skin. More specifically, the present invention relates to an oil-in-water type finely emulsified skin external preparation composition having a feeling of use that is not sticky and is fresh and familiar, while incorporating tranexamic acid or a derivative thereof.

  Tranexamic acids have anti-plasmin action and are incorporated into various cosmetics as an active ingredient for improving rough skin and whitening. Synergistic effects and new effects are also found by combining tranexamic acids with other substances. ing.

  However, cosmetics formulated with tranexamic acids, especially low-viscosity cosmetics such as lotions, have the problem of causing stickiness and creaking due to the formulation of tranexamic acid. In Patent Document 1, a predetermined amount of xanthan gum is formulated. It is described that stickiness and squeak are suppressed by doing. However, although stickiness and creaking are suppressed by the blending of xanthan gum, slimming occurs and a refreshing feel may not be obtained.

  On the other hand, it is known that the feeling of use is improved by blending an oil such as silicone oil. However, in order to obtain a transparent or translucent emulsified cosmetic by stably blending silicone oil into the system, a special treatment that gives a strong shearing force is required, and an oil-in-water emulsion is inferior in water resistance. There was also a problem.

Patent Document 2 describes that emulsified cosmetics that are transparent or translucent and excellent in feel can be easily obtained by combining a silicone oil having a specific viscosity and a silicone surfactant in combination. Patent Document 3 discloses an oil-in-water fine emulsion external preparation containing a predetermined amount of HLB 5-9 nonionic surfactant, polyoxypropylene / polyoxyethylene copolymer alkyl ether, oil, water, and ethanol. It is said that a refreshing feeling at the time of application is obtained and water resistance is also excellent.
However, Patent Documents 2 and 3 do not suggest that a problem of usability such as stickiness occurs when tranexamic acid is blended, and what these bases are against stickiness caused by tranexamic acid. It was unclear whether it would work.

Japanese Patent No. 4726151 Japanese Patent No. 3484300 JP 2008-1000093 A

  Accordingly, an object of the present invention is to provide a liquid skin external preparation composition that not only suppresses stickiness and creaking caused by the addition of tranexamic acids but also does not cause discoloration over time and is fresh and familiar.

  In order to solve the above problems, the present inventors have conducted intensive research, and as a result, by adding a predetermined amount of an anionic surfactant to the oil-in-water type fine emulsion composition, stickiness caused by tranexamic acids can be reduced. It has been found that a liquid skin external preparation composition can be obtained that can suppress squeaking, has no sliminess, is excellent in penetrating feeling, and is also excellent in high-temperature stability, and has completed the present invention.

That is, the present invention
(A) a nonionic surfactant of HLB 5-9,
(B) a polyoxypropylene / polyoxyethylene copolymer alkyl ether;
(C) dimethylpolysiloxane;
(D) ethanol,
(E) an anionic surfactant of less than 0.1% by mass;
An oil-in-water emulsified liquid skin external preparation composition comprising (F) tranexamic acid and having an emulsified particle diameter of 20 to 600 nm is provided.

  Even if the oil-in-water emulsified liquid skin external preparation composition of the present invention contains tranexamic acids, stickiness and creaking caused by it are suppressed, a slimy and fresh feel is obtained, and it has excellent stability and No discoloration occurs.

In the composition of the present invention which is an oil-in-water emulsion, an HLB 5-9 nonionic surfactant (component A) usually used for a water-in-oil emulsion is blended as an essential component.
Examples of nonionic surfactants of HLB 5-9 include polyoxyethylene fatty acid glyceryl, polyglycerin fatty acid glyceryl, mono fatty acid glyceryl, polyoxyethylene-methylpolysiloxane copolymer, fatty acid polyoxyethylene sorbitan, polyoxyethylene Examples include alkyl ethers, alkylated polysaccharides, alkyl glucosides, and sucrose fatty acid esters. In addition, when using 2 or more types of nonionic surfactants, the weighted average value of HLB calculated from each HLB value of the blended nonionic surfactant and the weight ratio thereof is 5 to 9. In this case, each nonionic surfactant does not need to be in the range of HLB5 to 9 alone. If the HLB of the nonionic surfactant is less than 5, an oil-in-water fine emulsion may not be obtained. Conversely, if the HLB exceeds 9, phase inversion to the water-in-oil type occurs. In some cases, the penetrating feeling and water resistance after application may not be obtained.

