JP2012509886A5 - - Google Patents
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- Publication number
- JP2012509886A5 JP2012509886A5 JP2011537606A JP2011537606A JP2012509886A5 JP 2012509886 A5 JP2012509886 A5 JP 2012509886A5 JP 2011537606 A JP2011537606 A JP 2011537606A JP 2011537606 A JP2011537606 A JP 2011537606A JP 2012509886 A5 JP2012509886 A5 JP 2012509886A5
- Authority
- JP
- Japan
- Prior art keywords
- tcl1
- activator protein
- promotes
- pharmaceutical composition
- activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11678608P | 2008-11-21 | 2008-11-21 | |
| US61/116,786 | 2008-11-21 | ||
| PCT/US2009/065072 WO2010059779A1 (en) | 2008-11-21 | 2009-11-19 | Tcl1 AS A TRANSCRIPTIONAL REGULATOR |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012509886A JP2012509886A (ja) | 2012-04-26 |
| JP2012509886A5 true JP2012509886A5 (https=) | 2012-06-07 |
Family
ID=42198493
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011537606A Pending JP2012509886A (ja) | 2008-11-21 | 2009-11-19 | 転写制御因子としてのＴｃｌ１ |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20110311555A1 (https=) |
| EP (1) | EP2352524A1 (https=) |
| JP (1) | JP2012509886A (https=) |
| CN (1) | CN102271706A (https=) |
| AU (1) | AU2009316584A1 (https=) |
| CA (1) | CA2744326A1 (https=) |
| WO (1) | WO2010059779A1 (https=) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5489459B2 (ja) | 2005-08-01 | 2014-05-14 | ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイション | 乳癌の診断、予後及び治療のためのマイクロｒｎａに基づいた方法及び組成物 |
| CA2845251A1 (en) | 2005-09-12 | 2007-03-22 | The Ohio State University Research Foundation | Compositions for the therapy of bcl2-associated cancers and methods of preparation thereof |
| JP5490413B2 (ja) | 2006-01-05 | 2014-05-14 | ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイション | 膵内分泌腫瘍及び膵腺房腫瘍におけるマイクロｒｎａ発現異常 |
| CN102943108B (zh) | 2006-01-05 | 2014-05-21 | 俄亥俄州立大学研究基金会 | 用于肺癌的诊断、预后和治疗的基于微小rna的方法和组合物 |
| EP2487258B1 (en) | 2006-01-05 | 2014-10-01 | The Ohio State University Research Foundation | MicroRNA-based methods for the diagnosis of colon, pancreas and stomach cancer |
| ES2446362T3 (es) | 2006-03-20 | 2014-03-07 | The Ohio State University Research Foundation | Huellas de microARN durante megacariocipoyesis humana |
| CA2657030A1 (en) | 2006-07-13 | 2008-01-17 | The Ohio State University Research Foundation, An Instrumentality Of The State Of Ohio | Micro-rna-based methods and compositions for the diagnosis and treatment of colon cancer-related diseases |
| CN101535505A (zh) | 2006-09-19 | 2009-09-16 | 俄亥俄州立大学研究基金会 | 慢性淋巴细胞性白血病(CLL)中受miR-29和miR-181调控的TCL1的表达 |
| EP2087135B8 (en) | 2006-11-01 | 2013-07-24 | The Ohio State University Research Foundation | Microrna expression signature for predicting survival and metastases in hepatocellular carcinoma |
| CN105256004A (zh) | 2007-01-31 | 2016-01-20 | 俄亥俄州立大学研究基金会 | 用于急性髓细胞白血病(aml)的诊断、预后和治疗的基于微rna的方法和组合物 |
| ES2527648T3 (es) | 2007-06-08 | 2015-01-28 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Métodos para determinar el subtipo de carcinoma hepatocelular |
| EP2719773A3 (en) | 2007-06-15 | 2014-07-30 | The Ohio State University Research Foundation | miRNA as marker for acute lamphomic leucemia |
