|
US6174868B1
(en)
*
|
1992-09-10 |
2001-01-16 |
Isis Pharmaceuticals, Inc. |
Compositions and methods for treatment of hepatitis C virus-associated diseases
|
|
WO1995030746A1
(en)
*
|
1994-05-10 |
1995-11-16 |
The General Hospital Corporation |
Antisense inhibition of hepatitis c virus
|
|
DE19956568A1
(de)
*
|
1999-01-30 |
2000-08-17 |
Roland Kreutzer |
Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens
|
|
FR2790757B1
(fr)
*
|
1999-03-09 |
2003-08-01 |
Bioalliance Pharma |
Oligonucleotides contenant une sequence antisens stabilises par une structure secondaire et compositions pharmaceutiques les contenant.
|
|
US20070026394A1
(en)
*
|
2000-02-11 |
2007-02-01 |
Lawrence Blatt |
Modulation of gene expression associated with inflammation proliferation and neurite outgrowth using nucleic acid based technologies
|
|
US8202979B2
(en)
*
|
2002-02-20 |
2012-06-19 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid
|
|
EP1873259B1
(en)
*
|
2000-12-01 |
2012-01-25 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
RNA interference mediated by 21 and 22nt RNAs
|
|
US20040209831A1
(en)
*
|
2002-02-20 |
2004-10-21 |
Mcswiggen James |
RNA interference mediated inhibition of hepatitis C virus (HCV) gene expression using short interfering nucleic acid (siNA)
|
|
US10590418B2
(en)
|
2001-07-23 |
2020-03-17 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and compositions for RNAi mediated inhibition of gene expression in mammals
|
|
US20040138163A1
(en)
*
|
2002-05-29 |
2004-07-15 |
Mcswiggen James |
RNA interference mediated inhibition of vascular edothelial growth factor and vascular edothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
|
|
US7294504B1
(en)
*
|
2001-12-27 |
2007-11-13 |
Allele Biotechnology & Pharmaceuticals, Inc. |
Methods and compositions for DNA mediated gene silencing
|
|
ATE519774T1
(de)
|
2002-02-20 |
2011-08-15 |
Sirna Therapeutics Inc |
Durch eine störung der rna vermittelte inhibierung der genexpression des hepatitis c virus (hcv) mit kurzer, störender nukleinsäure (short interfering nucleic acid, sina)
|
|
US20040053876A1
(en)
*
|
2002-03-26 |
2004-03-18 |
The Regents Of The University Of Michigan |
siRNAs and uses therof
|
|
US20040058886A1
(en)
*
|
2002-08-08 |
2004-03-25 |
Dharmacon, Inc. |
Short interfering RNAs having a hairpin structure containing a non-nucleotide loop
|
|
JP4948163B2
(ja)
*
|
2003-05-23 |
2012-06-06 |
サーナ・セラピューティクス・インコーポレイテッド |
化学修飾した低分子干渉核酸(siNA)を使用する遺伝子発現のRNA干渉仲介抑制
|
|
US7750144B2
(en)
*
|
2003-06-02 |
2010-07-06 |
University Of Massachusetts |
Methods and compositions for enhancing the efficacy and specificity of RNA silencing
|
|
AU2004257200A1
(en)
*
|
2003-07-07 |
2005-01-27 |
Cellay Llc |
Hairpin-labeled probes and methods of use
|
|
WO2005007877A2
(en)
*
|
2003-07-18 |
2005-01-27 |
University Of Massachusetts |
Regulatable promoters for synthesis of small hairpin rna
|
|
WO2005028650A2
(en)
*
|
2003-09-16 |
2005-03-31 |
Sirna Therapeutics, Inc. |
RNA INTERFERENCE MEDIATED INHIBITION OF HEPATITIS C VIRUS (HCV) EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
|
WO2005028646A1
(ja)
|
2003-09-22 |
2005-03-31 |
Riken |
効率的なdna逆位反復構造の調製方法
|
|
US20060134787A1
(en)
*
|
2004-12-22 |
2006-06-22 |
University Of Massachusetts |
Methods and compositions for enhancing the efficacy and specificity of single and double blunt-ended siRNA
|
|
US20050164210A1
(en)
*
|
2004-01-23 |
2005-07-28 |
Vivek Mittal |
Regulated polymerase III expression systems and related methods
|
|
WO2005079533A2
(en)
|
2004-02-17 |
2005-09-01 |
University Of Massachusetts |
Methods and compositions for mediating gene silencing
|
|
CA2579790A1
(en)
*
|
2004-07-30 |
2006-02-09 |
Mount Sinai School Of Medicine Of New York University |
Npc1l1 and npc1l1 inhibitors and methods of use thereof
|
|
EP1793835A4
(en)
*
|
2004-09-10 |
2010-12-01 |
Somagenics Inc |
SMALL INTERFERING RNA EFFECTIVELY INHIBITING VIRAL GENE EXPRESSION AND METHODS OF USE THEREOF
|
|
US20060142228A1
(en)
*
|
2004-12-23 |
2006-06-29 |
Ambion, Inc. |
Methods and compositions concerning siRNA's as mediators of RNA interference
|
|
WO2006074108A2
(en)
*
|
2004-12-30 |
2006-07-13 |
Hauser Todd M |
Compositions and methods for modulating gene expression using self-protected oligonucleotides
|
|
US20060223777A1
(en)
*
|
2005-03-29 |
2006-10-05 |
Dharmacon, Inc. |
Highly functional short hairpin RNA
|
|
US20070048759A1
(en)
*
|
2005-06-10 |
2007-03-01 |
Dan Luo |
Detection of target molecules with labeled nucleic acid detection molecules
|
|
CN102827841A
(zh)
*
|
2005-09-12 |
2012-12-19 |
索马根尼科斯公司 |
利用小干扰rna抑制病毒基因表达
|
|
WO2007087451A2
(en)
*
|
2006-01-25 |
2007-08-02 |
University Of Massachusetts |
Compositions and methods for enhancing discriminatory rna interference
|
|
EP2002004B1
(en)
*
|
2006-03-23 |
2015-10-14 |
Roche Innovation Center Copenhagen A/S |
Small internally segmented interfering rna
|
|
EP3121281B1
(en)
*
|
2007-08-27 |
2021-03-31 |
1Globe Health Institute LLC |
Compositions of asymmetric interfering rna and uses thereof
|
|
KR100949791B1
(ko)
*
|
2007-12-18 |
2010-03-30 |
이동기 |
오프-타겟 효과를 최소화하고 RNAi 기구를 포화시키지않는 신규한 siRNA 구조 및 그 용도
|
|
CN102245772A
(zh)
|
2008-10-15 |
2011-11-16 |
索马根尼科斯公司 |
抑制基因表达的短发卡rna
|