JP2011504092A - 血管内皮増殖因子（ｖｅｇｆ）の血管新生誘発性アイソフォームに特異的な抗体 - Google Patents
血管内皮増殖因子（ｖｅｇｆ）の血管新生誘発性アイソフォームに特異的な抗体 Download PDFInfo
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| PCT/IL2008/001410 WO2009053987A1 (en) | 2007-10-25 | 2008-10-26 | Antibodies specific to pro-angiogenic isoforms of vascular endothelial growth factor (vegf) |
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| JP2011504092A true JP2011504092A (ja) | 2011-02-03 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014528693A (ja) * | 2011-06-15 | 2014-10-30 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 抗ヒトｅｐｏ受容体抗体及び使用方法 |
| WO2016194708A1 (ja) * | 2015-05-29 | 2016-12-08 | 国立大学法人名古屋大学 | 尿中ＶＥＧＦ－Ａ１６５ｂを指標とした腎機能の検査方法及び検査装置、腎機能の検査装置として機能させるためのプログラム及び記録媒体 |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7750124B2 (en) | 2006-09-29 | 2010-07-06 | Oncomed Pharmaceuticals, Inc. | Anti-human DLL4 antibodies and compositions |
| CN102459346B (zh) | 2009-04-27 | 2016-10-26 | 昂考梅德药品有限公司 | 制造异源多聚体分子的方法 |
| EP3485908B1 (en) | 2009-10-16 | 2021-08-18 | Mereo BioPharma 5, Inc. | Therapeutic combination and use of dll4 antagonist antibodies and anti-hypertensive agents |
| AU2010339723B2 (en) * | 2009-12-21 | 2014-11-06 | Mayo Foundation For Medical Education And Research | Early marker of proteinuria in patients treated with an anti-VEGF treatment |
| US8551479B2 (en) | 2010-09-10 | 2013-10-08 | Oncomed Pharmaceuticals, Inc. | Methods for treating melanoma |
| HRP20190044T1 (hr) | 2011-09-23 | 2019-02-22 | Oncomed Pharmaceuticals, Inc. | Agensi koji vežu vegf/dll4 i njihove uporabe |
| AU2013337811A1 (en) | 2012-10-31 | 2015-05-14 | Oncomed Pharmaceuticals, Inc. | Methods and monitoring of treatment with a DLL4 antagonist |
| US20150353617A1 (en) * | 2013-01-27 | 2015-12-10 | The Cleveland Clinic Foundation | Anti-angiogenic vegf-ax isoform |
| MX382902B (es) | 2014-10-31 | 2025-03-13 | Oncomed Pharm Inc | Inhibidor de la vía noth en combinación con un agente inmunoterapéutico para usarse en el tratamiento de cáncer. |
| WO2017053705A1 (en) | 2015-09-23 | 2017-03-30 | Oncomed Pharmaceuticals, Inc. | Methods and compositions for treatment of cancer |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001513111A (ja) * | 1997-03-03 | 2001-08-28 | ベス・イスラエル・デイーコネス・メデイカル・センター | 腫瘍付随血管（ｔｕｍｏｒ−ａｓｓｏｃｉａｔｅｄ ｂｌｏｏｄ ｖｅｓｓｅｌｓ）上の血管透過因子の複数のエピトープに結合する同時インビボイムノコンジュゲート |
| WO2005007198A2 (en) * | 2003-07-08 | 2005-01-27 | Attogen, Inc. | Design of disease specific agents for diagnostics and therapeutics based on the protein isoform of vegf, her-2, psa |
| JP2005502333A (ja) * | 2001-08-01 | 2005-01-27 | ユニバーシティ オブ ブリストル | 増殖因子イソ型 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US7667004B2 (en) | 2001-04-17 | 2010-02-23 | Abmaxis, Inc. | Humanized antibodies against vascular endothelial growth factor |
| US20060286636A1 (en) * | 2005-04-29 | 2006-12-21 | Shima David T | VEGF variants |
| US20080031815A1 (en) * | 2006-07-27 | 2008-02-07 | Xiaoyuan Chen | Pet imaging of vascular endothelial growth factor receptor (VEGFR), compositions for VEGF cancer imaging, and methods of VEGF cancer imaging |
| GB0704678D0 (en) | 2007-03-09 | 2007-04-18 | Univ Bristol | Pro- and anti-angiogenic treatments |
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2008
- 2008-10-26 AU AU2008315414A patent/AU2008315414A1/en not_active Abandoned
- 2008-10-26 JP JP2010530629A patent/JP2011504092A/ja active Pending
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- 2008-10-26 CA CA2703154A patent/CA2703154A1/en not_active Abandoned
- 2008-10-26 CN CN2008801226493A patent/CN101970486A/zh active Pending
- 2008-10-26 EP EP08842953A patent/EP2203480A1/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001513111A (ja) * | 1997-03-03 | 2001-08-28 | ベス・イスラエル・デイーコネス・メデイカル・センター | 腫瘍付随血管（ｔｕｍｏｒ−ａｓｓｏｃｉａｔｅｄ ｂｌｏｏｄ ｖｅｓｓｅｌｓ）上の血管透過因子の複数のエピトープに結合する同時インビボイムノコンジュゲート |
| JP2005502333A (ja) * | 2001-08-01 | 2005-01-27 | ユニバーシティ オブ ブリストル | 増殖因子イソ型 |
| WO2005007198A2 (en) * | 2003-07-08 | 2005-01-27 | Attogen, Inc. | Design of disease specific agents for diagnostics and therapeutics based on the protein isoform of vegf, her-2, psa |
Non-Patent Citations (4)
| Title |
|---|
| JPN6013037826; Ｃａｎｃｅｒ Ｒｅｓ．， ２００４， ６４（２１）， ｐｐ．７８２２-７８３５ * |
| JPN6013037827; Ｄｉａｂｅｔｏｌｏｇｉａ， ２００５， ４８（１１）， ｐｐ．２４２２-２４２７ * |
| JPN6013037828; Ｂｒ． Ｊ． Ｃａｎｃｅｒ， ２００７， ９７（２）， ｐｐ．２２３-２３０ （Ｅｐｕｂ ２００７ Ｊｕｎ ２６） * |
| JPN6013037829; Ｍｏｌ． Ｖｉｓ．， ２００６， １２， ｐｐ．６２６-６３２ * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014528693A (ja) * | 2011-06-15 | 2014-10-30 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | 抗ヒトｅｐｏ受容体抗体及び使用方法 |
| WO2016194708A1 (ja) * | 2015-05-29 | 2016-12-08 | 国立大学法人名古屋大学 | 尿中ＶＥＧＦ－Ａ１６５ｂを指標とした腎機能の検査方法及び検査装置、腎機能の検査装置として機能させるためのプログラム及び記録媒体 |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2703154A1 (en) | 2009-04-30 |
| AU2008315414A1 (en) | 2009-04-30 |
| CN101970486A (zh) | 2011-02-09 |
| US8592563B2 (en) | 2013-11-26 |
| EP2203480A1 (en) | 2010-07-07 |
| WO2009053987A1 (en) | 2009-04-30 |
| US20100272733A1 (en) | 2010-10-28 |
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