JP2011523849A5 - - Google Patents
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- Publication number
- JP2011523849A5 JP2011523849A5 JP2011510744A JP2011510744A JP2011523849A5 JP 2011523849 A5 JP2011523849 A5 JP 2011523849A5 JP 2011510744 A JP2011510744 A JP 2011510744A JP 2011510744 A JP2011510744 A JP 2011510744A JP 2011523849 A5 JP2011523849 A5 JP 2011523849A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- binding protein
- binding
- binding fragment
- fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000023732 binding proteins Human genes 0.000 claims 42
- 108091008324 binding proteins Proteins 0.000 claims 42
- 239000000427 antigen Substances 0.000 claims 35
- 102000036639 antigens Human genes 0.000 claims 35
- 108091007433 antigens Proteins 0.000 claims 35
- 239000012634 fragment Substances 0.000 claims 35
- 239000002773 nucleotide Substances 0.000 claims 9
- 125000003729 nucleotide group Chemical group 0.000 claims 9
- 102000025171 antigen binding proteins Human genes 0.000 claims 8
- 108091000831 antigen binding proteins Proteins 0.000 claims 8
- 102100030704 Interleukin-21 Human genes 0.000 claims 6
- 108010017411 Interleukin-21 Receptors Proteins 0.000 claims 6
- 102000004527 Interleukin-21 Receptors Human genes 0.000 claims 6
- 108010074108 interleukin-21 Proteins 0.000 claims 6
- 210000004027 cell Anatomy 0.000 claims 5
- 101001010593 Homo sapiens Interleukin-21 receptor Proteins 0.000 claims 4
- 230000001404 mediated effect Effects 0.000 claims 4
- 125000003275 alpha amino acid group Chemical group 0.000 claims 3
- 230000035755 proliferation Effects 0.000 claims 3
- 102100035360 Cerebellar degeneration-related antigen 1 Human genes 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 210000003719 b-lymphocyte Anatomy 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 238000009007 Diagnostic Kit Methods 0.000 claims 1
- 101100005713 Homo sapiens CD4 gene Proteins 0.000 claims 1
- 230000004663 cell proliferation Effects 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5550008P | 2008-05-23 | 2008-05-23 | |
| US61/055,500 | 2008-05-23 | ||
| PCT/US2009/045182 WO2009143523A1 (en) | 2008-05-23 | 2009-05-26 | Interleukin-21 receptor binding proteins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011523849A JP2011523849A (ja) | 2011-08-25 |
| JP2011523849A5 true JP2011523849A5 (cg-RX-API-DMAC7.html) | 2012-07-12 |
Family
ID=41112652
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011510744A Pending JP2011523849A (ja) | 2008-05-23 | 2009-05-26 | インターロイキン−２１受容体結合性タンパク質 |
Country Status (20)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6057128A (en) | 1998-03-17 | 2000-05-02 | Genetics Institute, Inc. | MU-1, member of the cytokine receptor family |
| EP2518084B1 (en) * | 2009-12-25 | 2016-11-30 | Sekisui Medical Co., Ltd. | Method for measuring human insulin and measurement reagent |
| US8846603B2 (en) * | 2010-03-12 | 2014-09-30 | Synageva Biopharma Corp. | NPP1 fusion proteins |
| US9309318B2 (en) * | 2012-10-17 | 2016-04-12 | Amgen, Inc. | Compositions relating to anti-IL-21 receptor antibodies |
| WO2018045273A2 (en) * | 2016-09-02 | 2018-03-08 | The Brigham And Women's Hospital, Inc. | Compositions and methods for treating neoplasias |
| WO2019067502A1 (en) | 2017-09-27 | 2019-04-04 | Alexion Pharmaceuticals, Inc. | METHODS FOR IMPROVING CARDIOVASCULAR FUNCTION AND TREATING CARDIOVASCULAR DISEASE USING RECOMBINANT ECTO-NUCLEOTIDE PYROPHOSPHATASE / PHOSPHODIESTERASE |
| US12012441B2 (en) | 2020-10-26 | 2024-06-18 | Neptune Biosciences Llc | Engineered human IL-21 cytokines and methods for using the same |
| WO2024040194A1 (en) | 2022-08-17 | 2024-02-22 | Capstan Therapeutics, Inc. | Conditioning for in vivo immune cell engineering |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6057128A (en) * | 1998-03-17 | 2000-05-02 | Genetics Institute, Inc. | MU-1, member of the cytokine receptor family |
