JP2012520081A - Sparc血管新生ドメイン及び使用方法 - Google Patents

Sparc血管新生ドメイン及び使用方法 Download PDF

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Publication number
JP2012520081A
JP2012520081A JP2011554211A JP2011554211A JP2012520081A JP 2012520081 A JP2012520081 A JP 2012520081A JP 2011554211 A JP2011554211 A JP 2011554211A JP 2011554211 A JP2011554211 A JP 2011554211A JP 2012520081 A JP2012520081 A JP 2012520081A
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JP
Japan
Prior art keywords
tumor
seq
sparc
polypeptide
angiogenesis
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Pending
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JP2011554211A
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English (en)
Japanese (ja)
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JP2012520081A5 (enExample
Inventor
チェウ、ヴォン
ナウアー、ダニエル
デサイ、ニール
Original Assignee
アブラクシス バイオサイエンス リミテッド ライアビリティー カンパニー
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Application filed by アブラクシス バイオサイエンス リミテッド ライアビリティー カンパニー filed Critical アブラクシス バイオサイエンス リミテッド ライアビリティー カンパニー
Publication of JP2012520081A publication Critical patent/JP2012520081A/ja
Publication of JP2012520081A5 publication Critical patent/JP2012520081A5/ja
Pending legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2011554211A 2009-03-11 2010-03-11 Sparc血管新生ドメイン及び使用方法 Pending JP2012520081A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15932209P 2009-03-11 2009-03-11
US61/159,322 2009-03-11
PCT/US2010/027041 WO2010105097A2 (en) 2009-03-11 2010-03-11 Sparc angiogenic domain and methods of use

Publications (2)

Publication Number Publication Date
JP2012520081A true JP2012520081A (ja) 2012-09-06
JP2012520081A5 JP2012520081A5 (enExample) 2013-05-02

Family

ID=42729116

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011554211A Pending JP2012520081A (ja) 2009-03-11 2010-03-11 Sparc血管新生ドメイン及び使用方法

Country Status (13)

Country Link
US (2) US20120087910A1 (enExample)
EP (1) EP2405932A4 (enExample)
JP (1) JP2012520081A (enExample)
KR (2) KR20110139256A (enExample)
CN (2) CN103724417A (enExample)
AU (1) AU2010224031B2 (enExample)
BR (1) BRPI1009457A2 (enExample)
CA (1) CA2755109A1 (enExample)
IL (2) IL215089A0 (enExample)
MX (1) MX2011009478A (enExample)
NZ (1) NZ595528A (enExample)
WO (1) WO2010105097A2 (enExample)
ZA (1) ZA201107415B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2011224154A1 (en) * 2010-03-11 2012-09-27 Abraxis Bioscience, Llc SPARC angiogenic domain and methods of use
US8628554B2 (en) 2010-06-13 2014-01-14 Virender K. Sharma Intragastric device for treating obesity
US9526648B2 (en) 2010-06-13 2016-12-27 Synerz Medical, Inc. Intragastric device for treating obesity
US10010439B2 (en) 2010-06-13 2018-07-03 Synerz Medical, Inc. Intragastric device for treating obesity
US10420665B2 (en) 2010-06-13 2019-09-24 W. L. Gore & Associates, Inc. Intragastric device for treating obesity
US10779980B2 (en) 2016-04-27 2020-09-22 Synerz Medical, Inc. Intragastric device for treating obesity
CN120361186A (zh) * 2025-04-15 2025-07-25 北京大学口腔医学院 一种促进血管生成和组织再生的药物组合物及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002000677A1 (en) * 2000-06-07 2002-01-03 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies
WO2006112930A2 (en) * 2005-02-18 2006-10-26 Abraxis Bioscience, Inc. Q3 sparc deletion mutant and uses thereof
JP5590882B2 (ja) * 2006-06-26 2014-09-17 ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア 化学療法増感剤としてのシステインに富む酸性分泌タンパク質(sparc)
AU2008240117B2 (en) * 2007-04-13 2013-12-05 Abraxis Bioscience, Llc SPARC and methods of use thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JPN6014032394; KUAUER D et al: 'Identification of the albumin-binding domain and the angiogenic domen of SPARC' European Journal of Cancer supplement, vol.7, no.2, 20090901, p.87-88 *
JPN6014032397; KNAUER D. et al: 'Albumin-Binding and Angiogenic Domains of SPARC Located at Its C-Terminus' Cancer Research 69, 24, supplement 3, 20091215 *
JPN6014032400; JENDRASCHAK E. et al: 'Regulations of angiogenesis by SPARC and angiostatin: implications for tumor cell biology' seminars in CANCER BIOLOGY 7, 1996, p.139-146 *

Also Published As

Publication number Publication date
MX2011009478A (es) 2011-11-18
KR20110139256A (ko) 2011-12-28
CN103724417A (zh) 2014-04-16
AU2010224031B2 (en) 2013-05-02
EP2405932A2 (en) 2012-01-18
US20140094416A1 (en) 2014-04-03
IL228795A0 (en) 2013-12-31
WO2010105097A2 (en) 2010-09-16
IL215089A0 (en) 2011-11-30
WO2010105097A8 (en) 2011-05-26
AU2010224031A2 (en) 2011-10-20
NZ595528A (en) 2013-10-25
US20120087910A1 (en) 2012-04-12
BRPI1009457A2 (pt) 2016-03-01
CN102482334A (zh) 2012-05-30
EP2405932A4 (en) 2012-08-22
ZA201107415B (en) 2012-06-27
WO2010105097A3 (en) 2010-11-04
KR20130043242A (ko) 2013-04-29
CA2755109A1 (en) 2010-09-16
AU2010224031A1 (en) 2011-10-06

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