JP2012514006A - 3.1.0二環式GlyT1阻害剤ならびにその作製および使用の方法 - Google Patents
3.1.0二環式GlyT1阻害剤ならびにその作製および使用の方法 Download PDFInfo
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- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US14103008P | 2008-12-29 | 2008-12-29 | |
| US61/141,030 | 2008-12-29 | ||
| PCT/US2009/069716 WO2010078348A1 (en) | 2008-12-29 | 2009-12-29 | 3.1.0 bicyclic glyt1 inhibitors and methods of making and using same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012514006A true JP2012514006A (ja) | 2012-06-21 |
| JP2012514006A5 JP2012514006A5 (OSRAM) | 2013-01-31 |
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Family Applications (1)
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| JP2011543717A Pending JP2012514006A (ja) | 2008-12-29 | 2009-12-29 | 3.1.0二環式GlyT1阻害剤ならびにその作製および使用の方法 |
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| US (1) | US8497289B2 (OSRAM) |
| EP (1) | EP2381941A4 (OSRAM) |
| JP (1) | JP2012514006A (OSRAM) |
| KR (1) | KR20110117087A (OSRAM) |
| CN (1) | CN102271677A (OSRAM) |
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| RU (1) | RU2011124709A (OSRAM) |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2017514871A (ja) * | 2014-05-06 | 2017-06-08 | ノースウェスタン ユニバーシティ | Nmdar調節化合物の組合せ |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9012489B2 (en) * | 2011-08-03 | 2015-04-21 | Boehringer Ingelheim International Gmbh | Phenyl-3-aza-bicyclo[3.1.0]hex-3-yl-methanones and the use thereof as medicament |
| US9987242B2 (en) | 2015-05-05 | 2018-06-05 | Northwestern University | Treatment of Levodopa-induced Dyskinesias |
| AU2020266566B2 (en) * | 2019-05-01 | 2025-11-06 | Boehringer Ingelheim International Gmbh | Solid forms of a GlyT1 inhibitor |
| AU2021324376A1 (en) | 2020-08-13 | 2023-02-02 | Boehringer Ingelheim International Gmbh | Treatment of cognitive impairement associated with schizophrenia |
| MX2023004293A (es) | 2020-10-13 | 2023-05-03 | Boehringer Ingelheim Int | Proceso de reelaboracion. |
| IL318673A (en) | 2022-08-09 | 2025-03-01 | Xizang Haisco Pharmaceutical Co Ltd | PDE4B inhibitor and its use |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005037216A2 (en) * | 2003-10-14 | 2005-04-28 | Pfizer Products Inc. | Bicyclic [3.1.0] derivatives as glycine transporter inhibitors |
| WO2006067529A1 (en) * | 2004-12-21 | 2006-06-29 | Merck Sharp & Dohme Limited | Piperidine and azetidine derivatives as glyt1 inhibitors |
| WO2007060484A1 (en) * | 2005-11-25 | 2007-05-31 | Merck Sharp & Dohme Limited | Azetidine derivatives as glyt1 inhibitors |
| WO2008038251A2 (en) * | 2006-09-29 | 2008-04-03 | Actelion Pharmaceuticals Ltd | 3-aza-bicyclo[3.1.0]hexane derivatives |
| US20080319043A1 (en) * | 2005-05-03 | 2008-12-25 | Mohammad Salman | 3,6-Disubstituted Azabicyclo (3.1.0) Hexane Derivatives as Muscarinic Receptor Antagonists |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5981168A (en) * | 1998-05-15 | 1999-11-09 | The University Of British Columbia | Method and composition for modulating amyloidosis |
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2009
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- 2009-12-29 WO PCT/US2009/069716 patent/WO2010078348A1/en not_active Ceased
- 2009-12-29 US US12/648,972 patent/US8497289B2/en not_active Expired - Fee Related
- 2009-12-29 BR BRPI0923878-6A patent/BRPI0923878A2/pt not_active IP Right Cessation
- 2009-12-29 MX MX2011006845A patent/MX2011006845A/es not_active Application Discontinuation
- 2009-12-29 CA CA2747602A patent/CA2747602A1/en not_active Abandoned
- 2009-12-29 EP EP09837121A patent/EP2381941A4/en not_active Withdrawn
- 2009-12-29 AU AU2009335120A patent/AU2009335120A1/en not_active Abandoned
- 2009-12-29 KR KR1020117016603A patent/KR20110117087A/ko not_active Withdrawn
- 2009-12-29 CN CN2009801530939A patent/CN102271677A/zh active Pending
- 2009-12-29 RU RU2011124709/04A patent/RU2011124709A/ru not_active Application Discontinuation
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2011
- 2011-06-14 IL IL213541A patent/IL213541A0/en unknown
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005037216A2 (en) * | 2003-10-14 | 2005-04-28 | Pfizer Products Inc. | Bicyclic [3.1.0] derivatives as glycine transporter inhibitors |
| WO2006067529A1 (en) * | 2004-12-21 | 2006-06-29 | Merck Sharp & Dohme Limited | Piperidine and azetidine derivatives as glyt1 inhibitors |
| US20080319043A1 (en) * | 2005-05-03 | 2008-12-25 | Mohammad Salman | 3,6-Disubstituted Azabicyclo (3.1.0) Hexane Derivatives as Muscarinic Receptor Antagonists |
| WO2007060484A1 (en) * | 2005-11-25 | 2007-05-31 | Merck Sharp & Dohme Limited | Azetidine derivatives as glyt1 inhibitors |
| WO2008038251A2 (en) * | 2006-09-29 | 2008-04-03 | Actelion Pharmaceuticals Ltd | 3-aza-bicyclo[3.1.0]hexane derivatives |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017514871A (ja) * | 2014-05-06 | 2017-06-08 | ノースウェスタン ユニバーシティ | Nmdar調節化合物の組合せ |
| JP2020138973A (ja) * | 2014-05-06 | 2020-09-03 | ノースウェスタン ユニバーシティ | Nmdar調節化合物の組合せ |
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0923878A2 (pt) | 2015-07-28 |
| KR20110117087A (ko) | 2011-10-26 |
| WO2010078348A1 (en) | 2010-07-08 |
| IL213541A0 (en) | 2011-07-31 |
| US8497289B2 (en) | 2013-07-30 |
| CA2747602A1 (en) | 2010-07-08 |
| EP2381941A1 (en) | 2011-11-02 |
| US20100256192A1 (en) | 2010-10-07 |
| MX2011006845A (es) | 2011-08-04 |
| EP2381941A4 (en) | 2012-08-01 |
| AU2009335120A1 (en) | 2011-07-07 |
| RU2011124709A (ru) | 2013-02-10 |
| CN102271677A (zh) | 2011-12-07 |
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