JP2011529085A - 抗ウイルス化合物 - Google Patents

抗ウイルス化合物 Download PDF

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Publication number
JP2011529085A
JP2011529085A JP2011520237A JP2011520237A JP2011529085A JP 2011529085 A JP2011529085 A JP 2011529085A JP 2011520237 A JP2011520237 A JP 2011520237A JP 2011520237 A JP2011520237 A JP 2011520237A JP 2011529085 A JP2011529085 A JP 2011529085A
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JP
Japan
Prior art keywords
optionally substituted
compound
mmol
reaction
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2011520237A
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English (en)
Japanese (ja)
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JP2011529085A5 (https=
Inventor
エバンゲロス アクトーディアナキス，
アジム アラン セレビ，
チーミン ドゥ，
サルマン ワイ． ジャブリ，
ハオラン ジン，
チョン ユー． キム，
チアヤオ リ，
サムエル イー． メトボ，
マイケル アール． ミッシュ，
バートン タブリュー． フィリップス，
ジョセフ エイチ． サウギア，
チェン−ユ ヤン，
カタリン セバスチャン ゾンテ，
Original Assignee
ギリアード サイエンシーズ， インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ギリアード サイエンシーズ， インコーポレイテッド filed Critical ギリアード サイエンシーズ， インコーポレイテッド
Publication of JP2011529085A publication Critical patent/JP2011529085A/ja
Publication of JP2011529085A5 publication Critical patent/JP2011529085A5/ja
Withdrawn legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/16—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/16—Peri-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2011520237A 2008-07-25 2009-07-24 抗ウイルス化合物 Withdrawn JP2011529085A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US8385508P 2008-07-25 2008-07-25
US61/083,855 2008-07-25
US14768109P 2009-01-27 2009-01-27
US61/147,681 2009-01-27
US22011009P 2009-06-24 2009-06-24
US61/220,110 2009-06-24
PCT/US2009/051741 WO2010011959A1 (en) 2008-07-25 2009-07-24 Antiviral compounds

Publications (2)

Publication Number Publication Date
JP2011529085A true JP2011529085A (ja) 2011-12-01
JP2011529085A5 JP2011529085A5 (https=) 2012-09-06

Family

ID=41211919

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011520237A Withdrawn JP2011529085A (ja) 2008-07-25 2009-07-24 抗ウイルス化合物

Country Status (8)

Country Link
US (1) US7998950B2 (https=)
EP (1) EP2321319B1 (https=)
JP (1) JP2011529085A (https=)
AR (1) AR072534A1 (https=)
AT (1) ATE549335T1 (https=)
AU (1) AU2009273844A1 (https=)
TW (1) TW201016698A (https=)
WO (1) WO2010011959A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014034523A (ja) * 2012-08-07 2014-02-24 Manac Inc モノまたはジハロゲノピリジルアミン類の製造方法

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110223131A1 (en) * 2010-02-24 2011-09-15 Gilead Sciences, Inc. Antiviral compounds
DK3236972T3 (en) 2014-12-26 2021-10-04 Univ Emory Antivirale N4-hydroxycytidin-derivativer
CN104628650A (zh) * 2015-02-02 2015-05-20 西安近代化学研究所 1-(3-氨丙基)-2-甲基咪唑的制备方法
JP6804790B1 (ja) 2017-12-07 2020-12-23 エモリー ユニバーシティー Ｎ４−ヒドロキシシチジンおよび誘導体ならびにそれらに関連する抗ウイルス用途
JP2024536868A (ja) 2021-09-27 2024-10-08 ヤンセン ファーマシューティカ エヌ．ベー． ベンズイミダゾール及びアザベンズイミダゾールｉｌ－１７阻害剤化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR056918A1 (es) 2005-01-10 2007-11-07 Tibotec Pharm Ltd 2-oxo-3-ciano-1,6a-diaza-tetrahidro-fluorantenos 1,5,6-sustituidos, proceso de preparacion del compuesto y composicion farmaceutica
EP1910356A4 (en) 2005-08-04 2009-10-21 Smithkline Beecham Corp HIV integrase
GB0707708D0 (en) 2007-04-20 2007-05-30 Glaxo Group Ltd Compounds
EP2005995A1 (en) 2007-06-22 2008-12-24 Glaxo Group Limited Heterocyclic compounds for the treatment of tuberculosis

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014034523A (ja) * 2012-08-07 2014-02-24 Manac Inc モノまたはジハロゲノピリジルアミン類の製造方法

Also Published As

Publication number Publication date
ATE549335T1 (de) 2012-03-15
AR072534A1 (es) 2010-09-01
US7998950B2 (en) 2011-08-16
TW201016698A (en) 2010-05-01
US20100022508A1 (en) 2010-01-28
EP2321319B1 (en) 2012-03-14
WO2010011959A1 (en) 2010-01-28
EP2321319A1 (en) 2011-05-18
AU2009273844A1 (en) 2010-01-28

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