JP2012532115A5 - - Google Patents
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- Publication number
- JP2012532115A5 JP2012532115A5 JP2012517923A JP2012517923A JP2012532115A5 JP 2012532115 A5 JP2012532115 A5 JP 2012532115A5 JP 2012517923 A JP2012517923 A JP 2012517923A JP 2012517923 A JP2012517923 A JP 2012517923A JP 2012532115 A5 JP2012532115 A5 JP 2012532115A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- pharmaceutically acceptable
- acceptable salt
- concentration
- finafloxacin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- FYMHQCNFKNMJAV-HOTGVXAUSA-N finafloxacin Chemical compound C12=C(C#N)C(N3C[C@@H]4OCCN[C@H]4C3)=C(F)C=C2C(=O)C(C(=O)O)=CN1C1CC1 FYMHQCNFKNMJAV-HOTGVXAUSA-N 0.000 claims description 17
- 229960002839 finafloxacin Drugs 0.000 claims description 17
- 150000003839 salts Chemical class 0.000 claims description 15
- 208000015181 infectious disease Diseases 0.000 claims description 11
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 claims description 4
- 208000026231 acute otitis externa Diseases 0.000 claims description 4
- 229940121363 anti-inflammatory agent Drugs 0.000 claims description 4
- 239000002260 anti-inflammatory agent Substances 0.000 claims description 4
- 208000022760 infectious otitis media Diseases 0.000 claims description 4
- 230000000699 topical effect Effects 0.000 claims description 4
- 238000009423 ventilation Methods 0.000 claims description 3
- 210000000613 ear canal Anatomy 0.000 claims description 2
- 229910001629 magnesium chloride Inorganic materials 0.000 claims description 2
- MYSWGUAQZAJSOK-UHFFFAOYSA-N ciprofloxacin Chemical compound C12=CC(N3CCNCC3)=C(F)C=C2C(=O)C(C(=O)O)=CN1C1CC1 MYSWGUAQZAJSOK-UHFFFAOYSA-N 0.000 claims 4
- 229960003405 ciprofloxacin Drugs 0.000 claims 2
- FABPRXSRWADJSP-MEDUHNTESA-N moxifloxacin Chemical compound COC1=C(N2C[C@H]3NCCC[C@H]3C2)C(F)=CC(C(C(C(O)=O)=C2)=O)=C1N2C1CC1 FABPRXSRWADJSP-MEDUHNTESA-N 0.000 claims 1
- 229960003702 moxifloxacin Drugs 0.000 claims 1
- 230000002861 ventricular Effects 0.000 claims 1
- 238000000034 method Methods 0.000 description 13
- 210000000959 ear middle Anatomy 0.000 description 2
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22262509P | 2009-07-02 | 2009-07-02 | |
| US61/222,625 | 2009-07-02 | ||
| PCT/US2010/040956 WO2011003091A1 (en) | 2009-07-02 | 2010-07-02 | Compositions comprising finafloxacin and methods for treating ophthalmic, otic, or nasal infections |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015091254A Division JP2015134827A (ja) | 2009-07-02 | 2015-04-28 | 眼、耳または鼻の感染症を処置するためのフィナフロキサシンを含む組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012532115A JP2012532115A (ja) | 2012-12-13 |
| JP2012532115A5 true JP2012532115A5 (enExample) | 2013-05-30 |
| JP5784012B2 JP5784012B2 (ja) | 2015-09-24 |
Family
ID=42752088
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012517923A Active JP5784012B2 (ja) | 2009-07-02 | 2010-07-02 | 眼、耳または鼻の感染症を処置するためのフィナフロキサシンを含む組成物および方法 |
| JP2015091254A Withdrawn JP2015134827A (ja) | 2009-07-02 | 2015-04-28 | 眼、耳または鼻の感染症を処置するためのフィナフロキサシンを含む組成物および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015091254A Withdrawn JP2015134827A (ja) | 2009-07-02 | 2015-04-28 | 眼、耳または鼻の感染症を処置するためのフィナフロキサシンを含む組成物および方法 |
Country Status (17)
| Country | Link |
|---|---|
| US (3) | US8536167B2 (enExample) |
| EP (1) | EP2448587B1 (enExample) |
| JP (2) | JP5784012B2 (enExample) |
| KR (1) | KR101541823B1 (enExample) |
| CN (2) | CN105687111A (enExample) |
| AR (1) | AR077372A1 (enExample) |
| AU (1) | AU2010266120B2 (enExample) |
| BR (1) | BRPI1016257B8 (enExample) |
| CA (1) | CA2765852C (enExample) |
| CL (1) | CL2011003327A1 (enExample) |
| ES (1) | ES2694775T3 (enExample) |
| MX (1) | MX2012000136A (enExample) |
| RU (1) | RU2570731C2 (enExample) |
| TW (1) | TWI460181B (enExample) |
| UY (1) | UY32758A (enExample) |
| WO (1) | WO2011003091A1 (enExample) |
| ZA (1) | ZA201109492B (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2570731C2 (ru) * | 2009-07-02 | 2015-12-10 | Алькон Рисерч, Лтд. | Композиции, включающие финафлоксации, и способы лечения офтальмологических, ушных или назальных инфекций |
| US20150174137A1 (en) * | 2010-06-02 | 2015-06-25 | Alcon Research, Ltd. | Compositions for treating microbial infections |
| US8765725B2 (en) | 2012-05-08 | 2014-07-01 | Aciex Therapeutics, Inc. | Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof |
| PL3517541T3 (pl) | 2012-05-08 | 2020-12-28 | Nicox Ophthalmics, Inc. | Postać polimorficzna propionianu flutykazonu |
| US9504691B2 (en) * | 2012-12-06 | 2016-11-29 | Alcon Research, Ltd. | Finafloxacin suspension compositions |
| US9815865B2 (en) | 2013-01-07 | 2017-11-14 | Nicox Ophthalmics, Inc. | Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof |
| AU2014306781A1 (en) * | 2013-08-12 | 2015-12-24 | Merlion Pharmaceuticals, Pte., Ltd. | Method for treating otic infections after tympanostomy tube placement |
| DE102014115951A1 (de) * | 2014-11-03 | 2016-05-04 | Merlion Pharmaceuticals Pte Ltd. | Zusammensetzungen, die Finafloxacin und Tris enthalten |
| DE102015100068A1 (de) * | 2015-01-06 | 2016-07-07 | Merlion Pharmaceuticals Pte Ltd. | Finafloxacin zur verwendung bei der behandlung von harnwegsinfektionen |
| US11529309B2 (en) * | 2016-04-29 | 2022-12-20 | University Of Houston System | Compositions, methods and kits for treating a contact lens |
| US10282607B2 (en) | 2016-10-28 | 2019-05-07 | The Nielsen Company (Us), Llc | Reducing scale estimate errors in shelf images |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2832535B2 (ja) * | 1989-04-04 | 1998-12-09 | 富山化学工業株式会社 | キノロンカルボン酸またはその塩の可溶化法 |
| US5421818A (en) * | 1993-10-18 | 1995-06-06 | Inner Ear Medical Delivery Systems, Inc. | Multi-functional inner ear treatment and diagnostic system |
| US6156728A (en) | 1996-11-01 | 2000-12-05 | Genentech, Inc. | Treatment of inner ear hair cells |
| DE19652239A1 (de) * | 1996-12-16 | 1998-06-18 | Bayer Ag | Verwendung von 7-(2-Oxa-5,8-diazabicyclo[4.3.0]non-8-yl)-chinolon- und -naphthyridoncarbonsäure-Derivaten zur Therapie von Helicobacter-pylori-Infektionen und den damit assoziierten gastroduodenalen Erkrankungen |
| US6440964B1 (en) * | 1998-09-30 | 2002-08-27 | Alcon Manufacturing, Ltd. | Compositions and methods for treating ophthalmic and otic infections |
| US6509327B1 (en) * | 1998-09-30 | 2003-01-21 | Alcon Manufacturing, Ltd. | Compositions and methods for treating otic, ophthalmic and nasal infections |
| AR020661A1 (es) * | 1998-09-30 | 2002-05-22 | Alcon Lab Inc | Una composicion farmaceutica topica oftalmica, otica o nasal y el uso de la misma para la manufactura de un medicamento |
| US6716830B2 (en) | 1998-09-30 | 2004-04-06 | Alcon, Inc. | Ophthalmic antibiotic compositions containing moxifloxacin |
| JP2006289070A (ja) * | 2005-03-18 | 2006-10-26 | Santen Pharmaceut Co Ltd | キノロン系抗菌化合物含有製品 |
| DK1901749T3 (en) * | 2005-05-18 | 2016-10-24 | Raptor Pharmaceuticals Inc | Aerosolized fluoroquinolones AND USES THEREOF |
| US8158152B2 (en) * | 2005-11-18 | 2012-04-17 | Scidose Llc | Lyophilization process and products obtained thereby |
| RU2570731C2 (ru) * | 2009-07-02 | 2015-12-10 | Алькон Рисерч, Лтд. | Композиции, включающие финафлоксации, и способы лечения офтальмологических, ушных или назальных инфекций |
-
2010
- 2010-07-02 RU RU2012103458/15A patent/RU2570731C2/ru active
- 2010-07-02 AR ARP100102374 patent/AR077372A1/es unknown
- 2010-07-02 CA CA2765852A patent/CA2765852C/en active Active
- 2010-07-02 CN CN201610096682.XA patent/CN105687111A/zh active Pending
- 2010-07-02 EP EP10732580.5A patent/EP2448587B1/en active Active
- 2010-07-02 US US12/829,973 patent/US8536167B2/en active Active
- 2010-07-02 ES ES10732580.5T patent/ES2694775T3/es active Active
- 2010-07-02 JP JP2012517923A patent/JP5784012B2/ja active Active
- 2010-07-02 UY UY32758A patent/UY32758A/es not_active Application Discontinuation
- 2010-07-02 CN CN2010800298152A patent/CN102470139A/zh active Pending
- 2010-07-02 MX MX2012000136A patent/MX2012000136A/es active IP Right Grant
- 2010-07-02 KR KR1020127001627A patent/KR101541823B1/ko active Active
- 2010-07-02 BR BRPI1016257A patent/BRPI1016257B8/pt active IP Right Grant
- 2010-07-02 WO PCT/US2010/040956 patent/WO2011003091A1/en not_active Ceased
- 2010-07-02 TW TW99121805A patent/TWI460181B/zh not_active IP Right Cessation
- 2010-07-02 AU AU2010266120A patent/AU2010266120B2/en active Active
-
2011
- 2011-12-22 ZA ZA2011/09492A patent/ZA201109492B/en unknown
- 2011-12-28 CL CL2011003327A patent/CL2011003327A1/es unknown
-
2013
- 2013-08-15 US US13/967,897 patent/US9119859B2/en active Active
-
2015
- 2015-04-28 JP JP2015091254A patent/JP2015134827A/ja not_active Withdrawn
- 2015-07-27 US US14/809,878 patent/US9993483B2/en active Active
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