  Although the compounding quantity of the nonionic surfactant of HLB5-9 in the composition of this invention is not specifically limited, It is preferable that it is 0.1-5 mass%. Depending on the amount of oil in the composition, if the amount of the nonionic surfactant is less than 0.1% by mass, an oil-in-water fine emulsion may not be obtained. If it exceeds the range, it may not be preferable from the viewpoint of safety.

  The polyoxypropylene / polyoxyethylene copolymer alkyl ether (component B) used in the present invention is not particularly limited, but is a polyoxypropylene / polyoxyethylene copolymer dialkyl ether such as polyoxypropylene. Examples thereof include propylene / polyoxyethylene copolymer dimethyl ether, polyoxypropylene / polyoxyethylene copolymer diethyl ether, and the like, and a random copolymer is particularly preferable. The polyoxypropylene / polyoxyethylene random copolymer alkyl ether can be produced by a known method. For example, it can be obtained by addition-polymerizing ethylene oxide and propylene oxide to a compound having a hydroxyl group and then ether-reacting an alkyl halide in the presence of an alkali catalyst.

In addition, in the polyoxypropylene / polyoxyethylene copolymer alkyl ether used in the present invention, the nonionic property of the HLB 5-9 in an aqueous solution of the polyoxypropylene / polyoxyethylene copolymer alkyl ether (component B) is used. The critical micelle concentration (cmc) of the surfactant (component A) is preferably higher than the critical micelle concentration of the nonionic surfactant in water not containing the component B. By selecting a combination of component A and component B that satisfies such conditions, the stability of the fine emulsion is further improved.
In addition, the average addition mole number of oxypropylene is 1 to 10 and the average addition of oxyethylene chain, although it varies depending on the type of nonionic surfactant (component A) of HLB 5-9 and the following oil component (component C ′). The number of moles is preferably 9 to 100, and the ratio [POE / (POE + POP)] of the average added mole number of oxyethylene to the total of the average added mole numbers of oxyethylene and oxypropylene is preferably 0.5 to 0.9. Here, POE refers to polyoxyethylene and POP refers to polyoxypropylene. The terminal alkyl group is particularly preferably a methyl group.

  Although the compounding quantity of the polyoxypropylene polyoxyethylene copolymer alkyl ether used for this invention is not specifically limited, It is preferable to set it as 0.1-10 mass%. If the blending amount is less than 0.1% by mass, the region of the stable oil-in-water microemulsion phase becomes very narrow, and the preparation thereof may be difficult. May occur.

The composition of the present invention further contains dimethylpolysiloxane (component C). The dimethylpolysiloxane can be selected from those having fluidity usually used in cosmetics and the like, and is not particularly limited.
The blending amount of dimethylpolysiloxane in the composition of the present invention is 0.01 to 3.0% by mass, more preferably 0.05 to 1.5% by mass, still more preferably 0.1 to 0.5% by mass. is there. If the blending amount is less than 0.01% by mass, it is difficult to obtain an effect of suppressing stickiness and improving the feeling of use, and if it exceeds 3% by mass, the amount of the active agent added for emulsification increases. May be sticky.

The composition of the present invention may contain other oil (component C ′) in addition to the dimethylpolysiloxane.
The other oil component (component C ′) is not particularly limited, and for example, one or more selected from hydrocarbon oil, ester oil, silicone oil (other than dimethylpolysiloxane), and the like may be used. Out. Specific examples are as follows.

Examples of fats and oils include linseed oil, camellia oil, macadamia nut oil, corn oil, olive oil, avocado oil, sasanqua oil, castor oil, safflower oil, kyounin oil, cinnamon oil, jojoba oil, grape oil, sunflower oil, almond oil Rapeseed oil, sesame oil, wheat germ oil, rice germ oil, rice bran oil, cottonseed oil, soybean oil, peanut oil, tea seed oil, evening primrose oil and the like.
Examples of fatty acids include heptanoic acid, octanoic acid, nonanoic acid, decanoic acid, pentadecanoic acid, heptadecanoic acid, nonadecanoic acid, isostearic acid, oleic acid, linoleic acid, linolenic acid, arachidonic acid and the like.

