JP2012032188A - Automatic analysis system - Google Patents

Abstract

PROBLEM TO BE SOLVED: To solve the problem in which: a management range in precision management is determined mostly based on storage of past data, and the management range is frequently not appropriately calculated when stored data is little or just after a lot number is updated, thereby causing the management range to be determined from experiences in the past and somewhat lack objectivity; and countermeasures for investigating factors in a data defect during precision management sample or patient specimen analysis are frequently delayed because there is no objective comparison reference data.SOLUTION: For a precision management material as fundamental data when selling a reagent kit, reproducible data, stability of calibration, reagent linearity, a degree of influences of a coexistent material, correlation between machine types, cross contamination information, and reagent instruction manual (package insert) data are digitized and uploaded to a dedicated server. A client uses an Internet line to search for information while using a dedicated PC of an apparatus accessory.

Description

  The present invention relates to an automatic analysis system for searching various data related to a test reagent mounted on a clinical test automatic analyzer for testing specimens such as blood and urine, and various data affecting the performance of the reagent, In particular, the server body that stores information and the analysis device are connected via an Internet line, and the data can be checked. Calibration data and quality control data that are measured daily, and objective comparison of patient sample measurement results, etc. The present invention relates to an automatic analysis system that makes it possible.

  Currently, the quality control method of automatic analyzers in clinical tests is to control the quality control substance that has been measured by interrupting the quality control substance (control sample) at the final concentration during measurement of patient specimens. The accuracy of the automatic analyzer is judged from the accuracy of the accuracy by examining the deviation from the value, daily fluctuation, and daily fluctuation. There are various causes of inaccuracy, which can be broadly divided into four points: a problem with the apparatus, a problem with the reagent, a problem with the quality control substance, and an operation error including condition setting. When defective data appears, the operator must inspect each part to solve the problem. For the equipment, the last maintenance time such as replacement of parts with a limited life such as cells and lamps and cleaning of the reaction tank, for the reagent, the reagent lot number, opening time, stability, and the change in the calibration factor value due to the reagent lot update , Upper limit of reagent linearity, presence / absence and extent of coexisting substances, combination and degree of items that cause cross contamination, for quality control substances, concentration and evaporation occurrence, reproduction of quality control substances currently used Such as sex data. There are a wide variety of such check points, and when data failure occurs, the operator needs to investigate the existence of problems in each part of the device and the materials and academic literature attached to the reagents. Needed. In the current technology, replacement history information of long-lived parts such as cells and lamps can be confirmed to some extent by using the operation information management function in the device, but there is no data confirmation tool related to reagents and quality control substances. Is the current situation. In particular, the calibration factor and quality control substance reproducibility data may change in the measurement results due to lot updates. However, it is possible to compare and verify the basic data of reagents and quality control substances that users use in real time. In many cases, it is not possible to make a quick pass / fail judgment.

  Patent Documents 1 and 2 describe techniques for solving the above problems by collecting and analyzing measurement data of individual analyzers via public lines such as the Internet and providing analysis results to individual facilities. Has been.

JP 2002-340906 A JP 2009-181369 A

  The accuracy management method of the automatic analyzer is a method in which an operator periodically interrupts a quality control material and measures it, and checks the presence or absence of data abnormality based on how the measured value fluctuates. Previous quality control systems judge whether the measurement results of quality control substances are within the control range, and whether there are data abnormalities due to trends such as whether the fluctuations of quality control substances are systematic fluctuations or accidental fluctuations The main purpose is to investigate the cause. In general, when performing quality control for routine measurement using quality control materials released by reagent manufacturers, etc., the display value and control width are attached to each quality control material marketed by the manufacturer for each vial. However, the range of detailed reproducibility is not specified. Furthermore, the reproducibility data of quality control substances that are generally available on the market are not necessarily those measured by equivalent devices and reagents owned by customers. For this reason, it is difficult for the user to judge the quality of the measured data, and even if there is a data failure, there are few materials for accurate comparison and judgment. The current situation. For this reason, young inspection technicians with little experience have spent a lot of time solving problems, resulting in delays in other inspection tasks. Furthermore, since reagents and quality control substances are produced in units of one lot, there is a possibility that individual differences may occur depending on the date and time of manufacture. Therefore, the user always keeps an eye on the update timing of reagents and quality control substances. Need to get real-time information. In addition, data sheets attached to reagents and quality control substances are often data acquired using an arbitrary device, not data acquired by a customer's own device.

