JP2013183981A - 人工呼吸器 - Google Patents
人工呼吸器 Download PDFInfo
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- JP2013183981A JP2013183981A JP2012053018A JP2012053018A JP2013183981A JP 2013183981 A JP2013183981 A JP 2013183981A JP 2012053018 A JP2012053018 A JP 2012053018A JP 2012053018 A JP2012053018 A JP 2012053018A JP 2013183981 A JP2013183981 A JP 2013183981A
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Abstract
【解決手段】酸素と酸素以外の医薬ガスとを混合したガスを吸気ガスとして患者に供与する人工呼吸器であって、酸素を含むガスを供給する第1のガス供給装置と、患者の気管に挿入され、留置される気管内管路と、第1のガス供給装置と気管内管路とを接続し、患者に第1のガス供給装置からの酸素を含むガスを導くための気管外管路と、気管外管路または気管内管路に接続され、酸素と酸素以外の医薬ガスとの混合ガスを気管外管路または気管内管路に供給する第2のガス供給装置とを備える、人工呼吸器。
【選択図】図1
Description
本発明の人工呼吸器において、第1のガス供給装置は高頻度振動換気法により酸素を含むガスを供給することが好ましい。
まず、非特許文献2で開示されている方法(以下、「方法A」とする)(比較例1)によるヘリウム・酸素吸入療法が、従来からの一般的な人工換気法、すなわちヘリウムおよび酸素混合ガスを用いないHFO人工呼吸(以下、「方法B」とする)(比較例2)より優れているか否かについて、事前に検証を行なった。
(1)方法Bで換気した後、動脈血酸素分圧および動脈血二酸化炭素分圧を測定した。
図1に示した例の本発明の人工呼吸器1を用いて、ヘリウムと酸素との混合ガスを気管外管路8の中途の分岐から供給したHFO人工呼吸(以下、「方法C」とする)(実施例1)と、上述した方法A(比較例1)とを交互に行ない、ウサギの動脈血酸素分圧および動脈血二酸化炭素分圧の変動を調べ、方法Cが方法Aと同等以上の効果があるかを検証した。
(1)方法Aで換気した後、動脈血酸素分圧および動脈血二酸化炭素分圧を測定した。
(5)方法Aで換気した後、動脈血酸素分圧および動脈血二酸化炭素分圧を測定した。
図2に示した例の本発明の人工呼吸器31を用いて、ヘリウムと酸素との混合ガスを気管内管路7の先端から供給したHFO人工呼吸(以下、「方法D」とする)(実施例2)と、上述した方法A(比較例1)とを交互に行ない、ウサギの動脈血酸素分圧および動脈血二酸化炭素分圧の変動を調べ、方法Dが方法Aと同等以上の効果があるかを検証した。
(1)方法Aで換気した後、動脈血酸素分圧および動脈血二酸化炭素分圧を測定した。
(5)方法Aで換気した後、動脈血酸素分圧および動脈血二酸化炭素分圧を測定した。
Claims (9)
- 酸素と酸素以外の医薬ガスとを混合したガスを吸気ガスとして患者に供与する人工呼吸器であって、
酸素を含むガスを供給する第1のガス供給装置と、
患者の気管に挿入され、留置される気管内管路と、
第1のガス供給装置と気管内管路とを接続し、患者に第1のガス供給装置からの酸素を含むガスを導くための気管外管路と、
気管外管路または気管内管路に接続され、酸素と酸素以外の医薬ガスとの混合ガスを気管外管路または気管内管路に供給する第2のガス供給装置とを備える、人工呼吸器。 - 酸素以外の医薬ガスがヘリウムである、請求項1に記載の人工呼吸器。
- 第1のガス供給装置が、高頻度振動換気法により酸素を含むガスを供給する、請求項1または2に記載の人工呼吸器。
- 第2のガス供給装置と気管内管路または気管外管路との間に、酸素と酸素以外の医薬ガスとの混合ガスの流量を測定するための流量計が接続されている、請求項1〜3のいずれかに記載の人工呼吸器。
- 第2のガス供給装置と気管内管路または気管外管路との間に、酸素と酸素以外の医薬ガスとの混合ガス中の酸素濃度を測定するための酸素濃度計が接続されている、請求項1〜4のいずれかに記載の人工呼吸器。
- 気管外管路と第1のガス供給装置との間に、第2のガス供給装置が接続された箇所より呼吸器側の酸素を含むガス中の酸素濃度を測定するための酸素濃度計が接続されている、請求項1〜5のいずれかに記載の人工呼吸器。
- 気管内管路が、独立した2つの流路を有し、一方の流路を第1のガス供給装置からの酸素を含むガスが流れ、他方の流路を第2のガス供給装置からの酸素と酸素以外の医薬ガスとの混合ガスが流れるように構成されている、請求項1〜6のいずれかに記載の人工呼吸器。
- 第1のガス供給装置からの酸素を含むガスが圧縮空気を含む、請求項1〜7のいずれかに記載の人工呼吸器。
- 第1のガス供給装置は、気管内管路、気管外管路を経た患者からの呼気ガスを排気するように構成されている、請求項1〜8のいずれかに記載の人工呼吸器。
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US14/383,498 US20150059743A1 (en) | 2012-03-09 | 2013-02-28 | Ventilator |
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WO2021206771A1 (en) | 2020-04-10 | 2021-10-14 | Jerome Canady Research Institute for Advanced Biological and Technological Sciences | System and method for treatment of respiratory infections and lung cancer with cold atmospheric plasma |
JP2023545337A (ja) | 2020-04-10 | 2023-10-30 | ジェローム カナディ リサーチ インスティチュート フォー アドバンスト バイオロジカル アンド テクノロジカル サイエンシズ | 寒冷大気圧プラズマを用いた呼吸器感染および肺がんの処置のためのシステムおよび方法 |
LU101785B1 (en) | 2020-05-08 | 2021-11-08 | Jerome Canady Research Institute For Advanced Biological And Tech Sciences | System for treatment of respiratory infections and lung cancer with cold atmospheric plasma |
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