  Examples of ester oils include pentaerythritol tetraoctanoate, cetyl octanoate, hexyl laurate, isopropyl myristate, octyldodecyl myristate, octyl palmitate, isopropyl isostearate, octyl isopalmitate, isodecyl oleate, and ethylhexane. There are cetyl acid and the like.

Examples of the hydrocarbon oil include liquid paraffin, squalane, squalene, paraffin, isoparaffin, octane, decane, dodecane, isododecane, hexadecane, and isohexadecane.
Examples of the higher alcohol include octyl alcohol, isostearyl alcohol, oleyl alcohol, and the like.
Examples of the silicone oil include chain silicones such as methylphenylpolysiloxane and methylhydrogenpolysiloxane, and cyclic silicones such as octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, and dodecamethylcyclohexasiloxane.

  As the other oil component (C ′) used in the present invention, an oil component that is incompatible with the polyoxypropylene / polyoxyethylene copolymer alkyl ether (component B) is preferably selected. If Component B is compatible with the oil, a stable oil-in-water fine emulsion may not be obtained.

  The amount of the other oil component (C ′) used in the present invention is 0.01 to 5% by mass, preferably 0.1 to 3% by mass, based on the total amount of the oil component containing the dimethylpolysiloxane (component C). It is preferable that If the total blending amount of the oil is less than 0.01% by mass, phase inversion to water-in-oil type may not occur and the penetration feeling and water resistance after application may not be obtained. When it mix | blends, the quantity of the active agent added for emulsification may increase and it may become sticky.

  The compounding quantity of ethanol (component D) used for this invention is 1-30 mass%, Preferably it is 3-10 mass%. The oil-in-water emulsified liquid skin external preparation composition according to the present invention is characterized in that when ethanol is volatilized, it is phase-shifted to a water-in-oil type and exhibits excellent water resistance, etc. If it is less than 1% by mass, phase inversion is unlikely to occur, or phase inversion immediately after preparation may result in poor stability. On the other hand, if it exceeds 30% by mass, it takes too much time for the phase to be changed to a water-in-oil type after coating, and the effect may not be obtained properly.

  In addition, in the oil-in-water emulsified liquid skin external preparation composition according to the present invention, it is one of the characteristics that phase inversion to water-in-oil type is caused by volatilization of ethanol (component D). The system of the whole composition when ethanol is removed needs to be a water-in-oil emulsion system. Therefore, in the final formulation, the total amount of oil (component C + C ′) is 0.1 to 3% by mass, the water content is 40 to 95% by mass, and the amount of ethanol (component D) is 1 to 1%. It is particularly preferable to prepare so as to be 30% by mass.

The composition of the present invention further contains less than 0.1% by mass of an anionic surfactant (component E). By blending an anionic surfactant, stability at a particularly high temperature is further improved.
The anionic surfactants used in the present invention may be those usually used in cosmetics, for example, fatty acid soaps, N-acyl glutamates, carboxylate types such as alkyl ether acetic acids, α-olefin sulfonates, etc. Sulfonic acid types such as alkane sulfonates and alkylbenzene sulfonic acids, sulfate ester types such as higher alcohol sulfates, and phosphate ester salt types.

