JP2011527575A - Notchシグナル伝達のインヒビターでの処置に感受性であるがんの同定 - Google Patents
Notchシグナル伝達のインヒビターでの処置に感受性であるがんの同定 Download PDFInfo
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Applications Claiming Priority (5)
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| US8012208P | 2008-07-11 | 2008-07-11 | |
| US61/080,122 | 2008-07-11 | ||
| US12/360,790 US7544476B1 (en) | 2008-07-11 | 2009-01-27 | Identifying cancers sensitive to treatment with inhibitors of notch signaling |
| US12/360,790 | 2009-01-27 | ||
| PCT/US2009/045479 WO2010005644A1 (en) | 2008-07-11 | 2009-05-28 | Identifying cancers sensitive to treatment with inhibitors of notch signaling |
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| JP2011527575A true JP2011527575A (ja) | 2011-11-04 |
| JP2011527575A5 JP2011527575A5 (enExample) | 2012-07-12 |
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| JP2011517443A Pending JP2011527575A (ja) | 2008-07-11 | 2009-05-28 | Notchシグナル伝達のインヒビターでの処置に感受性であるがんの同定 |
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| US (1) | US7544476B1 (enExample) |
| EP (1) | EP2313526A4 (enExample) |
| JP (1) | JP2011527575A (enExample) |
| AU (1) | AU2009269081A1 (enExample) |
| CA (1) | CA2730215A1 (enExample) |
| WO (1) | WO2010005644A1 (enExample) |
Families Citing this family (7)
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|---|---|---|---|---|
| WO2007136856A2 (en) * | 2006-05-19 | 2007-11-29 | The Johns Hopkins University | Heyl as a therapeutic target and a diagnostic marker for neoplasia and uses therefor |
| WO2008076960A2 (en) | 2006-12-18 | 2008-06-26 | Genentech, Inc. | Antagonist anti-notch3 antibodies and their use in the prevention and treatment of notch3-related diseases |
| US20120082659A1 (en) * | 2007-10-02 | 2012-04-05 | Hartmut Land | Methods And Compositions Related To Synergistic Responses To Oncogenic Mutations |
| DK2935330T3 (da) | 2012-12-19 | 2019-07-22 | Aveo Pharmaceuticals Inc | Anti-notch3-antistoffer |
| EP3448420B1 (en) | 2016-04-29 | 2022-09-14 | Aveo Pharmaceuticals, Inc. | Anti-notch3 antibody |
| EP3462349A1 (en) * | 2017-10-02 | 2019-04-03 | Koninklijke Philips N.V. | Assessment of notch cellular signaling pathway activity using mathematical modelling of target gene expression |
| EP3502279A1 (en) | 2017-12-20 | 2019-06-26 | Koninklijke Philips N.V. | Assessment of mapk-ap 1 cellular signaling pathway activity using mathematical modelling of target gene expression |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006092062A1 (en) * | 2005-03-04 | 2006-09-08 | The Hospital For Sick Children | Methods for cancer prognosis |
| WO2007070671A2 (en) * | 2005-12-16 | 2007-06-21 | Regeneron Pharmaceuticals, Inc. | Therapeutic methods for inhibiting tumor growth with dll4 antagonists |
| WO2007136856A2 (en) * | 2006-05-19 | 2007-11-29 | The Johns Hopkins University | Heyl as a therapeutic target and a diagnostic marker for neoplasia and uses therefor |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2006047878A1 (en) | 2004-11-03 | 2006-05-11 | British Columbia Cancer Agency Branch | Cancer therapeutics and methods for their use |
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2009
- 2009-01-27 US US12/360,790 patent/US7544476B1/en not_active Expired - Fee Related
- 2009-05-28 EP EP09794862A patent/EP2313526A4/en not_active Withdrawn
- 2009-05-28 JP JP2011517443A patent/JP2011527575A/ja active Pending
- 2009-05-28 WO PCT/US2009/045479 patent/WO2010005644A1/en not_active Ceased
- 2009-05-28 AU AU2009269081A patent/AU2009269081A1/en not_active Abandoned
- 2009-05-28 CA CA2730215A patent/CA2730215A1/en not_active Abandoned
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006092062A1 (en) * | 2005-03-04 | 2006-09-08 | The Hospital For Sick Children | Methods for cancer prognosis |
| WO2007070671A2 (en) * | 2005-12-16 | 2007-06-21 | Regeneron Pharmaceuticals, Inc. | Therapeutic methods for inhibiting tumor growth with dll4 antagonists |
| WO2007136856A2 (en) * | 2006-05-19 | 2007-11-29 | The Johns Hopkins University | Heyl as a therapeutic target and a diagnostic marker for neoplasia and uses therefor |
Non-Patent Citations (1)
| Title |
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| JPN6013064284; Current cancer drug targets. 2006, Vol.6, No.4, p.313-323 * |
Also Published As
| Publication number | Publication date |
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| CA2730215A1 (en) | 2010-01-14 |
| AU2009269081A1 (en) | 2010-01-14 |
| EP2313526A4 (en) | 2011-08-31 |
| EP2313526A1 (en) | 2011-04-27 |
| WO2010005644A1 (en) | 2010-01-14 |
| US7544476B1 (en) | 2009-06-09 |
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