JP2011530540A - テトラヒドロビオプテリンを含有する医薬剤形 - Google Patents
テトラヒドロビオプテリンを含有する医薬剤形 Download PDFInfo
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- JP2011530540A JP2011530540A JP2011522346A JP2011522346A JP2011530540A JP 2011530540 A JP2011530540 A JP 2011530540A JP 2011522346 A JP2011522346 A JP 2011522346A JP 2011522346 A JP2011522346 A JP 2011522346A JP 2011530540 A JP2011530540 A JP 2011530540A
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- JP
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- Prior art keywords
- tetrahydrobiopterin
- dosage form
- pharmaceutical dosage
- aqueous solution
- metabolic precursor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 229960004617 sapropterin Drugs 0.000 title claims abstract description 117
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- 235000002906 tartaric acid Nutrition 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000012756 tartrazine Nutrition 0.000 description 1
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- 229960000943 tartrazine Drugs 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000004797 therapeutic response Effects 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
- 235000010215 titanium dioxide Nutrition 0.000 description 1
- KBPHJBAIARWVSC-XQIHNALSSA-N trans-lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C KBPHJBAIARWVSC-XQIHNALSSA-N 0.000 description 1
- 230000002463 transducing effect Effects 0.000 description 1
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- 235000013976 turmeric Nutrition 0.000 description 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 229910021642 ultra pure water Inorganic materials 0.000 description 1
- 239000012498 ultrapure water Substances 0.000 description 1
- 235000012141 vanillin Nutrition 0.000 description 1
- MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 description 1
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ATA1254/2008 | 2008-08-12 | ||
| AT12542008 | 2008-08-12 | ||
| PCT/AT2009/000306 WO2010017570A2 (de) | 2008-08-12 | 2009-08-07 | Pharmazeutische darreichungsform enthaltend tetrahydrobiopterin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011530540A true JP2011530540A (ja) | 2011-12-22 |
| JP2011530540A5 JP2011530540A5 (enExample) | 2012-06-07 |
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| JP2011522346A Pending JP2011530540A (ja) | 2008-08-12 | 2009-08-07 | テトラヒドロビオプテリンを含有する医薬剤形 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20110144117A1 (enExample) |
| EP (1) | EP2309983B1 (enExample) |
| JP (1) | JP2011530540A (enExample) |
| ES (1) | ES2736730T3 (enExample) |
| PL (1) | PL2309983T3 (enExample) |
| RU (1) | RU2011109210A (enExample) |
| TR (1) | TR201910287T4 (enExample) |
| WO (1) | WO2010017570A2 (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016029096A (ja) * | 2013-01-10 | 2016-03-03 | ニュートリショナル セラピューティクス インコーポレイテッド ディー／ビー／エーエヌティーアイ インコーポレイテッド | 健康の維持ならびに急性および慢性障害の治療のための脂質サプリメントを含有するチュアブルウエハース |
| JP2017509623A (ja) * | 2014-03-31 | 2017-04-06 | ヴァソファーム ゲーエムベーハー | ビオプテリン誘導体を含む固体薬学的組成物およびそのような組成物の使用 |
| JP2020068734A (ja) * | 2018-11-01 | 2020-05-07 | 国立大学法人東京工業大学 | Ｓｐｒをコードするポリヌクレオチドを含む組換えベクター、及びそれを含む組成物 |
| JP2020532535A (ja) * | 2017-09-01 | 2020-11-12 | ピーティーシー セラピューティクス エムピー，インコーポレイテッド | セピアプテリンを含む医薬組成物及びその使用 |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL266955B2 (en) | 2016-11-29 | 2023-09-01 | Ptc Therapeutics Mp Inc | Polymorphs of spiafatrin and its salts |
| WO2018102314A1 (en) | 2016-11-29 | 2018-06-07 | Censa Pharmaceuticals Inc. | Polymorphic form of sepiapterin |
| SMT202400430T1 (it) | 2018-05-30 | 2024-11-15 | Ptc Therapeutics Mp Inc | Somministrazione di sepiapterina, senza alcun alimento, per uso in un metodo per incrementare l’esposizione plasmatica di sepiapterina |
| EP3801534A4 (en) | 2018-05-30 | 2022-03-16 | PTC Therapeutics MP, Inc. | COMPOSITIONS AND METHODS TO INCREASE TETRAHYDROBIOPTERIN PLASMA EXPOSURE |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005107759A1 (ja) * | 2004-05-11 | 2005-11-17 | Daiichi Asubo Pharma Co., Ltd. | Ｂｈ４反応性高フェニルアラニン血症治療剤 |
| US20060211701A1 (en) * | 2002-12-20 | 2006-09-21 | Ania Muntau-Heger | Use of von tetrahydrobiopterine derivatives in the treatment and nutrition of patients with amino acid metabolic disorders |