  Specific examples include fatty acid soaps (eg, sodium laurate, sodium palmitate, etc.), higher alkyl sulfates (eg, sodium lauryl sulfate, potassium lauryl sulfate), alkyl ether sulfates (eg, POE-lauryl). Triethanolamine sulfate, POE-sodium lauryl sulfate, etc.), N-acyl sarcosine acid (eg, sodium lauroyl sarcosine), higher fatty acid amide sulfonate (eg, sodium N-myristoyl-N-methyl taurate, methyl coconut oil fatty acid) Taurid sodium, lauryl methyl tauride sodium, etc.), phosphate esters (POE-oleyl ether sodium phosphate, POE-stearyl ether phosphate, etc.), sulfosuccinates (eg, di-2-ethyl Sodium silsulfosuccinate, monolauroyl monoethanolamide polyoxyethylene sodium sulfosuccinate, sodium lauryl polypropylene glycol sulfosuccinate, etc.), alkyl benzene sulfonates (eg, sodium linear dodecyl benzene sulfonate, triethanol amine linear dodecyl benzene sulfonate, linear Dodecylbenzenesulfonic acid, etc.), higher fatty acid ester sulfate ester salts (for example, hardened coconut oil fatty acid sodium glycerin sulfate, etc.), N-acyl glutamate (for example, N-coconut oil fatty acid acyl-L-glutamic acid potassium, N-lauroyl glutamic acid) Monosodium, disodium N-stearoyl glutamate, monosodium N-myristoyl-L-glutamate), sulfated oil ( Such as funnel oil), POE-alkyl ether carboxylic acid, POE-alkyl allyl ether carboxylate, α-olefin sulfonate, higher fatty acid ester sulfonate, secondary alcohol sulfate ester salt, higher fatty acid alkylolamide sulfate. Examples include ester salts, sodium lauroyl monoethanolamide succinate, ditriethanolamine N-palmitoyl aspartate, and sodium caseinate.

  The amount of the anionic surfactant in the composition of the present invention is less than 0.1% by mass, preferably 0.001 to 0.08% by mass, more preferably 0.001 to 0.05% by mass. is there. If it is less than 0.01% by mass, it is difficult to obtain the effect of the addition, and even if blended in an amount of 0.1% by mass or more, the effect is not further improved and stickiness may occur. This blending amount is generally clearly distinguished from a cleaning composition containing 0.5% by mass or more of an anionic surfactant.

  The composition of the present invention contains at least one (component F) selected from tranexamic acid and derivatives thereof (hereinafter referred to as “tranexamic acids”). Tranexamic acid (trans-4-aminomethylcyclohexane-1-carboxylic acid) and derivatives thereof are generally used as antiplasmin agents, and are known as components having particularly high safety in skin external use applications such as cosmetics. Yes.

  The tranexamic acids contained in the composition of the present invention may be those conventionally used in cosmetics and the like, and are not particularly limited. For example, in addition to tranexamic acid, its derivatives include tranexamic acid salts (magnesium salts, Metal salts such as calcium salt, sodium salt, potassium salt, phosphate, hydrochloride, hydrobromide, sulfate, etc.), amides of tranexamic acid (such as methylamide or its salts), dimers of tranexamic acid, etc. There is.

  The compounding amount of tranexamic acids in the composition of the present invention is 0.1 to 5.0% by mass, preferably 0.3 to 4.0% by mass, and more preferably 0.5 to 3.0% by mass. If it is less than 0.1% by mass, the effects of tranexamic acid (improving rough skin, whitening, etc.) will be insufficient, and if it exceeds 5.0% by mass, stickiness may be difficult to suppress.

The oil-in-water emulsified liquid skin external preparation composition of the present invention can be produced according to the method described in Patent Document 3.
Specifically, nonionic surfactant of HLB 5-9 (component A), polyoxypropylene / polyoxyethylene copolymer alkyl ether (component B), oil (component C and optionally component C ′), anion Surfactant (component E) and a part of water are mixed and stirred to prepare an oil-in-water single-phase microemulsion, and the obtained oil-in-water single-phase microemulsion is further mixed with ethanol (component D) and tranexam. An oil-in-water fine emulsion having an emulsified particle diameter of 20 to 600 nm is prepared by adding to an aqueous formulation containing an acid (component F) and emulsifying.
In the present invention, “single-phase microemulsion” means a transparent or translucent, one-liquid phase (a micellar aqueous phase in which the oil is completely solubilized, or water completely) in a water / surfactant / oil system. It is a composition of a thermodynamically stable system consisting of a micellar oil solution phase solubilized in water.

  The oil-in-water emulsified liquid skin external preparation composition according to the present invention can be used, for example, for skin cosmetics, hair cleansers, skin cleansers, hair stylings and the like. In addition, the oil-in-water emulsified liquid skin external preparation composition according to the present invention contains, in addition to the above essential components, optional components usually used in cosmetics, pharmaceuticals, etc. within a range that does not affect the stability. Can be blended. Examples of such optional components include the following.

