JP2011229613A - Biological light measuring device - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a biological light measuring device, capable of measuring a hemoglobin amount change signal with good reproducibility even when an operator is differed in clinical practice.SOLUTION: A control unit of the biological light measuring device displays a plurality of steps constituting an examination and an execution sequence of the plurality of steps on a display device, and executes the steps according to the execution sequence. The plurality of steps includes, for example, at least one of steps of explaining the examination, urging setting of a measuring probe and receiving setting of a measurement parameter from an operator; and a measuring step. The measuring step includes emitting a light to a subject, and detecting the light passed through the inside of the subject.

Description

  The present invention relates to a biological light measurement device that obtains information inside a living body by irradiating a living body with near infrared light and measuring light that has passed through or reflected inside the living body.

  The biological optical measurement device is a device that can easily measure blood circulation / hemodynamics and hemoglobin changes in a living body with low restraint on a subject and without causing harm to the living body. In the biological optical measurement device, many reports have been made on measuring the cerebral cortex activation state generated between the control task and the stimulation task. For example, Non-Patent Document 1 reports a change in cerebral cortical hemoglobin that occurs between “repeat of utterance without meaning (control task)” and “recollection utterance (stimulation task)”. In this report, “Aiueo” utterance is repeated as a control task, an initial is presented as a stimulus task, and word recall is performed based on this, and the control task time, the number of word recalls, and the stimulus time are reported. ing.

  Further, in Patent Document 1, a biological optical measurement device is clinically applied, and psychiatric disease determination (determination of depression, schizophrenia, bipolar disorder, etc.) information based on the characteristic amount of the hemoglobin amount change signal waveform. An apparatus for displaying is disclosed. By using this apparatus, it is possible to quantitatively determine a mental illness or the like from the feature amount of the hemoglobin amount change signal waveform.

International Publication Number WO2005 / 025421 Suto T el al: Multichannel near-infrared spectroscopy in depression and schizophrenia: cognitive brain activation study.Biol Psychiatry 55: 501-511 2004.

  In order to use a biological light measurement device for clinical examination of a subject and perform disease determination etc., it is possible to measure a hemoglobin amount change signal with good reproducibility without depending on changes in the operator, date and place. Is desired.

  For that purpose, it is important for the operator to carefully explain in advance in advance what kind of inspection task is to be performed to the subject in the actual inspection. In this explanation, it is necessary to prevent the explanation from being different even if the operators are different, and it is recommended to use video or the like. Further, regarding the installation of the measurement probe, it is necessary to appropriately install it at the designated measurement site. In addition, as a stimulation task, if you use the same initial letter as in the previous test, when you perform “recollection utterance” in which the initial letter is presented to the subject and the word recalled from the initial letter is uttered The difficulty level may be low and proper inspection may not be possible.

  An object of the present invention is to provide a living body light measurement apparatus capable of measuring a hemoglobin amount change signal with high reproducibility even when operators are different clinically.

  In order to achieve the above object, according to the present invention, the following biological light measuring device is provided. That is, the biological light measurement device of the present invention includes a light irradiation unit that irradiates light to a subject, a detection unit that detects light that has passed through the inside of the subject, and a control unit, The process and the execution order of the processes are shown to the operator, and only the next process or the repetition of the current process according to the execution order is accepted from the operator and the received process is executed. It is characterized by.

  For example, the control unit causes a display device to display an image indicating a plurality of steps and the execution order, and the image highlights selectable steps.

  The plurality of steps may be configured to include at least one or more of an inspection explanation step, a step for prompting installation of a measurement probe, a step for receiving measurement parameter settings from an operator, and a measurement step. At this time, the measurement step is a step of irradiating the subject with light by detecting the light irradiation unit and the detection unit, and detecting the light passing through the inside of the subject.

  For example, as the examination explanation process, the control unit reproduces an image stored in advance in the storage device and causes the display device to display the image.

  For example, as a step of prompting the installation of the measurement probe, the control unit displays an image indicating the attachment position of the measurement probe on the display device, and then images the subject to which the measurement probe is attached by the imaging device. It is configured to be stored in a storage device. In this case, the control unit can detect the positional deviation amount of the measurement probe by comparing the image captured by the imaging device with an image stored in advance in the storage device.

