JP2011510085A - 緑内障治療におけるヒドラジン類 - Google Patents

緑内障治療におけるヒドラジン類 Download PDF

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Publication number
JP2011510085A
JP2011510085A JP2010544374A JP2010544374A JP2011510085A JP 2011510085 A JP2011510085 A JP 2011510085A JP 2010544374 A JP2010544374 A JP 2010544374A JP 2010544374 A JP2010544374 A JP 2010544374A JP 2011510085 A JP2011510085 A JP 2011510085A
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JP
Japan
Prior art keywords
phenyl
compound
hydroxy
another embodiment
following structure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
JP2010544374A
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English (en)
Japanese (ja)
Other versions
JP2011510085A5 (enExample
Inventor
ディヴィッド ダブリュー オールド
ダニー ティー ディン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allergan Inc
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of JP2011510085A publication Critical patent/JP2011510085A/ja
Publication of JP2011510085A5 publication Critical patent/JP2011510085A5/ja
Abandoned legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D333/40Thiophene-2-carboxylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2010544374A 2008-01-24 2009-01-15 緑内障治療におけるヒドラジン類 Abandoned JP2011510085A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2336508P 2008-01-24 2008-01-24
US12/353,290 US7956051B2 (en) 2008-01-24 2009-01-14 Therapeutic amides and related compounds
PCT/US2009/031081 WO2009094286A1 (en) 2008-01-24 2009-01-15 Hydrazines in glaucoma therapy

Publications (2)

Publication Number Publication Date
JP2011510085A true JP2011510085A (ja) 2011-03-31
JP2011510085A5 JP2011510085A5 (enExample) 2012-03-08

Family

ID=40899866

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010544374A Abandoned JP2011510085A (ja) 2008-01-24 2009-01-15 緑内障治療におけるヒドラジン類

Country Status (7)

Country Link
US (1) US7956051B2 (enExample)
EP (1) EP2247583A1 (enExample)
JP (1) JP2011510085A (enExample)
AU (1) AU2009206587A1 (enExample)
BR (1) BRPI0906661A2 (enExample)
CA (1) CA2712741A1 (enExample)
WO (1) WO2009094286A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014032735A1 (en) * 2012-09-03 2014-03-06 Grindeks Use of 3-(2,2,2-trimethylhydrazinium)-ethylpropionate or a pharmaceutically acceptable salt for treating high tension glaucoma

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4166452A (en) 1976-05-03 1979-09-04 Generales Constantine D J Jr Apparatus for testing human responses to stimuli
US4256108A (en) 1977-04-07 1981-03-17 Alza Corporation Microporous-semipermeable laminated osmotic system
US4265874A (en) 1980-04-25 1981-05-05 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
PT674516E (pt) 1992-12-16 2000-05-31 Agouron Pharma Compostos de 5-tiapirimidinona e 5-selenopirimidinona substituidos antiproliferativos
US5462968A (en) 1994-01-19 1995-10-31 Allergan, Inc. EP2 -receptor agonists as agents for lowering intraocular pressure
US5698598A (en) 1995-08-04 1997-12-16 Allergan EP2 -receptor agonists as agents for lowering intraocular pressure
US6090847A (en) 1997-11-21 2000-07-18 Allergan Sales, Inc. EP2 -receptor agonists as neuroprotective agents for the eye
US6437146B1 (en) 1998-09-25 2002-08-20 Fujisawa Pharmaceutical Co., Ltd. Oxazole compounds as prostaglandin e2 agonists or antagonists
BR0213911A (pt) 2001-11-05 2004-09-28 Allergan Inc Análogos de Èmega-cicloalquil 17-heteroaril prostaglandina e2 como agonistas do receptor ep2
US8148426B2 (en) 2004-11-19 2012-04-03 Synta Pharmaceuticals Corp. Bis(thio-hydrazide amides) for increasing Hsp70 expression
US7091231B2 (en) 2004-12-10 2006-08-15 Allergan, Inc. 12-Aryl prostaglandin analogs
WO2006121822A1 (en) * 2005-05-06 2006-11-16 Allergan, Inc. USE OF β-LACTAMS FOR THE TREATMENTOF IBD AND GLAUCOMA
FR2887879B1 (fr) 2005-07-01 2008-09-26 Trophos Sa Nouveaux composes chimiques et leurs utilisations comme medicament,particulierement dans le traitement des maladies neurodegeneratives
WO2007008942A2 (en) 2005-07-11 2007-01-18 Aerie Pharmaceuticals, Inc. Phenylamino-acetic acid [1-(pyridin-4-yl)-methylidene]-hydrazide derivatives and related compounds as modulators of g protein-coupled receptor kinases for the treatment of eye diseases
DE102006005179A1 (de) 2006-02-06 2007-08-09 Merck Patent Gmbh Aminoindazolderivate
JP2010500976A (ja) 2006-08-09 2010-01-14 アラーガン インコーポレイテッド 治療用アミド類および関連化合物

Also Published As

Publication number Publication date
WO2009094286A1 (en) 2009-07-30
US20090192151A1 (en) 2009-07-30
CA2712741A1 (en) 2009-07-30
BRPI0906661A2 (pt) 2015-07-14
US7956051B2 (en) 2011-06-07
EP2247583A1 (en) 2010-11-10
AU2009206587A1 (en) 2009-07-30

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