JP2011505810A5 - - Google Patents
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- Publication number
- JP2011505810A5 JP2011505810A5 JP2010537235A JP2010537235A JP2011505810A5 JP 2011505810 A5 JP2011505810 A5 JP 2011505810A5 JP 2010537235 A JP2010537235 A JP 2010537235A JP 2010537235 A JP2010537235 A JP 2010537235A JP 2011505810 A5 JP2011505810 A5 JP 2011505810A5
- Authority
- JP
- Japan
- Prior art keywords
- human
- fragment
- nucleotide sequence
- antibody
- humanized anti
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 239000002773 nucleotide Substances 0.000 claims description 18
- 125000003729 nucleotide group Chemical group 0.000 claims description 18
- 239000012634 fragment Substances 0.000 claims description 11
- 125000003275 alpha amino acid group Chemical group 0.000 claims description 7
- 239000013604 expression vector Substances 0.000 claims description 7
- 230000027455 binding Effects 0.000 claims description 5
- 239000000427 antigen Substances 0.000 claims description 4
- 108091007433 antigens Proteins 0.000 claims description 4
- 102000036639 antigens Human genes 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 2
- 102100031573 Hematopoietic progenitor cell antigen CD34 Human genes 0.000 claims 9
- 101000777663 Homo sapiens Hematopoietic progenitor cell antigen CD34 Proteins 0.000 claims 9
- 102000006496 Immunoglobulin Heavy Chains Human genes 0.000 claims 5
- 108010019476 Immunoglobulin Heavy Chains Proteins 0.000 claims 5
- 102000013463 Immunoglobulin Light Chains Human genes 0.000 claims 5
- 108010065825 Immunoglobulin Light Chains Proteins 0.000 claims 5
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 4
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 4
- 210000004027 cell Anatomy 0.000 claims 3
- 150000001413 amino acids Chemical class 0.000 claims 2
- 229940127121 immunoconjugate Drugs 0.000 claims 2
- 230000001131 transforming effect Effects 0.000 claims 2
- 239000011324 bead Substances 0.000 claims 1
- 210000001185 bone marrow Anatomy 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 210000003958 hematopoietic stem cell Anatomy 0.000 claims 1
- 230000003525 myelopoietic effect Effects 0.000 claims 1
- 210000000130 stem cell Anatomy 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 description 5
- 108010076504 Protein Sorting Signals Proteins 0.000 description 2
- 108091008146 restriction endonucleases Proteins 0.000 description 2
- 239000013598 vector Substances 0.000 description 2
- 101100007328 Cocos nucifera COS-1 gene Proteins 0.000 description 1
- 238000000246 agarose gel electrophoresis Methods 0.000 description 1
- 125000000539 amino acid group Chemical group 0.000 description 1
- 238000000684 flow cytometry Methods 0.000 description 1
- 239000013612 plasmid Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200710094456 CN101245108B (zh) | 2007-12-13 | 2007-12-13 | 抗人cd34抗体、其制备方法及用途 |
| CN200810043016 | 2008-01-08 | ||
| PCT/CN2008/001963 WO2009079922A1 (en) | 2007-12-13 | 2008-12-03 | Humanized anti-cd34 monoclonal antibody, the preparation and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011505810A JP2011505810A (ja) | 2011-03-03 |
| JP2011505810A5 true JP2011505810A5 (enExample) | 2012-01-26 |
Family
ID=40800709
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010537235A Ceased JP2011505810A (ja) | 2007-12-13 | 2008-12-03 | ヒト化抗ヒトｃｄ３４抗体、その調製方法および使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20100311955A1 (enExample) |