  For example, as a step of receiving the setting of the measurement parameter from the operator, the control unit is configured to receive an input of a task to be executed by the subject from the operator and store the task in a storage device. At this time, when the past problem executed by the subject is stored in the storage device, the control unit compares the past problem with the currently input problem, and when the problem is the same, It is possible to perform a display prompting the operator to change to a different task.

  For example, the control unit can be configured to prompt the subject to execute the task received in the step of receiving the setting of the measurement parameter from the operator by at least one of an image and a sound and perform the measurement step during the task execution. is there.

  According to the present invention, the plurality of steps constituting the inspection and the execution order of the plurality of steps are shown to the operator, and the selection is accepted from the operator only for the next process or the repetition of the current process according to the execution order. Even if the operator differs clinically, the hemoglobin amount change signal can be measured with good reproducibility.

The block diagram which shows the whole structure of the biological light measuring device of embodiment of this invention. Explanatory drawing which shows the external appearance which is test | inspecting a subject with the biological light measuring device of embodiment. The flowchart which shows operation | movement of the test | inspection guidance and implementation part 181 of the biological light measuring device of embodiment. Explanatory drawing which shows an example of the navigation screen 41 which the test | inspection guidance and implementation part 181 of embodiment displays. Explanatory drawing which shows the example of the image which the test | inspection guidance and implementation part 181 of embodiment made the camera part 5 image. Explanatory drawing which shows an example of the screen 61 displayed on the 1st display part in order for the test | inspection guidance and implementation part 181 of embodiment to receive the input of a measurement parameter.

  Hereinafter, a biological light measurement device according to an embodiment of the present invention will be described.

  FIG. 1 shows an apparatus configuration of the biological light measurement device according to the present embodiment, and FIG. 2 shows an outline of an appearance in a state where a test (measurement) of a subject is performed by the biological light measurement device. As shown in FIGS. 1 and 2, the biological light measurement apparatus includes an optical module unit 2, an arithmetic processing unit 3, a speaker 4, a camera unit 5, two display units 6 and 7, and a magnetic sensor 8.

  The optical module unit 2 mixes a light source 13 that emits a plurality of types of optical signals obtained by frequency-modulating light of two predetermined wavelengths and a two-wavelength optical signal emitted from the light source 13 and propagates the mixture to the subject 1. A plurality of irradiating optical fibers 11, a detection optical fiber 12 that propagates a two-wavelength optical signal that has passed through the measurement site of the subject 1, and a two-wavelength optical signal that the detection optical fiber 12 propagates. A detector 14 for detection and a detector 15 for detecting the output signal of the detector 14 for each modulation frequency are included. Near infrared light (for example, 695 nm and 830 nm) is used as the two wavelengths of light emitted from the light source 13. The exit end of the irradiation optical fiber 11 and the entrance end of the detection optical fiber 12 (hereinafter also referred to as the probe 50) are alternately held in a predetermined arrangement by the holder 16. The holder 16 is fixed to the subject 1 and brings the tip of the probe 50 into contact with the subject 1. The passage region of the light inside the subject 1 located between the emission end of the irradiation optical fiber 11 and the incidence end of the detection optical fiber 12 becomes a measurement site.

  The arithmetic processing unit 3 includes an A / D converter 17 that converts an output signal of the detector 15 into a digital signal, an arithmetic unit 18 that includes a CPU, a memory, and the like, an input unit such as a keyboard and a mouse, and a hard disk drive And the like storage unit 19. The computing unit 18 guides an operator to perform an inspection according to a predetermined procedure, and controls each part of the optical module unit 2 to perform an inspection guidance / execution unit 181 that performs an inspection with high reproducibility. A hemoglobin amount change signal is obtained by processing the signal obtained by the examination, and a predetermined calculation process is performed based on the hemoglobin amount change signal 182 for generating a predetermined image, and the disease of the subject 1 And a disease determination unit 183 that generates an image for displaying the determination result. The examination guidance / execution unit 181, the hemoglobin amount calculation unit 182, and the disease determination unit 183 are realized by the CPU executing programs stored in advance in the memory in the calculator 18.

