JP2011502245A - 酵素検出のための電気化学的検定方法 - Google Patents

酵素検出のための電気化学的検定方法 Download PDF

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JP2011502245A
JP2011502245A JP2010530156A JP2010530156A JP2011502245A JP 2011502245 A JP2011502245 A JP 2011502245A JP 2010530156 A JP2010530156 A JP 2010530156A JP 2010530156 A JP2010530156 A JP 2010530156A JP 2011502245 A JP2011502245 A JP 2011502245A
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electrode
kinase
eam
substrate
enzyme
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JP2011502245A5 (cg-RX-API-DMAC7.html
Inventor
ベルタン,ポール,エー.
アーレンス,マイケル,ジェー.
ジョルガノポウロウ,ディミトラ
グレイ,ハリー,ビー.
ミード,トーマス,ジェー.
ウンダー,マルクス,フランツ
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オームクス コーポレーション
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28Electrolytic cell components
    • G01N27/30Electrodes, e.g. test electrodes; Half-cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001Enzyme electrodes
    • C12Q1/002Electrode membranes
    • C12Q1/003Functionalisation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00Metal working
    • Y10T29/49Method of mechanical manufacture
    • Y10T29/49002Electrical device making
    • Y10T29/49117Conductor or circuit manufacturing

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2010530156A 2007-10-17 2008-10-17 酵素検出のための電気化学的検定方法 Pending JP2011502245A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US98073307P 2007-10-17 2007-10-17
US8709408P 2008-08-07 2008-08-07
US8710208P 2008-08-07 2008-08-07
PCT/US2008/080363 WO2009052422A1 (en) 2007-10-17 2008-10-17 Electrochemical assay for the detection of enzymes

Publications (2)

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JP2011502245A true JP2011502245A (ja) 2011-01-20
JP2011502245A5 JP2011502245A5 (cg-RX-API-DMAC7.html) 2011-12-15

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JP2010530156A Pending JP2011502245A (ja) 2007-10-17 2008-10-17 酵素検出のための電気化学的検定方法
JP2010530160A Pending JP2011501161A (ja) 2007-10-17 2008-10-17 バイオセンサーに用いる新しい化学

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JP2010530160A Pending JP2011501161A (ja) 2007-10-17 2008-10-17 バイオセンサーに用いる新しい化学

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US (5) US8734631B2 (cg-RX-API-DMAC7.html)
EP (2) EP2212342A4 (cg-RX-API-DMAC7.html)
JP (2) JP2011502245A (cg-RX-API-DMAC7.html)
AU (2) AU2008312352A1 (cg-RX-API-DMAC7.html)
CA (2) CA2702977A1 (cg-RX-API-DMAC7.html)
WO (2) WO2009052422A1 (cg-RX-API-DMAC7.html)

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JP2014532720A (ja) * 2011-11-04 2014-12-08 オームクス コーポレイション バイオセンサーにおいて使用される新規化学
JP2015529809A (ja) * 2012-07-27 2015-10-08 オームクス コーポレイション 酵素及び他の標的分析物の存在及び活性の切断前検出後の単分子層の電気測定

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JP5792181B2 (ja) 2009-11-23 2015-10-07 ブリマン、ミカイル 炭素系電極の制御された電気化学的活性化
US9603940B2 (en) 2010-04-06 2017-03-28 Ihi Corporation Metal salen complex derivative and process for production thereof
WO2011146143A2 (en) 2010-05-21 2011-11-24 Ohmx Corporation Detection of cancer by assaying psa enzymatic activity
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FR2980989A1 (fr) * 2011-10-06 2013-04-12 Commissariat Energie Atomique Procede de fonctionnalisation d'un substrat solide autre qu'un substrat en or par des composes chimiques specifiques
EP2786134A1 (en) * 2011-12-02 2014-10-08 Koninklijke Philips N.V. Method and device for detecting ph value of a solution
EP2802669A1 (en) * 2012-01-09 2014-11-19 Ohmx Corporation Enzyme cascade methods for e-trace assay signal amplification
DE102012201843A1 (de) 2012-02-08 2013-08-08 Siemens Aktiengesellschaft Anordnung und Verfahren zur elektrischen Detektion von flüssigen Proben mit Lateral Flow Assays
EP3121288A1 (en) 2012-07-27 2017-01-25 Ohmx Corporation Electronic measurements of monolayers following homogeneous reactions of their components
GB2514825B (en) * 2013-06-06 2017-11-08 Bangor Univ Sensors
EP3047274A2 (en) 2013-09-20 2016-07-27 Ohmx Corporation Psa enzymatic activity: a new biomarker for assessing prostate cancer aggressiveness
CN106662583A (zh) 2014-04-29 2017-05-10 Ohmx公司 使用峰曲线的生物电子结合测定
WO2016025539A1 (en) * 2014-08-11 2016-02-18 Ohmx Corporation Enzyme triggered redox altering chemical elimination (-trace) assay with multiplexing capabilities
US10024817B2 (en) 2014-10-17 2018-07-17 Pelogenix, Llc Method for detecting proteases and active infection in biological fluids and tissues
US9373561B1 (en) 2014-12-18 2016-06-21 International Business Machines Corporation Integrated circuit barrierless microfluidic channel
WO2016100834A2 (en) * 2014-12-19 2016-06-23 Ohmx Corporation Competitive enzymatic assays
JP2018503830A (ja) * 2015-02-02 2018-02-08 ツー ポア ガイズ インコーポレイテッド バイオマーカー検出のための不安定なリンカー
US20170030907A1 (en) * 2015-06-26 2017-02-02 Uti Limited Partnership Tlr-4 based electrochemical biosensor
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US11793893B2 (en) 2016-10-03 2023-10-24 The Penn State Research Foundation Compounds comprising conductive oligomers, materials formed therefrom, and methods of making and using same
CN108760845B (zh) * 2018-05-21 2020-06-09 浙江工业大学 一种改性pb修饰电极及其制备方法
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CN111385495B (zh) * 2018-12-29 2022-02-11 天津大学青岛海洋技术研究院 一种用于补偿tof传感器中电荷转移不完全的方法
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014532720A (ja) * 2011-11-04 2014-12-08 オームクス コーポレイション バイオセンサーにおいて使用される新規化学
JP2015529809A (ja) * 2012-07-27 2015-10-08 オームクス コーポレイション 酵素及び他の標的分析物の存在及び活性の切断前検出後の単分子層の電気測定

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CA2702969A1 (en) 2009-04-23
US20140311922A1 (en) 2014-10-23
CA2702977A1 (en) 2009-04-23
JP2011501161A (ja) 2011-01-06
US20140342383A1 (en) 2014-11-20
AU2008311820A1 (en) 2009-04-23
WO2009052422A1 (en) 2009-04-23
EP2210268A1 (en) 2010-07-28
US20120156709A1 (en) 2012-06-21
WO2009052436A1 (en) 2009-04-23
EP2212342A1 (en) 2010-08-04
EP2212342A4 (en) 2010-11-17
EP2210268A4 (en) 2012-02-15
US20090253149A1 (en) 2009-10-08
US20150198552A9 (en) 2015-07-16
AU2008312352A1 (en) 2009-04-23
US8802390B2 (en) 2014-08-12
US8734631B2 (en) 2014-05-27
US20100003710A1 (en) 2010-01-07

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