JP2011200517A - 電子内視鏡システム - Google Patents
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- 238000003384 imaging method Methods 0.000 claims description 85
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
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- A—HUMAN NECESSITIES
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- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00002—Operational features of endoscopes
- A61B1/00004—Operational features of endoscopes characterised by electronic signal processing
- A61B1/00009—Operational features of endoscopes characterised by electronic signal processing of image signals during a use of endoscope
- A61B1/000094—Operational features of endoscopes characterised by electronic signal processing of image signals during a use of endoscope extracting biological structures
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- A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
- A61B1/063—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements for monochromatic or narrow-band illumination
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- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
- A61B1/0638—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements providing two or more wavelengths
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
- A61B1/0655—Control therefor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
- A61B5/1459—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4887—Locating particular structures in or on the body
- A61B5/489—Blood vessels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/00147—Holding or positioning arrangements
- A61B1/00156—Holding or positioning arrangements using self propulsion
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/06—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements
- A61B1/0646—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with illuminating arrangements with illumination filters
Abstract
【解決手段】電子内視鏡システムは、波長帯域の異なる複数の光を順次照射する光源装置と、光源装置から体腔内の血管を含む被写体組織に順次照射される光の反射光を受光して、受光した光の波長帯域に対応する撮像信号を順次出力する電子内視鏡と、電子内視鏡から出力された、波長帯域の異なる光の撮像信号に対応する各々の画像間の位置合わせを行う位置合わせ手段と、位置合わせ手段により位置合わせが行われた各々の画像の撮像信号から、所定の深さの血管中の酸素飽和度の分布を表す酸素飽和度画像を生成する画像生成手段と、画像生成手段により生成された酸素飽和度画像を表示する画像表示手段とを備える。
【選択図】図2
Description
前記光源装置から体腔内の血管を含む被写体組織に順次照射される光の反射光を受光して、該受光した光の波長帯域に対応する撮像信号を順次出力する電子内視鏡と、
前記電子内視鏡から出力された、前記波長帯域の異なる光の撮像信号に対応する各々の画像間の位置合わせを行う位置合わせ手段と、
前記位置合わせ手段により位置合わせが行われた各々の画像の撮像信号から、所定の深さの血管中の酸素飽和度の分布を表す酸素飽和度画像を生成する画像生成手段と、
前記画像生成手段により生成された酸素飽和度画像を表示する画像表示手段とを備えることを特徴とする電子内視鏡システムを提供するものである。
前記光源装置は、前記撮像素子の各色のチャンネルの分光感度に対応した中心波長の狭帯域光を同時に照射するものであることが好ましい。
前記光源装置は、第1中心波長の狭帯域光の照射順序が、該第1中心波長の狭帯域光よりも前記被写体組織の特徴点情報を取得しやすい第2および第3中心波長の狭帯域光の間になるように照射するものであることが好ましい。
前記画像生成手段は、前記位置合わせ手段により位置合わせが行われた、前記狭帯域光の撮像信号および前記広帯域光の少なくとも1つの色のチャンネルの撮像信号から、前記酸素飽和度画像を生成するものであることが好ましい。
前記画像表示手段は、前記深さの異なる複数の血管の酸素飽和度画像を同時に表示するものであることが好ましい。
・表層血管:中心波長405,445,473nm
・中層血管:中心波長473,532,560nm
・深層血管:中心波長560,650,800nm
・表層血管:中心波長445,473nmの狭帯域光および広帯域光のGチャンネル
・深層血管:中心波長800nmの狭帯域光および広帯域光のRチャンネル
以上、本発明について詳細に説明したが、本発明は上記実施形態に限定されず、本発明の主旨を逸脱しない範囲において、種々の改良や変更をしてもよいのはもちろんである。
11 電子内視鏡
12 プロセッサ装置
13 光源装置
14 モニタ
16 挿入部
16a 先端部
17 操作部
18 ユニバーサルコード
19 湾曲部
21 アングルノブ
22 挿入口
24 コネクタ
30 広帯域光源
31 シャッター
32 シャッター駆動部
36 カプラー
37 光源切替部
39 集光レンズ
40 広帯域用光ファイバ
43 ライトガイド
44 CCD
44a 撮像面
45 アナログ処理回路
46 撮像制御部
48 照射レンズ
49 照明窓
50 観察窓
51 集光レンズ
