JP2013085528A - Staining material-contamination elimination facility - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a staining material-contamination elimination facility, capable of providing a facility which is provided with changerooms for men and women with easy and rapid access while perfectly eliminating contamination with staining material associated with entrance and leaving, and is further highly convenient for facility operations.SOLUTION: In an area of laboratories 1 or cultivation rooms which is cut off from the outside and separated from a section without traffical restriction within a building, gender-segregated dressing spaces of a changeroom (men) 2 and a changeroom (women) 3 are provided as shared dressing spaces of each laboratory or cultivation room. Each of the dressing spaces independently includes a dressing room 7 for laboratory coats or the like and an undressing room 8 for laboratory coats or the like in leaving, and the area is necessarily accessed through the dressing spaces. Each dressing space is three-dimensionally accessed from the upper floor or lower floor of the area through a staircase 9 or the like.

Description

  The present invention relates to a layout of a highly important facility such as a biohazard animal breeding facility in a facility such as a laboratory or a culture room that needs to ensure biological safety, such as microorganisms, cell culture, genetic recombination, and animal experiments. Contaminant contamination elimination facility related to

  At the biohazard animal breeding facility, in order to take measures to prevent animal escapes, in order to get out of the area, it is necessary to pass through multiple doors. For facilities that require safety, for example, “Laboratory Biosafety Guidelines” published by WHO are used as international guidelines.

For example, in this guideline, main items related to the facility layout required in facility management and work management of biosafety level 3 are as follows.
(1) Wear protective clothing for laboratories (separate from daily clothing), and don't wear protective clothing outside the laboratory. Protective clothing after use must be decontaminated before washing. The When handling specific materials, you must take off external clothing and change into special laboratory protective clothing. (Level 4 facilities require a complete change of clothes.)
(2) The laboratory must be separated from areas in the building where traffic is not restricted. Enhance isolation by entering through the front room. The front room will be equipped with equipment to separate clean clothes and contaminated clothes, and a shower if necessary.
(3) Install a controlled ventilation system that ensures airflow in a certain direction from the entrance to the laboratory.

  As a response to such a request, a layout as shown in FIG. 4 is assumed. In the figure, 1 is a laboratory etc., 2 and 3 are changing rooms (male), changing rooms (female), 4 is a common approach path to a plurality of laboratory rooms 1 and 5 is an exit path.

  It is a flat access method, and enters the changing rooms 2 and 3 of the men and women from the outside 6, changes from the external clothes to the experimental clothes, etc., enters the laboratory 1 etc. via the approach path 4. After finishing the experiment 1 and the like, the exit route 5 is followed to return to the changing rooms 2 and 3 of the men and women, and the clothes for the experiment are undressed and the clothes are changed to the external clothes.

The following Patent Document 1 is proposed as a vector production facility that satisfies the physical containment level P2 or P3 defined in the recombinant DNA experiment guideline and the safety standard defined in GMP and has excellent productivity. And a preparation chamber, a first airlock front chamber, a vector preparation chamber, a post-airlock chamber, and a sterilization chamber, and an operator enters the preparation chamber, the first airlock front chamber, and the vector preparation Doors are provided between the chambers so as to form a restricted flow line in which the chambers and the chambers after the airlock are moved in this order, and the sterilization chambers are moved out. An indoor pressure adjusting means for adjusting the indoor pressure is provided.
JP 2003-47457 A

  A changing room was provided outside the entrance door of the preparation room, and a dressing room was provided outside the exit door of the sterilization chamber.

  In Patent Document 1, the rooms formed in the cell culture facility are separated from each other, and the storage room, the processing room, the cell culture room, and the like of the source cells are separated, and the work in each room is performed. The cell culture room has a changing room and a dressing room to prevent disturbance of cleanliness by workers in the cell culture room. Provided to control the pressure in each chamber.

  And since the flow lines of workers and raw materials and instruments necessary for vector production are restricted in one direction, workers before vector production and workers after production do not come into contact with each other. In addition, there is no fear that the air in the vector preparation chamber leaks to the outside, and all waste and carry-out can be sterilized by a high-pressure steam sterilizer before being carried outside.