| US7198789B2 (en) * | 1998-03-17 | 2007-04-03 | Genetics Institute, Llc | Methods and compositions for modulating interleukin-21 receptor activity |
| US7189400B2 (en) * | 1998-03-17 | 2007-03-13 | Genetics Institute, Llc | Methods of treatment with antagonists of MU-1 |
| US6576744B1 (en) * | 1998-09-23 | 2003-06-10 | Zymogenetics, Inc. | Cytokine receptor zalpha11 |
| DE60036930T2 (de) | 1999-03-09 | 2008-10-09 | Zymogenetics, Inc., Seattle | Humanes cytokin als ligand des zalpha rezeptors und dessen verwendungen |
| US6307024B1 (en) * | 1999-03-09 | 2001-10-23 | Zymogenetics, Inc. | Cytokine zalpha11 Ligand |
| AU5142300A (en) | 1999-05-18 | 2000-12-05 | Millennium Pharmaceuticals, Inc. | Il-9/il-2 receptor-like molecules and uses thereof |
| CA2420992C (en) * | 2000-04-05 | 2010-07-13 | Zymogenetics, Inc. | Soluble zalpha11 cytokine receptors |
| JP2004500845A (ja) | 2000-05-11 | 2004-01-15 | ジェネティクス インスティテュート，エルエルシー | サイトカインレセプターファミリーのメンバーであるｍｕ−１ |
| WO2003040313A2 (en) * | 2001-11-05 | 2003-05-15 | Zymogenetics, Inc | Il-21 antagonists |
| US20040016010A1 (en) * | 2002-04-17 | 2004-01-22 | Marion Kasaian | IL-21 receptor knockout animal and methods of use thereof |
| EP1531850B1 (en) * | 2002-06-07 | 2012-02-22 | ZymoGenetics, Inc. | Use of IL-21 and monoclonal antibody for treating solid cancers |
| JP4776228B2 (ja) * | 2002-07-15 | 2011-09-21 | ワイス・エルエルシー | Ｔヘルパー（ｔｈ）細胞の発生および機能を調節するための方法および組成物 |
| US7495085B2 (en) * | 2003-03-14 | 2009-02-24 | Wyeth | Antibodies against human or mouse IL-21 receptor |
| ZA200507235B (en) | 2003-03-21 | 2007-03-28 | Wyeth Corp | Treating immunological disorders using agonists of interleukin-21/interleukin-21 receptor |
| AU2004275871A1 (en) * | 2003-09-25 | 2005-04-07 | Zymogenetics, Inc. | Methods of treating autoimmune diseases using IL-21 |
| CA2566333A1 (en) * | 2004-05-19 | 2005-12-01 | Wyeth | Modulation of immunoglobulin production and atopic disorders |
| CN101052419A (zh) * | 2004-08-05 | 2007-10-10 | 惠氏公司 | 拮抗白介素－21受体活性 |
| KR20070057789A (ko) | 2004-08-05 | 2007-06-07 | 와이어쓰 | 인터루킨-21 수용체 활성의 상쇄 |
| GT200600148A (es) * | 2005-04-14 | 2006-11-22 | Metodos para el tratamiento y la prevencion de fibrosis | |
| WO2008081198A1 (en) | 2007-01-05 | 2008-07-10 | Imperial Innovations Ltd | Blood assays for predicting inflammatory responses |
-
2009
- 2009-05-22 AR ARP090101847A patent/AR071885A1/es not_active Application Discontinuation
- 2009-05-22 PE PE2009000719A patent/PE20100141A1/es not_active Application Discontinuation
- 2009-05-23 SA SA109300315A patent/SA109300315B1/ar unknown
- 2009-05-25 TW TW098117296A patent/TW201000129A/zh unknown
- 2009-05-25 CL CL2009001284A patent/CL2009001284A1/es unknown
- 2009-05-26 CA CA2724915A patent/CA2724915A1/en not_active Abandoned
- 2009-05-26 EP EP09751751A patent/EP2297199A1/en not_active Withdrawn
- 2009-05-26 MX MX2010012811A patent/MX2010012811A/es active IP Right Grant
- 2009-05-26 KR KR1020107028877A patent/KR20110040773A/ko not_active Withdrawn
- 2009-05-26 JP JP2011510744A patent/JP2011523849A/ja active Pending
- 2009-05-26 MY MYPI2010005509A patent/MY149448A/en unknown
- 2009-05-26 US US12/472,209 patent/US8163884B2/en not_active Expired - Fee Related
- 2009-05-26 WO PCT/US2009/045182 patent/WO2009143523A1/en not_active Ceased
- 2009-05-26 NZ NZ589330A patent/NZ589330A/xx not_active IP Right Cessation
- 2009-05-26 AU AU2009248809A patent/AU2009248809A1/en not_active Abandoned
- 2009-05-26 RU RU2010152690/10A patent/RU2010152690A/ru not_active Application Discontinuation
- 2009-05-26 CN CN200980128968XA patent/CN102105491A/zh active Pending
-
2010
- 2010-11-15 IL IL209328A patent/IL209328A0/en unknown
- 2010-11-19 ZA ZA2010/08335A patent/ZA201008335B/en unknown
- 2010-12-22 CO CO10160884A patent/CO6382184A2/es not_active Application Discontinuation
-
2012
- 2012-04-23 US US13/453,090 patent/US20120264919A1/en not_active Abandoned