  Moisturizers such as polyethylene glycol and its alkyl ethers, glycerin, sorbitol, xylitol, maltitol, mucopolysaccharide, hyaluronic acid, chondroitin sulfate, and chitosan. Thickeners such as methylcellulose, ethylcellulose, gum arabic, and polyvinyl alcohol. Organic solvents such as 1,3-butylene glycol. Antioxidants such as butylhydroxytoluene, tocopherol and phytic acid. Antibacterial preservatives such as benzoic acid, salicylic acid, sorbic acid, paraoxybenzoic acid esters (such as ethylparaben and butylparaben), and hexachlorophene. Amino acids and hydrochlorides such as glycine, alanine, valine, leucine, serine, threonine, phenylalanine, tyrosine, aspartic acid, asparagine, glutamine, taurine, arginine, histidine. Organic acids such as acyl sarcosine acid (eg, lauroyl sarcosine sodium), glutathione, citric acid, malic acid, tartaric acid, lactic acid.

  Vitamin A and its derivatives, vitamin B6 hydrochloride, vitamin B6 tripalmitate, vitamin B6 dioctanoate, vitamin B2 and its derivatives, vitamin B such as vitamin B12, vitamin B15 and its derivatives, ascorbic acid, ascorbic acid phosphate ( Salt), vitamin C such as ascorbic acid dipalmitate, α-tocopherol, β-tocopherol, γ-tocopherol, vitamin E acetate, vitamin E nicotinate and other vitamin E, vitamin D, vitamin H, pantothenic acid, pantethine, etc. Vitamins. Nicotinamide, benzyl nicotinate, γ-oryzanol, allantoin, glycyrrhizic acid (salt), glycyrrhetinic acid and its derivatives, hinokitiol, mucidin, bisabolol, eucalyptol, thymol, inositol, saponins (psychosaponin, carrot saponin, loofah) Various drugs such as saponin, muclodisaponin, etc.), pantothenyl ethyl ether, ethinyl estradiol, cephalanthin, and placenta extract.

Bark, Clara, Kouhone, Orange, Sage, Thyme, Yarrow, Zeni-Oyaku, Senkyu, Assembly, Spruce, Spruce, Birch, Horsetail, Loofah, Maronier, Yukishinoshita, Arnica, Lily, Artemisia, Peonies, Aloe, Gardenia, Sawan Natural extract extracted with solvent, alcohol, polyhydric alcohol, water, aqueous alcohol. Cationic surfactants such as stearyltrimethylammonium chloride, benzalkonium chloride, and laurylamine oxide. Metal sequestering agents such as disodium edetate, trisodium edetate, sodium citrate, sodium polyphosphate, sodium metaphosphate and gluconic acid.
In addition, a fragrance, a scrub agent, and the like can be appropriately blended within a range not impairing the stability.

  The oil-in-water emulsified liquid skin preparation for external use according to the present invention is preferably a transparent or translucent liquid cosmetic applied to the skin surface, typically with lotion.

  Hereinafter, the present invention will be described in more detail with reference to specific examples, but these do not limit the technical scope of the present invention. In addition, the prescription amounts in the following examples, comparative examples, and prescription examples are all mass%.

(Examples and Comparative Examples)
An oil-in-water fine emulsified liquid composition having the composition listed in Table 1 below was prepared.
Next, an actual use test was conducted with 20 professional panels using these compositions. The test items are penetration feeling, no stickiness when dried, and no sliminess. Each test panel evaluated each test item based on the following evaluation point criteria, and the total of the evaluation points was ranked in five stages according to the following evaluation criteria.

Evaluation criteria:
5 points: Excellent.
4 points: Excellent.
3 points: Normal.
2 points: Inferior.
1 point: Very inferior.
Evaluation criteria:
◎: Total score is 80 or more ○: Total score is 60 or more and less than 80 △: Total score is 40 or more and less than 60 ×: Total score is less than 40

Emulsified particle size:
The emulsified particle diameter (nm) of each composition was measured by a dynamic light scattering method using a light scattering photometer (DLS-7000: manufactured by Otsuka Electronics Co., Ltd.).

High temperature stability:
◯: After 1 month at 50 ° C., no change was observed.
Δ: After one month at 50 ° C., some creaming was confirmed at the top.
X: After one month at 50 ° C., clear creaming was confirmed at the top.