Patent Document 2 listed below is a genetically modified plant factory, which is provided with a nutrient solution cultivation apparatus for cultivating a genetically modified plant and an air conditioner with an exhaust filter, and is a closed cultivation area maintained at a negative pressure, the cultivation area A plant inactivation device is installed that is adjacent to the air inlet with airlock and is maintained at a negative pressure weaker than the cultivation area and inactivates the genetically modified plant after harvesting so that it does not germinate, grow, reproduce or cross. An inactivation area, a manufacturing area provided with a device that is adjacent to the inactivation area via a carrier port with an airlock and is maintained at a positive pressure and that prepares the inactivated genetically modified plant into food or medicine, It comprises a drainage sterilizer for sterilizing wastewater from the cultivation area, and a worker entrance with airlock provided in the cultivation area and the manufacturing area.
JP 2008-161114 A

  In Patent Document 2, a worker wears work clothes in a changing room, and then enters one of the cultivation rooms from the worker entrance through the front room and an entrance with an airtight door. Moreover, after the work in the cultivation room is completed, the worker exits from the worker's exit to the dressing room through the exit with the airtight door and the rear room of the cultivation room, and changes work clothes.

  Thus, even when cultivating different genetically modified plants P in each cultivation room by separating the entry flow line and the leaving flow line of the worker with respect to each cultivation room, due to the intersection of the movement lines of the worker It is said that contamination and leakage of the plant P can be surely prevented.

Patent Document 3 listed below includes a plurality of cell culture chambers, a cell transfer robot chamber in which a robot that automatically transfers cells is placed between each culture chamber, a raw material processing chamber, and a product processing chamber, An automatic cell culture facility characterized in that a material installation chamber for setting a medium in a culture apparatus that performs automatic cell culture in a culture chamber is provided in each culture chamber. The shared material installation room is provided with a dressing room for entering and exiting the room and a dressing room.
JP 2009-219415 A

  According to this Patent Document 3, an automatic cell culture device is placed in each cell culture chamber, and raw material cells are automatically supplied to a selected cell culture chamber by a transfer robot, and product cells after culture are supplied to a product processing chamber. Can be automatically unloaded. This automates the setting of the cells into the automatic cell culture apparatus and the removal after the culture, and can be automated, cleaned, and saved in space. In addition, the material installation room for supplying the culture medium to the cell culture room is a shared space for the plurality of cell culture rooms. By installing the dressing room and the dressing room in and out of the room, cross contamination can be prevented. It is possible to effectively use the facility space while preventing it.

  In the case of the layout shown in FIG. 4, it is necessary to arrange the exit path 5 so as to surround the outer periphery of the laboratory 1 or the like, and the experimenter goes around this laboratory area at the longest from entry to exit. There is a need.

  Moreover, in the said patent document 1 and patent document 2, the entrance / exit to the culture room (cultivation room) is made into another route completely including the changing clothes, and contamination of contamination is provided by providing an independent changing room and a changing room. We are trying to prevent it, but if we try to increase production efficiency, we have to make the culture room (cultivation room) multi-chamber. However, the multi-room structure causes a problem that a large space is required for a changing room attached to each room.

  Patent Document 3 has a simple configuration in which a common material installation room is provided, but the common material installation room is provided with a clothing room and an undressing room for entering and exiting the room, and is independent of each laboratory. A plurality of changing rooms (clothing rooms / undressing rooms) are provided, and management convenience, facility utilization efficiency, and area utilization efficiency in terms of architectural planning are impaired.

  The object of the present invention is to eliminate the inconvenience of the conventional example, completely eliminate contamination of contaminants due to entry / exit, provide men's and women's changing rooms, have clear and short access, and provide no unnecessary passages. It is an object of the present invention to provide a pollutant contamination elimination facility capable of providing a facility with high area use efficiency and high facility convenience.

  In order to achieve the above object, the present invention according to claim 1 is characterized in that each laboratory, culture room, etc. in an area such as a laboratory or a culture room that is isolated from the outside and separated from an area where traffic is not restricted in the building. There are gender-specific changing spaces as common changing spaces for culture rooms, etc., and each changing space has an independent dressing room for experimental clothes and a separate undressing room for test clothes when leaving, etc. It is always via a changing space and has a gist of three-dimensional access.

