JP2012180344A5 - - Google Patents

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Publication number
JP2012180344A5
JP2012180344A5 JP2012023811A JP2012023811A JP2012180344A5 JP 2012180344 A5 JP2012180344 A5 JP 2012180344A5 JP 2012023811 A JP2012023811 A JP 2012023811A JP 2012023811 A JP2012023811 A JP 2012023811A JP 2012180344 A5 JP2012180344 A5 JP 2012180344A5
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JP
Japan
Prior art keywords
alkyl
membered
haloalkyl
membered heterocyclyl
aryl
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JP2012023811A
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English (en)
Japanese (ja)
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JP2012180344A (ja
JP5620417B2 (ja
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Priority to JP2012023811A priority Critical patent/JP5620417B2/ja
Priority claimed from JP2012023811A external-priority patent/JP5620417B2/ja
Publication of JP2012180344A publication Critical patent/JP2012180344A/ja
Publication of JP2012180344A5 publication Critical patent/JP2012180344A5/ja
Application granted granted Critical
Publication of JP5620417B2 publication Critical patent/JP5620417B2/ja
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JP2012023811A 2011-02-07 2012-02-07 アミノピラゾール誘導体を含む医薬 Active JP5620417B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2012023811A JP5620417B2 (ja) 2011-02-07 2012-02-07 アミノピラゾール誘導体を含む医薬

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2011024078 2011-02-07
JP2011024078 2011-02-07
JP2012023811A JP5620417B2 (ja) 2011-02-07 2012-02-07 アミノピラゾール誘導体を含む医薬

Publications (3)

Publication Number Publication Date
JP2012180344A JP2012180344A (ja) 2012-09-20
JP2012180344A5 true JP2012180344A5 (pt) 2014-10-02
JP5620417B2 JP5620417B2 (ja) 2014-11-05

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ID=47011846

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012023811A Active JP5620417B2 (ja) 2011-02-07 2012-02-07 アミノピラゾール誘導体を含む医薬

Country Status (1)

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JP (1) JP5620417B2 (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA031631B1 (ru) * 2012-09-27 2019-01-31 Чугаи Сеияку Кабушики Каиша Способ лечения или предупреждения злокачественного новообразования, способ отбора пациента, способ тестирования предрасположенности к злокачественному новообразованию у субъекта, гибридный полипептид и его применения
CN103224479B (zh) * 2013-04-26 2014-10-15 温州大学 一种2-芳基苯并呋喃类化合物的合成方法
US9814776B2 (en) * 2013-07-31 2017-11-14 Chugai Seiyaku Kabushiki Kaisha Pharmaceutical preparation comprising aminopyrazole derivative
AP2016009156A0 (en) * 2013-10-25 2016-04-30 Novartis Ag Ring-fused bicyclic pyridyl derivatives as fgfr4 inhibitors
US9802920B2 (en) 2013-12-13 2017-10-31 Hoffman-La Roche Inc. Inhibitors of bruton's tyrosine kinase
CN105793252B (zh) 2013-12-13 2018-01-30 豪夫迈·罗氏有限公司 布鲁顿氏酪氨酸激酶抑制剂
TW201609093A (zh) * 2013-12-27 2016-03-16 Chugai Pharmaceutical Co Ltd Ｆｇｆｒ門控蛋白變異基因及以其爲標的之醫藥
SG10201808565QA (en) * 2014-03-31 2018-11-29 Debiopharm Int Sa Fgfr fusions
WO2016054483A1 (en) 2014-10-03 2016-04-07 Novartis Ag Use of ring-fused bicyclic pyridyl derivatives as fgfr4 inhibitors
US9802917B2 (en) * 2015-03-25 2017-10-31 Novartis Ag Particles of N-(5-cyano-4-((2-methoxyethyl)amino)pyridin-2-yl)-7-formyl-6-((4-methyl-2-oxopiperazin-1-yl)methyl)-3,4-dihydro-1,8-naphthyridine-1(2H)-carboxamide
US10479780B2 (en) 2015-06-17 2019-11-19 Chugai Seiyaku Kabushiki Kaisha Aminopyrazole derivatives
CN107406431B (zh) * 2015-08-20 2020-06-26 上海昂睿医药技术有限公司 吲哚类衍生物及其制备方法和其在医药上的用途
CN110950848B (zh) * 2018-09-27 2024-03-26 徐诺药业 新型氨基吡唑类衍生物的合成与应用
CN112358435B (zh) * 2019-10-12 2023-01-10 中国医学科学院医药生物技术研究所 取代芳并杂环类化合物、制备方法和抑制ulk1及抗肿瘤用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE292118T1 (de) * 1998-05-05 2005-04-15 Hoffmann La Roche Pyrazolderivative als p-38 map kinase inhibitoren
US6316466B1 (en) * 1998-05-05 2001-11-13 Syntex (U.S.A.) Llc Pyrazole derivatives P-38 MAP kinase inhibitors
CN1832928B (zh) * 2003-06-26 2012-07-04 诺瓦提斯公司 以5元杂环为基础的p38激酶抑制剂
ES2383273T3 (es) * 2008-07-23 2012-06-19 F. Hoffmann-La Roche Ag Compuestos heterocíclicos antivíricos

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