JP2011500814A5 - - Google Patents
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- Publication number
- JP2011500814A5 JP2011500814A5 JP2010531058A JP2010531058A JP2011500814A5 JP 2011500814 A5 JP2011500814 A5 JP 2011500814A5 JP 2010531058 A JP2010531058 A JP 2010531058A JP 2010531058 A JP2010531058 A JP 2010531058A JP 2011500814 A5 JP2011500814 A5 JP 2011500814A5
- Authority
- JP
- Japan
- Prior art keywords
- mammal
- molecular entity
- cyclic peptide
- antibody
- analog
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000124008 Mammalia Species 0.000 claims 15
- 238000000034 method Methods 0.000 claims 13
- 108010069514 Cyclic Peptides Proteins 0.000 claims 9
- 102000001189 Cyclic Peptides Human genes 0.000 claims 9
- 230000002163 immunogen Effects 0.000 claims 8
- 239000000203 mixture Substances 0.000 claims 5
- 229920000642 polymer Polymers 0.000 claims 5
- 239000000126 substance Substances 0.000 claims 5
- 230000018612 quorum sensing Effects 0.000 claims 4
- 241000191967 Staphylococcus aureus Species 0.000 claims 3
- 125000000539 amino acid group Chemical group 0.000 claims 3
- 230000028993 immune response Effects 0.000 claims 3
- 208000015181 infectious disease Diseases 0.000 claims 3
- 125000005647 linker group Chemical group 0.000 claims 3
- 235000001014 amino acid Nutrition 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 230000002401 inhibitory effect Effects 0.000 claims 2
- 238000010255 intramuscular injection Methods 0.000 claims 2
- 239000007927 intramuscular injection Substances 0.000 claims 2
- 238000007912 intraperitoneal administration Methods 0.000 claims 2
- 238000001990 intravenous administration Methods 0.000 claims 2
- 235000018102 proteins Nutrition 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 238000007920 subcutaneous administration Methods 0.000 claims 2
- DJQYYYCQOZMCRC-UHFFFAOYSA-N 2-aminopropane-1,3-dithiol Chemical group SCC(N)CS DJQYYYCQOZMCRC-UHFFFAOYSA-N 0.000 claims 1
- 125000000729 N-terminal amino-acid group Chemical group 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 150000002678 macrocyclic compounds Chemical class 0.000 claims 1
- 239000002105 nanoparticle Substances 0.000 claims 1
- 230000003472 neutralizing effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98259307P | 2007-10-25 | 2007-10-25 | |
| US60/982,593 | 2007-10-25 | ||
| PCT/US2008/012151 WO2009055054A2 (en) | 2007-10-25 | 2008-10-24 | Antibody-mediated disruption of quorum sensing in bacteria |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014124700A Division JP6183910B2 (ja) | 2007-10-25 | 2014-06-17 | 抗体媒介による細菌のクオラムセンシングの破壊 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011500814A JP2011500814A (ja) | 2011-01-06 |
| JP2011500814A5 true JP2011500814A5 (cg-RX-API-DMAC10.html) | 2011-06-02 |
| JP5581490B2 JP5581490B2 (ja) | 2014-09-03 |
Family
ID=40580303
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010531058A Expired - Fee Related JP5581490B2 (ja) | 2007-10-25 | 2008-10-24 | 抗体媒介による細菌のクオラムセンシングの破壊 |
| JP2014124700A Expired - Fee Related JP6183910B2 (ja) | 2007-10-25 | 2014-06-17 | 抗体媒介による細菌のクオラムセンシングの破壊 |
| JP2017140405A Pending JP2018021021A (ja) | 2007-10-25 | 2017-07-19 | 抗体媒介による細菌のクオラムセンシングの破壊 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014124700A Expired - Fee Related JP6183910B2 (ja) | 2007-10-25 | 2014-06-17 | 抗体媒介による細菌のクオラムセンシングの破壊 |
| JP2017140405A Pending JP2018021021A (ja) | 2007-10-25 | 2017-07-19 | 抗体媒介による細菌のクオラムセンシングの破壊 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US9394371B2 (cg-RX-API-DMAC10.html) |
| EP (2) | EP2842565B1 (cg-RX-API-DMAC10.html) |
| JP (3) | JP5581490B2 (cg-RX-API-DMAC10.html) |
| KR (1) | KR101557173B1 (cg-RX-API-DMAC10.html) |
| CN (2) | CN104211775A (cg-RX-API-DMAC10.html) |
| AU (1) | AU2008317331B2 (cg-RX-API-DMAC10.html) |
| CA (2) | CA2975568A1 (cg-RX-API-DMAC10.html) |
| ES (1) | ES2603061T3 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2009055054A2 (cg-RX-API-DMAC10.html) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6445442B2 (ja) | 2012-10-26 | 2018-12-26 | ソレント・セラピューティクス・インコーポレイテッドＳｏｒｒｅｎｔｏ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． | Ａｉｐ２を結合する抗感染症結合タンパク質 |
| DE102013211850A1 (de) * | 2013-06-21 | 2014-12-24 | Gilupi Gmbh | Schnelltest zum Nachweisen von Erregermaterial, insbesondere zur Unterstützung der Diagnose einer Sepsis, sowie Kit und Vorrichtung zur Durchführung eines Sepsistests |
| AU2014298373B2 (en) * | 2013-08-01 | 2019-12-05 | Ludwig Institute For Cancer Research Ltd | Anti-GARP protein and uses thereof |
