JP2012507268A5 - - Google Patents

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Publication number
JP2012507268A5
JP2012507268A5 JP2011533565A JP2011533565A JP2012507268A5 JP 2012507268 A5 JP2012507268 A5 JP 2012507268A5 JP 2011533565 A JP2011533565 A JP 2011533565A JP 2011533565 A JP2011533565 A JP 2011533565A JP 2012507268 A5 JP2012507268 A5 JP 2012507268A5
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JP
Japan
Prior art keywords
meteef1a
metap2
concentration
activity
compound
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JP2011533565A
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English (en)
Japanese (ja)
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JP2012507268A (ja
JP5347028B2 (ja
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Priority claimed from PCT/EP2009/007102 external-priority patent/WO2010051882A1/en
Publication of JP2012507268A publication Critical patent/JP2012507268A/ja
Publication of JP2012507268A5 publication Critical patent/JP2012507268A5/ja
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Publication of JP5347028B2 publication Critical patent/JP5347028B2/ja
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JP2011533565A 2008-11-06 2009-10-05 バイオマーカーとしてのEEF1Aの使用およびMetAP2阻害剤をスクリーニングするための方法 Active JP5347028B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08019432.7 2008-11-06
EP08019432 2008-11-06
PCT/EP2009/007102 WO2010051882A1 (en) 2008-11-06 2009-10-05 Use of eef1a as biomarker and a method of screening metap2 inhibitors

Publications (3)

Publication Number Publication Date
JP2012507268A JP2012507268A (ja) 2012-03-29
JP2012507268A5 true JP2012507268A5 (enExample) 2012-11-22
JP5347028B2 JP5347028B2 (ja) 2013-11-20

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ID=41409225

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011533565A Active JP5347028B2 (ja) 2008-11-06 2009-10-05 バイオマーカーとしてのEEF1Aの使用およびMetAP2阻害剤をスクリーニングするための方法

Country Status (8)

Country Link
US (1) US9151743B2 (enExample)
EP (1) EP2344665B1 (enExample)
JP (1) JP5347028B2 (enExample)
AU (1) AU2009313167C1 (enExample)
CA (1) CA2742737C (enExample)
ES (1) ES2402564T3 (enExample)
IL (1) IL212664A0 (enExample)
WO (1) WO2010051882A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015069489A1 (en) 2013-11-06 2015-05-14 Merck Patent Gmbh Predictive biomarker for hypoxia-activated prodrug therapy
KR101712982B1 (ko) * 2015-07-31 2017-03-07 고려대학교 산학협력단 비알콜성지방간 조절인자 14-3-3 단백질
US20200030278A1 (en) * 2017-02-10 2020-01-30 Zafgen, Inc. Pharmaceutical compositions of metap-2 inhibitors
CN108611352B (zh) * 2018-04-20 2020-08-07 华南农业大学 一种拟禾本科根结线虫翻译延长因子Mg-eEF1A及其防治植物病害的应用
CN115461054A (zh) * 2020-02-06 2022-12-09 加利福尼亚大学董事会 延伸因子1-α抑制剂及其用途
CN116395718B (zh) * 2023-04-12 2024-12-17 中国科学院长春应用化学研究所 一种弱碱性钠盐纳米药物、其制备方法及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998056372A1 (en) * 1997-06-09 1998-12-17 Massachusetts Institute Of Technology TYPE 2 METHIONINE AMINOPEPTIDASE (MetAP2) INHIBITORS AND USES THEROF
WO2002039990A2 (en) * 2000-11-14 2002-05-23 Novartis Ag Method for screening anti-proliferative compounds and inhibiting tumor growth
US20020182701A1 (en) * 2001-08-30 2002-12-05 Saint Louis University Dominant negative variants of methionine aminopeptidase 2 (MetAP2) and clinical uses thereof
US20030232383A1 (en) 2001-11-02 2003-12-18 Sylvia Daunert Novel reagentless sensing system for measuring carbohydrates based on the galactose/glucose binding protein

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