JP2012523430A5 - - Google Patents
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- Publication number
- JP2012523430A5 JP2012523430A5 JP2012504880A JP2012504880A JP2012523430A5 JP 2012523430 A5 JP2012523430 A5 JP 2012523430A5 JP 2012504880 A JP2012504880 A JP 2012504880A JP 2012504880 A JP2012504880 A JP 2012504880A JP 2012523430 A5 JP2012523430 A5 JP 2012523430A5
- Authority
- JP
- Japan
- Prior art keywords
- degenerative disorder
- piperzine
- diol
- prodrug
- solvate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16810109P | 2009-04-09 | 2009-04-09 | |
| US61/168,101 | 2009-04-09 | ||
| PCT/US2010/030470 WO2010118282A1 (en) | 2009-04-09 | 2010-04-09 | Methods for preventing and/or treating degenerative disorders of the central nervous system |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012523430A JP2012523430A (ja) | 2012-10-04 |
| JP2012523430A5 true JP2012523430A5 (enExample) | 2013-05-16 |
| JP5634498B2 JP5634498B2 (ja) | 2014-12-03 |
Family
ID=42934882
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012504880A Active JP5634498B2 (ja) | 2009-04-09 | 2010-04-09 | 中枢神経系の変性障害の予防および／または治療方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8304429B2 (enExample) |
| EP (1) | EP2416655B1 (enExample) |
| JP (1) | JP5634498B2 (enExample) |
| CN (1) | CN102448306B (enExample) |
| AU (1) | AU2010233187B2 (enExample) |
| BR (1) | BRPI1015472A2 (enExample) |
| CA (1) | CA2758187C (enExample) |
| ES (1) | ES2505243T3 (enExample) |
| IL (1) | IL215584A (enExample) |
| NZ (1) | NZ595630A (enExample) |
| WO (1) | WO2010118282A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102625661B (zh) * | 2009-04-09 | 2015-05-27 | 阿米库斯治疗学公司 | 用于预防和/或治疗溶酶体贮积失调的方法 |
| RU2608520C2 (ru) | 2009-10-19 | 2017-01-19 | Амикус Терапьютикс, Инк. | Новые композиции для предупреждения и/или лечения лизосомных болезней накопления |
| KR101880411B1 (ko) * | 2009-10-19 | 2018-07-19 | 아미쿠스 세라퓨틱스, 인코포레이티드 | 중추신경계의 퇴행성 질환을 예방 및/또는 치료하는 신규 조성물 |
| WO2012068405A2 (en) | 2010-11-17 | 2012-05-24 | Isis Pharmaceuticals, Inc. | Modulation of alpha synuclein expression |
| WO2013070981A2 (en) * | 2011-11-08 | 2013-05-16 | University Of Central Florida Research Foundation, Inc. | Treating er stress related disorders by stabilizing intracellular calcium homeostasis |
| US9155695B2 (en) | 2013-03-14 | 2015-10-13 | Medtronic, Inc. | Injectable ropinirole compositions and methods for making and using same |
| WO2015095963A1 (en) | 2013-12-23 | 2015-07-02 | Alectos Therapeutics Inc. | Glucocerebrosidase modulators and uses thereof |
| GB201512203D0 (en) | 2015-07-13 | 2015-08-19 | Lundbeck & Co As H | Agents,uses and methods |
| US10300155B2 (en) | 2015-12-31 | 2019-05-28 | Washington University | Alpha-synuclein ligands |
| CA3036511A1 (en) * | 2016-09-12 | 2018-03-15 | Steven Hoffman | Compositions for treating dementia |
| US10889635B2 (en) | 2016-11-15 | 2021-01-12 | H. Lundbeck A/S | Agents, uses and methods for the treatment of synucleinopathy |
| MX2020007433A (es) | 2018-01-12 | 2020-09-14 | Bristol Myers Squibb Co | Oligonucleotidos antisentido que actuan sobre alfa-sinucleina, y usos de estos. |
| EA202091693A1 (ru) | 2018-01-12 | 2021-04-14 | Бристол-Маерс Сквибб Компани | Антисмысловые олигонуклеотиды, целенаправленно воздействующие на альфа-синуклеин, и их применения |
| CN119606967B (zh) * | 2024-12-13 | 2025-09-05 | 合肥工业大学 | 氯雷他定在制备用于预防和治疗血管钙化药物中的应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0749423B1 (en) * | 1994-03-09 | 2003-06-18 | Novo Nordisk A/S | Piperidines and pyrrolidines |
| WO2002076440A2 (en) * | 2001-03-23 | 2002-10-03 | Elan Pharmaceuticals, Inc. | Methods of treating alzheimer's disease with piperidin derivates |
| US6770625B2 (en) * | 2001-09-07 | 2004-08-03 | Nobex Corporation | Pharmaceutical compositions of calcitonin drug-oligomer conjugates and methods of treating diseases therewith |
| US6670625B1 (en) * | 2002-06-18 | 2003-12-30 | Ge Medical Systems Global Technology Company, Llc | Method and apparatus for correcting multipole aberrations of an electron beam in an EBT scanner |
| JP2006507359A (ja) * | 2002-10-28 | 2006-03-02 | ノボ・ノルデイスク・エー／エス | 心循環器疾患の治療のためのグリコーゲンホスホリラーゼ阻害剤の使用 |
| WO2006133446A2 (en) * | 2005-06-08 | 2006-12-14 | Amicus Therapeutics, Inc. | Treatment of cns disorders associated with mutations in genes encoding lysosomal enzymes |
| JP5303458B2 (ja) | 2006-06-23 | 2013-10-02 | アミークス セラピューティックス インコーポレイテッド | β−グルコセレブロシダーゼの活性増強による神経学的疾患の治療方法 |
| US20080009156A1 (en) | 2006-07-10 | 2008-01-10 | Malin Glen K | System and method for bonding coaxial cable |
| CN102625661B (zh) * | 2009-04-09 | 2015-05-27 | 阿米库斯治疗学公司 | 用于预防和/或治疗溶酶体贮积失调的方法 |
-
2010
- 2010-04-09 ES ES10762468.6T patent/ES2505243T3/es active Active
- 2010-04-09 CA CA2758187A patent/CA2758187C/en not_active Expired - Fee Related
- 2010-04-09 WO PCT/US2010/030470 patent/WO2010118282A1/en not_active Ceased
- 2010-04-09 NZ NZ595630A patent/NZ595630A/xx not_active IP Right Cessation
- 2010-04-09 AU AU2010233187A patent/AU2010233187B2/en not_active Ceased
- 2010-04-09 CN CN201080024142.1A patent/CN102448306B/zh not_active Expired - Fee Related
- 2010-04-09 EP EP10762468.6A patent/EP2416655B1/en active Active
- 2010-04-09 BR BRPI1015472A patent/BRPI1015472A2/pt not_active Application Discontinuation
- 2010-04-09 US US12/757,144 patent/US8304429B2/en not_active Expired - Fee Related
- 2010-04-09 JP JP2012504880A patent/JP5634498B2/ja active Active
-
2011
- 2011-10-06 IL IL215584A patent/IL215584A/en not_active IP Right Cessation
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