| JP2017509587A (ja) | 2013-12-27 | 2017-04-06 | ノーバス・インターナショナル・インコーポレイテッドＮｏｖｕｓ Ｉｎｔｅｒｎａｔｉｏｎａｌ，Ｉｎｃ． | エトキシル化界面活性剤 |
| JP6517156B2 (ja) * | 2014-01-29 | 2019-05-22 | Ｋｍバイオロジクス株式会社 | 抗トランスサイレチンヒト抗体 |
| CN106574258B (zh) | 2014-01-29 | 2021-03-30 | Km生物医药股份公司 | 抗-运甲状腺素蛋白人源化抗体 |
| EP3103808B1 (en) | 2014-02-07 | 2018-08-22 | Miyarisan Pharmaceutical Co., Ltd. | Peptide having activity of inhibiting production of toxin by bacterium belonging to genus clostridium |
| WO2017136400A1 (en) * | 2016-02-02 | 2017-08-10 | Stc. Unm | Vlp-based vaccines for targeting staphylococcus aureus secreted virulence factors |
| US12662513B2 (en) * | 2016-05-01 | 2026-06-23 | Wisconsin Alumni Research Foundation | Peptidic modulators of quorum sensing in Staphylococcus epidermidis |
| US10808010B2 (en) | 2016-08-11 | 2020-10-20 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Peptide inhibitors of phosphoglycerate mutase and methods of use |
| US10836810B2 (en) | 2017-02-17 | 2020-11-17 | Mapp Biopharmaceutical, Inc. | Monoclonal antibodies and cocktails for treatment of ebola infections |
| US10584306B2 (en) | 2017-08-11 | 2020-03-10 | Board Of Regents Of The University Of Oklahoma | Surfactant microemulsions |
| US20210177917A1 (en) * | 2017-08-31 | 2021-06-17 | The Regents Of The University Of California | Molecular bacteriotherapy to control skin enzymatic activity |
| JP7035170B2 (ja) | 2017-09-15 | 2022-03-14 | レンティジェン・テクノロジー・インコーポレイテッド | 抗ｃｄ１９免疫療法によりがんを処置するための組成物および方法 |
| US10774135B2 (en) | 2017-12-22 | 2020-09-15 | Sorrento Therapeutics, Inc. | Variant antibodies that bind AIP2 |
| JP7290146B2 (ja) | 2018-02-13 | 2023-06-13 | 住友化学株式会社 | 組成物および成形体 |
| EP4013372A4 (en) | 2019-08-13 | 2023-08-30 | McCord, Darlene E. | Non-activated, amorphous, ph neutral, two-part bedside-ready clay delivery system that treats pathogen infections in humans and animals |
| CN111573853B (zh) * | 2020-05-29 | 2020-11-20 | 南京大学 | 一种削减生物法处理废水毒性的方法 |
| WO2023076855A1 (en) | 2021-10-25 | 2023-05-04 | Mccord Darlene E | Coated medicinal clay compositions, pharmaceutical compositions, and delivery of cation sources and methods of use thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997044349A1 (en) * | 1996-05-22 | 1997-11-27 | New York University | BLOCKING EXPRESSION OF VIRULENCE FACTORS IN $i(S. AUREUS) |
| US6248329B1 (en) * | 1998-06-01 | 2001-06-19 | Ramaswamy Chandrashekar | Parasitic helminth cuticlin nucleic acid molecules and uses thereof |
| US6559176B1 (en) * | 2000-05-10 | 2003-05-06 | Princeton University | Compounds and methods for regulating bacterial growth and pathogenesis |
| US7786257B2 (en) * | 2000-12-18 | 2010-08-31 | University Of Kansas | Signal-1/signal-2 bifunctional peptide inhibitors |
| US6463632B2 (en) * | 2001-02-07 | 2002-10-15 | Hans Oetiker Ag Maschinen-Und Apparatefabrik | Guide arrangement for tightening tool emplacement in hose clamps provided with plastically deformable ears |
| CN1164612C (zh) * | 2001-09-11 | 2004-09-01 | 四川新泰克控股有限责任公司 | 人工组合的抗菌工程多肽及其制备方法 |
| JP4630663B2 (ja) * | 2002-08-13 | 2011-02-09 | ハプトゲン リミテッド | 抗ラクトンシグナル分子抗体または抗ラクトン由来シグナル分子抗体による感染性細菌症の治療のための方法 |
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2008
- 2008-10-24 AU AU2008317331A patent/AU2008317331B2/en not_active Ceased
- 2008-10-24 CA CA2975568A patent/CA2975568A1/en not_active Abandoned
- 2008-10-24 JP JP2010531058A patent/JP5581490B2/ja not_active Expired - Fee Related
- 2008-10-24 KR KR1020107011438A patent/KR101557173B1/ko not_active Expired - Fee Related
- 2008-10-24 US US12/734,273 patent/US9394371B2/en not_active Expired - Fee Related
- 2008-10-24 CA CA2703133A patent/CA2703133C/en active Active
- 2008-10-24 WO PCT/US2008/012151 patent/WO2009055054A2/en not_active Ceased
- 2008-10-24 EP EP14180831.1A patent/EP2842565B1/en active Active
- 2008-10-24 CN CN201410258364.XA patent/CN104211775A/zh active Pending
- 2008-10-24 EP EP08841487.5A patent/EP2211889B1/en active Active
- 2008-10-24 ES ES14180831.1T patent/ES2603061T3/es active Active
- 2008-10-24 CN CN200880113179.4A patent/CN101835484B/zh not_active Expired - Fee Related
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2014
- 2014-06-17 JP JP2014124700A patent/JP6183910B2/ja not_active Expired - Fee Related
-
2016
- 2016-07-14 US US15/210,450 patent/US20170043020A1/en not_active Abandoned
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2017
- 2017-07-19 JP JP2017140405A patent/JP2018021021A/ja active Pending