JP2013046616A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2013046616A5 JP2013046616A5 JP2012202508A JP2012202508A JP2013046616A5 JP 2013046616 A5 JP2013046616 A5 JP 2013046616A5 JP 2012202508 A JP2012202508 A JP 2012202508A JP 2012202508 A JP2012202508 A JP 2012202508A JP 2013046616 A5 JP2013046616 A5 JP 2013046616A5
- Authority
- JP
- Japan
- Prior art keywords
- base sequence
- seq
- sequence represented
- rna strand
- rna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims description 32
- 108091033319 polynucleotide Proteins 0.000 claims description 10
- 102000040430 polynucleotide Human genes 0.000 claims description 10
- 239000002157 polynucleotide Substances 0.000 claims description 10
- 108091030071 RNAI Proteins 0.000 claims description 8
- 230000009368 gene silencing by RNA Effects 0.000 claims description 8
- 230000000295 complement effect Effects 0.000 claims description 3
- 210000001778 pluripotent stem cell Anatomy 0.000 claims 10
- 210000004027 cell Anatomy 0.000 claims 7
- 239000000411 inducer Substances 0.000 claims 4
- 201000011510 cancer Diseases 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 210000004881 tumor cell Anatomy 0.000 claims 2
- 108091027967 Small hairpin RNA Proteins 0.000 claims 1
- 108020004459 Small interfering RNA Proteins 0.000 claims 1
- 230000033228 biological regulation Effects 0.000 claims 1
- 239000002771 cell marker Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000001737 promoting effect Effects 0.000 claims 1
- 230000001105 regulatory effect Effects 0.000 claims 1
- 239000004055 small Interfering RNA Substances 0.000 claims 1
- 210000001082 somatic cell Anatomy 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
- 230000000694 effects Effects 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012202508A JP2013046616A (ja) | 2010-07-12 | 2012-09-14 | ｓｉＲＮＡ導入による新規ｈｉＰＳＣ作製法 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010158192 | 2010-07-12 | ||
| JP2010158193 | 2010-07-12 | ||
| JP2010158193 | 2010-07-12 | ||
| JP2010158194 | 2010-07-12 | ||
| JP2010158194 | 2010-07-12 | ||
| JP2010158192 | 2010-07-12 | ||
| JP2012202508A JP2013046616A (ja) | 2010-07-12 | 2012-09-14 | ｓｉＲＮＡ導入による新規ｈｉＰＳＣ作製法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011530188A Division JP5099570B2 (ja) | 2010-07-12 | 2011-06-28 | ｓｉＲＮＡ導入による新規ｈｉＰＳＣ作製法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013046616A JP2013046616A (ja) | 2013-03-07 |
| JP2013046616A5 true JP2013046616A5 (https=) | 2014-08-14 |
Family
ID=45469308
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011530189A Expired - Fee Related JP5099571B2 (ja) | 2010-07-12 | 2011-06-28 | ｍｉＲＮＡ導入による新規ｈｉＰＳＣ作製法 |
| JP2011530188A Expired - Fee Related JP5099570B2 (ja) | 2010-07-12 | 2011-06-28 | ｓｉＲＮＡ導入による新規ｈｉＰＳＣ作製法 |
| JP2012202508A Pending JP2013046616A (ja) | 2010-07-12 | 2012-09-14 | ｓｉＲＮＡ導入による新規ｈｉＰＳＣ作製法 |
| JP2012202509A Pending JP2013034479A (ja) | 2010-07-12 | 2012-09-14 | ｍｉＲＮＡ導入による新規ｈｉＰＳＣ作製法 |
| JP2013264240A Expired - Fee Related JP5845493B2 (ja) | 2010-07-12 | 2013-12-20 | ｍｉＲＮＡ導入による新規ｈｉＰＳＣ作製法 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011530189A Expired - Fee Related JP5099571B2 (ja) | 2010-07-12 | 2011-06-28 | ｍｉＲＮＡ導入による新規ｈｉＰＳＣ作製法 |
| JP2011530188A Expired - Fee Related JP5099570B2 (ja) | 2010-07-12 | 2011-06-28 | ｓｉＲＮＡ導入による新規ｈｉＰＳＣ作製法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012202509A Pending JP2013034479A (ja) | 2010-07-12 | 2012-09-14 | ｍｉＲＮＡ導入による新規ｈｉＰＳＣ作製法 |
| JP2013264240A Expired - Fee Related JP5845493B2 (ja) | 2010-07-12 | 2013-12-20 | ｍｉＲＮＡ導入による新規ｈｉＰＳＣ作製法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US9476041B2 (https=) |
| EP (2) | EP2594643B1 (https=) |
| JP (5) | JP5099571B2 (https=) |
| CN (2) | CN103189511B (https=) |
| WO (2) | WO2012008301A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103189511B (zh) | 2010-07-12 | 2016-10-12 | 国立大学法人鸟取大学 | 利用siRNA导入的新型hiPSC制作法 |
