JP2011512362A5 - - Google Patents
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- Publication number
- JP2011512362A5 JP2011512362A5 JP2010546952A JP2010546952A JP2011512362A5 JP 2011512362 A5 JP2011512362 A5 JP 2011512362A5 JP 2010546952 A JP2010546952 A JP 2010546952A JP 2010546952 A JP2010546952 A JP 2010546952A JP 2011512362 A5 JP2011512362 A5 JP 2011512362A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- topical
- composition according
- item
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000000203 mixture Substances 0.000 claims description 54
- 230000000699 topical effect Effects 0.000 claims description 26
- 150000001875 compounds Chemical class 0.000 claims description 16
- 229940121363 anti-inflammatory agent Drugs 0.000 claims description 13
- 239000002260 anti-inflammatory agent Substances 0.000 claims description 13
- 125000003282 alkyl amino group Chemical group 0.000 claims description 4
- 125000000217 alkyl group Chemical group 0.000 claims description 4
- 229960003957 dexamethasone Drugs 0.000 claims description 4
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 claims description 4
- 125000004663 dialkyl amino group Chemical group 0.000 claims description 4
- QEFAQIPZVLVERP-UHFFFAOYSA-N nepafenac Chemical compound NC(=O)CC1=CC=CC(C(=O)C=2C=CC=CC=2)=C1N QEFAQIPZVLVERP-UHFFFAOYSA-N 0.000 claims description 4
- 229960001002 nepafenac Drugs 0.000 claims description 4
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 claims description 4
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 claims description 4
- 239000008194 pharmaceutical composition Substances 0.000 claims description 4
- 229960005205 prednisolone Drugs 0.000 claims description 4
- OIGNJSKKLXVSLS-VWUMJDOOSA-N prednisolone Chemical compound O=C1C=C[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 OIGNJSKKLXVSLS-VWUMJDOOSA-N 0.000 claims description 4
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims description 4
- 229960001487 rimexolone Drugs 0.000 claims description 4
- QTTRZHGPGKRAFB-OOKHYKNYSA-N rimexolone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CC)(C)[C@@]1(C)C[C@@H]2O QTTRZHGPGKRAFB-OOKHYKNYSA-N 0.000 claims description 4
- 239000002294 steroidal antiinflammatory agent Substances 0.000 claims description 4
- CFBUZOUXXHZCFB-OYOVHJISSA-N chembl511115 Chemical compound COC1=CC=C([C@@]2(CC[C@H](CC2)C(O)=O)C#N)C=C1OC1CCCC1 CFBUZOUXXHZCFB-OYOVHJISSA-N 0.000 claims description 3
- 229950001653 cilomilast Drugs 0.000 claims description 3
- 208000015181 infectious disease Diseases 0.000 claims description 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 2
- 239000003973 paint Substances 0.000 claims 2
- 238000000034 method Methods 0.000 description 9
- 208000014674 injury Diseases 0.000 description 3
- 230000008733 trauma Effects 0.000 description 3
- 208000001860 Eye Infections Diseases 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 206010061218 Inflammation Diseases 0.000 description 1
- 229940124307 fluoroquinolone Drugs 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2918008P | 2008-02-15 | 2008-02-15 | |
| PCT/US2009/034219 WO2009103053A1 (en) | 2008-02-15 | 2009-02-16 | Fluoroquinolone derivatives for ophthalmic applications |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011512362A JP2011512362A (ja) | 2011-04-21 |
| JP2011512362A5 true JP2011512362A5 (enExample) | 2013-02-21 |
Family
ID=40551911
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010546952A Withdrawn JP2011512362A (ja) | 2008-02-15 | 2009-02-16 | 眼科応用のためのフルオロキノロン誘導体 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US20090209574A1 (enExample) |
| EP (1) | EP2249836A1 (enExample) |
| JP (1) | JP2011512362A (enExample) |
| KR (1) | KR20100125318A (enExample) |
| CN (1) | CN101977604A (enExample) |
| AU (1) | AU2009214461A1 (enExample) |
| BR (1) | BRPI0907511A2 (enExample) |
| CA (1) | CA2714580A1 (enExample) |
| MX (1) | MX2010008927A (enExample) |
| WO (1) | WO2009103053A1 (enExample) |
| ZA (1) | ZA201005790B (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7220431B2 (en) | 2002-11-27 | 2007-05-22 | Regents Of The University Of Minnesota | Methods and compositions for applying pharmacologic agents to the ear |
| MX2014006056A (es) | 2011-12-06 | 2014-08-08 | Alcon Res Ltd | Composicion de gel de celulosa con una mejor estabilidad de la viscosidad. |
| US9504691B2 (en) * | 2012-12-06 | 2016-11-29 | Alcon Research, Ltd. | Finafloxacin suspension compositions |
| WO2014207769A1 (en) | 2013-06-27 | 2014-12-31 | Mylan Laboratories Ltd | Process for the preparation of nepafenac |
| WO2017151664A1 (en) * | 2016-02-29 | 2017-09-08 | Belmont University | Pharmaceutical compositions for fluoroquinolone drug delivery |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4880517A (en) * | 1984-10-01 | 1989-11-14 | Eltech Systems Corporation | Catalytic polymer electrode for cathodic protection and cathodic protection system comprising same |
| DE3906365A1 (de) * | 1988-07-15 | 1990-01-18 | Bayer Ag | 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe |
| US6440964B1 (en) * | 1998-09-30 | 2002-08-27 | Alcon Manufacturing, Ltd. | Compositions and methods for treating ophthalmic and otic infections |
| US6716830B2 (en) * | 1998-09-30 | 2004-04-06 | Alcon, Inc. | Ophthalmic antibiotic compositions containing moxifloxacin |
| US6740664B2 (en) * | 1998-09-30 | 2004-05-25 | Alcon, Inc. | Methods for treating otic and ophthalmic infections |
| US6509327B1 (en) * | 1998-09-30 | 2003-01-21 | Alcon Manufacturing, Ltd. | Compositions and methods for treating otic, ophthalmic and nasal infections |
-
2009
- 2009-02-16 WO PCT/US2009/034219 patent/WO2009103053A1/en not_active Ceased
- 2009-02-16 CN CN2009801096808A patent/CN101977604A/zh active Pending
- 2009-02-16 KR KR1020107020529A patent/KR20100125318A/ko not_active Withdrawn
- 2009-02-16 BR BRPI0907511-9A patent/BRPI0907511A2/pt not_active IP Right Cessation
- 2009-02-16 EP EP09710802A patent/EP2249836A1/en not_active Withdrawn
- 2009-02-16 MX MX2010008927A patent/MX2010008927A/es not_active Application Discontinuation
- 2009-02-16 CA CA2714580A patent/CA2714580A1/en not_active Abandoned
- 2009-02-16 JP JP2010546952A patent/JP2011512362A/ja not_active Withdrawn
- 2009-02-16 US US12/371,880 patent/US20090209574A1/en not_active Abandoned
- 2009-02-16 AU AU2009214461A patent/AU2009214461A1/en not_active Abandoned
-
2010
- 2010-08-13 ZA ZA2010/05790A patent/ZA201005790B/en unknown
-
2011
- 2011-03-08 US US13/043,118 patent/US20110160172A1/en not_active Abandoned
-
2012
- 2012-01-13 US US13/349,688 patent/US20120108557A1/en not_active Abandoned
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