  The first display unit 6 is a display device for displaying an image (for example, an image for prompting an operation, an image for accepting an operation, an image of a measurement result and a determination result) for an operator. The second display unit 7 is a display device for displaying an image (for example, an explanation video of an inspection method) on the subject 1. In the vicinity of the second display unit 7, a camera unit 5 for photographing the appearance of the subject 1 on which the probe 50 and the holder 16 are installed is arranged. The speaker 4 is used to play a sound for notifying the subject of the subject and a sound of an instructional video for the inspection method to the subject 1, and is arranged in a range where the sound reaches the subject 1. The speaker 4 may be built in the second display device 7, or a headphone can be used instead of the speaker 4.

  The magnetic sensor 8 is a device for detecting the position of the probe 50 attached to the subject 1. As shown in FIG. 1, the magnetic sensor 8 controls the magnetic source 81, the reference magnetic sensor 82, the variable magnetic sensor 83, and controls the position and calculates the position and angle of the magnetic sensor 82 with respect to the magnetic source 81. Part 84. The position measurement unit 84 is connected to the calculation processing unit 3, and the position information measured by the position measurement unit 84 is passed to the calculator 18.

  The magnetic source 81 includes a magnetic field generating coil, and generates a three-axis orthogonal magnetic field in a three-dimensional space in which the subject 1 is disposed. For example, the magnetic source 81 is fixed in a space in the vicinity where the biological light measurement device is installed. The reference magnetic sensor 82 is installed in the magnetic field space generated by the magnetic source 81, the reference magnetic sensor 82 becomes the reference position, and the magnetic field detected by the reference magnetic sensor 82 becomes the reference magnetic field. When performing biological light measurement, it is attached to a predetermined position on the head of the subject 1, for example, a specific position behind the ear. The variable magnetic sensor 83 is a pen-type sensor called a stylus pen, and includes a registration button (not shown) for registering the spatial position of the pen tip. The operator can register the position of the pen tip by freely moving the variable magnetic sensor 83 in the magnetic field generated by the magnetic source 81 and pressing the registration button.

  The position measurement unit 84 receives signals from the reference magnetic sensor 82 and the variable magnetic sensor 83 in real time at a predetermined sampling interval, and the variable magnetic sensor 83 detects the direction and angle of the magnetic field detected by the reference magnetic sensor 82. Using the direction and angle of the magnetic field, the coordinates of the pen tip position of the variable magnetic sensor 83 with the position of the reference magnetic sensor 82 as the origin are calculated. The position measuring unit 84 reads the spatial position of the variable magnetic sensor 83 when the registration button of the variable magnetic sensor 83 is pressed, and calculates the read coordinate value of the variable magnetic sensor 83 as the calculator 18. The computing unit 18 registers this in the built-in memory or the storage unit 19.

  Next, the operation of the inspection guidance / execution unit 181 will be described. The inspection guide / execution unit 181 controls each unit as in the flowchart shown in FIG. 3 to guide the operator and perform the inspection of the subject.

  First, the examination guidance / execution unit 181 prompts the operator to input subject (patient) information and displays a screen for receiving the input on the first display unit 6. An operator who is prompted to input by looking at the screen of the first display unit 6 operates the keyboard or mouse of the input unit 20 to input patient information (for example, name, age, sex, patient management number, etc.). If so, the inspection guidance / execution unit 181 accepts this. The examination guidance / execution unit 181 searches whether or not past measurement data corresponding to the received patient information is stored in the storage unit 19, and determines that it is a new measurement when there is no past measurement data. If it is determined in step 102 that there is past measurement data, it is determined that remeasurement is performed, and the process proceeds to step 110.

  If it is a new measurement, in step 102, the examination guidance / execution unit 181 displays the navigation screen 41 of the examination procedure shown in FIG. The navigation screen 41 in FIG. 4 displays a series of processes (processes) from the start to the end of the inspection to the operator, and the operator selects buttons 42 to 47 for each process in the screen 41. This is a screen for accepting the start of the process. The screen 41 is always displayed on a part of the screen area of the first display unit 6 until the inspection is completed. The buttons 42 to 47 on the navigation screen 41 are accepted by the examination guidance / implementation unit 181 even if the operator selects a button on the lower level until the button process on the upper level is completed. Absent. Accordingly, it is possible to perform control so that the upper process (for example, the inspection instruction video reproduction process) is omitted and the lower process (for example, installation of the measurement probe) cannot be performed. Of the buttons 42 to 47, the selectable button is preferably highlighted (for example, the display brightness of the button is increased or blinked) so that the operator can intuitively know that the button can be selected.

