JP2011522864A5 - - Google Patents
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- JP2011522864A5 JP2011522864A5 JP2011512988A JP2011512988A JP2011522864A5 JP 2011522864 A5 JP2011522864 A5 JP 2011522864A5 JP 2011512988 A JP2011512988 A JP 2011512988A JP 2011512988 A JP2011512988 A JP 2011512988A JP 2011522864 A5 JP2011522864 A5 JP 2011522864A5
- Authority
- JP
- Japan
- Prior art keywords
- use according
- seq
- medicament
- amino acid
- cac
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6116308P | 2008-06-13 | 2008-06-13 | |
| US61/061,163 | 2008-06-13 | ||
| PCT/EP2009/057263 WO2009150214A2 (en) | 2008-06-13 | 2009-06-12 | Unacylated ghrelin and analogs as therapeutic agents for vascular remodeling in diabetic patients and treatment of cardiovascular disease |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011522864A JP2011522864A (ja) | 2011-08-04 |
| JP2011522864A5 true JP2011522864A5 (https=) | 2012-07-05 |
| JP5481473B2 JP5481473B2 (ja) | 2014-04-23 |
Family
ID=41078180
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011512988A Expired - Fee Related JP5481473B2 (ja) | 2008-06-13 | 2009-06-12 | 糖尿病患者における血管リモデリングおよび心血管疾患治療のための治療薬としての非アシル化グレリンおよび類似体 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US8476408B2 (https=) |
| EP (1) | EP2310041B1 (https=) |
| JP (1) | JP5481473B2 (https=) |
| CN (1) | CN102065883A (https=) |
| AU (1) | AU2009256558B2 (https=) |
| CA (1) | CA2723270C (https=) |
| MX (1) | MX2010013677A (https=) |
| WO (1) | WO2009150214A2 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9651708B2 (en) * | 2011-04-21 | 2017-05-16 | Baker Hughes Incorporated | Method of mapping reservoir fluid movement using gravity sensors |
| PL2790721T3 (pl) | 2011-12-15 | 2019-05-31 | Millendo Therapeutics Sas | Fragmenty nieacylowanej greliny do zastosowania do leczenia zespołu pradera-williego |
| US10016458B2 (en) | 2012-04-16 | 2018-07-10 | Baystate Health, Inc. | p53 silenced endothelial progenitor cells for diabetes |
| WO2013190520A2 (en) | 2012-06-22 | 2013-12-27 | The General Hospital Corporation | Gh-releasing agents in the treatment of vascular stenosis and associated conditions |
| EP3010529B1 (en) | 2013-06-21 | 2020-05-06 | Millendo Therapeutics SAS | Use of unacylated ghrelin, fragments and analogs thereof as antioxidant |
| WO2015168207A1 (en) * | 2014-04-29 | 2015-11-05 | Mayo Foundation For Medical Education And Research | Butyrylcholinesterases having an enhanced ability to hydrolyze acyl ghrelin |
| WO2018053216A1 (en) | 2016-09-15 | 2018-03-22 | Mayo Foundation For Medical Education And Research | Methods and materials for using butyrylcholinesterases to treat cancer |
| GB201918853D0 (en) * | 2019-12-19 | 2020-02-05 | Lund Lars H | Methods of treatment |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5643872A (en) * | 1989-10-23 | 1997-07-01 | Smithkline Beecham Corporation | Cyclic anti-aggregatory peptides |
| US5747296A (en) * | 1992-05-11 | 1998-05-05 | Corvas International, Inc. | Method of detecting neutophil inhibitory factor mimics |
| WO1994013692A1 (en) * | 1992-12-10 | 1994-06-23 | Regents Of The University Of Minnesota | Polypeptides useful for treating inflammatory disorders |
| US5786332A (en) * | 1995-03-06 | 1998-07-28 | Trega Biosciences, Inc. | Cytokine restraining agents and methods of use in pathologies and conditions associated with altered cytokine levels |
| WO1995014787A1 (en) * | 1993-11-22 | 1995-06-01 | Centocor, Inc. | Peptide inhibitors of selecting binding |
| US5695761A (en) * | 1993-12-23 | 1997-12-09 | Rutgers University | Suppression of nitric oxide production by osteopontin |
| KR100360639B1 (ko) * | 1994-03-09 | 2003-01-30 | 코르텍, 인크. | N-치환글리신함유브라디키닌길항제펩티드 |
| US5958875A (en) * | 1996-03-29 | 1999-09-28 | The Regents Of The University Of California | Synthetic peptides derivatives with nerve growth factor-like neurotrophic activity |
