JP2012521404A5 - - Google Patents
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- Publication number
- JP2012521404A5 JP2012521404A5 JP2012501410A JP2012501410A JP2012521404A5 JP 2012521404 A5 JP2012521404 A5 JP 2012521404A5 JP 2012501410 A JP2012501410 A JP 2012501410A JP 2012501410 A JP2012501410 A JP 2012501410A JP 2012521404 A5 JP2012521404 A5 JP 2012521404A5
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- JP
- Japan
- Prior art keywords
- los
- composition
- composition according
- item
- motomeko
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000004044 tetrasaccharides Chemical class 0.000 claims description 10
- 150000001720 carbohydrates Chemical class 0.000 claims description 9
- 230000002163 immunogen Effects 0.000 claims description 8
- 108010078791 Carrier Proteins Proteins 0.000 claims description 6
- 102000014914 Carrier Proteins Human genes 0.000 claims description 6
- 102000004190 Enzymes Human genes 0.000 claims description 6
- 108090000790 Enzymes Proteins 0.000 claims description 6
- 230000000694 effects Effects 0.000 claims description 6
- 241000588650 Neisseria meningitidis Species 0.000 claims description 5
- 241000124008 Mammalia Species 0.000 claims description 4
- 239000002671 adjuvant Substances 0.000 claims description 4
- 230000028993 immune response Effects 0.000 claims description 4
- AZDRQVAHHNSJOQ-UHFFFAOYSA-N alumane Chemical class [AlH3] AZDRQVAHHNSJOQ-UHFFFAOYSA-N 0.000 claims description 3
- 108010071134 CRM197 (non-toxic variant of diphtheria toxin) Proteins 0.000 claims description 2
- 102100037840 Dehydrogenase/reductase SDR family member 2, mitochondrial Human genes 0.000 claims description 2
- 101710188053 Protein D Proteins 0.000 claims description 2
- 101710132893 Resolvase Proteins 0.000 claims description 2
- 108010031133 Transferrin-Binding Protein A Proteins 0.000 claims description 2
- ILRRQNADMUWWFW-UHFFFAOYSA-K aluminium phosphate Chemical compound O1[Al]2OP1(=O)O2 ILRRQNADMUWWFW-UHFFFAOYSA-K 0.000 claims description 2
- 229960003983 diphtheria toxoid Drugs 0.000 claims description 2
- 101150002054 galE gene Proteins 0.000 claims description 2
- 229930182830 galactose Natural products 0.000 claims description 2
- GZQKNULLWNGMCW-PWQABINMSA-N lipid A (E. coli) Chemical group O1[C@H](CO)[C@@H](OP(O)(O)=O)[C@H](OC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC)[C@@H](NC(=O)C[C@@H](CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)[C@@H]1OC[C@@H]1[C@@H](O)[C@H](OC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H](NC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H](OP(O)(O)=O)O1 GZQKNULLWNGMCW-PWQABINMSA-N 0.000 claims description 2
- 239000012528 membrane Substances 0.000 claims description 2
- 108090000623 proteins and genes Proteins 0.000 claims description 2
- 102000004169 proteins and genes Human genes 0.000 claims description 2
- 229960000814 tetanus toxoid Drugs 0.000 claims description 2
- STCOOQWBFONSKY-UHFFFAOYSA-N tributyl phosphate Chemical compound CCCCOP(=O)(OCCCC)OCCCC STCOOQWBFONSKY-UHFFFAOYSA-N 0.000 claims description 2
- 125000003275 alpha amino acid group Chemical group 0.000 description 7
- 229920001184 polypeptide Polymers 0.000 description 6
- 102000004196 processed proteins & peptides Human genes 0.000 description 6
- 108090000765 processed proteins & peptides Proteins 0.000 description 6
- 150000001413 amino acids Chemical class 0.000 description 3
- 239000012634 fragment Substances 0.000 description 3
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 2
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 230000021615 conjugation Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16299609P | 2009-03-24 | 2009-03-24 | |
| US61/162,996 | 2009-03-24 | ||