  In step 102, the examination guidance / execution unit 181 makes it possible to select the button 42 for the examination explanation video reproduction process. If the operator selects the examination explanation video process button 42 on the screen 41 in FIG. 4, the examination guidance / execution unit 181 reproduces the video stored in the storage unit 19 in advance and displays the reproduced image as the second image. While being displayed on the display unit 7, reproduced sound is played from the speaker 4. Here, as an example of the test, let the subject perform predetermined “repeat of utterance without meaning (control task)” and “recollection utterance (stimulation task)”, and change signal of hemoglobin when each task is performed The test which calculates | requires and calculates the difference of the hemoglobin amount change signal at the time of a stimulation task and the hemoglobin amount change signal at the time of a control task is implemented. In the video, after the test repeats a meaningless utterance (for example, Aiueo) several times, as a word-recall utterance, a hiragana character (for example, “a”) that is audibly spoken from the speaker is heard by ear, and the hiragana 1 The content is edited to carefully explain to the subject that he / she speaks as many words as possible starting with letters, and then to practice it.

  The inspection guidance / execution unit 181 makes it possible to accept selection by the operator of the button 43 in the measurement probe installation process on the screen 41 when the reproduction of the video is completed. For example, the operator highlights the button 43 to notify the operator. At this time, it is also possible to accept selection of the button 42 for the inspection instruction video reproduction process again. As a result, when the subject cannot understand the examination contents with one reproduction, the reproduction can be reproduced again and explained.

  If the operator has selected the button 43 for the measurement probe installation process, the inspection guidance / execution unit 181 proceeds to step 103 to display a first image indicating the installation position of the measurement probe 50 to the operator by illustration or the like. It is displayed on the display unit 6. In addition, a button (installation completion button) for notifying the inspection guidance / execution unit 181 that the installation of the measurement probe has been completed by the operator is also displayed on the first display unit 6. The operator can check the position where the measurement probe 50 should be installed by looking at the screen of the first display unit 6, attach the holder 16 to the subject 1, and install the measurement probe 50 at a predetermined position. . After the installation is completed, the operator selects an installation completion button displayed on the first display unit 6.

  If the installation completion button is selected, the inspection guide / execution unit 181 proceeds to step 104, and the camera unit 5 displays an external image of the holder 16 and the measurement probe 50 installed on the subject 1 as shown in FIG. Take an image. Furthermore, the installation position of the measurement probe 50 is measured and registered by the magnetic sensor 8 by the operation of the operator.

  First, the inspection guidance / execution unit 181 controls the camera unit 5 to capture an appearance image in which the holder 16 and the measurement probe 50 are installed on the subject 1. In the example of FIG. 5, the measurement probe 50 is installed at the installation positions 51 to 54. The installation position 51 of the measurement probe 50 is, for example, a position corresponding to the top of the subject 1. The measurement probe installation position 52 is, for example, a position corresponding to a nadion (nasal root) of the subject 1. The measurement probe installation position 53 is, for example, a position corresponding to the upper end portion of the left ear of the subject 1 (position closest to the left ear). The measurement probe installation position 52 is, for example, a position corresponding to the upper end portion of the right ear of the subject 1 (position closest to the right ear). Note that the examination guidance / execution unit 181 can also display a display on the second display unit 7 that prompts the subject 1 to look straight at the camera 16 and stand still at the time of imaging. The captured image is stored in the storage unit 19 in association with the subject (patient) information.

  Subsequently, the inspection guidance / implementation unit 181 displays a display on the first display unit 6 that prompts the operator to measure and register the installation position of the measurement probe 50 with the magnetic sensor 8. The operator attaches the reference magnetic sensor 82 to a predetermined position on the head of the subject 1, for example, a specific position behind the ear. Next, the operator holds a pen-type variable magnetic sensor 82 called a stylus pen in his / her hand, contacts the measurement probe installation positions 51 to 54 in order, and repeatedly presses the registration button, thereby repeating the measurement probe. The positions of the installation positions 51 to 54 are stored in the storage unit 19 via the calculator 18.

