JP2012503024A5 - - Google Patents

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Publication number
JP2012503024A5
JP2012503024A5 JP2011528081A JP2011528081A JP2012503024A5 JP 2012503024 A5 JP2012503024 A5 JP 2012503024A5 JP 2011528081 A JP2011528081 A JP 2011528081A JP 2011528081 A JP2011528081 A JP 2011528081A JP 2012503024 A5 JP2012503024 A5 JP 2012503024A5
Authority
JP
Japan
Prior art keywords
peptidomimetic macrocycle
amino acid
peptidomimetic
independently
macrocycle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2011528081A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012503024A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2009/057927 external-priority patent/WO2010034028A1/en
Publication of JP2012503024A publication Critical patent/JP2012503024A/ja
Publication of JP2012503024A5 publication Critical patent/JP2012503024A5/ja
Withdrawn legal-status Critical Current

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JP2011528081A 2008-09-22 2009-09-22 ペプチド模倣大環状分子 Withdrawn JP2012503024A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9917208P 2008-09-22 2008-09-22
US61/099,172 2008-09-22
PCT/US2009/057927 WO2010034028A1 (en) 2008-09-22 2009-09-22 Peptidomimetic marcrocycles

Publications (2)

Publication Number Publication Date
JP2012503024A JP2012503024A (ja) 2012-02-02
JP2012503024A5 true JP2012503024A5 (OSRAM) 2012-05-24

Family

ID=41581947

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011528081A Withdrawn JP2012503024A (ja) 2008-09-22 2009-09-22 ペプチド模倣大環状分子

Country Status (8)

Country Link
US (1) US20120115783A1 (OSRAM)
EP (1) EP2342214A1 (OSRAM)
JP (1) JP2012503024A (OSRAM)
CN (1) CN102197046A (OSRAM)
AU (1) AU2009294871A1 (OSRAM)
BR (1) BRPI0918833A2 (OSRAM)
CA (1) CA2737916A1 (OSRAM)
WO (1) WO2010034028A1 (OSRAM)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105061577A (zh) 2006-12-14 2015-11-18 爱勒让治疗公司 双巯基大环化系统
CN109627287A (zh) 2007-02-23 2019-04-16 爱勒让治疗公司 三唑大环系统
JP5631201B2 (ja) 2007-03-28 2014-11-26 プレジデント アンド フェローズ オブ ハーバード カレッジ ステッチングされたポリペプチド
ES2446249T3 (es) 2008-09-18 2014-03-06 New York University Inhibición de la interación entre hif-1a y p300/cbp con hélices basadas en sustitutos de los enlaces de hidrógeno
BRPI0918948A2 (pt) 2008-09-22 2015-12-15 Aileron Therapeutics Inc macrociclos peptidomiméticos
JP2012509902A (ja) 2008-11-24 2012-04-26 エルロン・セラピューティクス・インコーポレイテッド 改善された特性を有するペプチド模倣大環状分子
EP2376100B1 (en) 2009-01-14 2017-10-25 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
WO2011038049A1 (en) 2009-09-22 2011-03-31 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
MX355543B (es) 2010-08-13 2018-04-20 Aileron Therapeutics Inc Star Macrociclos peptidomiméticos.
EP2627662B1 (en) 2010-10-13 2015-09-16 Bristol-Myers Squibb Company Methods for preparing macrocycles and macrocycle stabilized peptides
TWI643868B (zh) 2011-10-18 2018-12-11 艾利倫治療公司 擬肽巨環化合物
EP2819688A4 (en) 2012-02-15 2015-10-28 Aileron Therapeutics Inc PEPTIDOMIMETIC MACROCYCLES CROSS-LINKED WITH TRIAZOLE AND THIOETHER
SG11201404648PA (en) 2012-02-15 2014-09-26 Aileron Therapeutics Inc Peptidomimetic macrocycles
KR20150082307A (ko) 2012-11-01 2015-07-15 에일러론 테라퓨틱스 인코포레이티드 이치환 아미노산 및 이의 제조 및 사용 방법
EP2964245A4 (en) 2013-01-19 2016-09-21 Univ New York HYDROGENIC SURROGATE PEPTIDES AND PEPTIDOMIMETICS FOR THE REACTIVATION OF P53
WO2014138429A2 (en) * 2013-03-06 2014-09-12 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and use thereof in regulating hif1alpha
SG11201702223UA (en) 2014-09-24 2017-04-27 Aileron Therapeutics Inc Peptidomimetic macrocycles and uses thereof
EP3197477A4 (en) 2014-09-24 2018-07-04 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and formulations thereof
KR20170129879A (ko) 2015-03-20 2017-11-27 에일러론 테라퓨틱스 인코포레이티드 펩티드모방 거대고리 및 이의 용도
US10059741B2 (en) 2015-07-01 2018-08-28 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
JP2018528217A (ja) 2015-09-10 2018-09-27 エルロン・セラピューティクス・インコーポレイテッドAileron Therapeutics,Inc. Mcl−1のモジュレーターとしてのペプチド模倣大環状分子
EP4023295A1 (en) * 2020-12-29 2022-07-06 IDP Discovery Pharma, S.L. Vegf-regulating peptides

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI1680443T1 (sl) * 2003-11-05 2014-01-31 Dana-Farber Cancer Institute, Inc. Stabilizirani peptidi z alfa vijačnico in uporabe le-teh
US8143228B2 (en) * 2004-07-12 2012-03-27 Medical Research Fund Of Tel Aviv Sourasky Medical Center Agents capable of downregulating an MSF-A dependent HIF-1α and use thereof in cancer treatment
WO2008045238A2 (en) * 2006-10-05 2008-04-17 New York Blood Center, Inc. Stabilized therapeutic small helical antiviral peptides
CN105061577A (zh) * 2006-12-14 2015-11-18 爱勒让治疗公司 双巯基大环化系统
CN109627287A (zh) * 2007-02-23 2019-04-16 爱勒让治疗公司 三唑大环系统

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