| EP (1) | EP2233501B1 (enExample) |
| JP (1) | JP2011505810A (enExample) |
| BR (1) | BRPI0821211A2 (enExample) |
| CA (1) | CA2708407A1 (enExample) |
| WO (1) | WO2009079922A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2686418A4 (en) | 2011-03-17 | 2015-04-22 | Minerva Biotechnologies Corp | METHOD FOR THE PRODUCTION OF PLURIPOTENTAL STEM CELLS |
| US8785603B2 (en) | 2011-05-20 | 2014-07-22 | Siemens Healthcare Diagnostics Inc. | Antibodies to 25-hydroxyvitamin D2 and D3 and uses thereof |
| TWI443107B (zh) | 2011-12-29 | 2014-07-01 | Ind Tech Res Inst | 人源化之抗人類細胞表面抗原ｃｄ３４之單株抗體及其應用 |
| DK3105252T3 (da) | 2014-02-12 | 2019-10-14 | Michael Uhlin | Bispecifikke antistoffer til anvendelse ved stamcelletransplantation |
| US10604586B2 (en) * | 2016-05-09 | 2020-03-31 | Industrial Technology Research Institute | Humanized monoclonal antibody and uses thereof |
| CN109265547B (zh) * | 2018-07-23 | 2022-07-26 | 中国科学院微生物研究所 | 一种抗cd47抗体及其应用 |
| CN111879923A (zh) * | 2020-08-06 | 2020-11-03 | 深圳科隆生物新材料有限公司 | 一种可消除hama效应的试剂盒 |
| EP4463135A2 (en) | 2022-01-10 | 2024-11-20 | Sana Biotechnology, Inc. | Methods of ex vivo dosing and administration of lipid particles or viral vectors and related systems and uses |
| WO2024040195A1 (en) | 2022-08-17 | 2024-02-22 | Capstan Therapeutics, Inc. | Conditioning for in vivo immune cell engineering |
| WO2024081820A1 (en) | 2022-10-13 | 2024-04-18 | Sana Biotechnology, Inc. | Viral particles targeting hematopoietic stem cells |
| WO2024119157A1 (en) | 2022-12-02 | 2024-06-06 | Sana Biotechnology, Inc. | Lipid particles with cofusogens and methods of producing and using the same |
| AU2024274792A1 (en) | 2023-05-23 | 2025-10-23 | Sana Biotechnology, Inc. | Tandem fusogens and related lipid particles |
| WO2025006799A1 (en) | 2023-06-27 | 2025-01-02 | Capstan Therapeutics, Inc. | Extracorporeal and ex vivo engineering of select cell populations from peripheral blood |
| CN116970650B (zh) * | 2023-09-22 | 2023-12-08 | 深圳华大生命科学研究院 | 一种包膜蛋白组合、含其的靶向病毒载体及制备方法 |
| WO2025184529A1 (en) | 2024-03-01 | 2025-09-04 | Sana Biotechnology, Inc. | Viral particles with fusogen display and related compositions and methods |
| CN118501458B (zh) * | 2024-05-08 | 2025-09-30 | 广东省第二人民医院（广东省卫生应急医院） | 一种外周血细胞外囊泡表面多种免疫标志物联合检测的试剂盒及方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| JPH11332578A (ja) * | 1998-05-25 | 1999-12-07 | Asahi Chem Ind Co Ltd | 細胞の分離装置及び分離方法 |
| JPH11332594A (ja) * | 1998-05-26 | 1999-12-07 | Asahi Chem Ind Co Ltd | Ｃｄ４陽性細胞の分離装置および分離方法 |
| CN1307640A (zh) * | 1998-05-25 | 2001-08-08 | 旭化成株式会社 | 细胞分离装置和分离方法 |
| ATE382633T1 (de) * | 2000-05-23 | 2008-01-15 | Baxter Healthcare Sa | Reagenzien zur zellselektion und verfahren zur anwendung |
| US8728525B2 (en) * | 2004-05-12 | 2014-05-20 | Baxter International Inc. | Protein microspheres retaining pharmacokinetic and pharmacodynamic properties |
| CN101245108B (zh) * | 2007-12-13 | 2013-04-10 | 上海抗体药物国家工程研究中心有限公司 | 抗人cd34抗体、其制备方法及用途 |
-
2008
- 2008-12-03 CA CA2708407A patent/CA2708407A1/en not_active Abandoned
- 2008-12-03 EP EP08865354A patent/EP2233501B1/en not_active Not-in-force
- 2008-12-03 BR BRPI0821211-2A patent/BRPI0821211A2/pt not_active IP Right Cessation
- 2008-12-03 WO PCT/CN2008/001963 patent/WO2009079922A1/zh not_active Ceased
- 2008-12-03 US US12/746,990 patent/US20100311955A1/en not_active Abandoned
- 2008-12-03 JP JP2010537235A patent/JP2011505810A/ja not_active Ceased
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