| PCT/IB2010/000735 WO2010109325A2 (en) | 2009-03-24 | 2010-03-24 | Combinations including pneumococcal serotype 14 saccharide |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015121897A Division JP2015163651A (ja) | 2009-03-24 | 2015-06-17 | 肺炎球菌血清型１４の糖を含む組み合わせ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012521404A JP2012521404A (ja) | 2012-09-13 |
| JP2012521404A5 true JP2012521404A5 (https=) | 2013-05-09 |
| JP5806204B2 JP5806204B2 (ja) | 2015-11-10 |
Family
ID=42352288
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012501410A Expired - Fee Related JP5806204B2 (ja) | 2009-03-24 | 2010-03-24 | 肺炎球菌血清型１４の糖を含む組み合わせ |
| JP2015121897A Ceased JP2015163651A (ja) | 2009-03-24 | 2015-06-17 | 肺炎球菌血清型１４の糖を含む組み合わせ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015121897A Ceased JP2015163651A (ja) | 2009-03-24 | 2015-06-17 | 肺炎球菌血清型１４の糖を含む組み合わせ |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20120064104A1 (https=) |
| EP (1) | EP2411044A2 (https=) |
| JP (2) | JP5806204B2 (https=) |
| CN (1) | CN102421449A (https=) |
| AU (1) | AU2010227221B2 (https=) |
| CA (1) | CA2756398A1 (https=) |
| NZ (1) | NZ595223A (https=) |
| RU (2) | RU2549438C2 (https=) |
| WO (1) | WO2010109325A2 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ515935A (en) | 1999-05-19 | 2004-01-30 | Chiron S | Combination Neisserial compositions and vaccines for the prevention of infections due to Neisseria bacteria such as meningococcal meningitis |
| GB0316560D0 (en) | 2003-07-15 | 2003-08-20 | Chiron Srl | Vesicle filtration |
| CN103533953A (zh) | 2011-05-17 | 2014-01-22 | 葛兰素史密丝克莱恩生物有限公司 | 针对肺炎链球菌的疫苗 |
| CN104428008B (zh) | 2012-05-24 | 2020-10-09 | 美国政府(由卫生和人类服务部的部长所代表) | 多价脑膜炎球菌缀合物及制备缀合物的方法 |
| AU2013276083B2 (en) * | 2012-06-14 | 2018-04-05 | Institut Pasteur | Vaccines for serogroup X meningococcus |
| WO2014016152A1 (en) | 2012-07-27 | 2014-01-30 | Institut National De La Sante Et De La Recherche Medicale | Cd147 as receptor for pilus-mediated adhesion of meningococci to vascular endothelia |
| CN110859957B (zh) * | 2014-01-21 | 2024-04-12 | 辉瑞公司 | 包含缀合荚膜糖抗原的免疫原性组合物及其用途 |
| US20150344530A1 (en) * | 2014-05-29 | 2015-12-03 | Subhash V. Kapre | Synthetic Peptides as Carriers for Conjugation with Polysaccharides |
| US9107906B1 (en) | 2014-10-28 | 2015-08-18 | Adma Biologics, Inc. | Compositions and methods for the treatment of immunodeficiency |
| US10738338B2 (en) | 2016-10-18 | 2020-08-11 | The Research Foundation for the State University | Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate |
| US10259865B2 (en) | 2017-03-15 | 2019-04-16 | Adma Biologics, Inc. | Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection |
| WO2023132795A2 (en) * | 2022-01-05 | 2023-07-13 | National University Of Singapore | Modified bacterial glycans and conjugates thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060057160A1 (en) * | 2002-08-02 | 2006-03-16 | Ralph Biemans | Vaccine composition |
| KR101515078B1 (ko) * | 2005-12-22 | 2015-04-24 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 백신 |
-
2010
- 2010-03-24 CN CN2010800212325A patent/CN102421449A/zh active Pending
- 2010-03-24 JP JP2012501410A patent/JP5806204B2/ja not_active Expired - Fee Related
- 2010-03-24 AU AU2010227221A patent/AU2010227221B2/en not_active Ceased
- 2010-03-24 RU RU2011142747/15A patent/RU2549438C2/ru not_active IP Right Cessation
- 2010-03-24 NZ NZ595223A patent/NZ595223A/en not_active IP Right Cessation
- 2010-03-24 US US13/260,550 patent/US20120064104A1/en not_active Abandoned
- 2010-03-24 CA CA2756398A patent/CA2756398A1/en not_active Abandoned
- 2010-03-24 WO PCT/IB2010/000735 patent/WO2010109325A2/en not_active Ceased
- 2010-03-24 EP EP10714681A patent/EP2411044A2/en not_active Withdrawn
-
2014
- 2014-05-30 RU RU2014122163/15A patent/RU2014122163A/ru not_active Application Discontinuation
-
2015
- 2015-06-17 JP JP2015121897A patent/JP2015163651A/ja not_active Ceased
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