  The information that the user wants to know is the reproducibility result when measuring using the equipment used for analysis in the facility, the reagent of the same lot number, and the quality control substance. In addition, the stability of calibration that controls the data of quality control substances, the reproducibility of quality control substances, linearity, the influence of coexisting substances, correlation data with other devices, presence or absence of contamination, composition table and reaction formula are posted. If the operator can instantly obtain the objective information and the like, the problem can be solved quickly when defective data occurs.

  The object of the present invention is to store new data in the database every time the quality control substance or reagent lot number is updated, and it becomes possible for an unspecified number of users to search and browse data and information suitable for their facilities. To provide an automatic analysis system.

  Currently, clinical laboratory analysis is performed using an external diagnostic reagent (reagent kit) released by a reagent manufacturer in an automatic analyzer for biochemistry. The reagent kit is attached with data indicating the performance of the reagent and data specifying the handling method. The contents of the material represent the performance of the reagent. For example, (1) Analytical parameters of each device (2) Reproducibility of quality control materials (3) Stability of calibration results (4) Reagent linearity (5) Coexisting materials (6) Correlation with other models (7) Contamination information in the reagent probe / reaction cell (8) There is data related to the instruction manual (booklet) attached to the reagent kit. Therefore, this data is digitized and stored in a dedicated server, and a system for searching and browsing necessary information is constructed through an operation PC attached to the customer's analyzer via a dedicated Internet line. The operation PC terminal attached to the analyzer is provided with items, selection branches, and function screens necessary for selecting information to be browsed. When downloading information, the user automatically reads the barcode information attached to the reagent bottle installed in the apparatus, and the corresponding reagent data can be downloaded from the lot number and bottle number information. To do.

  For example, in the content shown in the reproducibility data of the quality control substance in (2) above, the accuracy used for the measurement, in addition to statistical data such as the average value, maximum value, minimum value, range, standard deviation, coefficient of variation of the measurement results It is possible to retrieve the lot number of the controlled substance, the lot number of the standard substance used for calibration, the lot number of the reagent used for measurement, the number of effective days, and the expiration date after opening. In addition, when the lot number of quality control substances or reagents is added or changed, the system also sequentially uploads information to the dedicated server regarding the values measured in the new lot. From this result, an unspecified number of users can browse the measurement result of the quality control substance using the reagent of the lot number currently used in their own facility.

  Regarding the calibration stability of (3) above, it is possible to confirm the calibration results for one week, for example. The main wavelength and sub-wavelength absorbance data of the calibration result, the reagent lot number, the lot number of the standard substance used in the calibration, the concentration setting value, and the calibration result (S1Abs, K value) information are displayed. When downloading data, the barcode information of the reagent being used is automatically read, the server database is searched from the reagent lot number information, and the data when the relevant lot reagent is used is downloaded. .

  Furthermore, regarding the reagent linearity result of (4), it is important to determine whether or not the measurement is correctly performed when measuring an abnormally high patient sample. The analyzer checks whether the change in absorbance within the photometric point range determined by the analysis parameters is completed within the set value. However, the reagent linearity range in the new state becomes narrow due to the deterioration of the reagent components. Sometimes. Changes over time in reagent degradation can be confirmed in combination with calibration stability data. When downloading data, the barcode information of the reagent being used is automatically read, the server database is searched from the lot number information of the reagent, and the linearity data when the corresponding lot reagent is used is automatically obtained. Extract and download.

