JP2012521364A - 概日リズムを調整する方法 - Google Patents

概日リズムを調整する方法 Download PDF

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JP2012521364A
JP2012521364A JP2012501029A JP2012501029A JP2012521364A JP 2012521364 A JP2012521364 A JP 2012521364A JP 2012501029 A JP2012501029 A JP 2012501029A JP 2012501029 A JP2012501029 A JP 2012501029A JP 2012521364 A JP2012521364 A JP 2012521364A
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ampk
circadian rhythm
circadian
agonist
subject
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JP2012521364A5 (enExample
Inventor
ロナルド エバンス，
カッジャ エー． ラミア，
リューベン ジェイ． シャー，
ルチアーノ ディタッチオ，
サチダナンダ パンダ，
ウマ エム． サチデバ，
クレイグ ビー． トンプソン，
Original Assignee
ザ ソーク インスティテュート フォー バイオロジカル スタディーズ
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Publication of JP2012521364A publication Critical patent/JP2012521364A/ja
Publication of JP2012521364A5 publication Critical patent/JP2012521364A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2264—Obesity-gene products, e.g. leptin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2864—Sleep disorders

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Obesity (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Anesthesiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2012501029A 2009-03-20 2010-03-22 概日リズムを調整する方法 Pending JP2012521364A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16222509P 2009-03-20 2009-03-20
US61/162,225 2009-03-20
PCT/US2010/028155 WO2010108179A1 (en) 2009-03-20 2010-03-22 Methods for modulating circadian rythms

Publications (2)

Publication Number Publication Date
JP2012521364A true JP2012521364A (ja) 2012-09-13
JP2012521364A5 JP2012521364A5 (enExample) 2013-05-09

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ID=42740034

Family Applications (1)

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JP2012501029A Pending JP2012521364A (ja) 2009-03-20 2010-03-22 概日リズムを調整する方法

Country Status (6)

Country Link
US (1) US20120264796A1 (enExample)
EP (1) EP2409152A4 (enExample)
JP (1) JP2012521364A (enExample)
AU (1) AU2010226417A1 (enExample)
CA (1) CA2753876A1 (enExample)
WO (1) WO2010108179A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012521198A (ja) * 2009-03-20 2012-09-13 ザ ソーク インスティテュート フォー バイオロジカル スタディーズ 代謝リズムおよび概日リズムを調整する方法

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140186306A1 (en) * 2012-09-28 2014-07-03 Paul Ronald Plante Novel ampk agonist compositions and methods of use
US10572904B2 (en) 2017-03-29 2020-02-25 International Business Machines Corporation Micro circadian rhythms driven dynamic product offering adjustment

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070213295A1 (en) * 2006-01-16 2007-09-13 The Board Of Regents Of The University Of Texas System Methods and compositions for inducing torpor in a subject
US20080188457A1 (en) * 2007-02-02 2008-08-07 Braincells, Inc. Modulation of Neurogenesis with Biguanides and GSK3-beta Agents

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3466215D1 (en) * 1983-05-18 1987-10-22 Univ Monash The use of melatonin for the manufacture of a medicament
US20060147947A1 (en) * 2002-12-04 2006-07-06 Javier Apfeld AMPK pathway components
CA2551637A1 (en) * 2003-12-24 2005-07-14 Sepracor Inc. Melatonin combination therapy for improving sleep quality
TWI428767B (zh) * 2006-06-26 2014-03-01 Ibm 最佳化配置系統參數集之方法，程式及裝置
KR100766273B1 (ko) * 2006-10-23 2007-10-15 주식회사 녹십자 아디포넥틴을 유효 성분으로 포함하는 프라더-윌리 증후군소아용 수면 장애 치료제
JP2011507970A (ja) * 2007-12-28 2011-03-10 ザ ソーク インスティテュート フォー バイオロジカル スタディーズ 筋肉の能力および緊張を向上させるための方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070213295A1 (en) * 2006-01-16 2007-09-13 The Board Of Regents Of The University Of Texas System Methods and compositions for inducing torpor in a subject
US20080188457A1 (en) * 2007-02-02 2008-08-07 Braincells, Inc. Modulation of Neurogenesis with Biguanides and GSK3-beta Agents

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JPN6014015802; Ａｍ．　Ｊ．　Ｐｈｙｓｉｏｌ．　Ｅｎｄｏｃｒｉｎｏｌ．　Ｍｅｔａｂ．，　２００８，　Ｖｏｌ．２９５，　Ｎｏ．５，　ｐｐ．Ｅ１０３２-Ｅ１０３７ *
JPN6014015804; Ｊ．　Ｂｉｏｌ．　Ｃｈｅｍ．，　２００７，　Ｖｏｌ．２８２，　Ｎｏ．２９，　ｐｐ．２０７９４-２０７９８ *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012521198A (ja) * 2009-03-20 2012-09-13 ザ ソーク インスティテュート フォー バイオロジカル スタディーズ 代謝リズムおよび概日リズムを調整する方法

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Publication number Publication date
EP2409152A1 (en) 2012-01-25
AU2010226417A1 (en) 2011-10-13
EP2409152A4 (en) 2012-10-17
CA2753876A1 (en) 2010-09-23
WO2010108179A1 (en) 2010-09-23
US20120264796A1 (en) 2012-10-18

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