  According to the first aspect of the present invention, it is possible to prevent contamination of pollutants by completely entering and leaving the laboratory and the like including changing clothes. Moreover, in facilities provided with a plurality of laboratories and the like, in order to facilitate the management of changing clothes, etc., a common changing space for each laboratory can be provided, thereby improving the utilization efficiency of the facility.

  Although it is a common changing space for each laboratory, there can be separate changing rooms for men and women, and each changing space has a changing room for experiment and other clothes and a changing room for leaving the experiment. Each is provided independently.

  In relation to the changing space, each of the plurality of laboratories is independent and can be accessed without changing through other laboratories.

  The flow lines in the changing space and the laboratory are as short and simple as possible in terms of condemnation in the event of a fire.

  In the case of gender-specific changing rooms, the approach from the same floor cannot physically eliminate the possibility of cross-contamination that can occur in front of the changing room, but a three-way access can realize a complete one-way flow line.

  The gist of the present invention described in claim 2 is that the three-dimensional access is to access the changing space from the upper floor to the lower floor of the area by stairs or the like.

  According to the second aspect of the present invention, three-dimensional access is achieved by accessing the changing space by using stairs from the upper floor or lower floor of the area, so that the one-way flow line can be easily obtained by the usual means of stairs. It can be secured.

  The gist of the present invention described in claim 3 is that a plurality of changing spaces are accessed from the upper floor through the ceiling pocket space of each laboratory or culture room.

  According to the present invention described in claim 3, in a facility that provides a laboratory or a culture room of a plurality of areas having different experimental purposes and contents, the facility is accessed in a facility that requires a changing space for each area. By using the stairs from the upper floor of the area, access the changing space in each area via a space with sufficient height that allows human traffic to the ceiling pocket, etc. It is sufficient to install a minimum number of stairs to access each area, and the area of the upper floor can be used effectively as a work space.

  As described above, even if the contamination-excluding facility for pollutants of the present invention includes a plurality of laboratories and the like, it is easy to manage the dressing and the like by sharing the dressing space with each laboratory. The use efficiency of the facility can be improved, and a changing room for each gender can be set up. In addition, each changing space has a changing room for experimental clothes and a changing room for leaving clothes. In relation to the changing space, each laboratory is independent and can access the changing room without going through other laboratories. The line can be as short and simple as possible.

  Hereinafter, embodiments of the present invention will be described in detail with reference to the drawings. FIG. 1 is an explanatory view of a contaminant-excluding facility according to the present invention. FIG. 2 is a plan view showing an embodiment of the same as above, and the same components as those in FIG. In the figure, 1 is a laboratory etc., 2 and 3 are changing rooms (male), changing rooms (female), 4 is a common approach path to a plurality of laboratory rooms 1 and 5 is an exit path.

  The laboratory 1 or the like in the building is, for example, a laboratory that is blocked from the outside and separated from an area where traffic in the building is not restricted, for example, by providing it on the second or higher floors or in the basement. It is configured as an area such as a culture room.

  Each laboratory, such as a laboratory or culture room 1 has a plurality of coexisting rooms. The changing room (male) 2 and the changing room (female) 3 have entrances facing the entrance path 4 and exit path 5. Since the approach path 4 and the exit path 5 are common to a plurality of laboratories 1 and the like, they are configured as a common dressing space for each laboratory 1 and the like, and are gender-specific dressing spaces. In the example of FIG. 2, the entrance path 4 is a preparation corridor and the entrance of the laboratory 1 (pre-infection room) faces this, and the exit path 5 is the experiment corridor and the exit of the laboratory 1 (post-infection room). Faces this.

  As shown in FIG. 2, the changing spaces of the changing room (male) 2 and the changing room (female) 3 are divided into a clothing room 7 such as experimental clothes and a changing room 8 such as experimental clothes when leaving by doors and partitions. Each was provided independently by partitioning. Two dressing rooms 7, 7 'are arranged with the undressing room 8 in the middle, of which the dressing room 7 has an exit on the entrance path 4 and the subsequent dressing room 7' has an entrance on the exit path 5.

