JP2013047264A5 - - Google Patents
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- JP2013047264A5 JP2013047264A5 JP2012243686A JP2012243686A JP2013047264A5 JP 2013047264 A5 JP2013047264 A5 JP 2013047264A5 JP 2012243686 A JP2012243686 A JP 2012243686A JP 2012243686 A JP2012243686 A JP 2012243686A JP 2013047264 A5 JP2013047264 A5 JP 2013047264A5
- Authority
- JP
- Japan
- Prior art keywords
- ceramic
- particles
- emulsion
- diameter
- biological material
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Claims (7)
- 前記セラミック粒子は、直径１〜５０ｎｍの平均孔径サイズを有し、平均粒子サイズが０．０５〜５００ミクロンであり、直径５〜５００ｎｍの一次粒子の凝集体を含み、
前記セラミック粒子は、凝集剤をエマルションに加えることなく、セラミック前駆物質及び生物学的物質を含む極性相が非極性相中に分散された乳液から、前記一次粒子を凝集させることによって形成され、前記セラミック粒子は残余の凝集剤フリーである、放出可能な生物学的物質を含むセラミック粒子。 - 前記一次粒子の直径が５〜１００ｎｍである、請求項１記載のセラミック粒子。
- 前記セラミック粒子は、直径１〜１０ｎｍの平均孔径サイズを有する、請求項１又は２記載のセラミック粒子。
- ａ）非極性溶媒に溶解した界面活性剤の溶液を、前記セラミック前駆物質および生物学的物質と混合して、乳液を形成すること；及び
ｂ）生物学的物質を含むセラミック粒子を形成するために、前記乳液中に凝集剤を添加することなく、前記乳液中で前記一次粒子を凝集させること；を含み、
前記セラミック前駆物質は、直径が５〜５００ｎｍの一次粒子を含むゾルであるセラミック前駆体を含む、請求項１〜３のいずれかに記載のセラミック粒子。 - 生物学的物質がタンパク質を含む、請求項１〜４のいずれかに記載のセラミック粒子。
- 生物学的物質が、粒子全体に渡って実質的に均一に分布している、請求項１〜５のいずれかに記載のセラミック粒子。
- 生物学的物質が、粒子から放出された後でも生物学的に活性を持つ、請求項１〜６のいずれかに記載のセラミック粒子。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2004907219A AU2004907219A0 (en) | 2004-12-20 | Controlled release of biological entities | |
| AU2004907219 | 2004-12-20 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008518535A Division JP5593030B2 (ja) | 2004-12-20 | 2005-12-20 | 生物学的物質の調節放出 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013047264A JP2013047264A (ja) | 2013-03-07 |
| JP2013047264A5 true JP2013047264A5 (ja) | 2013-04-18 |
| JP5727445B2 JP5727445B2 (ja) | 2015-06-03 |
Family
ID=36601253
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008518535A Expired - Fee Related JP5593030B2 (ja) | 2004-12-20 | 2005-12-20 | 生物学的物質の調節放出 |
| JP2012243686A Expired - Fee Related JP5727445B2 (ja) | 2004-12-20 | 2012-11-05 | 生物学的物質の調節放出 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008518535A Expired - Fee Related JP5593030B2 (ja) | 2004-12-20 | 2005-12-20 | 生物学的物質の調節放出 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US8992986B2 (ja) |
| EP (1) | EP1838289B1 (ja) |
| JP (2) | JP5593030B2 (ja) |
| KR (1) | KR20070104563A (ja) |
| CN (1) | CN101106978A (ja) |
| BR (1) | BRPI0519139A2 (ja) |
| CA (1) | CA2591344C (ja) |
| MX (1) | MX2007007373A (ja) |
| NZ (1) | NZ556082A (ja) |
| WO (1) | WO2006066317A1 (ja) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6101683A (en) | 1998-04-02 | 2000-08-15 | Avery Dennison Corporation | Loop fastener, fastener clip including same and loop fastener dispensing tool |
| WO2009132411A1 (en) * | 2008-04-28 | 2009-11-05 | The University Of British Columbia | Polymer-free drug delivery system for implantable medical devices |
| NZ595185A (en) * | 2009-03-27 | 2012-11-30 | Australian Nuclear Science Tec | Triggered release of a compound or composition into solution using porus particles |
| KR20190006576A (ko) * | 2010-08-16 | 2019-01-18 | 오스트레일리안 뉴클리어 사이언스 앤드 테크놀로지 오가니제이션 | 생체분자의 전달을 위한 세라믹 입자를 포함하는 미립자 물질 및 미립자 물질을 포함하는 약학적 조성물 |
| US10001501B2 (en) | 2015-12-31 | 2018-06-19 | Universal Diagnostics, S. L. | Systems and methods for automated, customizable sample preparation for detection of metabolites and lipids |
| CN107522868B (zh) * | 2017-10-16 | 2021-01-08 | 湖北工业大学 | 环氧纳米二氧化硅/嵌段聚合物复合乳液的制备方法 |
| US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3850751A (en) * | 1973-02-16 | 1974-11-26 | Corning Glass Works | Enzymes immobilized on porous inorganic support materials |
| CH624011A5 (ja) * | 1977-08-05 | 1981-07-15 | Battelle Memorial Institute | |
| CA1253129A (en) * | 1984-02-09 | 1989-04-25 | Thomas R. Jones | Porous inorganic materials |
| JPH0717371B2 (ja) * | 1986-09-05 | 1995-03-01 | 株式会社資生堂 | 球状の有機複合粘土鉱物及びその製造法 |
| JPH05261274A (ja) | 1992-03-23 | 1993-10-12 | Lion Corp | 金属化合物の球形粒子の製造方法 |
| JP3310291B2 (ja) | 1992-08-13 | 2002-08-05 | ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア | 骨組織のｉｎ ｖｉｔｒｏ合成のための生物活性物質テンプレート |