  Whether the captured image stored in the storage unit 19 and the position coordinates of the installation positions 51 to 54 of the measurement probe 50 are installed at the same position as at the time of new measurement when remeasurement is performed in steps 110 to 115 described later. Used to check if.

  After the imaging is completed, the examination guidance / execution unit 181 enables the selection by the operator of the button 44 in the measurement parameter setting process on the screen 41 in FIG. 4. If the operator selects the measurement parameter setting step button 44, the inspection guidance / execution unit 181 proceeds to step 105, displays a screen for accepting measurement parameter setting input from the operator, and is displayed by the operator. Accept input. As a measurement parameter, a single hiragana character of a task used in a word recall utterance, a speech time setting for a word recall utterance, or the like is accepted.

  When the setting of the measurement parameter 44 is completed, the examination guidance / execution unit 181 enables the selection of the measurement start button 45 by the operator. If the operator selects the measurement start button 45, the inspection guidance / execution unit 181 proceeds to step 106, emits a light signal of two wavelengths that is frequency-modulated from the light source 13, and detects the test from the irradiation optical fiber 11. The optical module unit 2 is controlled to irradiate the person 1. The optical signal that has passed through the measurement site and propagated through the detection optical fiber 12 is detected and detected by the detector 14 and the detector 15, converted by the A / D converter 17, and taken into the computing unit 18. The captured signal is stored in the memory of the arithmetic unit 18. The inspection guidance / execution unit 180 controls these operations.

  The examination guidance / execution unit 180 proceeds to step 107 to display a screen prompting the subject 1 to perform the control task and the stimulation task on the second display device 7, and at the time of the word recall utterance that is the stimulation task. Then, the speaker 4 is controlled to play the sound of one character of the hiragana character.

  A predetermined measurement time during which the subject 1 is executing the task, emission of light from the light source 13, detection and detection by the detector 14 and the detector 15, and signal acquisition by the arithmetic unit 18 are continued.

  When the predetermined measurement time has elapsed and all the set tasks have been completed, the inspection guidance / implementation unit 180 can accept the selection by the operator of the measurement end button 46. If the operator selects the measurement end button 46, the process proceeds to step 108, and the measurement data taken into the memory of the computing unit 18 and the measurement parameter set in step 105 (one letter of the hiragana character of the task, speech time) Etc.) is stored in the storage unit 19 in association with the subject (patient) information.

  The inspection guidance / execution unit 180 can accept selection by the operator of the result display button 47, and if the operator selects it, the process proceeds to step 109, and by performing a predetermined calculation based on the measurement result, A predetermined calculation result (a change in hemoglobin for each measurement site or a disease determination based on a difference between the control task and the stimulation task of the hemoglobin change) is obtained and displayed on the first display unit 6 in a predetermined display mode. Let The calculated inspection result is stored in the storage unit 19.

  When calculating the hemoglobin amount, the examination guidance / execution unit 181 activates the hemoglobin amount calculation unit 182 to execute calculation processing. Since the calculation processing of the hemoglobin amount based on the measurement data is a widely known calculation method, description thereof is omitted here. Also, in the case of performing disease determination based on the difference between the hemoglobin amount change signals at the time of the control task and the stimulation task, the test guidance / execution unit 181 activates the disease determination unit 183 and measures measurement data such as hemoglobin amount change data. Then, the calculation process is executed and the determination is performed. The calculation processing of the disease determination is to obtain one or more feature amounts of the difference signal of the hemoglobin amount change signal at the time of the control task and the stimulus task, and to compare the obtained feature amount with the feature amount previously obtained for each disease Thus, it is a process for determining the disease of the subject 1, and for example, a known technique described in Patent Document 1 or the like can be used.

  On the other hand, if the past measurement data corresponding to the received patient information is stored in the storage unit 19 in step 101 and it is determined that remeasurement is performed, the examination guidance / execution unit 180 proceeds to step 110. The appearance image of the subject 1 on which the holder 16 and the measurement probe 50 are installed, the position coordinates of the probe 50, and the step 105 of the previous inspection, which are taken as shown in FIG. 5 in the step 104 of the previous inspection (previous measurement). The measurement parameters set in step (1) are read from the storage unit 19 and temporarily stored in the memory in the calculator 18.

