JP2011509296A - イオンチャネルリガンドとしてのアミド誘導体およびそれを使用する薬学的組成物および方法 - Google Patents

イオンチャネルリガンドとしてのアミド誘導体およびそれを使用する薬学的組成物および方法 Download PDF

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JP2011509296A
JP2011509296A JP2010542280A JP2010542280A JP2011509296A JP 2011509296 A JP2011509296 A JP 2011509296A JP 2010542280 A JP2010542280 A JP 2010542280A JP 2010542280 A JP2010542280 A JP 2010542280A JP 2011509296 A JP2011509296 A JP 2011509296A
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alkyl
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neuralgia
compound according
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JP2011509296A5 (OSRAM
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マシュー ダンクトン，
ドナフ ジョン ロジャー オマホニー，
マシュー コックス，
マリア デ ロス エンジェルス エスティアルテ−マルチネス，
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レノビス， インコーポレイテッド
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    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychology (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2010542280A 2008-01-09 2009-01-09 イオンチャネルリガンドとしてのアミド誘導体およびそれを使用する薬学的組成物および方法 Withdrawn JP2011509296A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1054208P 2008-01-09 2008-01-09
US12424008P 2008-04-14 2008-04-14
PCT/US2009/000150 WO2009089057A1 (en) 2008-01-09 2009-01-09 Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same

Publications (2)

Publication Number Publication Date
JP2011509296A true JP2011509296A (ja) 2011-03-24
JP2011509296A5 JP2011509296A5 (OSRAM) 2013-01-10

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JP2010542280A Withdrawn JP2011509296A (ja) 2008-01-09 2009-01-09 イオンチャネルリガンドとしてのアミド誘導体およびそれを使用する薬学的組成物および方法

Country Status (5)

Country Link
US (2) US8163901B2 (OSRAM)
EP (1) EP2240467B1 (OSRAM)
JP (1) JP2011509296A (OSRAM)
CA (1) CA2707441A1 (OSRAM)
WO (1) WO2009089057A1 (OSRAM)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2382197B1 (en) 2008-12-30 2016-10-05 Vertex Pharmaceuticals Incorporated Modulators of cystic fibrosis transmembrane conductance regulator
EP2447263A1 (en) 2010-09-27 2012-05-02 Bioprojet Benzazole derivatives as histamine H4 receptor ligands
LT3609868T (lt) 2017-03-13 2023-12-11 Raqualia Pharma Inc. Tetrahidrochinolino dariniai kaip p2x7 receptoriaus antagonistai
JP6994061B2 (ja) 2019-02-15 2022-01-14 ノバルティス アーゲー ４－（７－ヒドロキシ－２－イソプロピル－４－オキソ－４ｈ－キナゾリン－３－イル）－ベンゾニトリルの製剤
EP3923909A1 (en) 2019-02-15 2021-12-22 Novartis AG Methods for treating ocular surface pain

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1632477B1 (en) * 2003-06-12 2017-03-01 Astellas Pharma Inc. Benzamide derivative or salt thereof
FR2880625B1 (fr) 2005-01-07 2007-03-09 Sanofi Aventis Sa Derives de n-(heteroaryl)-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique
CA2645551C (en) * 2006-03-16 2016-06-28 Renovis, Inc. Bicycloheteroaryl compounds as p2x7 modulators and uses thereof
CA2651871A1 (en) * 2006-05-10 2007-11-22 Renovis, Inc. Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same
US8134004B2 (en) * 2006-07-11 2012-03-13 Pfizer Inc. Substituted N-bicyclicalkyl bicycliccarboxyamide compounds
WO2008090434A1 (en) * 2007-01-25 2008-07-31 Pfizer Japan Inc. Substituted n-bicyclicalkyl bicyclic carboxyamide compounds

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CA2707441A1 (en) 2009-07-16
EP2240467B1 (en) 2013-03-20
EP2240467A1 (en) 2010-10-20
US8163901B2 (en) 2012-04-24
US20130045973A1 (en) 2013-02-21
WO2009089057A1 (en) 2009-07-16
US20110028465A1 (en) 2011-02-03

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