JP2012100636A5 - - Google Patents
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- Publication number
- JP2012100636A5 JP2012100636A5 JP2010254565A JP2010254565A JP2012100636A5 JP 2012100636 A5 JP2012100636 A5 JP 2012100636A5 JP 2010254565 A JP2010254565 A JP 2010254565A JP 2010254565 A JP2010254565 A JP 2010254565A JP 2012100636 A5 JP2012100636 A5 JP 2012100636A5
- Authority
- JP
- Japan
- Prior art keywords
- aptamer
- aptamer rna
- base sequence
- rna
- rna according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 108091023037 Aptamer Proteins 0.000 claims 14
- 239000004480 active ingredient Substances 0.000 claims 5
- 108090000623 proteins and genes Proteins 0.000 claims 5
- 102000004169 proteins and genes Human genes 0.000 claims 5
- 241000712461 unidentified influenza virus Species 0.000 claims 5
- 239000002773 nucleotide Substances 0.000 claims 4
- 125000003729 nucleotide group Chemical group 0.000 claims 4
- 108020004414 DNA Proteins 0.000 claims 3
- 206010022000 influenza Diseases 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 102000053602 DNA Human genes 0.000 claims 2
- 239000002202 Polyethylene glycol Substances 0.000 claims 2
- IQFYYKKMVGJFEH-XLPZGREQSA-N Thymidine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](O)C1 IQFYYKKMVGJFEH-XLPZGREQSA-N 0.000 claims 2
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 claims 2
- 229920001223 polyethylene glycol Polymers 0.000 claims 2
- 108020004394 Complementary RNA Proteins 0.000 claims 1
- HMFHBZSHGGEWLO-SOOFDHNKSA-N D-ribofuranose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H]1O HMFHBZSHGGEWLO-SOOFDHNKSA-N 0.000 claims 1
- 238000009007 Diagnostic Kit Methods 0.000 claims 1
- PYMYPHUHKUWMLA-LMVFSUKVSA-N Ribose Natural products OC[C@@H](O)[C@@H](O)[C@@H](O)C=O PYMYPHUHKUWMLA-LMVFSUKVSA-N 0.000 claims 1
- 108020004682 Single-Stranded DNA Proteins 0.000 claims 1
- HMFHBZSHGGEWLO-UHFFFAOYSA-N alpha-D-Furanose-Ribose Natural products OCC1OC(O)C(O)C1O HMFHBZSHGGEWLO-UHFFFAOYSA-N 0.000 claims 1
- 238000007385 chemical modification Methods 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 230000000295 complement effect Effects 0.000 claims 1
- 239000003184 complementary RNA Substances 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 229940039227 diagnostic agent Drugs 0.000 claims 1
- 239000000032 diagnostic agent Substances 0.000 claims 1
- 125000001153 fluoro group Chemical group F* 0.000 claims 1
- 229910052739 hydrogen Chemical group 0.000 claims 1
- 239000001257 hydrogen Chemical group 0.000 claims 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 1
- 238000012986 modification Methods 0.000 claims 1
- 230000004048 modification Effects 0.000 claims 1
- 125000000548 ribosyl group Chemical group C1([C@H](O)[C@H](O)[C@H](O1)CO)* 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010254565A JP5717127B2 (ja) | 2010-11-15 | 2010-11-15 | 新型インフルエンザウイルスのヘマグルチニンに結合するアプタマー |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010254565A JP5717127B2 (ja) | 2010-11-15 | 2010-11-15 | 新型インフルエンザウイルスのヘマグルチニンに結合するアプタマー |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012100636A JP2012100636A (ja) | 2012-05-31 |
| JP2012100636A5 true JP2012100636A5 (enExample) | 2013-04-11 |
| JP5717127B2 JP5717127B2 (ja) | 2015-05-13 |
Family
ID=46391869
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010254565A Active JP5717127B2 (ja) | 2010-11-15 | 2010-11-15 | 新型インフルエンザウイルスのヘマグルチニンに結合するアプタマー |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP5717127B2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5974221B2 (ja) * | 2012-06-29 | 2016-08-23 | 国立研究開発法人産業技術総合研究所 | Ｈ７ｎ７亜型インフルエンザウイルスのヘマグルチニンに結合するアプタマー |
| JP6103637B2 (ja) * | 2013-06-04 | 2017-03-29 | 国立研究開発法人産業技術総合研究所 | 高病原性鳥インフルエンザウイルスの検出及びサーベイランス |
| TWI480374B (zh) * | 2013-10-23 | 2015-04-11 | Nat Univ Tsing Hua | 針對ａ型流感ｈ１亞型病毒具有高專一性的適合體及其應用 |
| CA3116767A1 (en) * | 2018-10-26 | 2020-04-30 | North Carolina State University | Compositions and methods related to nucleic acid anticoagulants |
| JP7353622B2 (ja) * | 2019-08-02 | 2023-10-02 | 国立大学法人北陸先端科学技術大学院大学 | アプタマーの製造方法とその応用 |
| US11732267B2 (en) | 2020-10-30 | 2023-08-22 | Arkray, Inc. | Nucleic acid aptamer for influenza virus and detection of influenza virus |
| JP7696809B2 (ja) * | 2020-10-30 | 2025-06-23 | アークレイ株式会社 | インフルエンザウイルスの核酸アプタマー及び検出 |
| CN114854760A (zh) * | 2022-06-27 | 2022-08-05 | 华侨大学 | 小鼠抗体的dna适配体及其应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2517074A1 (en) * | 2003-02-27 | 2004-09-10 | Yeda Research And Development Co., Ltd. | Nucleic acid molecules, polypeptides, antibodies and compositions containing same useful for treating and detecting influenza virus infection |
| JP4441618B2 (ja) * | 2003-10-06 | 2010-03-31 | 独立行政法人産業技術総合研究所 | インフルエンザウイルスの検出方法 |
-
2010
- 2010-11-15 JP JP2010254565A patent/JP5717127B2/ja active Active
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