  On the other hand, the causes of abnormal data from specimens include abnormally high values due to disease, serum turbidity due to high cholesterol plasma, hemolysis due to erythrocyte membrane damage, effects of ascorbic acid due to medication, effects of high bilirubin plasma due to jaundice symptoms, etc. , There is an influence of data due to the color tone of the specimen and the elution of components from inside the red blood cells. Therefore, it is possible to confirm by looking at the degree of influence for each item from the degree of influence information on the coexisting substances in (5). Therefore, it automatically reads the barcode information of the reagents used, searches the server database from the reagent lot number information, and automatically downloads the influence data of coexisting substances when the relevant lot reagents are used. To.

  At present, in the laboratory, an operation format using a plurality of devices and a plurality of modules assuming backup and a large number of samples is becoming common. Thus, when performing accuracy control of a plurality of devices and modules, it is necessary to consider machine differences and differences between models. When searching and browsing the device correlation data in (6), the barcode information of the reagent used by the user is automatically read, the server database is searched from the reagent lot number information, and the relevant lot reagent is used. Automatically download impact data for coexisting substances.

  Cross contamination is the most common cause of data failure. Cross-contamination occurs between reagent probes and reaction cells. Usually, the apparatus is used repeatedly while the reagent probe and the cell are washed with water before and after use. However, if the residue stays rarely due to the composition or viscosity of the reagent, the abnormal reaction with the aspirated reagent causes data abnormality. In the case of the random access type analyzer, a special washing program function is provided to eliminate these effects, and the user has to set a program based on the contamination information provided by the reagent manufacturer. For the input, the combination of the affected item and the affected item, the selection of the reagent (first reagent or second reagent) to be affected, the name of the detergent to be used, and the amount of detergent consumed are entered. In this case, it is necessary to set the consumption amount of the detergent slightly larger than the consumption amounts of the first reagent and the second reagent, which are items that affect the cleaning effect. Furthermore, the total amount of the first reagent and the second reagent should not exceed the total reaction volume of the apparatus used. As described above, the user has to set and input a program in consideration of various factors such as the apparatus specifications based on the contamination information provided by the reagent manufacturer. Therefore, the contamination item search function (7) displays a list of cross contamination combination information in the server on the screen of the operation PC attached to the analyzer, and the cross between the reagent kits used by the user in the device. Automatically detect and extract the presence or absence of contamination combinations, and display a list on the screen. Furthermore, different symbols are used for display so that the setting / non-setting of the special cleaning program can be understood instantly. When there is an unset combination of programs, a function for automatically setting a special cleaning program is provided in the apparatus. When setting the program, the consumption amount of the detergent needs to be + α with respect to each reagent setting amount of the affecting item. This is because the consumption amount of the reagent is aspirated into the probe including a fixed dummy amount with respect to the set amount, so that the consumption amount is set amount + dummy amount. The + α amount is automatically calculated with respect to the set amount, allowing automatic setting input to the special cleaning program screen.

  The following effects can be obtained by the present invention. Downloadable information shows the reagent performance. For example, (1) Analytical parameters (2) Reproducibility of quality control substances (3) Stability of calibration results for about one week (4) Reagent linearity (5) Degree of influence of coexisting substances (6) Correlation with other models (7) Contamination information in reagent probe / reaction cell (8) Information in the instruction manual (booklet) attached to the reagent kit. Each time the lot number of quality control substances or reagents is updated, new data is uploaded and stored in the database, enabling many unspecified users to search and browse data and information suitable for their facilities. It is a feature.

Explanation of operation event information input. Network concept. Information download selection screen. Manufacturer name / item name selection screen. Quality control substance lot number selection screen. Quality control substance reproducibility display screen. Calibration stability display screen. Reagent linearity display screen. Coexisting substance influence degree display screen. Model correlation display screen. Cross-contamination display screen.

  The present invention uses a dedicated internet line to carry out various types of information using a dedicated Internet line when performing accuracy control of clinical laboratory automatic analyzers using patient specimens such as blood and urine, and analysis of causes when defective data appears. It is a system that collects and provides necessary information to the operator.

