JP2011523626A5 - - Google Patents
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- JP2011523626A5 JP2011523626A5 JP2011506488A JP2011506488A JP2011523626A5 JP 2011523626 A5 JP2011523626 A5 JP 2011523626A5 JP 2011506488 A JP2011506488 A JP 2011506488A JP 2011506488 A JP2011506488 A JP 2011506488A JP 2011523626 A5 JP2011523626 A5 JP 2011523626A5
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- Japan
- Prior art keywords
- chemotherapy
- composition
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- animal
- dietary composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 claims description 14
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 claims description 14
- HNDVDQJCIGZPNO-YFKPBYRVSA-N L-histidine Chemical compound OC(=O)[C@@H](N)CC1=CN=CN1 HNDVDQJCIGZPNO-YFKPBYRVSA-N 0.000 claims description 14
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 claims description 14
- AYFVYJQAPQTCCC-GBXIJSLDSA-N L-threonine Chemical compound C[C@@H](O)[C@H](N)C(O)=O AYFVYJQAPQTCCC-GBXIJSLDSA-N 0.000 claims description 14
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 claims description 13
- KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 claims description 13
- DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 claims description 12
- PWKSKIMOESPYIA-UHFFFAOYSA-N 2-acetamido-3-sulfanylpropanoic acid Chemical compound CC(=O)NC(CS)C(O)=O PWKSKIMOESPYIA-UHFFFAOYSA-N 0.000 claims description 7
- CKLJMWTZIZZHCS-UHFFFAOYSA-N D-OH-Asp Natural products OC(=O)C(N)CC(O)=O CKLJMWTZIZZHCS-UHFFFAOYSA-N 0.000 claims description 7
- QNAYBMKLOCPYGJ-UHFFFAOYSA-N D-alpha-Ala Natural products CC([NH3+])C([O-])=O QNAYBMKLOCPYGJ-UHFFFAOYSA-N 0.000 claims description 7
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims description 7
- QNAYBMKLOCPYGJ-UWTATZPHSA-N L-Alanine Natural products C[C@@H](N)C(O)=O QNAYBMKLOCPYGJ-UWTATZPHSA-N 0.000 claims description 7
- CKLJMWTZIZZHCS-UWTATZPHSA-N L-Aspartic acid Natural products OC(=O)[C@H](N)CC(O)=O CKLJMWTZIZZHCS-UWTATZPHSA-N 0.000 claims description 7
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 claims description 7
- QNAYBMKLOCPYGJ-REOHCLBHSA-N L-alanine Chemical compound C[C@H](N)C(O)=O QNAYBMKLOCPYGJ-REOHCLBHSA-N 0.000 claims description 7
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 claims description 7
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 claims description 7
- 229930182816 L-glutamine Natural products 0.000 claims description 7
- AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 claims description 7
- 229930182844 L-isoleucine Natural products 0.000 claims description 7
- 239000004395 L-leucine Substances 0.000 claims description 7
- 235000019454 L-leucine Nutrition 0.000 claims description 7
- 229930182821 L-proline Natural products 0.000 claims description 7
- 239000004473 Threonine Substances 0.000 claims description 7
- 229960003767 alanine Drugs 0.000 claims description 7
- 229960001230 asparagine Drugs 0.000 claims description 7
- 229960005261 aspartic acid Drugs 0.000 claims description 7
- 229960002989 glutamic acid Drugs 0.000 claims description 7
- 229960002743 glutamine Drugs 0.000 claims description 7
- 229960002885 histidine Drugs 0.000 claims description 7
- 229960000310 isoleucine Drugs 0.000 claims description 7
- 229960003136 leucine Drugs 0.000 claims description 7
- 229960002429 proline Drugs 0.000 claims description 7
- 229960001153 serine Drugs 0.000 claims description 7
- WPLOVIFNBMNBPD-ATHMIXSHSA-N subtilin Chemical compound CC1SCC(NC2=O)C(=O)NC(CC(N)=O)C(=O)NC(C(=O)NC(CCCCN)C(=O)NC(C(C)CC)C(=O)NC(=C)C(=O)NC(CCCCN)C(O)=O)CSC(C)C2NC(=O)C(CC(C)C)NC(=O)C1NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C1NC(=O)C(=C/C)/NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C2NC(=O)CNC(=O)C3CCCN3C(=O)C(NC(=O)C3NC(=O)C(CC(C)C)NC(=O)C(=C)NC(=O)C(CCC(O)=O)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(N)CC=4C5=CC=CC=C5NC=4)CSC3)C(C)SC2)C(C)C)C(C)SC1)CC1=CC=CC=C1 WPLOVIFNBMNBPD-ATHMIXSHSA-N 0.000 claims description 7
- 229960002898 threonine Drugs 0.000 claims description 7
- 229960004441 tyrosine Drugs 0.000 claims description 7