| ES2496172T3 (es) | 2007-07-31 | 2014-09-18 | The Ohio State University Research Foundation | Métodos para invertir la metilación por selección dirigida de DNMT3A y DNMT3B |
| JP2010535473A (ja) | 2007-08-03 | 2010-11-25 | ズィ、オハイオウ、ステイト、ユーニヴァーサティ、リサーチ、ファウンデイシャン | ｎｃＲＮＡをコードする超保存領域 |
| CA2696887C (en) | 2007-08-22 | 2016-06-28 | The Ohio State University Research Foundation | Methods and compositions for inducing deregulation of epha7 and erk phosphorylation in human acute leukemias |
| CN102137927B (zh) | 2007-10-26 | 2014-03-12 | 俄亥俄州立大学研究基金会 | 鉴定脆性组氨酸三联体(Fhit)相互作用的方法及其用途 |
| ES2433940T3 (es) | 2008-06-11 | 2013-12-13 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Uso de la familia miR-26 como marcador predictivo del carcinoma hepatocelular y sensibilidad a la terapia |
| US8916533B2 (en) | 2009-11-23 | 2014-12-23 | The Ohio State University | Materials and methods useful for affecting tumor cell growth, migration and invasion |
| JP5931897B2 (ja) | 2010-11-12 | 2016-06-08 | ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデイションＴｈｅ Ｏｈｉｏ Ｓｔａｔｅ Ｕｎｉｖｅｒｓｉｔｙ Ｒｅｓｅａｒｃｈ Ｆｏｕｎｄａｔｉｏｎ | マイクロｒｎａ−２１、ミスマッチ修復および結腸直腸癌に関連する物質および方法 |
| CA2817982C (en) | 2010-11-15 | 2020-06-30 | The Regents Of The University Of Michigan | Controlled release mucoadhesive systems |
| WO2012122239A1 (en) | 2011-03-07 | 2012-09-13 | The Ohio State University | MUTATOR ACTIVITY INDUCED BY MICRORNA-155 (miR-155) LINKS INFLAMMATION AND CANCER |
| AU2012323924A1 (en) | 2011-10-14 | 2014-05-29 | The Ohio State University | Methods and materials related to ovarian cancer |
| CA2859430A1 (en) | 2011-12-13 | 2013-06-20 | Ohio State Innovation Foundation | Methods and compositions related to mir-21 and mir-29a, exosome inhibition, and cancer metastasis |
| US8859202B2 (en) | 2012-01-20 | 2014-10-14 | The Ohio State University | Breast cancer biomarker signatures for invasiveness and prognosis |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5985598A (en) * | 1994-10-27 | 1999-11-16 | Thomas Jefferson University | TCL-1 gene and protein and related methods and compositions |
| US20010026796A1 (en) * | 2000-03-14 | 2001-10-04 | Croce Carlo M. | TCL1 enhances Akt kinase activity and mediates its nuclear translocation |
| GB0128898D0 (en) * | 2001-12-03 | 2002-01-23 | Biotech Res Ventures Pte Ltd | Materials and methods relating to the stabilization and activation of a tumour suppressor protein |
| AU2003224672B2 (en) * | 2002-03-08 | 2010-02-04 | Eisai R&D Management Co., Ltd. | Macrocyclic compounds useful as pharmaceuticals |
-
2009
- 2009-11-19 US US13/129,881 patent/US20110311555A1/en not_active Abandoned
- 2009-11-19 WO PCT/US2009/065072 patent/WO2010059779A1/en not_active Ceased
- 2009-11-19 CA CA2744326A patent/CA2744326A1/en not_active Abandoned
- 2009-11-19 JP JP2011537606A patent/JP2012509886A/ja active Pending
- 2009-11-19 CN CN2009801530248A patent/CN102271706A/zh active Pending
- 2009-11-19 AU AU2009316584A patent/AU2009316584A1/en not_active Abandoned
- 2009-11-19 EP EP09828195A patent/EP2352524A1/en not_active Withdrawn
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