JP2012503024A5 - - Google Patents
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- Publication number
- JP2012503024A5 JP2012503024A5 JP2011528081A JP2011528081A JP2012503024A5 JP 2012503024 A5 JP2012503024 A5 JP 2012503024A5 JP 2011528081 A JP2011528081 A JP 2011528081A JP 2011528081 A JP2011528081 A JP 2011528081A JP 2012503024 A5 JP2012503024 A5 JP 2012503024A5
- Authority
- JP
- Japan
- Prior art keywords
- peptidomimetic macrocycle
- amino acid
- peptidomimetic
- independently
- macrocycle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9917208P | 2008-09-22 | 2008-09-22 | |
| US61/099,172 | 2008-09-22 | ||
| PCT/US2009/057927 WO2010034028A1 (en) | 2008-09-22 | 2009-09-22 | Peptidomimetic marcrocycles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012503024A JP2012503024A (ja) | 2012-02-02 |
| JP2012503024A5 true JP2012503024A5 (cg-RX-API-DMAC7.html) | 2012-05-24 |
Family
ID=41581947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011528081A Withdrawn JP2012503024A (ja) | 2008-09-22 | 2009-09-22 | ペプチド模倣大環状分子 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20120115783A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2342214A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2012503024A (cg-RX-API-DMAC7.html) |
| CN (1) | CN102197046A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2009294871A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0918833A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2737916A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2010034028A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0720306A2 (pt) | 2006-12-14 | 2014-02-04 | Aileron Therapeutics Inc | Sistemas de macrociclização da bis-sufidrila |
| CA2678941C (en) | 2007-02-23 | 2018-11-27 | Aileron Therapeutics, Inc. | Triazole macrocycle systems |
| KR20160061439A (ko) | 2007-03-28 | 2016-05-31 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | 스티칭된 폴리펩티드 |
| EP2344520B1 (en) * | 2008-09-18 | 2013-11-13 | New York University | Inhibiting interaction between hif-1a and p300/cbp with hydrogen bond surrogate-based helices |
| WO2010034034A1 (en) | 2008-09-22 | 2010-03-25 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
| BRPI0920899A2 (pt) | 2008-11-24 | 2016-04-26 | Aileron Therapeutics Inc | macrociclos peptidomiméticos com propriedades melhoradas |
| BRPI1006139A2 (pt) | 2009-01-14 | 2017-05-30 | Aileron Therapeutics Inc | macrociclos peptidomiméticos |
| US20130072439A1 (en) | 2009-09-22 | 2013-03-21 | Huw M. Nash | Peptidomimetic macrocycles |
| MX355543B (es) | 2010-08-13 | 2018-04-20 | Aileron Therapeutics Inc Star | Macrociclos peptidomiméticos. |
| EP2627662B1 (en) | 2010-10-13 | 2015-09-16 | Bristol-Myers Squibb Company | Methods for preparing macrocycles and macrocycle stabilized peptides |
| RU2639523C2 (ru) | 2011-10-18 | 2017-12-21 | Эйлерон Терапьютикс, Инк. | Пептидомиметические макроциклы и их применение |
| JP6450191B2 (ja) * | 2012-02-15 | 2019-01-09 | エイルロン セラピューティクス，インコーポレイテッド | ペプチドミメティック大環状化合物 |
| HK1205454A1 (en) | 2012-02-15 | 2015-12-18 | Aileron Therapeutics, Inc. | Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles |
| US9604919B2 (en) | 2012-11-01 | 2017-03-28 | Aileron Therapeutics, Inc. | Disubstituted amino acids and methods of preparation and use thereof |
| US20140205681A1 (en) | 2013-01-19 | 2014-07-24 | New York University | HYDROGEN-BOND SURROGATE PEPTIDES AND PEPTIDOMIMETICS FOR p53 REACTIVATION |
| WO2014138429A2 (en) * | 2013-03-06 | 2014-09-12 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and use thereof in regulating hif1alpha |
| WO2016049355A1 (en) | 2014-09-24 | 2016-03-31 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and formulations thereof |
| SG11201702223UA (en) | 2014-09-24 | 2017-04-27 | Aileron Therapeutics Inc | Peptidomimetic macrocycles and uses thereof |
| EP3294318A4 (en) | 2015-03-20 | 2019-04-03 | Aileron Therapeutics, Inc. | PEPTIDOMIMETIC MACROCYCLES AND USES THEREOF |
| US10059741B2 (en) | 2015-07-01 | 2018-08-28 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
| JP2018528217A (ja) | 2015-09-10 | 2018-09-27 | エルロン・セラピューティクス・インコーポレイテッドＡｉｌｅｒｏｎ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． | Ｍｃｌ−１のモジュレーターとしてのペプチド模倣大環状分子 |
| EP4023295A1 (en) | 2020-12-29 | 2022-07-06 | IDP Discovery Pharma, S.L. | Vegf-regulating peptides |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2830063C (en) * | 2003-11-05 | 2017-10-31 | Dana-Farber Cancer Institute, Inc. | Stabilized alpha helical peptides and uses thereof |
| US8143228B2 (en) * | 2004-07-12 | 2012-03-27 | Medical Research Fund Of Tel Aviv Sourasky Medical Center | Agents capable of downregulating an MSF-A dependent HIF-1α and use thereof in cancer treatment |
| JP2010505831A (ja) * | 2006-10-05 | 2010-02-25 | ニューヨーク ブラッド センター， インコーポレイテッド | 安定化した、治療用の小型のヘリックス性抗ウイルスペプチド |
| BRPI0720306A2 (pt) * | 2006-12-14 | 2014-02-04 | Aileron Therapeutics Inc | Sistemas de macrociclização da bis-sufidrila |
| CA2678941C (en) * | 2007-02-23 | 2018-11-27 | Aileron Therapeutics, Inc. | Triazole macrocycle systems |
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2009
- 2009-09-22 BR BRPI0918833A patent/BRPI0918833A2/pt not_active IP Right Cessation
- 2009-09-22 AU AU2009294871A patent/AU2009294871A1/en not_active Abandoned
- 2009-09-22 CA CA2737916A patent/CA2737916A1/en not_active Abandoned
- 2009-09-22 US US13/120,376 patent/US20120115783A1/en not_active Abandoned
- 2009-09-22 CN CN2009801422968A patent/CN102197046A/zh active Pending
- 2009-09-22 EP EP09743980A patent/EP2342214A1/en not_active Withdrawn
- 2009-09-22 WO PCT/US2009/057927 patent/WO2010034028A1/en not_active Ceased
- 2009-09-22 JP JP2011528081A patent/JP2012503024A/ja not_active Withdrawn