JP2011503072A - イオンチャネルのリガンドとしてのアミド誘導体ならびにそれを使用する薬学的組成物および方法 - Google Patents

イオンチャネルのリガンドとしてのアミド誘導体ならびにそれを使用する薬学的組成物および方法 Download PDF

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JP2011503072A
JP2011503072A JP2010533127A JP2010533127A JP2011503072A JP 2011503072 A JP2011503072 A JP 2011503072A JP 2010533127 A JP2010533127 A JP 2010533127A JP 2010533127 A JP2010533127 A JP 2010533127A JP 2011503072 A JP2011503072 A JP 2011503072A
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alkyl
methyl
compound according
substituted
ethyl
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JP2011503072A5 (fr
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マシュー コックス，
ドナフ ジョン ロジャー オマホニー，
マリア デ ロス エンジェルス エスティアルテ−マリネス，
忠史 川島
敏 長山
祐二 宍戸
博隆 田中
マシュー アレキサンダー ジェームス ダンクトン，
アンドリュー アントニー カラブレス，
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レノビス， インコーポレイテッド
ファイザー グローバル リサーチ アンド デベロップメント
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Publication of JP2011503072A publication Critical patent/JP2011503072A/ja
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JP2010533127A 2007-11-13 2008-11-13 イオンチャネルのリガンドとしてのアミド誘導体ならびにそれを使用する薬学的組成物および方法 Pending JP2011503072A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US283807P 2007-11-13 2007-11-13
PCT/US2008/012763 WO2009064449A1 (fr) 2007-11-13 2008-11-13 Dérivés amide à titre de ligands de canaux ioniques et compositions pharmaceutiques et procédés d'utilisation correspondants

Publications (2)

Publication Number Publication Date
JP2011503072A true JP2011503072A (ja) 2011-01-27
JP2011503072A5 JP2011503072A5 (fr) 2011-12-22

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JP2010533127A Pending JP2011503072A (ja) 2007-11-13 2008-11-13 イオンチャネルのリガンドとしてのアミド誘導体ならびにそれを使用する薬学的組成物および方法

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Country Link
US (1) US8153651B2 (fr)
EP (1) EP2215054B8 (fr)
JP (1) JP2011503072A (fr)
AT (1) ATE522500T1 (fr)
CA (1) CA2703220A1 (fr)
ES (1) ES2372655T3 (fr)
WO (1) WO2009064449A1 (fr)

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KR101645537B1 (ko) * 2008-11-11 2016-08-05 (주)아모레퍼시픽 바닐로이드 수용체 길항제로 작용하는 신규 화합물, 이의 이성질체 또는 이의 약제학적으로 허용 가능한 염 및 이를 포함하는 약학 조성물
WO2010056044A2 (fr) * 2008-11-11 2010-05-20 (주)아모레퍼시픽 Nouveau composé faisant fonction d'antagoniste du récepteur vanilloïde, isomère ou sel pharmaceutiquement acceptable dudit composé, et composition pharmaceutique le contenant
US8957254B2 (en) 2009-07-06 2015-02-17 Solvay Sa Process for chemical synthesis from an alkenone made from a halogenated precursor
EP3383868B1 (fr) * 2015-11-30 2022-10-05 Merck Sharp & Dohme LLC Sulfonamides d'aryle utilisés en tant qu'antagonistes de blt1
US10450309B2 (en) 2015-11-30 2019-10-22 Merch Sharp & Dohme Corp. Aryl sulfonamides as BLT1 antagonists
RU2624903C1 (ru) * 2016-11-02 2017-07-10 федеральное государственное автономное образовательное учреждение высшего образования "Казанский (Приволжский) федеральный университет" (ФГАОУ ВО КФУ) Производные ванилина с противоопухолевой активностью
US11046683B2 (en) 2016-12-15 2021-06-29 Ono Pharmaceutical Co., Ltd. Activator of TREK (TWIK RElated K+ channels) channels
LT3609868T (lt) 2017-03-13 2023-12-11 Raqualia Pharma Inc. Tetrahidrochinolino dariniai kaip p2x7 receptoriaus antagonistai
KR102622654B1 (ko) * 2021-02-22 2024-01-10 연세대학교 산학협력단 항염증용 조성물

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JP2004506713A (ja) * 2000-08-21 2004-03-04 パシフィック　コーポレーション 新規チオウレア誘導体およびこれを含有する薬学的組成物
WO2005003084A1 (fr) * 2003-07-02 2005-01-13 Grunenthal Gmbh Analogues de 4-(methyl sulfonyl amino)phenyle utilises en tant qu'antagonistes du recepteur vanilloide ayant une excellente activite analgesique, et compositions pharmaceutique les comprenant
WO2006093832A2 (fr) * 2005-02-28 2006-09-08 Renovis, Inc. Derives d'amide en tant que ligands de canal ionique, compositions pharmaceutiques et methodes d'utilisation associees
WO2006097817A1 (fr) * 2005-03-17 2006-09-21 Pfizer Japan Inc. Derives de n-(n-sulfonylaminomethyl)cyclopropanecarboxamide utilises pour traiter une douleur
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US8153651B2 (en) 2012-04-10
ATE522500T1 (de) 2011-09-15
CA2703220A1 (fr) 2009-05-22
WO2009064449A1 (fr) 2009-05-22
EP2215054B1 (fr) 2011-08-31
ES2372655T3 (es) 2012-01-25

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