| EP2686418A4 (en) | 2011-03-17 | 2015-04-22 | Minerva Biotechnologies Corp | METHOD FOR THE PRODUCTION OF PLURIPOTENTAL STEM CELLS |
| EP2768945B1 (en) | 2011-10-17 | 2022-01-05 | Minerva Biotechnologies Corporation | Media for stem cell proliferation and induction |
| EP2844744A2 (en) * | 2012-02-22 | 2015-03-11 | Brainstem Biotec Ltd. | MicroRNAS FOR THE GENERATION OF ASTROCYTES |
| JP6748430B2 (ja) * | 2012-07-13 | 2020-09-02 | ミネルバ バイオテクノロジーズ コーポレーション | より未分化状態への細胞の誘導方法 |
| JPWO2015030149A1 (ja) * | 2013-08-29 | 2017-03-02 | 国立大学法人鳥取大学 | 細胞のアンチエイジングに関連する生体分子群 |
| TW201610152A (zh) * | 2013-11-22 | 2016-03-16 | 國立臺灣大學 | 微ｒｎａ１４６－ａ及其於診斷、治療及預防小核醣核酸病毒感染之用途及微ｒｎａ１４６－ａ拮抗劑 |
| CN104109670B (zh) * | 2014-03-12 | 2018-01-05 | 首都医科大学附属北京安定医院 | 一种双链siRNA分子及其应用 |
| AU2015278699B2 (en) | 2014-06-27 | 2019-10-31 | Rhizen Pharmaceuticals Sa | Substituted chromene derivatives as selective dual inhibitors of PI3 delta and gamma protein kinases |
| US10806748B2 (en) | 2015-04-24 | 2020-10-20 | The Johns Hopkins University | Compositions and methods related to characterizing proviral reservoirs |
| US20180311270A1 (en) * | 2015-10-30 | 2018-11-01 | Norimasa Miura | Rna molecule for repairing dna damage |
| KR102011336B1 (ko) * | 2015-12-31 | 2019-08-16 | 인터올리고 주식회사 | 약물 전달 및 안정화를 위한 복합체 및 그 제조방법 |
| WO2018203553A1 (ja) * | 2017-05-02 | 2018-11-08 | 株式会社ペジィー・ファーマ | 分化細胞の品質改善方法 |
| WO2023128862A1 (en) * | 2021-12-29 | 2023-07-06 | Livius Pte. Ltd. | Method for repairing hair cycle-related genes and method for treating hair cycle-related diseases using mir-520d-5p |
| JP2023149907A (ja) * | 2022-03-31 | 2023-10-16 | 株式会社島津製作所 | 微生物情報の提供方法および微生物検査システム |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2467258A1 (en) * | 2001-11-15 | 2003-05-22 | Kyowa Hakko Kogyo Co., Ltd. | Agent for inducing embryonic stem cell to ectodermal cell, method for obtaining the same and use of the same. |
| AU2003270734A1 (en) | 2002-09-16 | 2004-04-30 | University Of Southern California | Rna-mediated gene modulation |
| JP2006519008A (ja) | 2003-02-10 | 2006-08-24 | 独立行政法人産業技術総合研究所 | 哺乳動物細胞の調節 |
| US9453219B2 (en) * | 2003-05-15 | 2016-09-27 | Mello Biotech Taiwan Co., Ltd. | Cosmetic designs and products using intronic RNA |
| CA2857881A1 (en) * | 2004-11-12 | 2006-12-28 | Asuragen, Inc. | Methods and compositions involving mirna and mirna inhibitor molecules |
| MX2007009417A (es) | 2005-02-04 | 2007-08-17 | Univ Auburn | Sistema de suministro de farmaco de contacto. |
| WO2006112239A1 (ja) | 2005-04-15 | 2006-10-26 | National University Corporation Tottori University | ｈＴＥＲＴ発現調節遺伝子 |
| PL2002003T3 (pl) * | 2005-05-27 | 2016-06-30 | Ospedale San Raffaele Srl | Wektor genetyczny zawierający mi-RNA |
| WO2006137514A1 (ja) | 2005-06-23 | 2006-12-28 | Locomogene, Inc. | シノビオリンの発現もしくは機能阻害物質を有効成分とする癌治療剤、および癌治療剤のスクリーニング方法 |
| BRPI0619794B8 (pt) | 2005-12-13 | 2022-06-14 | Univ Kyoto | Uso de um fator de reprogramação, agente para a preparação de uma célula-tronco pluripotente induzida a partir de uma célula somática e métodos para preparar uma célula- tronco pluripotente induzida método e para preparar uma célula somática e uso de células-tronco pluripotentes induzidas |
| EP2487258B1 (en) * | 2006-01-05 | 2014-10-01 | The Ohio State University Research Foundation | MicroRNA-based methods for the diagnosis of colon, pancreas and stomach cancer |
| CA2648132C (en) | 2006-04-03 | 2019-05-28 | Santaris Pharma A/S | Pharmaceutical composition comprising anti-mirna antisense oligonucleotides |
| EP2217248B1 (en) * | 2007-10-29 | 2016-11-30 | Regulus Therapeutics Inc. | Targeting micrornas for the treatment of liver cancer |
| AU2008297024B2 (en) | 2007-10-31 | 2014-08-28 | Kyoto University | Nuclear reprogramming method |
| JP5558097B2 (ja) | 2007-12-10 | 2014-07-23 | 国立大学法人京都大学 | 効率的な核初期化方法 |