  FIG. 1 shows a system configuration diagram of an automatic analyzer for clinical examination.

  FIG. 2 shows the analysis parameters stored in the dedicated server 202 using the dedicated Internet line 201, the reproducibility of the quality control material, the stability of the calibration result (5 days), the reagent linearity, the degree of influence of the coexisting materials, Correlation with other models, contamination information in the reagent probe / reaction cell, various information in the instruction manual (letter book) attached to the reagent kit are searched, and on the screen of the PC 203 attached to the customer side automatic analyzer It is a system block diagram which can be confirmed. When a new reagent is released or updated to a new lot reagent or quality control material, new reproducibility data is sequentially input from the terminal 202 attached to the dedicated server to expand the database. The expanded information indicates the calibration factor value when the new lot reagent is updated, and the reproducibility result for the new lot quality control substance.

  FIG. 3 shows the information download screen of the PC 203 attached to the apparatus. When the user confirms the reproducibility of the quality control substance, the user selects the reproducibility 302 of the quality control substance on the screen and selects the execution key 308. Next, the screen shown in FIG. 4 is displayed. The reagent maker 401 and the item 402 are selected, and the execution 403 is selected and executed. Next, FIG. 5 showing a lot number list of quality control substances to be searched is displayed, and selection is performed with the radio button 501, and the execution key 502 is selected and executed. The apparatus grasps the lot number from the reagent barcode information currently used, and searches the server for reproducibility data measured with the lot reagent. FIG. 6 shows the reproducibility result of the quality control substance. The result shows an item name 601, a reagent manufacturer name 602, a standard solution concentration at calibration / unit 603, a reagent lot number 604, a standard solution lot number 605, and a standard solution name 606. The reproducibility result displays the average value, maximum value, minimum value, range, SD, and CV% for each selected quality control substance. The operator can confirm the degree of variation based on the evaluation of accuracy and the SD and CV% by comparing with the measurement result of the quality control sample measured during the routine at his / her facility.

  A patient sample data defect including a quality control substance includes a calibration defect due to reagent deterioration. Therefore, the operator needs to confirm the stability of calibration. When confirming the stability of the calibration result, the PC screen attached to the apparatus shown in FIG. 3 is displayed, and after selecting the calibration stability 303, the execution key 308 is selected. Thereafter, the screen shown in FIG. 4 is displayed. The reagent manufacturer 401 and the item 402 are selected and the execution key 403 is selected and executed. The apparatus grasps the lot number from the reagent barcode information currently used, and searches the server for reproducibility data measured with the lot reagent. After execution, it is possible to download data relating to the calibration stability of the corresponding item. FIG. 7 shows the calibration stability. The figure shows item name 701, manufacturer name 702, reagent lot number 703, standard solution lot number 704, standard solution concentration / unit 705, standard solution name 706, and calibration results 707 for five days. By clicking the black triangle mark in the reagent lot number frame 703 and the black triangle mark in the standard solution lot number frame 704, a pull-down menu is expanded, and other lot numbers can be selected and downloaded. The result 707 displays the absorbance data at the time of calibration as well as S1Abs and K value. Regarding the transition 708 of the primary wavelength absorbance of S1 and the subwavelength absorbance difference 709 from the primary wavelength of S2, a graph display is performed in order to easily display the degree of fluctuation. The change in the primary wavelength absorbance of S1 can confirm the influence of the denaturation and component deterioration of the reagent, the fading or discoloration of the reagent dye, and the subwavelength absorbance difference from the main wavelength of S2 can confirm the color development sensitivity.

