JP2011520844A - 固相合成法により調製されたペプチドの精製 - Google Patents

固相合成法により調製されたペプチドの精製 Download PDF

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Publication number
JP2011520844A
JP2011520844A JP2011508936A JP2011508936A JP2011520844A JP 2011520844 A JP2011520844 A JP 2011520844A JP 2011508936 A JP2011508936 A JP 2011508936A JP 2011508936 A JP2011508936 A JP 2011508936A JP 2011520844 A JP2011520844 A JP 2011520844A
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JP
Japan
Prior art keywords
glp
peptide
propionyl
butanoyl
solid phase
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JP2011508936A
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English (en)
Japanese (ja)
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JP2011520844A5 (https=
Inventor
カミラ コルンベック,
トマス, ブッデ ハンセン,
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ノボ・ノルデイスク・エー/エス
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Publication of JP2011520844A publication Critical patent/JP2011520844A/ja
Publication of JP2011520844A5 publication Critical patent/JP2011520844A5/ja
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/605Glucagons
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/18Ion-exchange chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/20Partition-, reverse-phase or hydrophobic interaction chromatography

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
JP2011508936A 2008-05-15 2009-05-15 固相合成法により調製されたペプチドの精製 Withdrawn JP2011520844A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08156221.7 2008-05-15
EP08156221 2008-05-15
PCT/EP2009/055908 WO2009138488A1 (en) 2008-05-15 2009-05-15 Purification of peptides prepared by solid phase synthesis

Publications (2)

Publication Number Publication Date
JP2011520844A true JP2011520844A (ja) 2011-07-21
JP2011520844A5 JP2011520844A5 (https=) 2012-07-05

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ID=40843333

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011508936A Withdrawn JP2011520844A (ja) 2008-05-15 2009-05-15 固相合成法により調製されたペプチドの精製

Country Status (5)

Country Link
US (1) US20120149868A1 (https=)
EP (1) EP2280993A1 (https=)
JP (1) JP2011520844A (https=)
CN (1) CN102027005A (https=)
WO (1) WO2009138488A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1737889E (pt) 2004-10-19 2010-12-13 Lonza Ag Método para síntese de péptidos em fase sólida
SG191186A1 (en) 2010-12-15 2013-07-31 Baxter Int Eluate collection using conductivity gradient
US10450343B2 (en) 2013-03-21 2019-10-22 Sanofi-Aventis Deutschland Gmbh Synthesis of cyclic imide containing peptide products
CA2907454C (en) 2013-03-21 2021-05-04 Sanofi-Aventis Deutschland Gmbh Synthesis of hydantoin containing peptide products
WO2017136690A1 (en) * 2016-02-04 2017-08-10 University Of Washington Solid supports for use in solid-phase peptide synthesis, kits, and related methods
CN116390723B (zh) 2020-09-09 2024-12-31 社会利益网络公司 用于将生物素递送至线粒体的方法和组合物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69220888T2 (de) * 1991-11-05 1998-01-29 Perkin Elmer Corp Vorrichtung und Verfahren zur Herstellung von Biopolymeren
US6703362B1 (en) * 1997-05-15 2004-03-09 Cytogen Corporation Random peptides that bind to gastro-intestinal tract (GIT) transport receptors and related methods
EP1060192A2 (en) 1998-02-27 2000-12-20 Novo Nordisk A/S Glp-2 derivatives with helix-content exceeding 25 %, forming partially structured micellar-like aggregates
JP2003522099A (ja) 1998-02-27 2003-07-22 ノボ ノルディスク アクティーゼルスカブ 遅延作用プロファイルを有するglp−1のglp−1誘導体及びエキセンジン
WO1999058475A2 (en) * 1998-05-11 1999-11-18 Cambridge Combinatorial Limited Preparation of compounds using polymer supported reagents
US6902744B1 (en) 1999-01-14 2005-06-07 Amylin Pharmaceuticals, Inc. Exendin agonist formulations and methods of administration thereof
CZ20013018A3 (cs) 1999-03-17 2002-02-13 Novo Nordisk A/S Způsob pro acylování aminoskupiny peptidu nebo proteinu a sloučenina
SE0104462D0 (sv) * 2001-12-29 2001-12-29 Carlbiotech Ltd As Peptide purifcation (Peptidrening)
BRPI0413644A (pt) * 2003-08-21 2006-10-17 Novo Nordisk As métodos para separar as duas formas de um polipeptìdeo tendo uma única racemização de aminoácido, e para separar dois polipeptìdeos, produto de polipeptìdeo, e, composição farmacêutica
EP2181983A4 (en) * 2007-07-25 2013-01-02 Ajinomoto Kk METHOD FOR THE SELECTIVE REMOVAL OF A DIBENZOFULVENE DERIVATIVE

Also Published As

Publication number Publication date
US20120149868A1 (en) 2012-06-14
CN102027005A (zh) 2011-04-20
WO2009138488A1 (en) 2009-11-19
EP2280993A1 (en) 2011-02-09

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