  Thereafter, the inspection guidance / execution unit 181 makes it possible to select the button 42 for the inspection explanation video reproduction process. If the operator selects the examination explanation video process button 42 on the screen 41 in FIG. 4, the process proceeds to step 111, and the video is reproduced in the same manner as in step 102. When the reproduction of the video is completed, the selection by the operator of the button 43 in the measurement probe installation process on the screen 41 can be accepted. If the button 43 is selected, the process proceeds to step 112 and the measurement probe is sent to the operator. The first display unit 6 displays an image for instructing the installation position of FIG.

  If the operator completes the installation of the measurement probe on the subject 1 and selects the installation completion button, the inspection guidance / execution unit 181 proceeds to step 113, and the holder 16 and the measurement probe 50 are moved as in step 104. The appearance image of the subject 1 installed is captured by the camera unit 5 as shown in FIG. Further, a display prompting the operator to measure and register the installation position of the measurement probe 50 with the magnetic sensor 8 is displayed on the first display unit 6, and the operator positions the installation positions 51 to 54 of the measurement probe 50. Register coordinates.

  The first display unit 6 displays an image showing the image captured at the previous inspection read at step 110 and the image captured at the current inspection at step 113 in comparison with each other. Then, the inspection guidance / execution unit 181 compares the installation positions 51 to 54 of the probe 50 of the current inspection with the installation positions 51 to 54 of the probe 50 of the previous inspection read in Step 110 and installs them. A positional deviation amount between the previous installation positions of positions 51 to 54 and the current installation position is detected.

  Specifically, the inspection inspection guidance / execution unit 181 determines the measurement probe installation positions 51 to 54 stored at the time of the previous inspection at Step 110 and the measurement probe installation positions 51 to 54 stored at the time of the current inspection at Step 113. The difference in position coordinates is obtained, and the amount of positional deviation is detected. The misregistration amount includes information on a deviated direction and a deviated distance.

  When the detected displacement amount is larger than a predetermined value, the inspection guide / implementing unit 181 performs a display on the first display unit 6 to prompt the operator to correct the installation position of the measurement probe. The case where the detected positional deviation amount is larger than a predetermined value is, for example, the measurement imaged at the time of the current inspection in step 113 with respect to the installation positions 51 to 54 of the measurement probe 50 imaged at the time of the previous inspection in step 110. This is a case where any one of the probe installation positions 51 to 54 is displaced by 5 mm or more. The inspection guide / execution unit 181 determines that the correction is not necessary because the measurement area is not affected if the shifted distance is within 5 mm. As a display for prompting the operator to correct the installation position of the measurement probe, for example, a display indicating the shifted direction in the direction of the arrow and the shifted distance in the size of the arrow is displayed on the first display unit 6.

  Also, the inspection guidance / execution unit 181 can detect the amount of displacement by performing image analysis on the image captured at the previous inspection read at step 110 and the image captured at the current inspection in step 113. Specifically, the image captured at the time of the previous inspection in step 110 and the image captured at the time of the current inspection in step 113 are subjected to image analysis, and the shape of the probe insertion opening 50a of the holder 16 (for example, a C shape) is displayed on the image. Extract (image recognition).

  Then, the inspection guide / execution unit 181 sets the position of the probe insertion port 50a at the center upper end among the plurality of probe insertion ports 50a recognized in the image captured at the previous inspection and the image captured at the current inspection. As the position 51, the position of the probe insertion port 50a at the lower end of the center is the measurement probe installation position 52, the position of the probe insertion port 50a at the lower right end is the measurement probe installation position 53, and the position of the probe insertion port 50a at the lower left end is the measurement probe. The installation positions 54 are detected respectively. The inspection guidance / execution unit 181 compares the positions of the measurement probe installation positions 51 to 54 when imaged at the previous inspection in step 110 with the positions of the measurement probe installation positions 51 to 54 when imaged at the current inspection in step 113. Thus, the amount of misalignment is detected. Then, when the detected displacement amount is larger than a predetermined value, the inspection guide / execution unit 181 displays on the first display unit 6 a prompt prompting the operator to correct the installation position of the measurement probe. .