- 229960004295 valine Drugs 0.000 claims description 7
- QDGAVODICPCDMU-UHFFFAOYSA-N 2-amino-3-[3-[bis(2-chloroethyl)amino]phenyl]propanoic acid Chemical compound OC(=O)C(N)CC1=CC=CC(N(CCCl)CCCl)=C1 QDGAVODICPCDMU-UHFFFAOYSA-N 0.000 claims description 6
- ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 claims description 6
- 229930064664 L-arginine Natural products 0.000 claims description 6
- 235000014852 L-arginine Nutrition 0.000 claims description 6
- 235000007882 dietary composition Nutrition 0.000 claims description 6
- 229940024606 amino acid Drugs 0.000 claims description 5
- 235000001014 amino acid Nutrition 0.000 claims description 5
- 150000001413 amino acids Chemical class 0.000 claims description 5
- IFGCUJZIWBUILZ-UHFFFAOYSA-N sodium 2-[[2-[[hydroxy-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyphosphoryl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid Chemical compound [Na+].C=1NC2=CC=CC=C2C=1CC(C(O)=O)NC(=O)C(CC(C)C)NP(O)(=O)OC1OC(C)C(O)C(O)C1O IFGCUJZIWBUILZ-UHFFFAOYSA-N 0.000 claims description 5
- 235000012054 meals Nutrition 0.000 claims description 3
- 238000002512 chemotherapy Methods 0.000 claims 4
- 241001465754 Metazoa Species 0.000 claims 2
- FFEARJCKVFRZRR-SCSAIBSYSA-N D-methionine Chemical compound CSCC[C@@H](N)C(O)=O FFEARJCKVFRZRR-SCSAIBSYSA-N 0.000 claims 1
- 235000005911 diet Nutrition 0.000 claims 1
- 230000037213 diet Effects 0.000 claims 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 claims 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 description 5
- 229960004452 methionine Drugs 0.000 description 5
- FFEARJCKVFRZRR-UHFFFAOYSA-N L-Methionine Natural products CSCCC(N)C(O)=O FFEARJCKVFRZRR-UHFFFAOYSA-N 0.000 description 4
- 229930195722 L-methionine Natural products 0.000 description 4
- 235000018102 proteins Nutrition 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Natural products OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 description 2
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 description 2
- 235000009582 asparagine Nutrition 0.000 description 2
- 239000004475 Arginine Substances 0.000 description 1
- ODKSFYDXXFIFQN-BYPYZUCNSA-P L-argininium(2+) Chemical compound NC(=[NH2+])NCCC[C@H]([NH3+])C(O)=O ODKSFYDXXFIFQN-BYPYZUCNSA-P 0.000 description 1
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 description 1
- KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 description 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 description 1
- 235000009697 arginine Nutrition 0.000 description 1
- 229930182817 methionine Natural products 0.000 description 1
- 229960005190 phenylalanine Drugs 0.000 description 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 description 1
- 229960004799 tryptophan Drugs 0.000 description 1
- 239000004474 valine Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4768008P | 2008-04-24 | 2008-04-24 | |
| US61/047,680 | 2008-04-24 | ||
| PCT/US2009/041736 WO2009132320A2 (en) | 2008-04-24 | 2009-04-24 | Dietary compositions and methods for protection against chemotherapy, radiotherapy, oxidative stress, and aging |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015105690A Division JP2015186480A (ja) | 2008-04-24 | 2015-05-25 | 化学療法、放射線療法、酸化ストレス、および加齢を防御するための食事組成物ならびに方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011523626A JP2011523626A (ja) | 2011-08-18 |
| JP2011523626A5 true JP2011523626A5 (cg-RX-API-DMAC7.html) | 2015-07-16 |
Family
ID=41217444
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011506488A Pending JP2011523626A (ja) | 2008-04-24 | 2009-04-24 | 化学療法、放射線療法、酸化ストレス、および加齢を防御するための食事組成物ならびに方法 |
| JP2015105690A Pending JP2015186480A (ja) | 2008-04-24 | 2015-05-25 | 化学療法、放射線療法、酸化ストレス、および加齢を防御するための食事組成物ならびに方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015105690A Pending JP2015186480A (ja) | 2008-04-24 | 2015-05-25 | 化学療法、放射線療法、酸化ストレス、および加齢を防御するための食事組成物ならびに方法 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP2285218B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP2011523626A (cg-RX-API-DMAC7.html) |
| CA (2) | CA3045883C (cg-RX-API-DMAC7.html) |