| WO2008128049A2 (en) * | 2007-04-11 | 2008-10-23 | Biomarin Pharmaceutical Inc. | Methods of administering tetrahydrobiopterin, associated compositions, and methods of measuring |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61277618A (ja) * | 1985-06-04 | 1986-12-08 | Suntory Ltd | 自閉症治療剤 |
| JP2588191B2 (ja) * | 1987-04-24 | 1997-03-05 | サントリー株式会社 | 悪性腫瘍および重症ウイルス感染症に伴う神経症状を改善するための治療剤 |
| EP2436379A1 (en) * | 2004-11-17 | 2012-04-04 | BioMarin Pharmaceutical Inc. | Stable tablet formulation |
| US20060188492A1 (en) * | 2005-01-13 | 2006-08-24 | Chronorx Llc, An Alaska Limited Liability Company | Topical management of ocular and periocular conditions |
| AU2006245770A1 (en) * | 2005-05-11 | 2006-11-16 | Nycomed Gmbh | Combination of the PDE4 inhibitor roflumilast and a tetrahydrobiopterin derivative |
-
2009
- 2009-08-07 ES ES09775591T patent/ES2736730T3/es active Active
- 2009-08-07 PL PL09775591T patent/PL2309983T3/pl unknown
- 2009-08-07 RU RU2011109210/15A patent/RU2011109210A/ru not_active Application Discontinuation
- 2009-08-07 WO PCT/AT2009/000306 patent/WO2010017570A2/de not_active Ceased
- 2009-08-07 TR TR2019/10287T patent/TR201910287T4/tr unknown
- 2009-08-07 JP JP2011522346A patent/JP2011530540A/ja active Pending
- 2009-08-07 US US13/058,625 patent/US20110144117A1/en not_active Abandoned
- 2009-08-07 EP EP09775591.2A patent/EP2309983B1/de active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060211701A1 (en) * | 2002-12-20 | 2006-09-21 | Ania Muntau-Heger | Use of von tetrahydrobiopterine derivatives in the treatment and nutrition of patients with amino acid metabolic disorders |
| WO2005107759A1 (ja) * | 2004-05-11 | 2005-11-17 | Daiichi Asubo Pharma Co., Ltd. | Ｂｈ４反応性高フェニルアラニン血症治療剤 |
| WO2008128049A2 (en) * | 2007-04-11 | 2008-10-23 | Biomarin Pharmaceutical Inc. | Methods of administering tetrahydrobiopterin, associated compositions, and methods of measuring |
Non-Patent Citations (3)
| Title |
|---|
| JPN6013051901; ＭＵＮＴＡＵ， Ａ．Ｃ． ｅｔ ａｌ．: Ｔｈｅ Ｎｅｗ Ｅｎｇｌａｎｄ Ｊｏｕｒｎａｌ ｏｆ Ｍｅｄｉｃｉｎｅ Ｖｏｌ．３４７， Ｎｏ．２６, 2002, ｐ．２１２２-２１３２ * |
| JPN6013051902; ＶＡＬＥＮＴ， Ｓ． ｅｔ ａｌ．: Ｔｈｅ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｊｏｕｒｎａｌ ｏｆ Ｂｉｏｃｈｅｍｉｓｔｒｙ ＆ Ｃｅｌｌ Ｂｉｏｌｏｇｙ Ｖｏｌ．３６, 2004, ｐ．１２６６-１２８０ * |
| JPN6013051903; ＶＡＬＥＮＴ， Ｓ． ｅｔ ａｌ．: Ｔｈｅ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｊｏｕｒｎａｌ ｏｆ Ｂｉｏｃｈｅｍｉｓｔｒｙ ＆ Ｃｅｌｌ Ｂｉｏｌｏｇｙ Ｖｏｌ．３８, 2006, ｐ．１７８６-１７９３ * |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016029096A (ja) * | 2013-01-10 | 2016-03-03 | ニュートリショナル セラピューティクス インコーポレイテッド ディー／ビー／エーエヌティーアイ インコーポレイテッド | 健康の維持ならびに急性および慢性障害の治療のための脂質サプリメントを含有するチュアブルウエハース |
| JP2017509623A (ja) * | 2014-03-31 | 2017-04-06 | ヴァソファーム ゲーエムベーハー | ビオプテリン誘導体を含む固体薬学的組成物およびそのような組成物の使用 |
| JP2019194227A (ja) * | 2014-03-31 | 2019-11-07 | ヴァソファーム ゲーエムベーハー | ビオプテリン誘導体を含む固体薬学的組成物およびそのような組成物の使用 |
| US10493075B2 (en) | 2014-03-31 | 2019-12-03 | Vasopharm Gmbh | Solid pharmaceutical compositions comprising biopterin derivatives and uses of such compositions |
| US10925877B2 (en) | 2014-03-31 | 2021-02-23 | Vasopharm Gmbh | Solid pharmaceutical compositions comprising biopterin derivatives and uses of such compositions |
| US11717522B2 (en) | 2014-03-31 | 2023-08-08 | Vasopharm Gmbh | Solid pharmaceutical compositions comprising biopterin derivatives and uses of such compositions |
| JP2020532535A (ja) * | 2017-09-01 | 2020-11-12 | ピーティーシー セラピューティクス エムピー，インコーポレイテッド | セピアプテリンを含む医薬組成物及びその使用 |
| US11752154B2 (en) | 2017-09-01 | 2023-09-12 | Ptc Therapeutics Mp, Inc. | Pharmaceutical compositions comprising sepiapterin and uses thereof |
| US12213982B2 (en) | 2017-09-01 | 2025-02-04 | Ptc Therapeutics Mp, Inc. | Pharmaceutical compositions comprising sepiapterin and uses thereof |
| JP2020068734A (ja) * | 2018-11-01 | 2020-05-07 | 国立大学法人東京工業大学 | Ｓｐｒをコードするポリヌクレオチドを含む組換えベクター、及びそれを含む組成物 |
| JP2023041849A (ja) * | 2018-11-01 | 2023-03-24 | 宏 一瀬 | Ｓｐｒをコードするポリヌクレオチドを含む組換えベクター、及びそれを含む組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20110144117A1 (en) | 2011-06-16 |
| WO2010017570A2 (de) | 2010-02-18 |
| EP2309983B1 (de) | 2019-04-24 |
| RU2011109210A (ru) | 2012-09-20 |
| PL2309983T3 (pl) | 2019-09-30 |
| ES2736730T3 (es) | 2020-01-07 |
| EP2309983A2 (de) | 2011-04-20 |
| TR201910287T4 (tr) | 2019-07-22 |
| WO2010017570A3 (de) | 2010-08-05 |
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