JP2011517662A5 - - Google Patents
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- Publication number
- JP2011517662A5 JP2011517662A5 JP2010549807A JP2010549807A JP2011517662A5 JP 2011517662 A5 JP2011517662 A5 JP 2011517662A5 JP 2010549807 A JP2010549807 A JP 2010549807A JP 2010549807 A JP2010549807 A JP 2010549807A JP 2011517662 A5 JP2011517662 A5 JP 2011517662A5
- Authority
- JP
- Japan
- Prior art keywords
- mmp
- binding protein
- antibody
- binding
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3307508P | 2008-03-03 | 2008-03-03 | |
| US61/033,075 | 2008-03-03 | ||
| US5493808P | 2008-05-21 | 2008-05-21 | |
| US61/054,938 | 2008-05-21 | ||
| US13829708P | 2008-12-17 | 2008-12-17 | |
| US61/138,297 | 2008-12-17 | ||
| PCT/US2009/035840 WO2009111450A2 (en) | 2008-03-03 | 2009-03-03 | Metalloproteinase 9 binding proteins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011517662A JP2011517662A (ja) | 2011-06-16 |
| JP2011517662A5 true JP2011517662A5 (https=) | 2012-04-19 |
Family
ID=41056597
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010549807A Withdrawn JP2011517662A (ja) | 2008-03-03 | 2009-03-03 | メタロプロテアーゼ9結合タンパク質 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8008445B2 (https=) |
| EP (1) | EP2262529A4 (https=) |
| JP (1) | JP2011517662A (https=) |
| AU (1) | AU2009222048A1 (https=) |
| CA (1) | CA2717576A1 (https=) |
| WO (1) | WO2009111450A2 (https=) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2635588C (en) | 2005-12-30 | 2015-11-10 | Dyax Corp. | Metalloproteinase binding proteins |
| WO2009079581A1 (en) | 2007-12-17 | 2009-06-25 | Dyax Corp. | Evaluating mmp expression in patient stratification and other therapeutic, diagnostic and prognostic methods for cancer |
| AU2008338421A1 (en) | 2007-12-17 | 2009-06-25 | Dyax Corp. | Compositions and methods for treating osteolytic disorders comprising MMP-14 binding proteins |
| AU2009221916A1 (en) | 2008-03-03 | 2009-09-11 | Dyax Corp. | Metalloproteinase 9 and metalloproteinase 2 binding proteins |
| WO2009111450A2 (en) | 2008-03-03 | 2009-09-11 | Dyax Corp. | Metalloproteinase 9 binding proteins |
| WO2011028883A2 (en) * | 2009-09-03 | 2011-03-10 | Dyax Corp. | Metalloproteinase 9 and metalloproteinase 2 binding proteins |
| WO2011084749A1 (en) * | 2009-12-21 | 2011-07-14 | The Research Foundation Of State University Of New York | Compositions and methods for inhibiting mmp-9-mediated cell migration |
| US20130142734A1 (en) * | 2010-01-12 | 2013-06-06 | Ayelet David | Targeted delivery systems for diagnostic applications |
| US8697078B2 (en) * | 2010-01-27 | 2014-04-15 | Yeda Research And Development Co. Ltd. | Antibodies that inhibit metalloproteins |
| WO2011109738A1 (en) * | 2010-03-05 | 2011-09-09 | The Curators Of The University Of Missouri | Biomarkers of osteoarthritis |
| WO2011133555A2 (en) | 2010-04-20 | 2011-10-27 | The Research Foundation Of State University Of New York | Compositions and methods for inhibiting matrix metalloproteinase (mmp)-mediated cell migration |