| US6627729B1 (en) * | 1997-03-24 | 2003-09-30 | Zymogenetics, Inc. | TML peptides |
| US5932548A (en) * | 1998-06-03 | 1999-08-03 | Deghenghi; Romano | Lysine containing peptides for treatment of heart disease |
| WO2000023469A2 (en) * | 1998-10-16 | 2000-04-27 | Musc Foundation For Research Development | Fragments of insulin-like growth factor binding protein and insulin-like growth factor, and uses thereof |
| WO2001056592A1 (en) | 2000-02-01 | 2001-08-09 | Novo Nordisk A/S | Use of compounds for the regulation of food intake |
| EP1286697A2 (en) | 2000-05-17 | 2003-03-05 | Eli Lilly And Company | Method for selectively inhibiting ghrelin action |
| US6967237B2 (en) * | 2000-05-30 | 2005-11-22 | Merck & Co., Inc. | Ghrelin analogs |
| JP4493913B2 (ja) | 2001-01-31 | 2010-06-30 | 中外製薬株式会社 | 低栄養症状疾患治療剤 |
| US6872548B2 (en) * | 2001-01-31 | 2005-03-29 | Human Genome Sciences, Inc. | Scaffolded fusion polypeptides and compositions and methods for making the same |
| CA2470235C (en) | 2001-12-18 | 2012-02-07 | Theratechnologies Inc. | Pharmaceutical compositions comprising unacylated ghrelin and therapeutical uses thereof |
| US7666833B2 (en) * | 2001-12-18 | 2010-02-23 | Alizé Pharma SAS | Pharmaceutical compositions comprising unacylated ghrelin and therapeutical uses thereof |
| AU2002351593A1 (en) * | 2001-12-18 | 2003-06-30 | Theratechnologies Inc. | Pharmaceutical compositions comprising unacylated ghrelin and therapeutical uses thereof |
| AU2002364586A1 (en) * | 2001-12-21 | 2003-07-30 | Delta Biotechnology Limited | Albumin fusion proteins |
| EP1506786B1 (en) | 2002-05-21 | 2016-11-23 | Daiichi Sankyo Company, Limited | Medicinal compositions containing ghrelin |
| AU2004249904A1 (en) * | 2003-06-18 | 2004-12-29 | Direvo Biotech Ag | New biological entities and the pharmaceutical or diagnostic use thereof |
| US7517269B2 (en) | 2003-08-12 | 2009-04-14 | Parvia Corp. | Building element for constructing a modular substructure |
| US7825090B2 (en) | 2003-10-24 | 2010-11-02 | Alizé Pharma SAS | Use of ghrelin and unacylated ghrelin compositions for treating insulin resistance |
| US8076288B2 (en) * | 2004-02-11 | 2011-12-13 | Amylin Pharmaceuticals, Inc. | Hybrid polypeptides having glucose lowering activity |
| US20070237775A1 (en) * | 2004-07-14 | 2007-10-11 | Eli Lilly And Company | Anti-Ghrelin Antibodies |
| WO2006045319A2 (en) | 2004-10-27 | 2006-05-04 | Gastrotech Pharma A/S | Uses of growth hormone secretagogues in the treatment of individuals suffering from renal and/or liver failure |
| CA2587627A1 (en) * | 2004-11-15 | 2006-05-26 | Eli Lilly And Company | Desacyl ghrelin antibodies and therapeutic uses thereof |
| WO2007126792A2 (en) | 2006-03-28 | 2007-11-08 | Liat Mintz | Use of ghrelin splice variant for treating high cholesterol levels or high plasma glucose levels and releated diseases |
| EP2152297B1 (en) * | 2007-05-31 | 2015-04-29 | Alizé Pharma SAS | Unacylated ghrelin as therapeutic agent in the treatment of metabolic disorders |
| EP2067481A1 (en) | 2007-12-03 | 2009-06-10 | Charité-Universitätsmedizin Berlin | Therapeutic use of desacyl ghrelin |
-
2009
- 2009-06-11 US US12/482,882 patent/US8476408B2/en not_active Expired - Fee Related
- 2009-06-12 AU AU2009256558A patent/AU2009256558B2/en not_active Ceased
- 2009-06-12 MX MX2010013677A patent/MX2010013677A/es active IP Right Grant
- 2009-06-12 CA CA2723270A patent/CA2723270C/en not_active Expired - Fee Related
- 2009-06-12 JP JP2011512988A patent/JP5481473B2/ja not_active Expired - Fee Related
- 2009-06-12 WO PCT/EP2009/057263 patent/WO2009150214A2/en not_active Ceased
- 2009-06-12 US US12/996,244 patent/US20110160121A1/en not_active Abandoned
- 2009-06-12 EP EP09761776A patent/EP2310041B1/en active Active
- 2009-06-12 CN CN2009801222849A patent/CN102065883A/zh active Pending
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