JP2011511857A - 外科用の医療接着剤 - Google Patents

外科用の医療接着剤 Download PDF

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Publication number
JP2011511857A
JP2011511857A JP2010543413A JP2010543413A JP2011511857A JP 2011511857 A JP2011511857 A JP 2011511857A JP 2010543413 A JP2010543413 A JP 2010543413A JP 2010543413 A JP2010543413 A JP 2010543413A JP 2011511857 A JP2011511857 A JP 2011511857A
Authority
JP
Japan
Prior art keywords
tissue
adhesive system
component
adhesive
prepolymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2010543413A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011511857A5 (enExample
Inventor
ハイケ・ヘックロート
ブルクハルト・ケーラー
ゼバスティアン・デーア
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Covestro Deutschland AG
Original Assignee
Bayer MaterialScience AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer MaterialScience AG filed Critical Bayer MaterialScience AG
Publication of JP2011511857A publication Critical patent/JP2011511857A/ja
Publication of JP2011511857A5 publication Critical patent/JP2011511857A5/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40High-molecular-weight compounds
    • C08G18/48Polyethers
    • C08G18/4833Polyethers containing oxyethylene units
    • C08G18/4837Polyethers containing oxyethylene units and other oxyalkylene units
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/046Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/08Processes
    • C08G18/10Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08GMACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00Polymeric products of isocyanates or isothiocyanates
    • C08G18/06Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/72Polyisocyanates or polyisothiocyanates
    • C08G18/73Polyisocyanates or polyisothiocyanates acyclic
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09JADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
    • C09J175/00Adhesives based on polyureas or polyurethanes; Adhesives based on derivatives of such polymers
    • C09J175/04Polyurethanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Adhesives Or Adhesive Processes (AREA)
JP2010543413A 2008-01-24 2009-01-13 外科用の医療接着剤 Withdrawn JP2011511857A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08001290A EP2083025A1 (de) 2008-01-24 2008-01-24 Medizinische Klebstoffe für die Chirurgie
PCT/EP2009/000129 WO2009092524A1 (de) 2008-01-24 2009-01-13 Medizinische klebstoffe für die chirurgie

Publications (2)

Publication Number Publication Date
JP2011511857A true JP2011511857A (ja) 2011-04-14
JP2011511857A5 JP2011511857A5 (enExample) 2012-03-01

Family

ID=39577927

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010543413A Withdrawn JP2011511857A (ja) 2008-01-24 2009-01-13 外科用の医療接着剤

Country Status (11)

Country Link
US (1) US20090191145A1 (enExample)
EP (2) EP2083025A1 (enExample)
JP (1) JP2011511857A (enExample)
KR (1) KR20100117573A (enExample)
CN (1) CN101925625B (enExample)
AU (1) AU2009207883A1 (enExample)
BR (1) BRPI0906578A2 (enExample)
CA (1) CA2712648A1 (enExample)
ES (1) ES2396020T3 (enExample)
TW (1) TW200948839A (enExample)
WO (1) WO2009092524A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015509090A (ja) * 2012-01-09 2015-03-26 メディカル・アドヒーシブ・レボリューション・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングMedical Adhesive Revolution GmbH 修飾ベータ−アミノ酸エステル(アスパラギン酸エステル)硬化剤およびポリ尿素組織接着剤におけるその使用

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2011808A1 (de) * 2007-07-03 2009-01-07 Bayer MaterialScience AG Medizinische Klebstoffe für die Chirurgie
EP2095832A1 (de) * 2008-02-28 2009-09-02 Bayer MaterialScience AG Polyharnstoff-Systeme und deren Anwendung als postoperative Adhäsionsbarrieren, Filme und Verbundteile.
WO2010030544A1 (en) * 2008-09-12 2010-03-18 Dow Global Technologies Inc. Coating formulations and compositions based on polyamines, polyols and polyisocyanates, and processes of preparing and of using the same
DK2336212T3 (da) * 2009-12-12 2012-06-18 Bayer Materialscience Ag Klæbekombisystem til afdækning, lukning eller sammenklæbning af cellevæv
DE102010019504A1 (de) * 2010-05-06 2011-11-10 Bayer Materialscience Ag Polyisocyanatprepolymere und deren Verwendung
ES2527998T3 (es) * 2011-02-09 2015-02-03 Medical Adhesive Revolution Gmbh Adhesivo para tejidos basado en aspartatos modificados con nitrógeno
PL2673311T3 (pl) * 2011-02-09 2015-02-27 Bayer Materialscience Ag Kleje tkankowe na bazie trójfunkcjonalnych asparginianów
EP2543395A1 (de) * 2011-07-04 2013-01-09 Bayer MaterialScience AG Schichtaufbau zum Verschließen von Gewebeleckagen
DK2794798T3 (en) * 2011-12-20 2016-02-29 Medical Adhesive Revolution Gmbh HYDROXY AMINO POLYMER AND USE THEREOF IN POLY-UREA / POLYURETHAN-tissue adhesives
CN108570140A (zh) 2011-12-20 2018-09-25 阿德希西斯医疗有限公司 用于生物可降解组织粘合剂的异氰酸酯官能的预聚物
EP2695900B1 (en) * 2012-08-06 2019-03-20 Novachem Industriale S.r.l. Process for preparing a two-component polyurethane adhesive system
EP3456706A1 (de) 2017-09-19 2019-03-20 Covestro Deutschland AG Polyasparaginsäureester-zusammensetzungen und verfahren zur reinigung
WO2024132836A1 (en) * 2022-12-20 2024-06-27 Covestro Deutschland Ag Method of manufacturing a hydrogel useful for preventing post-surgical adhesions
EP4410322A1 (en) * 2023-02-02 2024-08-07 Covestro Deutschland AG Method of manufacturing a hydrogel useful for preventing post-surgical adhesions