| US5817327A (en) | 1994-07-27 | 1998-10-06 | The Trustees Of The University Of Pennsylvania | Incorporation of biologically active molecules into bioactive glasses |
| US6096324A (en) * | 1995-06-13 | 2000-08-01 | Laboratory Skin Care | Methods of delivering materials into the skin, and compositions used therein |
| US6764690B2 (en) | 1996-05-29 | 2004-07-20 | Delsitech Oy | Dissolvable oxides for biological applications |
| US5972384A (en) | 1997-10-01 | 1999-10-26 | University Of Maryland, Baltimore | Use of biologically active glass as a drug delivery system |
| ES2382536T3 (es) | 1998-08-13 | 2012-06-11 | Sol-Gel Technologies Ltd. | Procedimiento de preparación de microcápsulas de óxido cargadas con moléculas funcionales y productos obtenidos a partir de las mismas |
| IL138990A0 (en) | 1999-02-12 | 2001-11-25 | Biostream Inc | Matrices for drug delivery and methods for making and using the same |
| WO2001001139A2 (en) | 1999-06-24 | 2001-01-04 | Mcmaster University | Incorporation and appliations of biomolecular interactions within a carrier |
| JP2001038193A (ja) * | 1999-07-28 | 2001-02-13 | Nippon Millipore Kk | 複合シリカマイクロカプセルの製造方法と複合シリカマイクロカプセルの芯物質の固定化と徐放作用の制御方法。 |
| EP1202745A4 (en) | 1999-08-16 | 2004-09-22 | Henceforth Hibernia Inc | THERAPEUTIC AND PROPHYLACTIC COMPOSITIONS CONTAINING CATALYTIC BIOMIMETIC SOLIDS AND METHODS OF PREPARING AND USING SAME |
| AUPQ573300A0 (en) * | 2000-02-21 | 2000-03-16 | Australian Nuclear Science & Technology Organisation | Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use |
| US6303290B1 (en) | 2000-09-13 | 2001-10-16 | The Trustees Of The University Of Pennsylvania | Encapsulation of biomaterials in porous glass-like matrices prepared via an aqueous colloidal sol-gel process |
| US6596262B2 (en) | 2001-02-15 | 2003-07-22 | Aeropharm Technology Incorporated | Modulated release particles for aerosol delivery |
| US6485707B2 (en) | 2001-02-15 | 2002-11-26 | Aeropharm Technology Incorporated | Modulated release particles for aerosol delivery |
| US6544497B2 (en) | 2001-02-15 | 2003-04-08 | Aeropharm Technology Incorporated | Modulated release particles for aerosol delivery |
| CA2465779A1 (en) | 2001-11-20 | 2003-05-30 | Advanced Inhalation Research, Inc. | Compositions for sustained action product delivery |
| US7399495B2 (en) | 2002-04-30 | 2008-07-15 | Solae, Llc | Protein product imparting high water dispersibility |
| JP4192235B2 (ja) * | 2002-04-30 | 2008-12-10 | 独立行政法人産業技術総合研究所 | 徐放機能を有するメソポーラス無機材料 |
| KR20050089961A (ko) * | 2002-10-11 | 2005-09-09 | 벡투라 리미티드 | 유기 폴리머 물질과 결합된 무기 입자들을 포함하고 고형의망상형 매트릭스를 형성하는 약학적 부형제, 조성물, 그의제조 및 용도 |
| US20040180091A1 (en) * | 2003-03-13 | 2004-09-16 | Chang-Yi Lin | Carbonated hydroxyapatite-based microspherical composites for biomedical uses |
| JP2005307120A (ja) * | 2004-04-26 | 2005-11-04 | Mitsubishi Chemicals Corp | 徐放剤及びそれを用いた徐放材 |
| KR20070097439A (ko) * | 2004-11-15 | 2007-10-04 | 오스트레일리언뉴클리어사이언스앤드테크놀로지오거나이제이션 | 마이크로에멀션의 제어된 비안정화로부터 제조된 고형분입자 |
| US20090098044A1 (en) * | 2004-11-15 | 2009-04-16 | Australian Nuclear Science And Technology Organisation | Solid particles from controlled destabilisation of microemulsions |
-
2005
- 2005-12-20 US US11/721,728 patent/US8992986B2/en not_active Expired - Fee Related
- 2005-12-20 NZ NZ556082A patent/NZ556082A/en not_active IP Right Cessation
- 2005-12-20 CN CNA2005800470576A patent/CN101106978A/zh active Pending
- 2005-12-20 WO PCT/AU2005/001915 patent/WO2006066317A1/en active Application Filing
- 2005-12-20 EP EP05818407.8A patent/EP1838289B1/en not_active Not-in-force
- 2005-12-20 JP JP2008518535A patent/JP5593030B2/ja not_active Expired - Fee Related
- 2005-12-20 MX MX2007007373A patent/MX2007007373A/es active IP Right Grant
- 2005-12-20 KR KR1020077016764A patent/KR20070104563A/ko active Search and Examination
- 2005-12-20 CA CA2591344A patent/CA2591344C/en active Active
- 2005-12-20 BR BRPI0519139-4A patent/BRPI0519139A2/pt not_active Application Discontinuation
-
2012
- 2012-11-05 JP JP2012243686A patent/JP5727445B2/ja not_active Expired - Fee Related
-
2015
- 2015-02-03 US US14/612,739 patent/US9717688B2/en active Active
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