  If the positional deviation amount is larger than a predetermined value and a display for prompting correction is displayed on the first display unit 6, the inspection guidance / execution unit 181 returns to Step 112. As the display for prompting the correction, for example, as in the case of the magnetic sensor 8, for example, a display in which the shifted direction is indicated by the direction of the arrow and the shifted distance is indicated by the size of the arrow.

  If the operator corrects the position of the measurement probe and selects the installation completion button, the process proceeds to step 113, where the image is taken again by the camera unit 5, and the installation positions 51 to 54 of the measurement probe 50 are measured by the magnetic sensor 8, The amount of positional deviation from the previous measurement is detected. These steps 112 and 113 are repeated until the amount of displacement of the measurement probe becomes a predetermined value or less.

  When the amount of displacement of the installation positions 51 to 54 of the measurement probe 50 is equal to or less than a predetermined value in step 113, the selection by the operator of the button 44 in the measurement parameter setting process on the screen 41 in FIG. 4 can be accepted. To do. If the operator selects this button 44, the examination guidance / execution unit 181 proceeds to step 114, and displays a screen for accepting measurement parameter setting input from the operator in the same manner as in step 105. Accept input. At this time, for example, as shown in FIG. 6, the inspection guidance / execution unit 181 displays the measurement parameter 62 read in the previous step 110 used in the previous inspection on the first display unit 6 as shown in the screen 61 of FIG. It is possible.

  If the measurement parameter setting of this time is accepted, the examination guidance / execution unit 181 compares the single hiragana character set as the stimulation task with the single hiragana character of the stimulation task used in the previous examination (previous measurement). When one character of the same hiragana is set, it is the same as the previous examination, and therefore a display for prompting resetting is displayed on the first display unit 6. At this time, the first display unit 6 displays the hiragana of the stimulation task used in the previous examination and the candidate hiragana of the stimulation task used in the current examination. The candidate for the stimulus task hiragana is a hiragana other than the stimulus task hiragana used in the previous examination.

  Specifically, as shown in FIG. 6, the examination guidance / execution unit 181 extracts the measurement parameter 62 used in the previous examination, and the hiragana of the stimulation task used in the previous examination. The first display unit 6 displays “to” for the second time and “na” for the third time for the stimulus. Then, the examination guidance / execution unit 181 displays “ki” for the first stimulation, “se” for the second stimulation, “o” for the second stimulation, and “o” for the third stimulation as the first stimulus unit 6 used in the examination. To display. The operator uses the operation unit 20 to set one hiragana character that is different from the hiragana used in the previous examination with reference to the candidate hiragana used in the current examination displayed on the first display unit 6.

  Note that the examination guidance / execution unit 181 can automatically select and set one hiragana character different from the one hiragana character used in the stimulation task used in the previous examination. In addition, the examination guidance / execution unit 181 performs “a”, “to”, “na”, “ki”, “se”, “o”, which are stimulation tasks used in the previous examination and the current examination, in future examinations performed after the current examination. It is also possible to select and set one hiragana character other than.

  The reason why hiragana different from the hiragana used in the previous examination is set in this way is that the task of recalling the same initial word as the previous examination in this examination is of low difficulty and cannot be measured accurately. . If one hiragana character of a stimulus task different from the previous examination is set, the examination guidance / execution unit 181 can accept selection by the operator of the measurement start button 45.

  If the operator selects the button 45, the process proceeds to step 115 and measurement is started. The measurement method is the same as in step 106. Proceeding to step 107, measurement is performed using the task set at step 114. Steps 107 to 108 are the same as the new measurement.

  As described above, in this embodiment, the inspection guidance / execution unit 181 guides the operator through the navigation screen 41 shown in FIG. 4 so that the upper process is not completed and the process cannot proceed to the lower process. Since the timing for enabling the selection of the button is controlled, even if the operator and the date, place, and apparatus for performing the inspection are different, the same process can be sequentially performed to perform a quality inspection.

  In addition, when re-inspecting the same subject (patient), the measurement probe can be installed at the same position as the previous measurement, and the inspection can be performed on a different task from the previous measurement. Since errors due to the displacement of the probe can be eliminated and the difficulty can be reduced by repeating the same task, data with good reproducibility with few errors can be acquired.

  For this reason, accuracy can be improved, for example, when performing disease determination using measurement data.

  Further, since the operator can be guided by the navigation screen 41, the operator can easily proceed with the inspection, and a user-friendly device can be provided.