  When the reagent component deteriorates, the reagent linearity decreases. When a sample near the upper limit of reagent linearity is measured, it may be assumed that satisfactory measurement cannot be performed if measurement is performed using a deteriorated reagent. In such a case, it is necessary to grasp the linearity of the reagent in advance. In such a case, the execution key is selected after selecting reagent linearity on the information download screen of FIG. Further, in FIG. 4, after selecting the manufacturer name 401 and the item 402, the execution key 403 is selected. The apparatus grasps the lot number from the reagent barcode information currently used, and searches the server for linearity data measured with the lot reagent. FIG. 8 shows the reagent linearity results. The displayed contents are item name 801, reagent manufacturer name 802, reagent lot number 803, standard solution lot number 804, standard solution concentration / unit 805 for calibration, standard solution name 806, manufacturer guarantee value 807 for linearity, actual measurement value A result 808 and a graph 809 are shown. By clicking the black triangle mark in the reagent lot number frame 803 and the black triangle mark in the standard solution lot number frame 804, a pull-down menu is expanded, and other lot numbers can be selected and downloaded. Compared with the results of the manufacturer's guarantee value and the actually measured value in the experiment, it is possible to confirm whether or not there is a margin for the reagent linearity. It can also be used as a material for determining whether a sample needs to be diluted when measuring a high-value sample during sample analysis. If it is already known from this result that the linear range has been exceeded, it is possible to carry out a measurement by performing a dilution operation in advance.

  The cause of data failure is not only from reagents but also from samples. In the case where jaundice is severe due to a disease, if it is desired to confirm the effect of the degree of serum yellow, the influence 305 of the coexisting substance is selected on the information download screen of FIG. Further, in FIG. 4, a manufacturer name 401 and an item 402 are selected and an execution key is selected. The apparatus grasps the lot number from the currently used reagent barcode information and searches the server for coexisting substance data measured with the lot reagent. A screen showing the influence degree of coexisting substances as shown in FIG. 9 opens. The degree of influence of coexisting substances varies depending on the reagent manufacturer and item. There are five types of coexisting substances: ascorbic acid 901, bilirubin C902, bilirubin F903, hemoglobin 904, and milk 905, and the degree of influence of plus error and minus error on the measured value at each added concentration can be understood. From this result, it is possible to know the additive substance and the amount to be added for each reagent, and help to investigate the cause of abnormal data.

  Depending on the facility, a plurality of main routine and emergency inspection devices may be used separately. Alternatively, there is a case where measurement is performed with an apparatus in which different modules are combined. In such a case, data divergence may occur due to a difference between machine differences and a difference between machine types. Therefore, it is possible to confirm the difference width between the two by confirming the device correlation data. The model correlation data 306 is selected from the information download selection screen of FIG. 3, and the execution key 308 is selected. Further, when the manufacturer name and item are selected in FIG. 4 and the execution key is selected, model correlation data as shown in FIG. 10 is displayed. Furthermore, by selecting the device name to be confirmed on the X-axis 1001 and the Y-axis 1002 using the pull-down key, the correlation data between the selected devices is displayed on the screen. On the screen, data for 50 to 60 samples and a total result 1003 are displayed. The tabulation result 1003 displays the correlation slope, intercept, X-axis, Y-axis average value, Sy / X, correlation coefficient, and graph. From this result, the difference width between the two models is known, and the allowable range of the difference between the models can be determined.

  The major cause of data failure is contamination in the reagent probe and reaction cell. The analyzer side has a special cleaning program function as a countermeasure. Therefore, first of all, it is important to understand the combination of reagent items that cause contamination, to take measures when using reagents that affect the device, and to confirm the necessity of setting a special cleaning program. Therefore, when the cross contamination information 307 is selected from the information download selection screen of FIG. 3 and the execution key 308 is selected and executed, the cross contamination list 1101 for all reagents and all items and items installed in the user apparatus are displayed. A list 1102 of cross-contamination occurring in the screen is displayed on the screen. The information display screen displays the items to be contaminated and received, the reagent manufacturer name, the degree of influence, the contaminated site, the cause of contamination, and the avoidance method. A circle in the left frame of the list 1102 indicates a combination for which an avoidance program is already set, and a mark ☆ indicates an unregistered combination. When the cross contamination avoidance selection key 1103 is selected in a state where the mark is highlighted by clicking on the mark, the avoidance program registration operation is automatically started. Registered contents are set as items to be affected and items to be received, reagent probe or reaction cell, and high alkali D, high carinone or water as an avoidance method. At that time, considering the cleaning effect, the detergent setting amount automatically determines the reagent amount (first reagent, second reagent) of the affected item, and automatically calculates 120% of the analysis parameter screen setting amount and the detergent consumption amount Set as.