52,53,54 分光透過率
55 デジタル信号処理部
56 フレームメモリ
57 血管画像生成部
58 表示制御回路
59 コントローラー
60 輝度比算出部
61 相関関係記憶部
62 血管深さ−酸素飽和度算出部
64 酸素飽和度画像生成部
64a〜64c カラーテーブル
65 画像位置合わせ処理部
66 輝度座標系
67 血管情報座標系
68 画像切替SW
70 還元ヘモグロビン
71 酸化ヘモグロビン
91〜97 第1〜第7狭帯域光源
91a〜97a 第1〜第7狭帯域用光ファイバ
Claims (9)
- 波長帯域の異なる複数の光を順次照射する光源装置と、
前記光源装置から体腔内の血管を含む被写体組織に順次照射される光の反射光を受光して、該受光した光の波長帯域に対応する撮像信号を順次出力する電子内視鏡と、
前記電子内視鏡から出力された、前記波長帯域の異なる光の撮像信号に対応する各々の画像間の位置合わせを行う位置合わせ手段と、
前記位置合わせ手段により位置合わせが行われた各々の画像の撮像信号から、所定の深さの血管中の酸素飽和度の分布を表す酸素飽和度画像を生成する画像生成手段と、
前記画像生成手段により生成された酸素飽和度画像を表示する画像表示手段とを備えることを特徴とする電子内視鏡システム。 - 前記光源装置は、前記波長帯域の異なる複数の光として、前記酸素飽和度に応じて、前記血管中の還元ヘモグロビンと酸化ヘモグロビンの吸光度の大小関係が逆転する波長帯域の少なくとも2つの第1光と、前記吸光度が同じになる波長帯域の少なくとも1つの第2光を照射するものであることを特徴とする請求項1に記載の電子内視鏡システム。
- 前記光源装置は、前記第1光および第2光として、中心波長±10nmの狭帯域光を照射するものであることを特徴とする請求項2に記載の電子内視鏡システム。
- 前記電子内視鏡は、前記受光した光を前記撮像信号に光電変換するカラーの撮像素子を有し、
前記光源装置は、前記撮像素子の各色のチャンネルの分光感度に対応した中心波長の狭帯域光を同時に照射するものであることを特徴とする請求項3に記載の電子内視鏡システム。 - 前記電子内視鏡は、前記受光した光を前記撮像信号に光電変換するモノクロの撮像素子を有し、
前記光源装置は、第1中心波長の狭帯域光の照射順序が、該第1中心波長の狭帯域光よりも前記被写体組織の特徴点情報を取得しやすい第2および第3中心波長の狭帯域光の間になるように照射するものであることを特徴とする請求項3に記載の電子内視鏡システム。 - 前記光源装置は、前記第1光および第2光として、さらに、470〜700nmの波長帯域の広帯域光を照射し、
前記画像生成手段は、前記位置合わせ手段により位置合わせが行われた、前記狭帯域光の撮像信号および前記広帯域光の少なくとも1つの色のチャンネルの撮像信号から、前記酸素飽和度画像を生成するものであることを特徴とする請求項3に記載の電子内視鏡システム。 - 前記画像生成手段は、深さの異なる複数の血管中の酸素飽和度の分布を表す酸素飽和度画像を生成し、
前記画像表示手段は、前記深さの異なる複数の血管の酸素飽和度画像を同時に表示するものであることを特徴とする請求項1〜6のいずれかに記載の電子内視鏡システム。 - 前記画像表示手段は、前記深さの異なる複数の血管の酸素飽和度画像を各々別々の2次元画像として同時に表示するものであることを特徴とする請求項7に記載の電子内視鏡システム。
- 前記画像表示手段は、前記深さの異なる複数の血管の酸素飽和度画像を1つの3次元画像として同時に表示するものであることを特徴とする請求項7に記載の電子内視鏡システム。
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JP2010071913A JP5405373B2 (ja) | 2010-03-26 | 2010-03-26 | 電子内視鏡システム |
EP11152067.2A EP2368485B1 (en) | 2010-03-26 | 2011-01-25 | Electronic endoscope system |
US13/016,113 US20110237883A1 (en) | 2010-03-26 | 2011-01-28 | Electronic endoscope system |
CN2011100364697A CN102197983A (zh) | 2010-03-26 | 2011-01-31 | 电子内窥镜系统 |
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CN (1) | CN102197983A (ja) |
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WO2014156604A1 (ja) * | 2013-03-26 | 2014-10-02 | 富士フイルム株式会社 | 内視鏡システム及びその作動方法並びにプロセッサ装置 |
JP2015173737A (ja) * | 2014-03-13 | 2015-10-05 | オリンパス株式会社 | 生体観察システム |
JP2015231467A (ja) * | 2014-06-10 | 2015-12-24 | 富士フイルム株式会社 | 内視鏡用光源装置及び内視鏡システム |
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US10517472B2 (en) | 2015-01-21 | 2019-12-31 | Hoya Corporation | Endoscope system |
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JP5623348B2 (ja) * | 2011-07-06 | 2014-11-12 | 富士フイルム株式会社 | 内視鏡システム、内視鏡システムのプロセッサ装置、及び内視鏡システムの作動方法 |
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JP2015231467A (ja) * | 2014-06-10 | 2015-12-24 | 富士フイルム株式会社 | 内視鏡用光源装置及び内視鏡システム |
JP2016000073A (ja) * | 2014-06-11 | 2016-01-07 | 富士フイルム株式会社 | 内視鏡用光源装置及び内視鏡システム |
JP2016067780A (ja) * | 2014-09-30 | 2016-05-09 | 富士フイルム株式会社 | 内視鏡システム、プロセッサ装置、内視鏡システムの作動方法、及びプロセッサ装置の作動方法 |
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JPWO2019130964A1 (ja) * | 2017-12-28 | 2021-01-28 | 富士フイルム株式会社 | 内視鏡画像取得システム及び方法 |
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US20110237883A1 (en) | 2011-09-29 |
CN102197983A (zh) | 2011-09-28 |
JP5405373B2 (ja) | 2014-02-05 |
EP2368485A3 (en) | 2012-01-04 |
EP2368485A2 (en) | 2011-09-28 |
EP2368485B1 (en) | 2016-03-23 |
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