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4477604A (en) * 1982-09-20 1984-10-16 Oechsle Iii Sixtus J Polyurethane compositions and their use as luting agents
US4804614A (en) * 1984-10-01 1989-02-14 The Aerospace Corporation Photoresist process of fabricating microelectronic circuits using water processable diazonium compound containing contrast enhancement layer
US4740534A (en) 1985-08-30 1988-04-26 Sanyo Chemical Industries, Ltd. Surgical adhesive
JPH04150866A (ja) 1990-10-15 1992-05-25 Nisshinbo Ind Inc 外科用接着剤
JP2928892B2 (ja) 1990-11-27 1999-08-03 三洋化成工業株式会社 外科用接着剤
US5156613A (en) 1991-02-13 1992-10-20 Interface Biomedical Laboratories Corp. Collagen welding rod material for use in tissue welding
US5243012A (en) 1992-06-10 1993-09-07 Miles Inc. Polyurea coating compositions having improved pot lives
US6017577A (en) 1995-02-01 2000-01-25 Schneider (Usa) Inc. Slippery, tenaciously adhering hydrophilic polyurethane hydrogel coatings, coated polymer substrate materials, and coated medical devices
EP1009291B8 (en) 1997-03-20 2006-01-11 Genzyme Corporation Biodegradable tissue retractor
US6355829B2 (en) 1999-09-02 2002-03-12 Bayer Corporation Aspartate-terminated urea/urethane prepolymers and their use in coating compositions
US6296607B1 (en) * 2000-10-20 2001-10-02 Praxis, Llc. In situ bulking device
US6724292B2 (en) * 2001-07-18 2004-04-20 Nec Schott Components Corporation Thermal fuse
US8501165B2 (en) 2001-12-12 2013-08-06 Promethean Surgical Devices Llc In situ bonds
US6747117B2 (en) * 2002-06-14 2004-06-08 Crompton Corporation Polyurethane/urea composition for coating cylindrical parts
DE10246708A1 (de) 2002-10-07 2004-04-15 Bayer Ag Zweikomponenten-Systeme für die Herstellung elastischer Beschichtungen
WO2005055958A2 (en) 2003-12-09 2005-06-23 Promethean Surgical Devices Llc Improved surgical adhesive and uses therefor
GB2415645A (en) * 2004-06-28 2006-01-04 L & I Maritime Ltd Cargo tank coating
US8044234B2 (en) * 2005-05-05 2011-10-25 Tyco Healthcare Group Lp Bioabsorbable surgical composition
EP1966311A4 (en) * 2005-12-08 2012-08-15 Tyco Healthcare SPRAY COMPOSITIONS WITH REDUCED VISCOSITY
EP2011808A1 (de) * 2007-07-03 2009-01-07 Bayer MaterialScience AG Medizinische Klebstoffe für die Chirurgie

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015509090A (ja) * 2012-01-09 2015-03-26 メディカル・アドヒーシブ・レボリューション・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングMedical Adhesive Revolution GmbH 修飾ベータ−アミノ酸エステル(アスパラギン酸エステル)硬化剤およびポリ尿素組織接着剤におけるその使用

Also Published As

Publication number Publication date
CN101925625B (zh) 2012-12-05
BRPI0906578A2 (pt) 2015-07-07
EP2245078A1 (de) 2010-11-03
CA2712648A1 (en) 2009-07-30
EP2245078B1 (de) 2012-10-24
EP2083025A1 (de) 2009-07-29
TW200948839A (en) 2009-12-01
KR20100117573A (ko) 2010-11-03
CN101925625A (zh) 2010-12-22
AU2009207883A1 (en) 2009-07-30
ES2396020T3 (es) 2013-02-18
WO2009092524A1 (de) 2009-07-30
US20090191145A1 (en) 2009-07-30

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