JP2011503072A - イオンチャネルのリガンドとしてのアミド誘導体ならびにそれを使用する薬学的組成物および方法 - Google Patents

イオンチャネルのリガンドとしてのアミド誘導体ならびにそれを使用する薬学的組成物および方法 Download PDF

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JP2011503072A
JP2011503072A JP2010533127A JP2010533127A JP2011503072A JP 2011503072 A JP2011503072 A JP 2011503072A JP 2010533127 A JP2010533127 A JP 2010533127A JP 2010533127 A JP2010533127 A JP 2010533127A JP 2011503072 A JP2011503072 A JP 2011503072A
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alkyl
methyl
compound according
substituted
ethyl
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JP2011503072A5 (enExample
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マシュー コックス，
ドナフ ジョン ロジャー オマホニー，
マリア デ ロス エンジェルス エスティアルテ−マリネス，
忠史 川島
敏 長山
祐二 宍戸
博隆 田中
マシュー アレキサンダー ジェームス ダンクトン，
アンドリュー アントニー カラブレス，
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レノビス， インコーポレイテッド
ファイザー グローバル リサーチ アンド デベロップメント
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    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
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  • Psychiatry (AREA)
  • Obesity (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2010533127A 2007-11-13 2008-11-13 イオンチャネルのリガンドとしてのアミド誘導体ならびにそれを使用する薬学的組成物および方法 Pending JP2011503072A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US283807P 2007-11-13 2007-11-13
PCT/US2008/012763 WO2009064449A1 (en) 2007-11-13 2008-11-13 Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same

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JP2011503072A true JP2011503072A (ja) 2011-01-27
JP2011503072A5 JP2011503072A5 (enExample) 2011-12-22

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US (1) US8153651B2 (enExample)
EP (1) EP2215054B8 (enExample)
JP (1) JP2011503072A (enExample)
AT (1) ATE522500T1 (enExample)
CA (1) CA2703220A1 (enExample)
ES (1) ES2372655T3 (enExample)
WO (1) WO2009064449A1 (enExample)

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WO2010056044A2 (ko) * 2008-11-11 2010-05-20 (주)아모레퍼시픽 바닐로이드 수용체 길항제로 작용하는 신규 화합물, 이의 이성질체 또는 이의 약제학적으로 허용 가능한 염 및 이를 포함하는 약학 조성물
KR101645537B1 (ko) * 2008-11-11 2016-08-05 (주)아모레퍼시픽 바닐로이드 수용체 길항제로 작용하는 신규 화합물, 이의 이성질체 또는 이의 약제학적으로 허용 가능한 염 및 이를 포함하는 약학 조성물
US8957254B2 (en) 2009-07-06 2015-02-17 Solvay Sa Process for chemical synthesis from an alkenone made from a halogenated precursor
WO2017095725A1 (en) * 2015-11-30 2017-06-08 Merck Sharp & Dohme Corp. Aryl sulfonamides as blt1 antagonists
WO2017095724A1 (en) * 2015-11-30 2017-06-08 Merck Sharp & Dohme Corp. Aryl sulfonamides as blt1 antagonists
RU2624903C1 (ru) * 2016-11-02 2017-07-10 федеральное государственное автономное образовательное учреждение высшего образования "Казанский (Приволжский) федеральный университет" (ФГАОУ ВО КФУ) Производные ванилина с противоопухолевой активностью
EP3558992A4 (en) * 2016-12-15 2020-12-02 ONO Pharmaceutical Co., Ltd. TREK CHANNEL ACTIVATOR (K + CHANNELS ASSOCIATED WITH TWIK)
AU2018235561B2 (en) 2017-03-13 2020-06-18 Asahi Kasei Pharma Corporation Tetrahydroquinoline derivatives as P2X7 receptor antagonists
KR102622654B1 (ko) * 2021-02-22 2024-01-10 연세대학교 산학협력단 항염증용 조성물
US12099904B2 (en) 2021-03-10 2024-09-24 International Business Machines Corporation Uniform artificial intelligence model conversion

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WO2005003084A1 (en) * 2003-07-02 2005-01-13 Grunenthal Gmbh 4-(methyl sulfonyl amino) phenyl analogues as vanilloid antagonist showing excellent analgesic activity and the pharmaceutical compositions comprising the same
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WO2009064449A1 (en) 2009-05-22
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