  The reagent kit includes a reagent manual. In order to search the contents of the instruction manual in real time, the reagent instruction manual 307 is selected from the information download selection screen of FIG. 3, and the execution key 308 is selected and executed. Further, when the manufacturer name 401 and the item 402 are selected in FIG. 4 and the execution key is selected, the reagent instruction manual is displayed on the screen in the PDF format.

  The effects will be described below based on an example of search information.

<Regarding the reproducibility of quality control substances>
For the currently used reagent, the user reads the reagent lot number from the reagent barcode number, and the average, maximum, and minimum measurement results of quality control substances currently used on-time using that reagent. In addition to statistical data such as value, range, standard deviation, coefficient of variation, lot number of quality control material used for measurement, lot number of standard material used for calibration, lot number of reagent used for measurement, and valid It is possible to check the number of days and the expiration date after opening. Furthermore, when the lot number of quality control substances or reagents that have been used for measurement is changed, information on the values measured in the new lot is also uploaded to the dedicated server in sequence. The user can search the measurement result of the quality control substance of the lot number currently used in his / her facility, such as the lot number of the quality control substance used, the lot number of the reagent, the effective days and the expiration date of the reagent, etc. Based on this information, it is possible to easily investigate the causes such as the presence or absence of the influence of reagent deterioration and the problem of poor handling of quality control substances.

<Calibration stability>
Approximately one week of main wavelength, subwavelength absorbance data, reagent lot number, standard lot number, concentration setting value, and calibration results measured by the same model used by the user It is possible to search for information on (S1Abs, K value). In many cases, the quality control material data failure is caused by a defect in the calibration result. Therefore, by confirming the main wavelength / sub-wavelength measurement absorbance at the time of calibration for 5 days, the degree of variation in calibration absorbance can be understood and compared with the results measured in real time. It is possible to determine whether is normal or abnormal. About 1 week of recorded content corresponds to the consumption cycle of 1 bottle of reagent. Compared with the calibration result of about 1 week, the fluctuation of day and the rise or fall of absorbance value due to reagent deterioration. As a result, it is possible to determine whether the result performed in real time is acceptable. Because clinical laboratory reagents are usually stored and stored in the reagent cooler of the device with the lid open, it is necessary to carefully check for reagent deterioration, and the deterioration speed differs depending on the individual items. The ability to confirm the data is abnormally significant. The dedicated server contains the results of measurements with reagents of all lot numbers currently on the market, so users are attached to the top of reagent bottles when searching for calibration data Since the bar code information is automatically read and searched, it is possible to save the trouble of input and to eliminate careless errors such as input errors.

<Regarding reagent linearity>
When measuring an abnormally high patient sample, it is possible to determine whether the measurement is correct. The analyzer checks whether the change in absorbance is within the set value within the photometric point range determined by the analysis parameters. However, the original reagent linearity range is narrowed due to deterioration of the reagent components. Sometimes. Although the abnormal high value data is checked by using the limit absorbance check function of the analyzer, this method cannot be surely checked unless a correct set value is input to the analysis parameter screen. Therefore, if the Chuc value is not entered, it may be reported as it is regardless of the abnormal value. This function makes it possible to cover lack of checks by utilizing the linearity guarantee value of the reagent manufacturer.

