JP2012513193A5 - - Google Patents

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Publication number
JP2012513193A5
JP2012513193A5 JP2011541487A JP2011541487A JP2012513193A5 JP 2012513193 A5 JP2012513193 A5 JP 2012513193A5 JP 2011541487 A JP2011541487 A JP 2011541487A JP 2011541487 A JP2011541487 A JP 2011541487A JP 2012513193 A5 JP2012513193 A5 JP 2012513193A5
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JP
Japan
Prior art keywords
antibody
seq
tfpi
amino acids
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2011541487A
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English (en)
Japanese (ja)
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JP5791512B2 (ja
JP2012513193A (ja
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Priority claimed from PCT/EP2009/067566 external-priority patent/WO2010072687A1/en
Publication of JP2012513193A publication Critical patent/JP2012513193A/ja
Publication of JP2012513193A5 publication Critical patent/JP2012513193A5/ja
Application granted granted Critical
Publication of JP5791512B2 publication Critical patent/JP5791512B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2011541487A 2008-12-22 2009-12-18 組織因子経路阻害因子（ｔｆｐｉ）に対する抗体 Expired - Fee Related JP5791512B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08172522.8 2008-12-22
EP08172522 2008-12-22
PCT/EP2009/067566 WO2010072687A1 (en) 2008-12-22 2009-12-18 Antibodies against tissue factor pathway inhibitor (tfpi)

Publications (3)

Publication Number Publication Date
JP2012513193A JP2012513193A (ja) 2012-06-14
JP2012513193A5 true JP2012513193A5 (https=) 2012-12-13
JP5791512B2 JP5791512B2 (ja) 2015-10-07

Family

ID=42104649

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011541487A Expired - Fee Related JP5791512B2 (ja) 2008-12-22 2009-12-18 組織因子経路阻害因子（ｔｆｐｉ）に対する抗体

Country Status (6)

Country Link
US (2) US8618263B2 (https=)
EP (1) EP2379599B1 (https=)
JP (1) JP5791512B2 (https=)
CN (1) CN102300876A (https=)
TW (1) TW201026329A (https=)
WO (1) WO2010072687A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010072691A1 (en) * 2008-12-22 2010-07-01 Novo Nordisk A/S Antibodies against tissue factor pathway inhibitor
PT3345615T (pt) 2010-03-01 2020-01-17 Bayer Healthcare Llc Anticorpos monoclonais otimizados contra inibidor da via do fator tecidual (tfpi)
US9228022B2 (en) 2010-06-30 2016-01-05 Novo Nordisk A/S Antibodies that are capable of specifically binding tissue factor pathway inhibitor
JP2013533871A (ja) * 2010-06-30 2013-08-29 ノヴォ ノルディスク アー／エス 組織因子経路インヒビターに特異的に結合することが可能な抗体
US9896513B2 (en) 2013-03-15 2018-02-20 Novo Nordisk A/S Antibodies capable of specifically binding two epitopes on tissue factor pathway inhibitor
US10231993B2 (en) 2013-06-27 2019-03-19 University Of Washington Through Its Center For Commercialization Biocompatible polymeric system for targeted treatment of thrombotic and hemostatic disorders
EP3022228B1 (en) 2013-07-19 2019-02-27 Novo Nordisk A/S Antibodies recognizing the n-terminal part of tissue factor pathway inhibitor capable of eliciting pro-coagulant activity
JP6783754B2 (ja) * 2014-09-17 2020-11-11 ノヴォ ノルディスク アー／エス 組織因子経路インヒビター（１〜１６１）上の２つのエピトープに結合する能力がある抗体
MY178445A (en) * 2015-02-25 2020-10-13 Mogam Inst Biomedical Res Novel antibody binding to tfpi and composition comprising the same
KR102438650B1 (ko) 2015-08-19 2022-08-31 화이자 인코포레이티드 조직 인자 경로 억제제 항체 및 그의 용도
CA3115607A1 (en) 2018-10-11 2020-04-16 Pfizer Inc. Dosage regimen for tfpi antagonists
CN112442127A (zh) * 2019-08-29 2021-03-05 苏州康宁杰瑞生物科技有限公司 针对tfpi的单克隆抗体
WO2025124481A1 (zh) * 2023-12-13 2025-06-19 苏州康宁杰瑞生物科技有限公司 Tfpi抗体用于治疗血友病

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0539975A1 (en) * 1991-10-31 1993-05-05 Teijin Limited Method for immunological assay of free lipoprotein-associated coagulation inhibitor (LACI) and kit therefor
JPH0875736A (ja) * 1994-09-06 1996-03-22 Chemo Sero Therapeut Res Inst ヒト組織因子凝固系インヒビターの定量法

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