| WO2012027127A2 (en) * | 2010-08-23 | 2012-03-01 | The Ohio State University Research Foundation | Elisa for haptoglobin-matrix metalloproteinase 9 complex as a diagnostic test for conditions including acute inflammation |
| CN105044349B (zh) | 2010-08-26 | 2018-04-06 | 弗·哈夫曼-拉罗切有限公司 | 生物标志物在评估从动脉高血压向心力衰竭的早期转变中的用途 |
| KR101930179B1 (ko) * | 2010-08-27 | 2018-12-17 | 길리아드 바이오로직스, 인크. | 매트릭스 메탈로프로테이나제 9에 대한 항체 |
| AU2015201367B2 (en) * | 2010-08-27 | 2016-12-15 | Gilead Sciences, Inc. | Antibodies to matrix metalloproteinase 9 |
| US10314909B2 (en) | 2011-10-21 | 2019-06-11 | Dyax Corp. | Combination therapy comprising an MMP-14 binding protein |
| NZ629178A (en) * | 2012-02-29 | 2016-09-30 | Gilead Biologics Inc | Antibodies to matrix metalloproteinase 9 |
| AU2012318302C1 (en) * | 2012-02-29 | 2017-06-15 | Gilead Biologics, Inc. | Antibodies to matrix metalloproteinase 9 |
| PL3489261T3 (pl) | 2012-08-24 | 2021-08-16 | The Regents Of The University Of California | Przeciwciała i szczepionki do stosowania w leczeniu nowotworów z ekspresją ROR1 i w hamowaniu przerzutu |
| JP6799201B2 (ja) | 2013-07-31 | 2020-12-16 | アヴァリン ファーマ インク. | エアロゾルチロシンキナーゼ阻害剤の化合物、及びその使用 |
| KR20150029457A (ko) * | 2013-09-10 | 2015-03-18 | 삼성전자주식회사 | 아넥신 a1에 결합하는 폴리펩타이드 및 그의 용도 |
| FR3015986A1 (fr) * | 2013-12-30 | 2015-07-03 | Lvmh Rech | Aptameres inhibiteurs de l'activite enzymatique de la proteine mmp-9 |
| EA201691414A1 (ru) * | 2014-02-27 | 2017-03-31 | Джилид Сайэнс, Инк. | Антитела к матриксной металлопротеиназе 9 и способы их применения |
| EP2985295A1 (en) * | 2014-08-13 | 2016-02-17 | Calypso Biotech SA | Antibodies specific for MMP9 |
| EP2985296A1 (en) * | 2014-08-13 | 2016-02-17 | Calypso Biotech SA | Antibodies specific for MMP9 |
| CR20180177A (es) | 2015-09-30 | 2018-06-22 | Janssen Biotech Inc | Anticuerpos agonistas que se unen específicamente a cd40 humana y método de uso |
| JP2016106147A (ja) * | 2016-03-14 | 2016-06-16 | ギリアード バイオロジックス, インコーポレイテッド | マトリックスメタロプロテイナーゼ9に対する抗体 |
| US20200306283A1 (en) | 2016-06-22 | 2020-10-01 | William Warren HARLESS | Cancer treatment and metastasis inhibition using an anti-cancer stem cell agent in combination with a neu1 sialidase inhibitor or a cytokine inhibitor after primary cancer treatment |
| IL299099B2 (en) | 2016-06-27 | 2025-07-01 | Univ California | Cancer treatment combinations |
| WO2018129090A1 (en) * | 2017-01-03 | 2018-07-12 | Trellis Bioscience, Llc | Native human antibodies for immune checkpoint modulation targets tim-3 and b7-h3 |
| US20230074615A1 (en) * | 2019-05-21 | 2023-03-09 | The Regents Of The University Of California | Mmp-9 antibodies and methods of use thereof |
| WO2022170126A2 (en) * | 2021-02-05 | 2022-08-11 | Adagio Therapeutics, Inc. | Compounds specific to coronavirus s protein and uses thereof |
| JP7474736B2 (ja) * | 2021-12-27 | 2024-04-25 | 花王株式会社 | 白斑の予防又は改善剤の評価又は選択方法 |