  (A) In Comparative Examples 1 to 3 using a nonionic surfactant having an HLB of 14.0, phase inversion to a water-in-oil type does not occur even by volatilization of ethanol. Water resistance was not sufficiently obtained. Further, in Comparative Example 2 in which tranexamic acid was blended, stickiness was generated, and in Comparative Example 3 in which xanthan gum was further blended, stickiness was suppressed to some extent, but a slimy feeling was generated.

  On the other hand, in the compositions (Examples 1 and 2 and Comparative Example 4) according to the present invention using a nonionic surfactant having an HLB of 5 to 9 (weighted average value), no stickiness or sliminess occurs and the penetration The feeling was also excellent. However, Comparative Example 4 containing no anionic activator was inferior in high temperature stability.

(Prescription Example 1)
Lotion for rough skin improvement:
Compounding ingredients Prescription amount (% by mass)
Purified water Residual ethanol 7
Glycerin 8
Dipropylene glycol 1
Ethanol 7
Polyoxyethylene (14) Polyoxypropylene (7)-
Dimethyl ether 1
Tranexamic acid 1
Dimethylpolysiloxane 0.2
Polyoxyethylene / methylpolysiloxane copolymer 0.15
Polyoxyethylene glyceryl isostearate 0.05
Citric acid appropriate amount sodium citrate appropriate amount phenoxyethanol appropriate amount edetate disodium appropriate amount perfume appropriate amount

Production method:
The oil and activator, polyoxyethylene (14) polyoxypropylene (7) -dimethyl ether, and a part of water were mixed and then added to the aqueous phase to obtain a lotion.

(Prescription example 2)
Beauty lotion:
Compounding ingredients Prescription amount (% by mass)
Purified water Residual ethanol 7
Glycerin 5
Dipropylene glycol 1
Ethanol 7
Polyoxyethylene (14) Polyoxypropylene (7)-
Dimethyl ether 1
Tranexamic acid 2
Dimethylpolysiloxane 0.2
Polyoxyethylene / methylpolysiloxane copolymer 0.15
Polyoxyethylene glyceryl isostearate 0.05
Citric acid appropriate amount sodium citrate appropriate amount phenoxyethanol appropriate amount edetate disodium appropriate amount perfume appropriate amount

Production method:
The oil and activator, polyoxyethylene (14) polyoxypropylene (7) -dimethyl ether, and a part of water were mixed and then added to the aqueous phase to obtain a lotion.

(Prescription Example 3)
Acne lotion:
Compounding ingredients Prescription amount (% by mass)
Purified water Residual ethanol 7
Glycerin 5
Dipropylene glycol 1
Ethanol 7
Polyoxyethylene (14) Polyoxypropylene (7)-
Dimethyl ether 1
Tranexamic acid 1
Salicylic acid 0.2
Dimethylpolysiloxane 0.2
Polyoxyethylene / methylpolysiloxane copolymer 0.15
Polyoxyethylene glyceryl isostearate 0.05
Citric acid appropriate amount sodium citrate appropriate amount phenoxyethanol appropriate amount edetate disodium appropriate amount perfume appropriate amount

Production method:
The oil and activator, polyoxyethylene (14) polyoxypropylene (7) -dimethyl ether, and a part of water were mixed and then added to the aqueous phase to obtain a lotion.

Claims (4)

(A) a nonionic surfactant of HLB 5-9,
(B) a polyoxypropylene / polyoxyethylene copolymer alkyl ether;
(C) dimethylpolysiloxane;
(D) ethanol,
(E) less than 0.1% by weight of an anionic surfactant;
(F) An oil-in-water emulsified liquid skin external preparation composition comprising tranexamic acid and having an emulsified particle diameter of 20 to 600 nm. The composition according to claim 1, wherein the content of the liquid oil containing (C) dimethylpolysiloxane is 0.1 to 3% by mass. The composition according to claim 1 or 2, wherein the amount of the (D) ethanol is 1 to 30% by mass and contains 40 to 95% by mass of water. The composition according to any one of claims 1 to 3, wherein the composition is a lotion or an essence for improving rough skin or whitening.