JP2011525354A5 - - Google Patents

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JP2011525354A5
JP2011525354A5 JP2011514065A JP2011514065A JP2011525354A5 JP 2011525354 A5 JP2011525354 A5 JP 2011525354A5 JP 2011514065 A JP2011514065 A JP 2011514065A JP 2011514065 A JP2011514065 A JP 2011514065A JP 2011525354 A5 JP2011525354 A5 JP 2011525354A5
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Japan
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gln
thr
ala
arg
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JP2011514065A
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JP2011525354A (ja
JP5711118B2 (ja
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Priority claimed from PCT/EP2009/057925 external-priority patent/WO2009156456A1/en
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JP2011514065A 2008-06-24 2009-06-24 所与の標的に対してアフィニティーを有するhNGALおよび類縁タンパク質のムテイン Active JP5711118B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7517508P 2008-06-24 2008-06-24
US61/075,175 2008-06-24
PCT/EP2009/057925 WO2009156456A1 (en) 2008-06-24 2009-06-24 Muteins of hngal and related proteins with affinity for a given target

Publications (3)

Publication Number Publication Date
JP2011525354A JP2011525354A (ja) 2011-09-22
JP2011525354A5 true JP2011525354A5 (https=) 2014-12-04
JP5711118B2 JP5711118B2 (ja) 2015-04-30

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ID=41256028

Family Applications (1)

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JP2011514065A Active JP5711118B2 (ja) 2008-06-24 2009-06-24 所与の標的に対してアフィニティーを有するhNGALおよび類縁タンパク質のムテイン

Country Status (7)

Country Link
US (2) US8420051B2 (https=)
EP (2) EP3381933B1 (https=)
JP (1) JP5711118B2 (https=)
AU (1) AU2009264214B2 (https=)
CA (1) CA2729322C (https=)
DK (1) DK3381933T3 (https=)
WO (1) WO2009156456A1 (https=)

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CA2724384A1 (en) 2008-05-15 2009-11-19 Transmolecular, Inc. Treatment of metastatic tumors
DK3381933T3 (da) * 2008-06-24 2020-08-03 Technische Universität München Muteiner af hngal og relaterede proteiner med affinitet til et givet mål
RU2707126C2 (ru) * 2009-12-07 2019-11-22 Пирис Аг МУТЕИНЫ ЛИПОКАЛИНА 2 ЧЕЛОВЕКА (Lcn2, hNGAL) С АФФИННОСТЬЮ ДЛЯ ОПРЕДЕЛЕННОЙ МИШЕНИ
CN102844044B (zh) 2010-02-04 2016-10-26 摩尔弗泰克有限公司 氯毒素多肽和结合物及其应用
EP3165533B1 (en) 2010-05-11 2020-04-08 Fred Hutchinson Cancer Research Center Chlorotoxin variants, conjugates and methods for their use
WO2011149962A1 (en) 2010-05-24 2011-12-01 The Trustees Of Columbia University In The City Of New York Mutant ngal proteins and uses thereof
EP3299386A1 (en) * 2010-08-16 2018-03-28 Pieris Pharmaceuticals GmbH Binding proteins for hepcidin
AU2011331232B2 (en) * 2010-11-15 2015-05-07 Pieris Ag Muteins of human lipocalin 2 with affinity for Glypican-3 (GPC3)
US9758554B2 (en) 2012-01-31 2017-09-12 Technische Universitaet Muenchen Muteins of α1m lipocalin and method of production therefor
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US10526384B2 (en) 2012-11-19 2020-01-07 Pieris Pharmaceuticals Gmbh Interleukin-17A-specific and interleukin-23-specific binding polypeptides and uses thereof
EP2925337B1 (en) 2012-11-21 2019-07-03 The Trustees of Columbia University in the City of New York Mutant ngal proteins and uses thereof
CA2913029A1 (en) * 2012-12-10 2014-06-19 Fred Hutchinson Cancer Research Center Lipocalin fusion partners
US11559580B1 (en) 2013-09-17 2023-01-24 Blaze Bioscience, Inc. Tissue-homing peptide conjugates and methods of use thereof
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JP6839087B2 (ja) * 2015-01-28 2021-03-03 ピエリス ファーマシューティカルズ ゲーエムベーハー 血管新生に特異的な新規のタンパク質
CR20170425A (es) 2015-02-18 2017-11-22 Sanofi Sa Nuevas proteínas específicas para pioverdina y pioquelina
JP6783797B2 (ja) * 2015-05-04 2020-11-11 ピエリス ファーマシューティカルズ ゲーエムベーハー 抗がん融合ポリペプチド
CN114573680A (zh) 2015-05-04 2022-06-03 皮里斯制药有限公司 Cd137特异性的蛋白
MX2017014730A (es) 2015-05-18 2018-06-28 Pieris Pharmaceuticals Gmbh Muteinas de lipocalina 2 humana con afinidad por glipicano-3 (gpc3).
EP3298030B1 (en) 2015-05-18 2023-01-18 Pieris Pharmaceuticals GmbH Anti-cancer fusion polypeptide
EP3115066A1 (en) 2015-07-07 2017-01-11 Technische Universität München Novel psma-specific binding proteins
EP3115371A1 (en) 2015-07-07 2017-01-11 Sanofi Fusion molecules
CN108699162A (zh) 2015-11-30 2018-10-23 皮里斯澳大利亚有限公司 新型抗血管生成融合多肽
TW201725212A (zh) 2015-12-10 2017-07-16 第一三共股份有限公司 特異性於降鈣素基因相關胜肽的新穎蛋白
US12048732B2 (en) 2016-04-15 2024-07-30 Blaze Bioscience, Inc. Methods of treating breast cancer
US11813336B2 (en) * 2016-05-04 2023-11-14 Navigo Proteins Gmbh Targeted compounds for the site-specific coupling of chemical moieties comprising a peptide linker
EP3503930B1 (en) 2016-08-29 2024-12-11 Fred Hutchinson Cancer Center Chelating platform for delivery of radionuclides

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DK3381933T3 (da) * 2008-06-24 2020-08-03 Technische Universität München Muteiner af hngal og relaterede proteiner med affinitet til et givet mål

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