| CN120230208A (zh) * | 2024-08-07 | 2025-07-01 | 上海交通大学医学院附属第九人民医院 | 一组sh23同源簇全人源tsh受体阻断性单克隆抗体及其制备方法和应用 |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0736302A3 (en) * | 1995-03-23 | 1997-06-04 | Stichting Rega V Z W | Protease inhibitors, DNA construction for protease expression and a method for measuring proteases and / or protease inhibitors |
| GB9809764D0 (en) | 1998-05-07 | 1998-07-08 | Isis Innovation | MMP-9 Gene polymorphisms |
| CN1379685A (zh) * | 1999-07-13 | 2002-11-13 | 南加利福尼亚大学 | 用基于MMP-9和β1整联蛋白的拮抗剂抑制血管发生的新方法和组合物 |
| US7101975B1 (en) * | 1999-07-13 | 2006-09-05 | University Of Southern California | Method and composition for inhibition of angiogenesis using antagonists based on MMP-9 and β1 integrins |
| WO2001026671A1 (en) | 1999-10-12 | 2001-04-19 | Smithkline Beecham Corporation | Methods of treatment using dual matrix-metalloproteinase-2 and matrix metalloproteinase-9 inhibitors |
| US6573096B1 (en) * | 2000-04-01 | 2003-06-03 | The Research Foundation At State University Of New York | Compositions and methods for inhibition of cancer invasion and angiogenesis |
| EP1297112A2 (en) * | 2000-05-22 | 2003-04-02 | PHARMACIA & UPJOHN COMPANY | Novel matrix metalloproteinases |
| AR028606A1 (es) | 2000-05-24 | 2003-05-14 | Smithkline Beecham Corp | Nuevos inhibidores de mmp-2/mmp-9 |
| KR100919593B1 (ko) | 2000-06-29 | 2009-09-29 | 아보트 러보러터리즈 | 이중 특이성 항체 및 이의 제조 방법 및 이를 포함하는 조성물 |
| AU2001289930A1 (en) * | 2000-09-25 | 2002-04-08 | Rega Stichting Vzw | Method for the production of human antibodies, antibodies thus obtained and their use in therapy and diagnosis |
| US20070258987A1 (en) * | 2000-11-28 | 2007-11-08 | Seattle Genetics, Inc. | Recombinant Anti-Cd30 Antibodies and Uses Thereof |
| AU2002235692A1 (en) * | 2001-02-23 | 2002-09-04 | Biophage Inc. | Methods and compositions for preventing and treating neutrophil-mediated diseases |
| ATE458199T1 (de) * | 2001-05-04 | 2010-03-15 | Biosite Inc | Diagnostische marker der akuten koronaren syndrome und ihre verwendungen |
| AU2002352089A1 (en) * | 2001-11-23 | 2003-06-10 | Universite Catholique De Louvain | Medical use of antibodies directed against human matrix metalloproteinases or related tissue proteinases for the treatment of abnormal uterine bleeding and endometriosis |
| AU2003274059A1 (en) | 2002-10-23 | 2004-05-13 | F. Hoffmann-La Roche Ag | Combination of a trioxopyrimidine compound inhibitor and an anti-tumor agent, and uses thereof |
| ES2433440T3 (es) | 2003-04-04 | 2013-12-11 | Yeda Research And Development Co. Ltd. | Anticuerpos contra MMP2 o MMP9 y composiciones farmacéuticas que contienen los mismos útiles para inhibir la actividad de dichas metaloproteínas |
| US7435800B2 (en) * | 2003-05-23 | 2008-10-14 | Chi-Mei Medical Center | Antibodies to interleukin-20 and method for inhibiting interleukin-20 induced cell proliferation |
| US20050118632A1 (en) * | 2003-11-06 | 2005-06-02 | Jian Chen | Polynucleotides and polypeptides encoding a novel metalloprotease, Protease-40b |
| US20060002969A1 (en) * | 2004-01-27 | 2006-01-05 | University Of Washington | Methods for reducing the foreign body reaction |