  In the present embodiment, a case has been described in which a control task and a stimulation task are performed as an inspection method, and a mental illness is determined as necessary. However, the present invention is not limited to this inspection method, and biological light It can be applied to all inspections in measuring devices. For example, the present invention can be applied to a test that presents a category such as “animal, vehicle, food” instead of an initial letter and generates a word related to the category. It is also possible to present pictures and characters as images in addition to voice and apply them to visual inspections and cognitive inspections.

  Further, in steps 104 and 113 in FIG. 3, the subject in which the measurement probe is installed is photographed and the positional deviation amount between the previous measurement probe position and the current measurement probe position is obtained. It is also possible to store an image indicating the position of a measurement probe in the storage unit 19 and obtain the amount of positional deviation between this image and the probe position of the captured image.

  Further, in steps 104 and 113, the configuration in which both the external appearance imaging of the subject attached with the measurement probe by the camera and the position measurement of the measurement probe by the magnetic sensor have been described, but the configuration in which only one of them is performed is adopted. Is also possible. For example, it is possible to adopt a configuration in which an external appearance of a subject attached with a measurement probe by a camera is detected, the position of the measurement probe is detected by image processing, and measurement by a magnetic sensor is not performed. It is also possible to employ a configuration in which the position of the measurement probe is measured only with a magnetic sensor without imaging with a camera, and the amount of positional deviation is shown to the operator using an image prepared in advance.

DESCRIPTION OF SYMBOLS 1 ... Subject (patient), 2 ... Optical module part, 3 ... Operation processing part, 4 ... Speaker, 5 ... Camera part, 6 ... 1st display part, 7 ... 2nd display part, 11 ... Irradiation optical fiber, DESCRIPTION OF SYMBOLS 12 ... Detection optical fiber, 13 ... Light source, 14 ... Detector, 15 ... Detector, 16 ... Holder, 17 ... A / D converter, 18 ... Operation unit, 19 ... Memory | storage part, 20 ... Input part, 41 ... Navigation Screens 51-54 ... Measurement probe, 61 ... Screen for inputting measurement parameters, 181 ... Test guidance / execution unit, 182 ... Hemoglobin amount calculation unit, 183 ... Disease determination unit

Claims (8)

A light irradiating unit for irradiating the subject with light, a detecting unit for detecting light that has passed through the inside of the subject, and a control unit,
The said control part displays the several process which comprises a test | inspection, and the execution order of these several processes on a display apparatus, and performs the process according to the said execution order, The biological light measuring device characterized by the above-mentioned. 2. The biological light measurement apparatus according to claim 1, wherein the plurality of steps include at least one of an inspection explanation step, a step for prompting installation of a measurement probe, and a step for receiving measurement parameter settings from an operator, and a measurement step. Including
The measuring step is a step of irradiating the subject with light by detecting the light irradiating unit and the detecting unit, and detecting light that has passed through the inside of the subject. apparatus.   The biological light measurement device according to claim 2, wherein the control unit reproduces an image stored in a storage device in advance and displays the image on a display device as the examination explanation step.   The biological light measurement device according to claim 2, wherein the control unit images the subject to which the measurement probe is attached by the imaging device, and stores the image in the storage device.   The biological light measurement apparatus according to claim 4, wherein the control unit, as a step of prompting the installation of the measurement probe, includes an image at the previous inspection stored in the storage device and an image captured at the current inspection. A living body light measuring device characterized by comparing and detecting a displacement amount of the measuring probe.   The biological light measurement apparatus according to claim 2, wherein the control unit receives an input of a task to be executed by the subject from the operator as a step of receiving the setting of the measurement parameter from the operator, and stores the task. The living body light measuring device characterized by being stored in the body.   The biological light measurement device according to claim 6, wherein the control unit compares the problem used in the previous examination stored in the storage device with the problem input this time, and the problem is the same. In some cases, the biological light measurement device is characterized in that the display device is displayed to prompt the operator to change to a different task. The biological light measurement device according to claim 6 or 7, wherein the control unit displays the assignments used in the previous examination stored in the storage device and candidates for the assignments usable in the current examination. Display on the device,
A candidate for a problem that can be used in the current examination is a problem that is different from the problem used in the previous examination.

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