JP2012526844A5 - - Google Patents
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- JP2012526844A5 JP2012526844A5 JP2012511013A JP2012511013A JP2012526844A5 JP 2012526844 A5 JP2012526844 A5 JP 2012526844A5 JP 2012511013 A JP2012511013 A JP 2012511013A JP 2012511013 A JP2012511013 A JP 2012511013A JP 2012526844 A5 JP2012526844 A5 JP 2012526844A5
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- JP
- Japan
- Prior art keywords
- nifedipine
- composition
- item
- nitrosonifedipine
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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| EP2715350B1 (en) | 2011-05-23 | 2017-09-27 | Yeda Research and Development Co. Ltd. | Use of akt phosphorylation as a biomarker for prognosing neurodegenerative diseases and treating same |
| CA2838562A1 (en) * | 2011-08-08 | 2013-02-14 | Eugenia Wang | Biomarker for alzheimer's disease and/or mild cognitively impairment, and use thereof |
| US10653650B2 (en) | 2011-12-13 | 2020-05-19 | Io Therapeutics, Inc. | Treatment of diseases by concurrently eliciting remyelination effects and immunomodulatory effects using selective RXR agonists |
| MX352727B (es) | 2011-12-13 | 2017-12-06 | Dartmouth College | Tratamiento de trastorno autoinmune al usar agonistas de rxr. |
| KR20150027800A (ko) * | 2012-06-15 | 2015-03-12 | 고에키 자이단 호징 센탄 이료 신코 자이단 | 경도 인지 장해의 예방 및/또는 치료제 |
| US8901305B2 (en) * | 2012-07-31 | 2014-12-02 | Bristol-Myers Squibb Company | Aryl lactam kinase inhibitors |
| US20150045353A1 (en) * | 2013-08-09 | 2015-02-12 | Neurogenetic Pharmaceuticals, Inc. | Formulations containing gamma secretase modulators, methods for preparation and delivery thereof |
| WO2017075607A1 (en) | 2015-10-31 | 2017-05-04 | Io Therapeutics, Inc. | Treatment of nervous system disorders using combinations of pxr agonists and thyroid hormones |
| KR20180121983A (ko) | 2016-03-10 | 2018-11-09 | 아이오 테라퓨틱스, 인크. | Rxr 작용제 및 갑상선 호르몬의 조합을 사용한 근육 질환의 치료 |
| CA3016876C (en) | 2016-03-10 | 2021-12-28 | Io Therapeutics, Inc. | Treatment of autoimmune diseases with combinations of rxr agonists and thyroid hormones |
| US11517549B2 (en) * | 2017-09-20 | 2022-12-06 | Io Therapeutics, Inc. | Treatment of disease with esters of selective RXR agonists |
| US10966950B2 (en) | 2019-06-11 | 2021-04-06 | Io Therapeutics, Inc. | Use of an RXR agonist in treating HER2+ cancers |
| MX2024006978A (es) | 2021-12-07 | 2024-07-19 | Io Therapeutics Inc | Uso de un agonista de rxr y taxanos en el tratamiento de cáncer her2+. |
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| DE2126533A1 (de) * | 1971-05-28 | 1972-12-14 | Merck Patent Gmbh, 6100 Darmstadt | Verfahren zur Herstellung pharma zeutischer Zubereitungen |
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| IT1270594B (it) * | 1994-07-07 | 1997-05-07 | Recordati Chem Pharm | Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida |
| EP2311806A3 (en) * | 1996-01-29 | 2011-08-10 | The United States of America, Represented by the Secretary, Department of Health and Human Services | Dihydropyridine-, pyridine-, benzopyranone- and triazoloquinazoline derivatives, their preparation and their use as adenosine receptor antagonists |
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| US6558650B1 (en) * | 1998-04-08 | 2003-05-06 | Oregon Health And Science University | Enhancement of cellular gallium uptake |
| CA2525970C (en) * | 2003-05-15 | 2011-03-22 | Roskamp Research, Llc | Use of nilvadipine for reducing amyloid deposition, amyloid neurotoxicity and microgliosis |
| WO2005051389A1 (en) * | 2003-11-21 | 2005-06-09 | Memory Pharmaceuticals Corporation | Using of (+)-isopropyl 2-methoxyethyl 4-(2-chloro-3-cyano-phenyl)-1,4-dihydro-2,6-dymethyl-pyridine-3,5-dicarboxylate in the treatment of memory disorders |
| WO2006040153A2 (en) * | 2004-10-13 | 2006-04-20 | Ablynx N.V. | Single domain camelide anti -amyloid beta antibodies and polypeptides comprising the same for the treatment and diagnosis of degenarative neural diseases such as alzheimer's disease |
| EP1874311B1 (en) * | 2005-04-15 | 2011-10-05 | Research & Innovation S.p.A. | A method for preventing, delaying or reverting abnormal amyloid deposition |
| WO2006116499A1 (en) * | 2005-04-26 | 2006-11-02 | Microbia, Inc. | 4-biarylyl-1-phenylazetidin-2-one glucuronide derivatives for hypercholesterolemia |
| JP2007091664A (ja) * | 2005-09-29 | 2007-04-12 | Univ Of Tokushima | 細胞膜保護剤 |
| US20090286879A1 (en) * | 2005-12-02 | 2009-11-19 | Kiyoshi Hashizume | Preventive or Therapeutic Drug for Alzheimer-Type Dementia |
| US20100029654A1 (en) * | 2006-03-23 | 2010-02-04 | Mount Sinai School Of Medicine | Cardiovascular compositions and use of the same for the treatment of alzheimer's disease |
| CA2648243C (en) * | 2006-04-11 | 2015-12-22 | Shaker A. Mousa | Nanoparticle and polymer formulations for thyroid hormone analogs, antagonists, and formulations thereof |
| JP2009073759A (ja) * | 2007-09-20 | 2009-04-09 | Univ Of Tokushima | Ｉｃａｍ−１発現抑制剤 |
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- 2010-05-13 AU AU2010249015A patent/AU2010249015A1/en not_active Abandoned
- 2010-05-13 EP EP10775535A patent/EP2429992A4/en not_active Withdrawn
- 2010-05-13 JP JP2012511013A patent/JP2012526844A/ja active Pending
- 2010-05-13 CA CA2761298A patent/CA2761298A1/en not_active Abandoned
- 2010-05-13 WO PCT/US2010/034721 patent/WO2010132671A1/en not_active Ceased
- 2010-05-13 US US12/779,345 patent/US20100292281A1/en not_active Abandoned
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