| FI20040572A0 (fi) * | 2004-04-23 | 2004-04-23 | Ctt Cancer Targeting Tech Oy | Matriisi-metalloproteinaasin aktiviteetin inhibiittorit |
| CN100497324C (zh) | 2004-05-27 | 2009-06-10 | 武汉科艾硒医药科技发展有限公司 | 具有抗纤维化及抑制明胶酶活性的化合物及其应用 |
| WO2006036928A2 (en) | 2004-09-27 | 2006-04-06 | Wayne State University | Inhibitors of matrix metalloproteinases to treat neurological disorders |
| US20080254490A1 (en) | 2005-02-02 | 2008-10-16 | Ramkumar Menon | Salivary Protease Assays for Identifying Increased Risk of Preterm Delivery Induced by Premature Rupture of Fetal Membranes |
| DE102005015040A1 (de) | 2005-03-31 | 2006-10-05 | Sanofi-Aventis Deutschland Gmbh | Substituierte Tetrahydroisochinoline als MMP-Inhibitoren, Verfahren zu ihrer Herstellung und ihre Verwendung als Medikament |
| EP1931632A4 (en) * | 2005-08-18 | 2011-05-11 | Microbia Inc | USEFUL INDOOR CONNECTIONS |
| US8092819B2 (en) * | 2006-01-27 | 2012-01-10 | Cook Medical Technologies LLC. | Implantable medical device coated with a bioactive agent |
| WO2007149948A2 (en) | 2006-06-20 | 2007-12-27 | The Gov. Of The Usa As Represented By The Secretary Of The Department Of Health And Human Services | Compositions and methods for diagnosis and treatment of tumors |
| DK2185175T3 (da) * | 2007-08-15 | 2013-05-13 | Yeda Res & Dev | MMP-9-regulatorer og anvendelser deraf |
| KR20090034637A (ko) | 2007-10-04 | 2009-04-08 | 엘지전자 주식회사 | 차량용 거치대 |
| AU2008338421A1 (en) * | 2007-12-17 | 2009-06-25 | Dyax Corp. | Compositions and methods for treating osteolytic disorders comprising MMP-14 binding proteins |
| WO2009079581A1 (en) * | 2007-12-17 | 2009-06-25 | Dyax Corp. | Evaluating mmp expression in patient stratification and other therapeutic, diagnostic and prognostic methods for cancer |
| AU2009221916A1 (en) * | 2008-03-03 | 2009-09-11 | Dyax Corp. | Metalloproteinase 9 and metalloproteinase 2 binding proteins |
| WO2009111450A2 (en) | 2008-03-03 | 2009-09-11 | Dyax Corp. | Metalloproteinase 9 binding proteins |
| WO2010045388A2 (en) | 2008-10-14 | 2010-04-22 | Dyax Corp. | Use of mmp-9 and mmp-12 binding proteins for the treatment and prevention of systemic sclerosis |
| EP2350305A4 (en) | 2008-10-22 | 2013-03-06 | Dyax Corp | COMBINATION TREATMENTS WITH PROTEASE BINDING PROTEINS FOR INFLAMMATORY DISEASES |
| WO2011028883A2 (en) | 2009-09-03 | 2011-03-10 | Dyax Corp. | Metalloproteinase 9 and metalloproteinase 2 binding proteins |
-
2009
- 2009-03-03 WO PCT/US2009/035840 patent/WO2009111450A2/en not_active Ceased
- 2009-03-03 JP JP2010549807A patent/JP2011517662A/ja not_active Withdrawn
- 2009-03-03 EP EP09716600.3A patent/EP2262529A4/en not_active Withdrawn
- 2009-03-03 CA CA2717576A patent/CA2717576A1/en not_active Abandoned
- 2009-03-03 US US12/396,740 patent/US8008445B2/en active Active
- 2009-03-03 AU AU2009222048A patent/AU2009222048A1/en not_active Abandoned
-
2011
- 2011-07-26 US US13/191,411 patent/US8455205B2/en active Active
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