  Changing room as access to area (outside 6) where the stairway 9 to the upper or lower floor is not blocked from the outside and the traffic in the building is not restricted (external 6) and the laboratory 1 separated from here The changing space of (male) 2 and changing room (female) 3 is three-dimensionally accessed from the upper floor to the lower floor by stairs 9 and the like.

  In FIG. 2, the chain line arrow indicates a male researcher, the two-dot chain line arrow indicates a female researcher, and the straight arrow indicates a common line, entering the building from outside 6 and restricting traffic in the building where there are living rooms and offices. Enter the changing room (male) 2 and the changing room (female) 3 for both men and women by the stairs 9 after passing through the non-existing area. This staircase 9 has a structure that allows access only to the changing room (male) 2 and the changing room (female) 3 of the male and female.

  In the undressing room 8 and the dressing room 7, the clothes are changed from the external clothes to the experimental clothes such as white robes, leave the clothing room 7, enter the laboratory 1, etc. via the approach path 4.

  After completing the experiment, etc., exit from each laboratory 1, etc., and then return to the changing room (male) 2 and the changing room (female) 3 of each man and woman (entering the dressing room 7 ') through the exit path 5 In the room 7 ′ and the dressing room 8, the clothes for the experiment are undressed and the clothes are changed to the external clothes.

  As another embodiment, the three-dimensional access may be an elevator or the like instead of the stairs 9, and the changing room for men and women is three-dimensionally configured, and the experiment space and the changing space are three-dimensionally configured. It is possible.

  In this case, furthermore, the laboratory usually requires a lot of space in the ceiling to maintain cleanliness, etc., and requires a floor height much higher than the ceiling height required for the layer room. The three-dimensional configuration allows the space in the ceiling to be effectively used three-dimensionally.

  As another embodiment, as shown in FIG. 3, the present invention according to claim 3 accesses a plurality of changing spaces from the upper floor by passing through a ceiling space such as each laboratory or culture room. It can also be done.

  FIG. 3 is a cross-sectional view of a facility provided with changing spaces for areas I and II such as a plurality of laboratories and culture rooms. To access the laboratory or culture room from the office on the upper floor, go down one staircase and install it in a space that requires high space in the ceiling, such as the laboratory or culture room. After passing through the passageway, each changing space is accessed by the stairs provided in each of the areas I and II, and the changing room for each man and woman is changed to the laboratory and the culture room.

  After finishing the experiment, undressing and changing clothes in each changing room, going up the stairs to the passageway, going up the stairs to the office room on the upper floor through the passageway, and returning to the office. Each area requires a staircase, but the office can be accessed by providing only one staircase, and the office space can be used effectively.

  Although the above embodiments have been described as laboratories that need to ensure biological safety, in facilities other than bio-related facilities such as isotope facilities and semiconductor clean rooms, other than experiment wearing in laboratories other than laboratories and culture rooms The present invention can also be applied when wearing work clothes.

It is explanatory drawing of the contamination contamination exclusion facility of this invention. It is a top view which shows one embodiment of the contamination contamination exclusion facility of this invention. It is sectional drawing which shows other embodiment of the contamination contamination exclusion facility of this invention. It is explanatory drawing which shows a prior art example.

1 ... Laboratory etc. 2 ... Changing room (male)
3 ... Changing room (female) 4 ... Entrance path 5 ... Exit path 6 ... Outside 7, 7 '... Dressing room 8 ... Dressing room 9 ... Stairs

Claims (3)

In areas such as laboratories and culture rooms that are blocked from the outside and separated from areas where traffic within the building is not restricted,
There are gender-specific changing spaces as shared changing spaces in each laboratory and culture room.
Each changing space has an independent dressing room for experiment clothes and a dressing room for experiment clothes when leaving,
Contaminant contamination elimination facility characterized in that there is always a three-dimensional access to the area via a changing space.   The contamination-excluding facility for pollutants according to claim 1, wherein three-dimensional access is to access a changing space from above or below the area by stairs.   The contamination exclusion facility according to claim 1 or 2, wherein a plurality of changing spaces are accessed from an upper floor through a ceiling pocket space such as each laboratory or culture room.

Images