<About coexisting substance information>
Specimen-derived data abnormalities include abnormally high values due to disease, serum turbidity due to high cholesterol plasma, hemolysis due to erythrocyte membrane breakage, effects of ascorbic acid due to medication, effects of high bilirubin plasma due to jaundice symptoms, etc. There is an influence of data by the color tone and elution of components from the inside of red blood cells. Even if the degree of influence is the same item, the tendency is often different for different reagent manufacturers. Since it becomes possible to search the influence degree information of coexisting substances for each reagent manufacturer and item, it becomes possible to verify the cause investigation when abnormal data occurs and to estimate the true value to some extent from the influence degree. Furthermore, if the degree of coexisting substances is known in advance, it can be seen that, for example, if hemolysis occurs during a blood sampling procedure, it will affect the subsequent measurement test. It is also possible to prepare so as not to hinder the inspection.

<About model correlation data>
When managing the accuracy of multiple devices and modules, it is necessary to consider machine differences and differences between models. By searching and browsing the device correlation data, it is possible to objectively compare and judge the allowable range of machine differences between devices and modules by searching for data by reagent manufacturer and item used by the user. .

<About cross-contamination information>
Conventionally, the user has to manually input an apparatus operation unit special cleaning program in consideration of various factors such as a reagent dispensing amount based on a huge amount of cross-contamination information provided by a reagent manufacturer. The cross-contamination item search function makes it possible to check the combination of contamination among all manufacturers by downloading information, and the user has already registered a special cleaning program to avoid cross-contamination. By automating the process, it is possible to eliminate the labor so far, which greatly contributes to the reduction of data defects.

<Regarding the reagent instruction manual>
With the PDF file download function, you can download the latest version of the manual on the PC screen attached to the device, so that you can instantly view the latest version of the reagent book. You can check various technical information. The certificate attached to the reagent contains various data such as content name and amount, chemical reaction formula, reproducibility, bottle capacity, expiration date, stability after opening, handling method, disposal method, skin contact Various information such as how to deal with time is described. Since the paper-based manual may be discarded or lost while in use, electronic data download browsing is highly useful.

1 Sample Cup 2 Sample Barcode Reader 3 Computer 4 Interface 5 Sample Dispensing Probe 6 Reaction Container 7 Sample Pump 8 Constant Temperature Bath 9 Reaction Disk 10 Reagent Dispensing Probe 11 Reagent Pump 12 Reagent Bottle 13 Stirrer 14 Light Source 15 Multiple Wavelength photometer 16 Keyboard 17 Printer 18 CRT screen 19 Reagent bar coat reader 20 Reaction vessel cleaning system 24 FD drive 25 HD

Claims (7)

An automatic analysis system comprising a server for storing information including quality control substance data, reagent related data, and information necessary for a special cleaning program, and a control computer connected to the server via a network line. ,
The automatic analysis system, wherein the control computer has a function of searching for information stored in the server based on reagent identification information. The automatic analysis system according to claim 1,
The automatic analysis system, wherein the reagent identification information is specified based on a reagent identifier provided in a reagent container. The automatic analysis system according to claim 1,
The automatic search system is characterized in that the searching function is performed by selecting identification information of a quality control substance on a screen of the control computer. The automatic analysis system according to claim 1,
The automatic search system is characterized in that the searching function is performed by selecting a lot number of a reagent and a lot number of a calibrator used on the screen of the control computer. The automatic analysis system according to claim 1,
The automatic analysis system is characterized in that the searching function is performed by selecting a lot number of a reagent used on the screen of the control computer. The automatic analysis system according to claim 1,
The automatic search system is characterized in that the search function is performed by selecting an analyzer and model set on the X axis and Y axis of the correlation diagram on the screen of the control computer. The automatic analysis system according to claim 1,
When searching for cross-contamination information, there is a function to display all combinations of all reagents and a function to automatically extract and display combinations that occur between reagents installed in the device. / Has a setting that makes it possible to instantly determine whether it has not been set, and has a function for automatically entering and setting a special cleaning program. When determining the amount of detergent, it is automatically calculated based on the amount of reagent that gives contamination. And an automatic analysis system characterized by having a setting function.

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