| WO2009082817A1 (en) * | 2007-12-27 | 2009-07-09 | Protiva Biotherapeutics, Inc. | Silencing of polo-like kinase expression using interfering rna |
| WO2009091659A2 (en) * | 2008-01-16 | 2009-07-23 | Shi-Lung Lin | Generation of tumor-free embryonic stem-like pluripotent cells using inducible recombinant rna agents |
| CN101333524B (zh) * | 2008-06-25 | 2010-06-02 | 中山大学 | 一个小分子非编码RNA基因hsa-miR-101及其抗肿瘤用途 |
| CN101392251B (zh) * | 2008-11-03 | 2015-07-22 | 清华大学深圳研究生院 | 能诱导干细胞向成骨细胞分化的微小rna及其应用 |
| JP2010120881A (ja) * | 2008-11-19 | 2010-06-03 | Keio Gijuku | ヒト癌タンパク質ＭＤＭ２とヒト癌抑制タンパク質ｐ５３との相互作用阻害ペプチド及びその使用 |
| CN103189511B (zh) | 2010-07-12 | 2016-10-12 | 国立大学法人鸟取大学 | 利用siRNA导入的新型hiPSC制作法 |
-
2011
- 2011-06-28 CN CN201180043814.8A patent/CN103189511B/zh not_active Expired - Fee Related
- 2011-06-28 EP EP11806631.5A patent/EP2594643B1/en not_active Not-in-force
- 2011-06-28 WO PCT/JP2011/064846 patent/WO2012008301A1/ja not_active Ceased
- 2011-06-28 US US13/809,880 patent/US9476041B2/en not_active Expired - Fee Related
- 2011-06-28 JP JP2011530189A patent/JP5099571B2/ja not_active Expired - Fee Related
- 2011-06-28 WO PCT/JP2011/064847 patent/WO2012008302A1/ja not_active Ceased
- 2011-06-28 EP EP11806632.3A patent/EP2594644B1/en not_active Not-in-force
- 2011-06-28 CN CN201180043810XA patent/CN103097535A/zh active Pending
- 2011-06-28 US US13/809,882 patent/US9790491B2/en not_active Expired - Fee Related
- 2011-06-28 JP JP2011530188A patent/JP5099570B2/ja not_active Expired - Fee Related
-
2012
- 2012-09-14 JP JP2012202508A patent/JP2013046616A/ja active Pending
- 2012-09-14 JP JP2012202509A patent/JP2013034479A/ja active Pending
-
2013
- 2013-12-20 JP JP2013264240A patent/JP5845493B2/ja not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2013046616A5 (https=) | ||
| ZA201902226B (en) | Aav treatment of huntington's disease | |
| JP2013034479A5 (https=) | ||
| WO2014016817A3 (en) | Nucleic acids for down-regulation of gene expression | |
| EA201991369A1 (ru) | Модифицированные направляющие рнк | |
| WO2016183438A8 (en) | Self-targeting genome editing system | |
| WO2016106406A3 (en) | Rna agents for gst-pi gene modulation | |
| MX2016007980A (es) | Acido nucleico que induce acido ribonucleico de interferencia modificado para prevenir una falla en alcanzar el objetivo, y uso del mismo. | |
| MX2015011943A (es) | Acidos ribonucleicos con nucleotidos modificados por 4'-tio y metodos relacionados. | |
| AR100560A1 (es) | Inhibición o regulación por disminución de la glucógeno sintasa mediante la creación de codones de terminación prematuros utilizando oligonucléotidos antisentido | |
| WO2016061232A3 (en) | Multiplexed shrnas and uses thereof | |
| NZ630914A (en) | Methods of treating diabetes and/or promoting survival of pancreatic islets after transplantation | |
| IN2014CN03921A (https=) | ||
| ES2623454T3 (es) | Reducción del contenido de ácidos grasos saturados en semillas de plantas | |
| WO2010017154A3 (en) | Modulation of toll-like receptor 3 expression by antisense oligonucleotides | |
| Yang et al. | Small non-coding RNAs-based bone regulation and targeting therapeutic strategies | |
| AR078848A1 (es) | Tecnologia terapeutica de arn de interferencia dirigido al oncogen pdx -1 en tumores neuroendocrinos donde se expresa pdx-1 | |
| NZ741841A (en) | Antisense oligonucleotides for use in treating alzheimer’s disease | |
| WO2005112636A3 (en) | COMPOSITIONS AND METHODS FOR siRNA INHIBITION OF PRIMATE POLYOMAVIRUS GENES | |
| WO2014153209A8 (en) | Antisense oligonucleotides for treatment of cancer stem cells | |
| JP2012085645A5 (https=) | ||
| JP2010270119A5 (https=) | ||
| JP2010265270A5 (https=) | ||
| WO2015153880A3 (en) | Modulation of hotair and adipogenesis | |
| Aleksandrova et al. | Uses of hydrogel embedded with triple helix micro RNA particle in the treatment of the breast tumors |