| ES (1) | ES2800327T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2009132320A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6090836B2 (ja) * | 2011-02-17 | 2017-03-08 | Ｅａファーマ株式会社 | 化学療法剤の抗腫瘍活性増強剤 |
| JP5752980B2 (ja) * | 2011-04-04 | 2015-07-22 | 日本メジフィジックス株式会社 | 腎臓トランスポーターの輸送能を抑制するための組成物 |
| KR20150124962A (ko) * | 2013-02-12 | 2015-11-06 | 유니버시티 오브 써던 캘리포니아 | 화학 독성 및 연령 관련 질병으로부터 보호하기 위한 방법 및 규정식 |
| EP3113776B1 (en) * | 2014-03-06 | 2021-01-13 | University of Southern California | Use of short term starvation regimen in combination with kinase inhibitors to enhance traditional chemo-drug efficacy and feasibility and reverse side effects of kinases in normal cells and tissues |
| JP6551393B2 (ja) * | 2014-03-07 | 2019-07-31 | 味の素株式会社 | 虚弱予防剤 |
| US11000057B2 (en) * | 2015-05-06 | 2021-05-11 | University Of Southern California | Fasting mimicking and enhancing diet for treating hypertension and lipid disorders |
| EP3856167A1 (en) * | 2018-09-27 | 2021-08-04 | Société des Produits Nestlé S.A. | Use of histidine, glycine and other aminoacids for preventing insulin resistance and/or diabetes |
| EP4076458A1 (en) | 2019-12-19 | 2022-10-26 | Leibniz-lnstitut Für Altersforschung | Nad-precursors and dietary restriction for treating age-related medical conditions |
| JP7727286B2 (ja) * | 2020-09-23 | 2025-08-21 | アミノヴィタ エセ．エレ． | 癌の代謝療法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5535049A (en) * | 1978-09-04 | 1980-03-11 | Otsuka Pharmaceut Factory Inc | Amino acid transfusion for cancerous patient |
| US4574085A (en) * | 1981-05-15 | 1986-03-04 | Baxter Travenol Laboratories, Inc. | Method for using dialysis solution containing glycerol |
| FR2591893B1 (fr) * | 1985-12-19 | 1988-11-10 | Centre Nat Rech Scient | Compositions nutritionnelles carencees en methionine destinees a inhiber le developpement et la dissemination des tumeurs malignes chez les mammiferes |
| US4981687A (en) * | 1988-07-29 | 1991-01-01 | University Of Florida | Compositions and methods for achieving improved physiological response to exercise |
| JPH0368514A (ja) * | 1989-08-09 | 1991-03-25 | Morishita Pharmaceut Co Ltd | 癌用アミノ酸製剤 |
| FR2673812B1 (fr) * | 1991-03-13 | 1994-04-01 | Roussel Uclaf | Nouvelles compositions destinees a etre utilisees en dietetique et en therapeutique et renfermant une combinaison particuliere de glucides et leurs applications. |
| JPH04352720A (ja) * | 1991-05-30 | 1992-12-07 | Tanabe Seiyaku Co Ltd | 癌患者用アミノ酸製剤 |
| WO1993006834A1 (en) * | 1991-10-07 | 1993-04-15 | Otsuka Pharmaceutical Factory, Inc. | Enteral preparation for cancer therapy |
| JP3380287B2 (ja) * | 1992-04-07 | 2003-02-24 | 麒麟麦酒株式会社 | 血中アルコール濃度上昇阻害飲料 |
| US6338856B1 (en) * | 1998-02-27 | 2002-01-15 | Texas Tech University | Seaweed supplement diet for enhancing immune response in mammals and poultry |
| JPH11332514A (ja) * | 1998-05-22 | 1999-12-07 | Nof Corp | バランス栄養食品 |
| US7115297B2 (en) * | 2000-02-22 | 2006-10-03 | Suzanne Jaffe Stillman | Nutritionally fortified liquid composition with added value delivery systems/elements/additives |
| US7744930B2 (en) * | 2002-11-22 | 2010-06-29 | Shaklee Corporation | Compositions, methods and kits for enhancing weight loss while inhibiting loss of lean body mass |
| GB0416493D0 (en) * | 2004-07-23 | 2004-08-25 | Pitsiladis Yannis P | Hydrating composition |
| EP1731145A1 (en) * | 2005-05-25 | 2006-12-13 | Institut National De La Recherche Agronomique | Use of glycerol for improving cardiac function |
| WO2008123298A1 (ja) * | 2007-03-26 | 2008-10-16 | Hirofumi Matsui | 癌患者用輸液製剤 |
-
2009
- 2009-04-24 EP EP09734637.3A patent/EP2285218B1/en active Active
- 2009-04-24 WO PCT/US2009/041736 patent/WO2009132320A2/en not_active Ceased
- 2009-04-24 ES ES09734637T patent/ES2800327T3/es active Active
- 2009-04-24 JP JP2011506488A patent/JP2011523626A/ja active Pending
- 2009-04-24 CA CA3045883A patent/CA3045883C/en active Active
- 2009-04-24 CA CA2722365A patent/CA2722365C/en active Active
-
2015
- 2015-05-25 JP JP2015105690A patent/JP2015186480A/ja active Pending
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